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Journal Articles

Late Hematologic Recovery after CPX-351 Induction Chemotherapy in AML: Predictive Disease and Patient's Factors and Their Impact on Survival

Blood (2023) 142 (Supplement 1): 4275.

https://doi.org/10.1182/blood-2023-182993

Published: 2023

Journal Articles

Nuclear Condensates Are a Therapeutic Vulnerability in NPM1-Mutant Acute Myeloid Leukemia

Gandhar Datar, Archish Anand, Marwa Sadek, Evdokiia Potolitsyna, Christina Dollinger, English Laserna, Lorenzo Brunetti, Nidhi Sahni, Joshua Riback, Margaret Goodell

Blood (2023) 142 (Supplement 1): 1381.

https://doi.org/10.1182/blood-2023-191107

Published: 2023

Journal Articles

Applicability of SIE/Sies/GITMO Fitness Criteria to Therapy-Related and AML-MRC Receiving CPX-351: Results from a Large, Retrospective, Multicentric, Observational Study

Blood (2023) 142 (Supplement 1): 2891.

https://doi.org/10.1182/blood-2023-181142

Published: 2023

Journal Articles

Optimal Duration of CPX-351 Treatment and Best Timing for Consolidation with Allogeneic Stem Cell Transplantation: Evidence from a Large Real-World Italian Study

Blood (2023) 142 (Supplement 1): 731.

https://doi.org/10.1182/blood-2023-189025

Published: 2023

Journal Articles

Covalent Menin Inhibitor Bmf-219 in Patients with Relapsed or Refractory (R/R) Acute Leukemia (AL): Preliminary Phase 1 Data from the Covalent-101 Study

Blood (2023) 142 (Supplement 1): 2916.

https://doi.org/10.1182/blood-2023-173149

Published: 2023

Journal Articles

Overlapping features of therapy-related and de novo NPM1 -mutated AML

Blood (2023) 141 (15): 1846–1857.

https://doi.org/10.1182/blood.2022018108

Published: 2023

Includes: Supplemental data

Journal Articles

Nuclear Phase Separation Directs HOX Expression in Acute Myeloid Leukemia

Gandhar Datar, Archish Anand, Marwa Sadek, Christina Dollinger, English Laserna, Lorenzo Brunetti, Nidhi Sahni, Joshua Riback, Margaret A. Goodell

Blood (2022) 140 (Supplement 1): 724–725.

https://doi.org/10.1182/blood-2022-168430

Published: 2022

Journal Articles

Clonal Competition: Cisplatin Treatment Drives Dominance of TP53- over Tet2-Mutant Stem Cell Clones

Blood (2022) 140 (Supplement 1): 8590–8591.

https://doi.org/10.1182/blood-2022-164858

Published: 2022

Journal Articles

Mutant NPM1 Is Recruited to MLL Target Genes Via Its Acidic Stretch and Nuclear Export Factor CRM1 and Regulates Oncogenic Transcription in Acute Myeloid Leukemia

Hannah J Uckelmann, Elena L Haarer, Reina Takeda, Eric Wong, Christian Marinaccio, Charles Hatton, Yanhe Wen, Florian Perner, Masooma Rajput, Noa J.C. Antonissen, Chun-Wei David Chen, Lorenzo Brunetti, Scott A. Armstrong

Blood (2022) 140 (Supplement 1): 5835–5836.

https://doi.org/10.1182/blood-2022-166630

Published: 2022

Journal Articles

A Chemo-Free Bridge-to-Transplant Strategy with Venetoclax and Azacitidine for NPM1 -Mutated Acute Myeloid Leukemia in Molecular Failure

Chiara Sartor, Lorenzo Brunetti, Ernesta Audisio, Alessandro Cignetti, Letizia Zannoni, Gianluca Cristiano, Jacopo Nanni, Emanuela Ottaviani, Lorenza Bandini, Sarah Parisi, Stefania Paolini, Sofia Sciabolacci, Valeria Cardinali, Cristina Papayannidis, Michele Cavo, Maria Paola Martelli, Antonio Curti

Blood (2022) 140 (Supplement 1): 9034–9035.

