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Journal Articles

Clonal evolution dissection reveals that a high MSI2 level promotes chemoresistance in T-cell acute lymphoblastic leukemia

Jingliao Zhang, Yongjuan Duan, Peng Wu, Yanxia Chang, Yue Wang, Tianyuan Hu, Chao Liu, Xiaoyan Chen, Suyu Zong, Xiaoli Chen, Yangping Wu, Linlin Jin, Yang Lan, Xiaoming Liu, Xuelian Cheng, Feng Ding, Tianyu Li, Xiaojuan Chen, Ye Guo, Yumei Chen, Wenyu Yang, Li Zhang, Yao Zou, Tao Cheng, Xiaofan Zhu, Yingchi Zhang
Journal: Blood
Blood (2024) 143 (4): 320–335.
https://doi.org/10.1182/blood.2023020490
Published: 2024
Includes: Supplemental data
Journal Articles

Diverse Effects of Cryopreservation-Induced Mitochondrial Dysregulation on Cord Blood Cells

Yaojin Huang, Mengyao Liu, Xiaowei Xie, Yawen Zhang, Fang Dong, Yingchi Zhang, Tao Cheng
Journal: Blood
Blood (2023) 142 (Supplement 1): 3524.
https://doi.org/10.1182/blood-2023-184410
Published: 2023
Journal Articles

Corelationship of Lymphocyte Subsets and Prognosis in Juvenile Myelomonocytic Leukemia

Yunlong Chen, Jingliao Zhang, Fang Liu, Yingchi Zhang, Xiaofan Zhu, Wenyu Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6496.
https://doi.org/10.1182/blood-2023-184515
Published: 2023
Journal Articles

Clonal Evolution Dissection Reveals High MSI2 Level Promotes Chemo-Resistance in T-Cell Acute Lymphoblastic Leukemia

Jingliao Zhang, Yongjuan Duan, Peng Wu, Suyu Zong, Wenyu Yang, Li Zhang, Tao Cheng, Xiaofan Zhu, Yingchi Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 846.
https://doi.org/10.1182/blood-2023-189334
Published: 2023
Journal Articles

Single Cell Analysis Highlights Th17-Polarized CD4 + Naive T Cells with JAK3/STAT3 Pathway Activation in Pediatric Severe Aplastic Anemia

Jingliao Zhang, Tianfeng Liu, Yanxia Chang, Yongjuan Duan, Chao Liu, Xiaoyan Chen, Cheng Tao, Xiaofan Zhu, Yingchi Zhang
Journal: Blood
Blood (2022) 140 (Supplement 1): 475–476.
https://doi.org/10.1182/blood-2022-164551
Published: 2022
Journal Articles

Multi-Omics Analysis of Human Mesenchymal Stem Cell Guides Perinatal MSC Based Cellular Therapy for Splenectomy-Nonresponsive Refractory Immune Thrombocytopenia: A Phase I Clinical Trial

Yuchen Gao, Ying Chi, Yunfei Chen, Hui Yuan Li, Wentian Wang, Wenting Zheng, Ping Zhu, Jinying An, Yanan Duan, Ting Sun, Liu Xiaofan, Feng Xue, Wei Liu, Rongfeng Fu, Zhibo Han, Yingchi Zhang, Renchi Yang, Cheng Tao, Jun Wei, Xiaomin Zhang, Lei Zhang
Journal: Blood
Blood (2022) 140 (Supplement 1): 1974–1976.
https://doi.org/10.1182/blood-2022-156764
Published: 2022
Journal Articles

Preliminary Safety and Efficacy Results of EDI001: An Investigator Initiated Trial on CRISPR/Cas9-Modified Autologous CD34 + Hematopoietic Stem and Progenitor Cells for Patients with Transfusion Dependent β-Thalassemia

Jun Shi, Riguo Fang, Zhen Gao, Zhongyu Shi, Zhexiang Kuang, Yongjian Zhang, Lele Zhang, Huihui Yang, Yingchi Zhang, Dehui Zou, Liwei Fang, Jiali Sun, Qiang Li, Yao Zou, Hong Pan, Jingyu Zhao, Liyun Li, Xiao Yu, Jing Xu, Chun Xu, Yanjie Liu, Weiwei Wang, Jia Shi, Jie Liu, Jia Wang, Nian Shi, Lei Yang, Weiqiang Wang, Suyi Li, Moye Shi, Xiaoshuang Zhang, Pengfei Yuan, Wensheng Wei, Dong Wei, Tao Cheng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10652–10653.
https://doi.org/10.1182/blood-2022-166365
Published: 2022
Journal Articles

