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Elaine R Mardis
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Journal Articles

Ubtf- Tandem Duplications Are Recurrent Somatic Genetic Events in Adult AML and Associate with Additional Structural Variants and a Distinct Gene Expression Profile (Alliance)

Emily K Curran, Deedra Nicolet, Alejandro Otero-Bravo, Krzysztof Mrózek, Ben Kelly, Christopher J. Walker, Jill Buss, Andrea Laganson, Yazan Abu-Shihab, Alice Mims, William Blum, Jonathan E Kolitz, Bayard L Powell, Geoffrey L Uy, Wendy Stock, Richard M Stone, Andrew J Carroll, John C. Byrd, Elaine R Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 4312.
https://doi.org/10.1182/blood-2023-186722
Published: 2023
Journal Articles

The Genomic and Transcriptomic Landscape of Myeloid Sarcoma and Associated Acute Myeloid Leukemia

Bettina Nadorp, Audrey Lasry, Sanam Loghavi, Ravi Patel, Ben Kelly, Christopher J. Walker, Stephanie LaHaye, Jill Buss, Isaiah Boateng, Karen Nahmod, Adrienne Heyrosa, Helee Desai, Andrea Langanson, Hasan Abaza, Linda Procell, Tejas Patel, Benjamin Kaffenberger, Saranga Wijeratne, Maria Guillamot Ruano, Anna Yeaton, Geraldine Cayanan, Maria Velegraki, Zihai Li, Kieran D Sahasrabudhe, Lynne V. Abruzzo, Daniel Pollyea, Christine M. McMahon, Arwa Shana'Ah, John C. Byrd, Aristotelis Tsirigos, Elaine R Mardis, Alice Mims, Iannis Aifantis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 292.
https://doi.org/10.1182/blood-2023-182967
Published: 2023
Journal Articles

Genomic Profiles and Associated Survival Prognosticators in Black Patients with Acute Myeloid Leukemia

Andrew Stiff, Deedra Nicolet, Maarten Fornerod, Ben Kelly, Katherine Miller, Krzysztof Mrózek, Isaiah Boateng, Bailee Nicole Kain, Elizabeth Garfinkle, Eileen Y Hu, Saranga Wijeratne, Gregory Wheeler, Christopher J. Walker, Jill Buss, Adrienne Heyrosa, Helee Desai, Andrea Laganson, Yazan Abu-Shihab, Hasan Abaza, Alice Mims, Christopher C. Oakes, Bethany L Mundy-Bosse, Andrew J Carroll, Bayard L Powell, Jonathan E Kolitz, Richard Stone, Electra D Paskett, Ross L Levine, Kamal Menghrajani, Debyani Chakravarty, Michael F. Berger, Nathan Salomonis, Daniel Bottomly, Shannon K McWeeney, Jeffrey W Tyner, John C. Byrd, H. Leighton Grimes, Elaine R Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 837.
https://doi.org/10.1182/blood-2023-181876
Published: 2023
Journal Articles

Characterization of Comparative Clinical Outcomes and Molecular Features of Black Patients with Acute Promyelocytic Leukemia (APL) Reveals Similar Survival and Distinct Genomic Profiles

Alma Habib, Isaiah Boateng, Deedra Nicolet, Krzysztof Mrózek, James L Fisher, Allyson Waller, Andrew Stiff, Jill Buss, Andrea Laganson, Sienna Martinez Corzine, Ethan Hamp, Yazan Abu-Shihab, Bayard L Powell, Geoffrey L Uy, Wendy Stock, Richard M Stone, Jonathan E Kolitz, Eunice S. Wang, Andrew J Carroll, Jeffrey W Tyner, Andrew Hantel, Electra D Paskett, John C. Byrd, Elaine R Mardis, Jesse J Plascak, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 389.
https://doi.org/10.1182/blood-2023-182376
Published: 2023
Journal Articles

I-DATA Study: Randomized, Sequential, Open-Label Study to Evaluate the Efficacy of IDH Targeted/Non- Targeted Versus Non-Targeted/IDH-Targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated Adult AML Patients Not Candidates for Intensive Induction Therapy

Michael P Ozga, Kaitlyn M. Dvorak-Kornaus, Qiuhong Zhao, Jill Buss, Andrea Laganson, Ethan Hamp, Yazan F. Madanat, Daniel A. Pollyea, Eytan M. Stein, Joshua F. Zeidner, Elaine R Mardis, Ann-Kathrin Eisfeld, Alice Mims
Journal: Blood
Blood (2023) 142 (Supplement 1): 1534.
https://doi.org/10.1182/blood-2023-187060
Published: 2023
Journal Articles

