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Journal Articles

Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion

Clinical Trials & Observations
Xinyi Xia, Kening Li, Lingxiang Wu, Zhihua Wang, Mengyan Zhu, Bin Huang, Jie Li, Ziyu Wang, Wei Wu, Min Wu, Wanlin Li, Lu Li, Yun Cai, Bakwatanisa Bosco, Aifang Zhong, Xiong Liu, Tangfeng Lv, Zhenhua Gan, Guang Chen, Yunhu Pan, Caidong Liu, Kai Zhang, Xiaoli Xu, Changjun Wang, Qianghu Wang
Journal: Blood
Blood (2020) 136 (6): 755–759.
https://doi.org/10.1182/blood.2020007079
Published: 2020
Includes: Supplemental data
Journal Articles

First-in-Human, Phase 1/2 Trial to Assess the Safety and Clinical Activity of Subcutaneous GEN3013 (DuoBody ® -CD3×CD20) in B-Cell Non-Hodgkin Lymphomas

Pieternella Lugtenburg, MD PhD, Rogier Mous, MD PhD, Michael Roost Clausen, Martine E.D. Chamuleau, Peter Johnson, MDFRCP, Kim Linton, PhD, Simon Rule, Roberto S Oliveri, MD PhD, Dena DeMarco, Ida H Hiemstra, PhD, Guang Chen, Ada Azaryan, Manish Gupta, Tahamtan Ahmadi, Martin Hutchings, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 758.
https://doi.org/10.1182/blood-2019-121460
Published: 2019
Journal Articles

Integrated Analysis of Randomized Controlled Trials Evaluating Bortezomib + Lenalidomide + Dexamethasone or Bortezomib + Thalidomide + Dexamethasone Induction in Transplant-Eligible Newly Diagnosed Multiple Myeloma

Laura Rosinol Dachs, Benjamin Hebraud, Albert Oriol, MD, Anne-Laurène Colin, Rafael Rios, MD PhD, Cyrille Hulin, Maria Jesús Blanchard, MD, Denis Caillot, Anna Sureda, MD, Miguel T Hernández, MD PhD, Bertrand Arnulf, Maria-Victoria Mateos, MD PhD, Margaret Macro, Jesús F San-Miguel, MD, Karim Belhadj, Juan Jose Lahuerta, MD PhD, Guang Chen, M. Brigid Garelik, Joan Bladé, MD, Philippe Moreau, Michel Attal, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3245.
https://doi.org/10.1182/blood-2018-99-112659
Published: 2018
Journal Articles

Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma

Clinical Trials & Observations
Thierry Facon, Meletios A. Dimopoulos, Angela Dispenzieri, John V. Catalano, Andrew Belch, Michele Cavo, Antonello Pinto, Katja Weisel, Heinz Ludwig, Nizar J. Bahlis, Anne Banos, Mourad Tiab, Michel Delforge, Jamie D. Cavenagh, Catarina Geraldes, Je-Jung Lee, Christine Chen, Albert Oriol, Javier De La Rubia, Darrell White, Daniel Binder, Jin Lu, Kenneth C. Anderson, Philippe Moreau, Michel Attal, Aurore Perrot, Bertrand Arnulf, Lugui Qiu, Murielle Roussel, Eileen Boyle, Salomon Manier, Mohamad Mohty, Herve Avet-Loiseau, Xavier Leleu, Annette Ervin-Haynes, Guang Chen, Vanessa Houck, Lotfi Benboubker, Cyrille Hulin
Journal: Blood
Blood (2018) 131 (3): 301–310.
https://doi.org/10.1182/blood-2017-07-795047
Published: 2018
Includes: Supplemental data
Journal Articles