https://doi.org/10.1182/blood-2022-165914

Published: 2022

Journal Articles

Novel NPM1 exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML

Blood (2021) 138 (25): 2696–2701.

https://doi.org/10.1182/blood.2021012732

Published: 2021

Includes: Supplemental data

Journal Articles

How I diagnose and treat NPM1 -mutated AML

Brunangelo Falini, Lorenzo Brunetti, Maria Paola Martelli

Blood (2021) 137 (5): 589–599.

https://doi.org/10.1182/blood.2020008211

Published: 2021

Journal Articles

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

May Daher, Rafet Basar, Elif Gokdemir, Natalia Baran, Nadima Uprety, Ana Karen Nunez Cortes, Mayela Mendt, Lucila Nassif Kerbauy, Pinaki P. Banerjee, Mayra Shanley, Nobuhiko Imahashi, Li Li, Francesca Lorraine Wei Inng Lim, Mohsen Fathi, Ali Rezvan, Vakul Mohanty, Yifei Shen, Hila Shaim, Junjun Lu, Gonca Ozcan, Emily Ensley, Mecit Kaplan, Vandana Nandivada, Mustafa Bdiwi, Sunil Acharya, Yuanxin Xi, Xinhai Wan, Duncan Mak, Enli Liu, Xin Ru Jiang, Sonny Ang, Luis Muniz-Feliciano, Ye Li, Jing Wang, Shahram Kordasti, Nedyalko Petrov, Navin Varadarajan, David Marin, Lorenzo Brunetti, Richard J. Skinner, Shangrong Lyu, Leiser Silva, Rolf Turk, Mollie S. Schubert, Garrett R. Rettig, Matthew S. McNeill, Gavin Kurgan, Mark A. Behlke, Heng Li, Natalie W. Fowlkes, Ken Chen, Marina Konopleva, Richard E. Champlin, Elizabeth J. Shpall, Katayoun Rezvani

Blood (2021) 137 (5): 624–636.

https://doi.org/10.1182/blood.2020007748

Published: 2021

Includes: Supplemental data

Journal Articles

NPM1 -mutated acute myeloid leukemia: from bench to bedside

Brunangelo Falini, Lorenzo Brunetti, Paolo Sportoletti, Maria Paola Martelli

Blood (2020) 136 (15): 1707–1721.

https://doi.org/10.1182/blood.2019004226

Published: 2020

Journal Articles

Precise Modeling of IKZF1 Alterations in Human B-Cell Acute Lymphoblastic Leukemia Cell Lines Reveals Distinct Chemosensitivity, Homing, and Engraftment Properties

Jason H. Rogers, MS, Rohit Gupta, BS, Jaime M. Reyes, BS, Lorenzo Brunetti, MD PhD, Michael C. Gundry, BS, Tidie Song, Cade Johnson, Carlo D. D. Cristobal, BS, Margaret A. Goodell, PhD, Rachel E. Rau, MD

Blood (2018) 132 (Supplement 1): 549.

https://doi.org/10.1182/blood-2018-99-113056

Published: 2018

Journal Articles

Acute Myeloid Leukemia with Mutated NPM1 Is Dependent on the Cytoplasmic Localization of NPM1c

Lorenzo Brunetti, MD, Michael Gundry, Anna Guzman, Ilaria Gionfriddo, PhD, Federica Mezzasoma, PhD, Francesca Milano, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, MD, Margaret Goodell, PhD

Blood (2017) 130 (Supplement 1): 877.

https://doi.org/10.1182/blood.V130.Suppl_1.877.877

Published: 2017

Journal Articles

Loss of De Novo DNA Methyltransferase DNMT3A Impacts Alternative Splicing in Hematopoietic Stem Cells

Raghav Ramabadran, BS, Jarey Wang, Anna Guzman, Sean Michael Cullen, MD PhD, Lorenzo Brunetti, MD, Michael Gundry, Sunny Chan, PhD, Michael Kyba, PhD, Thomas Westbrook, PhD, Margaret Goodell, PhD

Blood (2017) 130 (Supplement 1): 1.