Manufacture and Immunological Characterization of GMP-Compliant Functional Sars-COV-2 Cytotoxic T Lymphocytes (CTLs) Utilizing the Clinimacs ® Cytokine Capture System

Yaya Chu, Jordan Milner, Margaret Lamb, Elena Maryamchik, Olivia Rigot, Janet Ayello, Lauren Harrison, Rosemarie Shaw, Greg K. Behbehani, Elaine R. Mardis, Katherine E Miller, Lakshmi Prakruthi Rao Venkata, Hsiaochi Chang, Dean Anthony Lee, Elana Y. Rosenthal, Stephan Kadauke, Nancy Bunin, Julie-An Talano, Bryon Johnson, Yongping Wang, Mitchell S. Cairo
Journal: Blood
Blood (2021) 138 (Supplement 1): 476.
https://doi.org/10.1182/blood-2021-145620
Published: 2021
Journal Articles

High Early Death Rates, Treatment Resistance and Short Survival of Black Adolescent and Young Adults (AYAs) with Acute Myeloid Leukemia (AML) (Alliance)

Karilyn Larkin, Deedra Nicolet, Ben Kelly, Krzysztof Mrózek, Katherine E Miller, Saranga Wijeratne, Stephanie LaHaye, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Isaiah Boateng, Jill Buss, Adrienne Heyrosa, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, Electra D. Paskett, John C. Byrd, Elaine R. Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 221.
https://doi.org/10.1182/blood-2021-151072
Published: 2021
Journal Articles

TP53 Germline Variations Influence the Predisposition and Prognosis of Acute Lymphoblastic Leukemia in Children

Maoxiang Qian, PhD, Xueyuan Cao, PhD, Meenakshi Devidas, PhD, Wenjian Yang, PhD, Cheng Cheng, PhD, Andrew Carroll, PhD, Nyla A. Heerema, PhD, Hui Zhang, PhD MD, Takaya Moriyama, MDPhD, Julie M. Gastier-Foster, PhD, Heng Xu, PhD, Elizabeth A. Raetz, MD, Eric Larsen, MD, Naomi Winick, MD, W. Paul Bowman, MD, Paul L. Martin, MD PhD, Elaine R. Mardis, PhD, Robert Fulton, MS, Gerard Zambetti, PhD, Michael Borowitz, MD PhD, Brent Wood, MDPhD, Kim E. Nichols, MD, William L. Carroll, MD, Ching-Hon Pui, MD, Charles G. Mullighan, MBBS, MD, William E. Evans, PharmD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, Mignon L. Loh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 31.
https://doi.org/10.1182/blood.V130.Suppl_1.31.31
Published: 2017
Journal Articles

Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia

Michelle L. Churchman, PhD, Maoxiang Qian, PhD, Ranran Zhang, MD, Geertruy Kronnie, PhD, Wenjian Yang, PhD, Hui Zhang, MD, PhD, Tobia Lana, Paige Tedrick, Rebekah Baskin, PhD, Katherine Verbist, PhD, Meenakshi Devidas, PhD, Elizabeth Raetz, MD, Eric Larsen, MD, Paul L. Martin, MD PhD, W. Paul Bowman, Naomi Winick, MD, Elaine R Mardis, PhD, Robert S. Fulton, PhD, Martin Stanulla, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Ching-Hon Pui, MD, Rupert Handgretinger, MD, Stephen P. Hunger, Mignon L. Loh, MD, Kim E. Nichols, MD, Charles Mullighan, MBBS, MSc, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2016) 128 (22): LBA-2.
https://doi.org/10.1182/blood.V128.22.LBA-2.LBA-2
Published: 2016
Journal Articles

Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML

Brief Report
Terrence N. Wong, Christopher A. Miller, Jeffery M. Klco, Allegra Petti, Ryan Demeter, Nichole M. Helton, Tiandao Li, Robert S. Fulton, Sharon E. Heath, Elaine R. Mardis, Peter Westervelt, John F. DiPersio, Matthew J. Walter, John S. Welch, Timothy A. Graubert, Richard K. Wilson, Timothy J. Ley, Daniel C. Link
Journal: Blood
Blood (2016) 127 (7): 893–897.
https://doi.org/10.1182/blood-2015-10-677021
Published: 2016
Includes: Supplemental data
Journal Articles

Non-Malignant Oligoclonal Hematopoiesis Commonly Follows Cytoreductive Chemotherapy in Adult De Novo AML Patients

Terrence Neal Wong, MDPhD, Jeffery M. Klco, MDPhD, Ryan Demeter, Christopher A. Miller, PhD, Allegra Petti, PhD, Nichole Havey, Robert Fulton, PhD, Sharon Heath, Elaine R Mardis, PhD, Peter Westervelt, MD PhD, John F. DiPersio, MD PhD, Matthew J. Walter, MD, John S. Welch, MD PhD, Timothy Graubert, MD, Richard K Wilson, PhD, Timothy J. Ley, MD, Daniel C. Link, MD
Journal: Blood
Blood (2015) 126 (23): 686.
https://doi.org/10.1182/blood.V126.23.686.686
Published: 2015
Journal Articles