Final Analysis of Overall Survival from the First Trial

Thierry Facon, Meletios A Dimopoulos, Angela Dispenzieri, John V. Catalano, Andrew Belch, Michele Cavo, MD, Antonello Pinto, Katja Weisel, Heinz Ludwig, Nizar J. Bahlis, MD, Anne Banos, Mourad Tiab, Michel Delforge, Jamie D. Cavenagh, Catarina Geraldes, Je-Jung Lee, Christine Chen, Albert Oriol, Javier De La Rubia, Darrell White, Daniel Binder, Jin Lu, Kenneth C. Anderson, Philippe Moreau, Michel Attal, Jean-Paul Fermand, Herve Avet-Loiseau, Annette Ervin-Haynes, Guang Chen, Vanessa Houck, Cyrille Hulin, Lofti Benboubker
Journal: Blood
Blood (2016) 128 (22): 241.
https://doi.org/10.1182/blood.V128.22.241.241
Published: 2016
Journal Articles

Impact of Cytogenetics on Outcomes of Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma Treated with Continuous Lenalidomide Plus Low-Dose Dexamethasone in the First (MM-020) Trial

Herve Avet-Loiseau, Cyrille Hulin, Lofti Benboubker, Meletios A. Dimopoulos, Andrew Belch, Donna Reece, John Catalano, Antonio Pinto, Heinz Ludwig, Nizar J Bahlis, Michele Cavo, Michel Attal, Philippe Moreau, Lugui Qiu, Richard LeBlanc, Rik Schots, S. Vincent Rajkumar, Jennifer Marek, Guang Chen, Wai Yiu, Annette Ervin-Haynes, Thierry Facon
Journal: Blood
Blood (2015) 126 (23): 730.
https://doi.org/10.1182/blood.V126.23.730.730
Published: 2015
Journal Articles

Continuous Treatment with Lenalidomide and Low-Dose Dexamethasone in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma in Asia: Subanalysis of the First Trial

Jin Lu, Jae Hoon Lee, Shang-Yi Huang, Lugui Qiu, Je-Jung Lee, Ting Liu, Sung-Soo Yoon, Kihyun Kim, Zhi Xiang Shen, HyeonSeok Eom, Wenming Chen, Chang-Ki Min, Hyo Jung Kim, Jeong Ok Lee, Jae Yong Kwak, Wai Yiu, Guang Chen, Annette Ervin Haynes, Cyrille Hulin, Thierry Facon
Journal: Blood
Blood (2015) 126 (23): 4240.
https://doi.org/10.1182/blood.V126.23.4240.4240
Published: 2015
Journal Articles

Impact of Response Quality on Survival Outcomes in Transplant-Ineligible Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts): Results from the First Trial

Nizar J Bahlis, MD, Alessandro Corso, Lars-Olof Mugge, Zhi-Xiang Shen, Pierre Desjardins, Anne-Marie Stoppa, MD, Olivier Decaux, Thierry De Revel, Miquel Granell, Gerald Marit, Hareth Nahi, Hilde Demuynck, Shang-Yi Huang, Supratik Basu, Troy H. Guthrie, Annette Ervin-Haynes, Nicolas Leupin, Jennifer Marek, Guang Chen, Thierry Facon
Journal: Blood
Blood (2014) 124 (21): 3458.
https://doi.org/10.1182/blood.V124.21.3458.3458
Published: 2014
Journal Articles

The Broad Activity of the CD33/CD3 Bispecific BiTE® Antibody AMG 330 in Primary Human AML Is Impacted By Disease Stage and Cytogenetic/Molecular Risk

Kimberly H. Harrington, BS, Chelsea J. Gudgeon, BS, George S. Laszlo, PhD, Kathryn J. Newhall, PhD, Angus M. Sinclair, PhD, Stanley R. Frankel, MD, Roman Kischel, MD, Guang Chen, PhD, Roland B. Walter, MD PhD MS
Journal: Blood
Blood (2014) 124 (21): 266.
https://doi.org/10.1182/blood.V124.21.266.266
Published: 2014
Journal Articles

Effect of Age on Efficacy and Safety Outcomes in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) Receiving Lenalidomide and Low-Dose Dexamethasone (Rd): The First Trial