https://doi.org/10.1182/blood.V130.Suppl_1.1.1

Published: 2017

Journal Articles

Two-Pronged Cell Therapy for B-Cell Malignancies: Engineering NK Cells to Target CD22 and Redirect Bystander T Cells to CD19

Mireya Paulina Velasquez, MD, Arpad Szoor, MD PhD, Challice L. Bonifant, MD PhD, Abishek Vaidya, Lorenzo Brunetti, MD, Michael C Gundry, BS, Robin Parihar, MD PhD, Margaret Goodell, PhD, Stephen Gottschalk, MD

Blood (2016) 128 (22): 4560.

https://doi.org/10.1182/blood.V128.22.4560.4560

Published: 2016

Journal Articles

Fast and Efficient Gene Editing in Human Hematopoietic Cells

Michael C Gundry, BS, Lorenzo Brunetti, MD, Dimitrios Laurin Wagner, Joanne Hsu, BS, Mireya Paulina Velasquez, MD, Stephen Gottschalk, MD, Cliona M. Rooney, PhD, Margaret Goodell, PhD

Blood (2016) 128 (22): 4704.

https://doi.org/10.1182/blood.V128.22.4704.4704

Published: 2016

Journal Articles

Arsenic trioxide and all- trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1 -mutated AML cells

Maria Paola Martelli, Ilaria Gionfriddo, Federica Mezzasoma, Francesca Milano, Sara Pierangeli, Floriana Mulas, Roberta Pacini, Alessia Tabarrini, Valentina Pettirossi, Roberta Rossi, Calogero Vetro, Lorenzo Brunetti, Paolo Sportoletti, Enrico Tiacci, Francesco Di Raimondo, Brunangelo Falini

Blood (2015) 125 (22): 3455–3465.

https://doi.org/10.1182/blood-2014-11-611459

Published: 2015

Includes: Supplemental data

NARROW

Late Hematologic Recovery after CPX-351 Induction Chemotherapy in AML: Predictive Disease and Patient's Factors and Their Impact on Survival

Nuclear Condensates Are a Therapeutic Vulnerability in NPM1-Mutant Acute Myeloid Leukemia

Applicability of SIE/Sies/GITMO Fitness Criteria to Therapy-Related and AML-MRC Receiving CPX-351: Results from a Large, Retrospective, Multicentric, Observational Study

Optimal Duration of CPX-351 Treatment and Best Timing for Consolidation with Allogeneic Stem Cell Transplantation: Evidence from a Large Real-World Italian Study

Covalent Menin Inhibitor Bmf-219 in Patients with Relapsed or Refractory (R/R) Acute Leukemia (AL): Preliminary Phase 1 Data from the Covalent-101 Study

Overlapping features of therapy-related and de novo NPM1 -mutated AML

Nuclear Phase Separation Directs HOX Expression in Acute Myeloid Leukemia

Clonal Competition: Cisplatin Treatment Drives Dominance of TP53- over Tet2-Mutant Stem Cell Clones

Mutant NPM1 Is Recruited to MLL Target Genes Via Its Acidic Stretch and Nuclear Export Factor CRM1 and Regulates Oncogenic Transcription in Acute Myeloid Leukemia

A Chemo-Free Bridge-to-Transplant Strategy with Venetoclax and Azacitidine for NPM1 -Mutated Acute Myeloid Leukemia in Molecular Failure

Novel NPM1 exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML

How I diagnose and treat NPM1 -mutated AML

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

NPM1 -mutated acute myeloid leukemia: from bench to bedside

Precise Modeling of IKZF1 Alterations in Human B-Cell Acute Lymphoblastic Leukemia Cell Lines Reveals Distinct Chemosensitivity, Homing, and Engraftment Properties

Acute Myeloid Leukemia with Mutated NPM1 Is Dependent on the Cytoplasmic Localization of NPM1c

Loss of De Novo DNA Methyltransferase DNMT3A Impacts Alternative Splicing in Hematopoietic Stem Cells

Two-Pronged Cell Therapy for B-Cell Malignancies: Engineering NK Cells to Target CD22 and Redirect Bystander T Cells to CD19

Fast and Efficient Gene Editing in Human Hematopoietic Cells

Arsenic trioxide and all- trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1 -mutated AML cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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