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Journal Articles

Clonal evolution dissection reveals that a high MSI2 level promotes chemoresistance in T-cell acute lymphoblastic leukemia

Jingliao Zhang, Yongjuan Duan, Peng Wu, Yanxia Chang, Yue Wang, Tianyuan Hu, Chao Liu, Xiaoyan Chen, Suyu Zong, Xiaoli Chen, Yangping Wu, Linlin Jin, Yang Lan, Xiaoming Liu, Xuelian Cheng, Feng Ding, Tianyu Li, Xiaojuan Chen, Ye Guo, Yumei Chen, Wenyu Yang, Li Zhang, Yao Zou, Tao Cheng, Xiaofan Zhu, Yingchi Zhang
Journal: Blood
Blood (2024) 143 (4): 320–335.
https://doi.org/10.1182/blood.2023020490
Published: 2024
Includes: Supplemental data
Journal Articles

Clonal Competition: Cisplatin Treatment Drives Dominance of TP53- over Tet2-Mutant Stem Cell Clones

Katharina Wohlan, Lorenzo Brunetti, Joanne I. Hsu, Katie A. Matatall, Rebecca L. Murdaugh, Linda Zhang, Anna Guzman, Jack Toups, Daniel Hormaechea-Agulla, Carina Rosas, Meghan Kisiel, Ayumi Kitano, Tianyuan Hu, Yu-Jung Tseng, Bailee N. Kain, Sara Biesiadny, Jonathan Tiessen, Minhua Li, Marcus Florez, Sarah Waldvogel, Kristen Kurtz, Mira Jeong, Duy Le, Daniel E. Morales-Mantilla, Hannah Yan, Alejandra Garcia Martell, Chiraag D. Kapadia, Yung-Hsin Huang, Shannon E. Conneely, Rogelio Aguilar, Xiangguo Shi, Tianpeng Gu, Hyojeong Han, Yajian Jiang, Jason Rogers, Taishi Yonezawa, Apoorva Thatavarty, Ruoqiong Cao, Trisha K. Wathan, Nesa Mercer, Daniel Kennedy, Ayala Tovy, Jaime M. Reyes, Marek Kimmel, Yun Huang, Daisuke Nakada, Katherine Y. King, Margaret A. Goodell
Journal: Blood
Blood (2022) 140 (Supplement 1): 8590–8591.
https://doi.org/10.1182/blood-2022-164858
Published: 2022
Journal Articles

AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia

Yajian Jiang, Tianyuan Hu, Tao Wang, Xiangguo Shi, Ayumi Kitano, Kenneth Eagle, Kevin A. Hoegenauer, Marina Y. Konopleva, Charles Y. Lin, Nicolas L. Young, Daisuke Nakada
Journal: Blood
Blood (2019) 134 (24): 2183–2194.
https://doi.org/10.1182/blood.2019001076
Published: 2019
Includes: Supplemental data
Journal Articles

Adult Hematopoietic Stem and Progenitor Cell Maintenance Requires Histone Variant H3.3 Regulation By Hira

Rebecca Murdaugh, BS, Kevin Hoegenauer, Xiangguo Shi, PhD, Ayumi Kitano, Richard Chapple, PhD, Tianyuan Hu, PhD, Jonathan Tiessen, BS, Daisuke Nakada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2473.
https://doi.org/10.1182/blood-2019-131358
Published: 2019
Journal Articles

Targeting NMNAT1 in Acute Myeloid Leukemia

Xiangguo Shi, PhD, Daisuke Nakada, PhD, Ayumi Kitano, Rebecca Murdaugh, BS, Yu-Jung Tseng, BS,MS, Kevin Hoegenauer, Tianyuan Hu, PhD, Yajian Jiang, BS
Journal: Blood
Blood (2019) 134 (Supplement_1): 879.
https://doi.org/10.1182/blood-2019-132139
Published: 2019
Journal Articles

Hematopoietic Hierarchy Under Steady-State and Stress Conditions

Yu-Jung Tseng, BS,MS, Richard Chapple, PhD, Tianyuan Hu, PhD, Kimal Rajapakshe, Kevin Hoegenauer, BS, Cristian Coarfa, PhD, Daisuke Nakada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1181.
https://doi.org/10.1182/blood-2019-125110
Published: 2019
Journal Articles

PRDM16s transforms megakaryocyte-erythroid progenitors into myeloid leukemia–initiating cells

Tianyuan Hu, Kiyomi Morita, Matthew C. Hill, Yajian Jiang, Ayumi Kitano, Yusuke Saito, Feng Wang, Xizeng Mao, Kevin A. Hoegenauer, Kazuhiro Morishita, James F. Martin, P. Andrew Futreal, Koichi Takahashi, Daisuke Nakada
Journal: Blood
Blood (2019) 134 (7): 614–625.
https://doi.org/10.1182/blood.2018888255
Published: 2019
Includes: Supplemental data
Journal Articles

AMPK Protects Against Energy Stress and Maintains Histone Acetylation in Leukemia-Initiating-Cell

Yajian Jiang, MBBS, Daisuke Nakada, PhD, Ayumi Kitano, Richard Chapple, MS, Tianyuan Hu, PhD, Angelique Lin, BS
Journal: Blood
Blood (2016) 128 (22): 2701.
https://doi.org/10.1182/blood.V128.22.2701.2701
Published: 2016
Journal Articles

PDK1 Controls the Differentiation of Hematopoietic Stem Cells Via Modulating ROS Levels

Tianyuan Hu, PhD, Cong Li, Le Wang, Yingchi Zhang, Luyun Peng, Weili Wang, Xiaomin Wang, Yajing Chu, Yingdai Gao, Bing Liu, Zhenyu Ju, Tao Cheng, MD, Weiping Yuan, PhDMD
Journal: Blood
Blood (2015) 126 (23): 896.
https://doi.org/10.1182/blood.V126.23.896.896
Published: 2015