Cyrille Hulin, MD, Thierry Facon, MD, Chaim Shustik, MD, Andrew Belch, MD, Maria Teresa Petrucci, MD, Ulrich Dührsen, MD, Jin Lu, MD, Kevin Song, MD, Philippe Rodon, Brigitte Pegourie, MD, Laurent Garderet, MD, Hannah Hunter, Isabelle Azais, MD, Richard Eek, MD, Margaret Macro, MD, Shaker Dakhil, MD FACP, Vanessa Houck, Guang Chen, Annette Ervin-Haynes, Fritz Offner, MD
Journal: Blood
Blood (2014) 124 (21): 81.
https://doi.org/10.1182/blood.V124.21.81.81
Published: 2014
Journal Articles

Impact of Renal Impairment (RI) on Outcomes after Treatment (Tx) with Lenalidomide and Low-Dose Dexamethasone (Rd) in Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts): First Trial Results

Meletios A. Dimopoulos, Matthew C Cheung, Murielle Roussel, MD, Ting Liu, Barbara Gamberi, MD, Brigitte Kolb, H. Guenter Derigs, Hyeon Seok Eom, Karim Belhadj, Pascal Lenain, Richard H. van der Jagt, Sophie Rigaudeau, Mamoun Dib, Rachel Hall, Arnaud Jaccard, MD, Axel Tosikyan, Lionel Karlin, William Bensinger, Rik Schots, Guang Chen, Jennifer Marek, Annette Ervin-Haynes, Thierry Facon
Journal: Blood
Blood (2014) 124 (21): 2112.
https://doi.org/10.1182/blood.V124.21.2112.2112
Published: 2014
Journal Articles

Initial Phase 3 Results Of The First (Frontline Investigation Of Lenalidomide + Dexamethasone Versus Standard Thalidomide) Trial (MM-020/IFM 07 01) In Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts) Ineligible For Stem Cell Transplantation (SCT)

Thierry Facon, MD, Meletios A. Dimopoulos, MD, Angela Dispenzieri, MD, John V. Catalano, MD, Andrew R Belch, MD, Cyrille Hulin, MD, Michele Cavo, MD, Antonella Pinto, MD, Katja Weisel, MD, Heinz Ludwig, MD, Nizar J. Bahlis, MD, Anne Banos, MD, Mourad Tiab, MD, Michel Delforge, MD, PhD, James D Cavenagh, MD, Catarina Geraldes, MD, Je-Jung Lee, MD, PhD, Christine I. Chen, MD, Albert Oriol, MD, Javier De La Rubia, MD, PhD, Lugui Qiu, MD, Darrell J. White, MD, Daniel Binder, MD, Kenneth C. Anderson, MD, Philippe Moreau, MD, Michel Attal, MD, Robert Knight, MD, Guang Chen, PhD, Jason Van Oostendorp, Christian J. Jacques, MD, Annette Ervin-Haynes, DO, Lofti Benboubker, MD
Journal: Blood
Blood (2013) 122 (21): 2.
https://doi.org/10.1182/blood.V122.21.2.2
Published: 2013
Journal Articles

MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4

Qiang Wang, Zheng Huang, Huiling Xue, Chengcheng Jin, Xiu-Li Ju, Jing-Dong J. Han, Ye-Guang Chen
Journal: Blood
Blood (2008) 111 (2): 588–595.
https://doi.org/10.1182/blood-2007-05-092718
Published: 2008
Journal Articles

MCP-1 mediates TGF-β–induced angiogenesis by stimulating vascular smooth muscle cell migration

Jing Ma, Qiang Wang, Teng Fei, Jing-Dong Jackie Han, Ye-Guang Chen
Journal: Blood
Blood (2006) 109 (3): 987–994.
https://doi.org/10.1182/blood-2006-07-036400
Published: 2006
Journal Articles

Functional analysis of mutations in the kinase domain of the TGF-β receptor ALK1 reveals different mechanisms for induction of hereditary hemorrhagic telangiectasia

Yi Gu, Peng Jin, Long Zhang, Xingang Zhao, Xia Gao, Yuanheng Ning, Anming Meng, Ye-Guang Chen
Journal: Blood
Blood (2006) 107 (5): 1951–1954.
https://doi.org/10.1182/blood-2005-05-1834
Published: 2006