Decoding Clonal Evolution in Relapsed T Cell Acute Lymphoblastic Leukemia at Single Cell Resolution

Jingliao Zhang, Yongjuan Duan, Yanxia Chang, Yue Wang, Chao Liu, Ye Guo, Xiaojuan Chen, Li Zhang, Xiaofan Zhu, Yingchi Zhang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3482.
https://doi.org/10.1182/blood-2021-153299
Published: 2021
Journal Articles

Single-Cell Decoding of Minimal Residual Disease in Pediatric B Cell Acute Lymphoblastic Leukemia

Yingchi Zhang, Shicheng Wang, Jingliao Zhang, Chao Liu, Xinqi Li, Xiaofan Zhu, Jin Gu, Cheng Tao
Journal: Blood
Blood (2021) 138 (Supplement 1): 2385.
https://doi.org/10.1182/blood-2021-152789
Published: 2021
Journal Articles

Correlation Analysis of DNA Methylation Level and Clinical Characteristics in JMML Patients

Yuli Cai, Jingliao Zhang, Meihui Yi, Xiaoming Liu, Xiaoyan Zhang, Yang Wan, Lixian Chang, Li Zhang, Xiaojuan Chen, Ye Guo, Yao Zou, Yumei Chen, Yingchi Zhang, Wenyu Yang, Xiaofan Zhu
Journal: Blood
Blood (2021) 138 (Supplement 1): 3699.
https://doi.org/10.1182/blood-2021-150044
Published: 2021
Journal Articles

Highly Efficient Gene Editing of Human Hematopoietic Stem Cells to Treat X-Linked Sideroblastic Anemia

Riguo Fang, PhD, Yingchi Zhang, PhD, Pengfei Yuan, PhD, Huihui Yang, Master, Lingling Yu, Bachelor, Yongjian Zhang, PhD, Jia Shi, PhD, Guangzhen Ji, PhD, Jingliao Zhang, MD, Wei Qi, Master, Xiaofan Zhu, MD, Dong Wei, PhD, Tao Cheng
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-140208
Published: 2020
Journal Articles

Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia

Benshang Li, Samuel W. Brady, Xiaotu Ma, Shuhong Shen, Yingchi Zhang, Yongjin Li, Karol Szlachta, Li Dong, Yu Liu, Fan Yang, Ningling Wang, Diane A. Flasch, Matthew A. Myers, Heather L. Mulder, Lixia Ding, Yanling Liu, Liqing Tian, Kohei Hagiwara, Ke Xu, Xin Zhou, Edgar Sioson, Tianyi Wang, Liu Yang, Jie Zhao, Hui Zhang, Ying Shao, Hongye Sun, Lele Sun, Jiaoyang Cai, Hui-Ying Sun, Ting-Nien Lin, Lijuan Du, Hui Li, Michael Rusch, Michael N. Edmonson, John Easton, Xiaofan Zhu, Jingliao Zhang, Cheng Cheng, Benjamin J. Raphael, Jingyan Tang, James R. Downing, Ludmil B. Alexandrov, Bin-Bing S. Zhou, Ching-Hon Pui, Jun J. Yang, Jinghui Zhang
Journal: Blood
Blood (2020) 135 (1): 41–55.
https://doi.org/10.1182/blood.2019002220
Published: 2020
Includes: Supplemental data
Journal Articles

FLT3 pathway is a potential therapeutic target for PRC2-mutated T-cell acute lymphoblastic leukemia

Jingliao Zhang, Yingchi Zhang, Man Zhang, Chao Liu, Xiaoming Liu, Jie Yin, Peng Wu, Xiaojuan Chen, Wenyu Yang, Li Zhang, Ye Guo, Yao Zou, Yumei Chen, Youjia Cao, Tao Cheng, Xiaofan Zhu
Journal: Blood
Blood (2018) 132 (23): 2520–2524.
https://doi.org/10.1182/blood-2018-04-845628
Published: 2018
Includes: Supplemental data
Journal Articles