Expression of an Oncogenic ERG isoform Characterizes a Distinct Subtype of B-Progenitor Acute Lymphoblastic Leukemia

Jinghui Zhang, PhD, Kelly McCastlain, Chunxu Qu, PhD, Gang Wu, PhD, Michael Edmonson, PhD, Yongjin Li, PhD, Lei Wei, PhD, Debbie Payne-Turner, BS, Hiroki Yoshihara, MDPhD, Michelle L. Churchman, PhD, Esmé Waanders, PhD, Panagiotis Ntziachristos, PhD, Iannis Aifantis, PhD, Kathryn G. Roberts, Jing Ma, PhD, Guangchun Song, PhD, John Easton, PhD, Heather L. Mulder, BS, Xiang Chen, PhD, Michael Rusch, BA, Kristy Boggs, PhD, Bhavin Vadodaria, BS, James Dalton, BS, Marcus L Valentine, PhD, Li Ding, PhD, Charles Lu, PhD, Robert S. Fulton, PhD, Lucinda Fulton, PhD, Yashodan Tabib, PhD, Kerri Ochoa, Meenakshi Devidas, PhD, Deqing Pei, Cheng Cheng, PhD, William E. Evans, PharmD, Ching-Hon Pui, MD, Sima Jeha, MD, Richard C. Harvey, PhD, I-Ming L Chen, DVM, MS, Cheryl L. Willman, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD, Jessica Kohlschmidt, PhD BS, MS, Krzysztof Mrozek, MD PhD, Elisabeth Paietta, PhD, Martin S. Tallman, MD, Wendy Stock, MD, Peter M. Voorhees, MD, Janis Racevskis, MD, Jacob M. Rowe, MD, Selina Luger, MD, Steven M. Kornblau, MD, Sheila A Shurtleff, PhD, Susana C. Raimondi, PhD, Elaine R Mardis, PhD, Richard K Wilson, PhD, Stephen P Hunger, MD, Mignon L. Loh, MD, James R. Downing, MD, Charles G. Mullighan
Journal: Blood
Blood (2015) 126 (23): 693.
https://doi.org/10.1182/blood.V126.23.693.693
Published: 2015
Journal Articles

Germline Genetic Variation in ETV6 and Predisposition to Childhood Acute Lymphoblastic Leukemia

Takaya Moriyama, MD, Monika Metzger, MD, Gang Wu, PhD, Rina Nishii, Maoxiang Qian, PhD, Meenakshi Devidas, PhD, Wenjian Yang, PhD, Emily Quinn, MS, Julie Gastier-Foster, PhD, Elizabeth Raetz, MD, Eric C. Larsen, MD, Paul L. Martin, MD PhD, W. Paul Bowman, MD, Naomi J. Winick, MD, Yoshihiro Komada, MD PhD, Elaine R Mardis, PhD, Robert Fulton, PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Jinghui Zhang, PhD, Stephen P Hunger, MD, Mary V. Relling, PharmD, Kim E Nichols, MD, Mignon Loh, MD, Jun J Yang, PhD
Journal: Blood
Blood (2015) 126 (23): 695.
https://doi.org/10.1182/blood.V126.23.695.695
Published: 2015
Journal Articles

A Second Generation, Multiple Myeloma-Specific, Targeted Sequencing Platform for Detecting Translocations, Copy Number Alterations, and Single Nucleotide Variants

Brian S White, PhD, Irena Lanc, PhD, Daniel Auclair, PhD, Robert Fulton, PhD, Mark A Fiala, BS, CCRP, Justin King, Gregory Ahmann, BS, Mary Derome, MS, Elaine R Mardis, PhD, Joan Levy, PhD, Ravi Vij, MD MBA, John F. DiPersio, MD PhD, Michael Tomasson, MD
Journal: Blood
Blood (2015) 126 (23): 4207.
https://doi.org/10.1182/blood.V126.23.4207.4207
Published: 2015
Journal Articles

Recurrent Somatic Genomic Alterations in Follicular NHL (FL) Revealed By Exome and Custom-Capture Next Generation Sequencing

