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Journal Articles

Covalent-103: A Phase 1, Open-Label, Dose-Escalation, and Dose-Expansion Study of Bmf-500, an Oral Covalent FLT3 Inhibitor, in Adults with Acute Leukemia (AL)

Marcello Rotta, Farhad Ravandi, Mitul Gandhi, Paul B. Koller, Gary J. Schiller, Courtney Follit, Mona Vimal, Stephan W. Morris, Sanchita Mourya, Thomas Butler, Eunice S. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1546.
https://doi.org/10.1182/blood-2023-182361
Published: 2023
Journal Articles

Covalent Menin Inhibitor Bmf-219 in Patients with Relapsed or Refractory (R/R) Acute Leukemia (AL): Preliminary Phase 1 Data from the Covalent-101 Study

Jeffrey Lancet, Farhad Ravandi, Pau Montesinos, Jacqueline C. Barrientos, Talha Badar, Adrián Alegre, Asad Bashey, Juan Miguel Bergua Burgues, Lorenzo Brunetti, Emily K Curran, David C. Christian de Leeuw, Enrico Derenzini, Geert A. Huls, Jeroen J.W.M. Janssen, Deepa Jeyakumar, Mojca Jongen-Lavrencic, Ashwin Kishtagari, Maria-Victoria Mateos, Daniel Morillo, Alessandro Rambaldi, Aaron S. Rosenberg, Gary J. Schiller, Uzma Ahmed, Alexandru Cacovean, Stephan W. Morris, Courtney Follit, Brian Munneke, Ganesh Waghmare, Clarissa Mandap, Mona Vimal, Thomas Butler, Hetty E. Carraway
Journal: Blood
Blood (2023) 142 (Supplement 1): 2916.
https://doi.org/10.1182/blood-2023-173149
Published: 2023
Journal Articles

Bmf-500: An Orally Bioavailable Covalent Inhibitor of FLT3 with High Selectivity and Potent Antileukemic Activity in FLT3-Mutated AML

Brian Law, Tripta Rughwani, Tenley C. Archer, Lekha Kumar, Daniel Lu, Priyanka Somanath, Yan Ma, Xiaodong Wang, David Sperandio, Steve Morris, Thorsten Kirschberg, Mini Balakrishnan, Thomas Butler
Journal: Blood
Blood (2022) 140 (Supplement 1): 6191–6192.
https://doi.org/10.1182/blood-2022-170445
Published: 2022
Journal Articles

Novel Irreversible Menin Inhibitor, BMF-219, Shows Potent Single Agent Activity in Clinically Relevant DLBCL Cells

Priyanka Somanath, Daniel Lu, Brian Law, Tenley C. Archer, Alexandru Cacovean, James T. Palmer, Taisei Kinoshita, Thomas Butler
Journal: Blood
Blood (2021) 138 (Supplement 1): 4318.
https://doi.org/10.1182/blood-2021-148045
Published: 2021
Journal Articles

Investigation of the Significance of Son Isoform mRNA Expression in Patients with Blood Cytopenias with/without Evidence of Myeloid Neoplasia

Aaron Dinerman, Jung-Hyun Kim, PhD, Eun-Young Erin Ahn, PhD, Thomas Butler, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5293.
https://doi.org/10.1182/blood.V130.Suppl_1.5293.5293
Published: 2017
Journal Articles

Immunologically Targeting the Leukaemia Phosphoproteome

Hugo De La Peña, MD, PhD, Postdoc, Thomas Butler, Hsing-Wen Huang, Toral Jakhira, Chung-Yang Joseph, Sarah Penny, David Millar, Charles Craddock, Guy Pratt, Michael E. Williams, MD, Donald F Hunt, Victor H Engelhard, Mark Cobbold, PI
Journal: Blood
Blood (2010) 116 (21): 1016.
https://doi.org/10.1182/blood.V116.21.1016.1016
Published: 2010