Mutational Landscape and Temporal Evolution during Treatment of Relapsed Acute Lymphoblastic Leukemia

Benshang Li, Yongjin Li, PhD, Shuhong Shen, MD PhD, Yingchi Zhang, Samuel Brady, PhD, Xiaotu Ma, Yu Liu, PhD, Ningling Wang, Diane Flasch, Matthew Myers, Heather Mulder, BS, Yanling Liu, Liqing Tian, Kohei Hagiwara, MD, Hui Zhang, Ying Shao, Hongye Sun, Lele Sun, Ting-Nien Lin, Lijuan Du, Fan Yang, Michael Rusch, BS, Michael Edmonson, John Easton, PhD, Xiaofan Zhu, PhD, Jingliao Zhang, MD, Cheng Cheng, PhD, Benjamin Raphael, Jing-Yan Tang, James R. Downing, MD, Bin-Bing Zhou, Ching-Hon Pui, MD, Jun J. Yang, PhD, Jinghui Zhang
Journal: Blood
Blood (2018) 132 (Supplement 1): 917.
https://doi.org/10.1182/blood-2018-99-119144
Published: 2018
Journal Articles

PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia

CME Brief Report
Yingchi Zhang, Yufeng Gao, Hui Zhang, Jingliao Zhang, Fuhong He, Aleš Hnízda, Maoxiang Qian, Xiaoming Liu, Yoshihiro Gocho, Ching-Hon Pui, Tao Cheng, Qianfei Wang, Jun J. Yang, Xiaofan Zhu, Xin Liu
Journal: Blood
Blood (2018) 131 (20): 2256–2261.
https://doi.org/10.1182/blood-2017-11-817510
Published: 2018
Includes: Supplemental data
Journal Articles

Clinical Implication of Gene Mutations in Children Myelodysplastic Syndromes

Wenbin An, Chao Liu, Shuai Zhu, Yang Wan, Yingchi Zhang, PhD, Xiaofan Zhu, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1688.
https://doi.org/10.1182/blood.V130.Suppl_1.1688.1688
Published: 2017
Journal Articles

Aberrant FLT3 Transcription Arised from Polycomb Repressive Complex 2 Inactivation Indiactes a Potential Therapy Target for Pediatric T Cell Acute Lymphoblastic Leukemia

Jingliao Zhang, Ye Guo, Wenyu Yang, Xiaojuan Chen, Liu Chao, Yumei Chen, Yao Zou, Yingchi Zhang, PhD, Xiaofan Zhu, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 368.
https://doi.org/10.1182/blood.V130.Suppl_1.368.368
Published: 2017
Journal Articles

Mutation Profiling Reveals Novel Epigenetics and Splicing Mutations in Chemorefractory Pediatric AML

Yingchi Zhang, PhD, Di Zhan, Peifang Xiao, MD, MIN Ruan, Jingliao Zhang, Gang Huang, PhD, Shaoyan Hu, MD PhD, Qianfei Wang, PhD, Xiaofan Zhu, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3817.
https://doi.org/10.1182/blood.V130.Suppl_1.3817.3817
Published: 2017
Journal Articles

A Landscape of Transcriptome Sequencing in Childhood Immune Thrombocytopenia(ITP)

Congcong Sun, PhD, Lixian Chang, PhD, Yanling Lv, Liu Chao, Chenghai Xue, Shunli Yang, Yang Lan, Xiaoyan Chen, Yingchi Zhang, PhD, Jinxia Guan, Xiaofan Zhu, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1051.
https://doi.org/10.1182/blood.V130.Suppl_1.1051.1051
Published: 2017
Journal Articles

Mutation of a GATA1 Binding Site in ALAS2 Intron 1 Arrests Murine Erythroid Development In Vivo

Yingchi Zhang, Jingliao Zhang, Wenbin An, Yang Wan, MD, Jie Gao, Lihong Shi, Tao Cheng, MD, Xiaofan Zhu, MD
Journal: Blood
Blood (2016) 128 (22): 2425.
https://doi.org/10.1182/blood.V128.22.2425.2425
Published: 2016