Todd A Fehniger, MD PhD, Kilannin Krysiak, PhD, Brian S White, PhD, Matthew Matlock, Chris Miller, Robert Fulton, PhD, Friederike Kreisel, MD, Catrina Fronick, Lisa Cook, Joelle Veizer, Amanda F. Cashen, MD, Kenneth R Carson, MD PhD, Melissa M Berrien-Elliott, PhD, Nancy L Bartlett, MD, Richard K Wilson, PhD, Elaine R Mardis, PhD, Timothy J Ley, Malachi Griffith, Obi L Griffith
Journal: Blood
Blood (2015) 126 (23): 574.
https://doi.org/10.1182/blood.V126.23.574.574
Published: 2015
Journal Articles

Genetic Risk Factors for the Development of Osteonecrosis in Children Under Age 10 Treated for Acute Lymphoblastic Leukemia

Seth E. Karol, MD, Wenjian Yang, PhD, Leonard A. Mattano, Jr., MD, Kelly W. Maloney, MD, Colton Smith, PhD, Chengcheng Liu, B.S, Laura B. Ramsey, PhD, Christian A. Fernandez, PhD, Tamara Y. Chang, MD, Geoffrey A. Neale, PhD, Cheng Cheng, PhD, Elaine R Mardis, PhD, Robert S. Fulton, PhD, Paul Scheet, PhD, Eric C. Larsen, MD, Mignon L. Loh, MD, Elizabeth Raetz, MD, Stephen P Hunger, MD, Meenakshi Devidas, PhD, Mary V. Relling, PharmD
Journal: Blood
Blood (2015) 126 (23): 250.
https://doi.org/10.1182/blood.V126.23.250.250
Published: 2015
Journal Articles

Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice

Elise Peterson Lu, Michael McLellan, Li Ding, Robert Fulton, Elaine R. Mardis, Richard K. Wilson, Christopher A. Miller, Peter Westervelt, John F. DiPersio, Daniel C. Link, Matthew J. Walter, Timothy J. Ley, Timothy A. Graubert
Journal: Blood
Blood (2014) 124 (26): 3887–3895.
https://doi.org/10.1182/blood-2014-06-582551
Published: 2014
Includes: Supplemental data
Journal Articles

Incidence of Germline Mutations in Cancer-Predisposition Genes in Children with Hematologic Malignancies: a Report from the Pediatric Cancer Genome Project

Michael Walsh, MD, Gang Wu, PhD, Michael Edmonson, PhD, Tanja A Gruber, MD PhD, John Easton, PhD, Donald Yergeau, PhD, Bhavin Vadodaria, BA, Xiaotu Ma, PhD, Xiang Chen, PhD, Rose McGee, MS, CGC, Christine Odom, MS, CGC, Sheila A Shurtleff, PhD, Matthew Parker, PhD, Michael Rusch, BA, Erin Hedlund, PhD, Robert Huether, PhD, Gordon Lemmon, PhD, Joy Nakitandwe, PhD, Jared Becksfort, MS, Panduka Nagahawatte, MS, Li Dong, PhD, Amanda Larson Gedman, PhD, Zachary J Faber, PhD, Jinjun Cheng, MD PhD, Jinjun Dang, PhD, Ching-Hon Pui, MD, Kim E Nichols, MD, Amar Gajjar, MD, David W Ellison, MD, Alberto Pappo, MD, Charles G. Mullighan, MBBS, MSc, MD, Elaine R Mardis, PhD, Richard K Wilson, PhD, Jinghui Zhang, PhD, James R Downing, MD
Journal: Blood
Blood (2014) 124 (21): 127.
https://doi.org/10.1182/blood.V124.21.127.127
Published: 2014
Journal Articles

Dysregulation and Recurrent Mutation Of miRNA-142 In De Novo AML

Maria Trissal, B.S., Jessica Silva, PhD, Todd Wylie, BS, Jasreet Hundal, MS, Sean McGrath, MS, Vincent Magrini, PhD, Giridharan Ramsingh, M.D, Elaine R. Mardis, PhD, Timothy J. Ley, MD, Daniel C. Link, MD
Journal: Blood
Blood (2013) 122 (21): 472.
https://doi.org/10.1182/blood.V122.21.472.472
Published: 2013
Journal Articles

The Role Of Early TP53 Mutations On The Evolution Of Therapy-Related AML

Terrence Neal Wong, MD PhD, Giridharan Ramsingh, M.D, Andrew Young, Dong Shen, Chris Miller, PhD, Tamara Lamprecht, B.S., Sharon Heath, Robert S. Fulton, Elaine R. Mardis, PhD, Li Ding, Peter Westervelt, MD, PhD, John Welch, PhD/MD, Matthew J. Walter, MD, Timothy Graubert, MD, John F. DiPersio, MD, PhD, Timothy J. Ley, MD, Todd E Druley, MD, PhD, Richard K Wilson, PhD, Daniel C. Link, MD
Journal: Blood
Blood (2013) 122 (21): 5.
https://doi.org/10.1182/blood.V122.21.5.5
Published: 2013