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Maria L Amaya
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Journal Articles

Evaluation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) with Missing Molecular Data

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, David A Sallman, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4607.
https://doi.org/10.1182/blood-2023-187053
Published: 2023
Journal Articles

Validation of the Composite Complete Response (cCR) Definitions in the International Working Group (IWG) 2023 Criteria in Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) Treated with Hypomethylating Agents (HMA) - a Large, Multicenter, Retrospective Analysis from the Validate Database

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 324.
https://doi.org/10.1182/blood-2023-180299
Published: 2023
Journal Articles

Outcomes of Haplo-Cord and Dual-Cord Transplants: A Single-Center Retrospective Analysis

Michael K Jones, Andrew Kent, Kellen Gil, Enkhtsetseg Purev, Bradley M. Haverkos, Marc Schwartz, Christine M. McMahon, Maria L Amaya, Grace N Bosma, Rachel Rabinovitch, Daniel A. Pollyea, Jonathan A Gutman
Journal: Blood
Blood (2023) 142 (Supplement 1): 7084.
https://doi.org/10.1182/blood-2023-190558
Published: 2023
Journal Articles

Mitochondrial STAT3 Plays a Critical Role in Survival of AML Cells

Kellen Gil, Jamie Borg, Anagha Inguva Sheth, Rosana Pereira, Jeremy Rahkola, Maria L Amaya
Journal: Blood
Blood (2023) 142 (Supplement 1): 4170.
https://doi.org/10.1182/blood-2023-179453
Published: 2023
Journal Articles

Consolidation with Ponatinib Plus Sequential Blinatumomab and Chemotherapy after Low Intensity Dasatinib-Based Induction in Adults with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Outcomes from a Single Institution

Marc Schwartz, Christine M. McMahon, Maria L Amaya, Matthew Witkowski, Daniel A. Pollyea, Jonathan A Gutman, Mohd Minhajuddin, Clayton Smith, Craig T. Jordan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4247.
https://doi.org/10.1182/blood-2023-188118
Published: 2023
Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Who Underwent Allogenic Stem Cell Transplantation (HSCT)

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Ameera Rose, Gail J. Roboz, Eunice S. Wang, Benjamin Rolles, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4980.
https://doi.org/10.1182/blood-2023-186578
Published: 2023
Journal Articles

Socioeconomic Status Is a Mediator of Overall Survival in Acute Myeloid Leukemia (AML)

Cassandra Duarte, Diana Abbott, Grace N Bosma, Christine M. McMahon, Jonathan A Gutman, Marc Schwartz, Daniel Pollyea, Maria L Amaya
Journal: Blood
Blood (2023) 142 (Supplement 1): 5176.
https://doi.org/10.1182/blood-2023-174996
Published: 2023
Journal Articles

Impact of Type of Hypomethylating Agent (HMA) Used on Outcomes of Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) - a Large, Multicenter, Retrospective Analysis

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Rahul Ramaswamy, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Carmelo Gurnari, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4613.
https://doi.org/10.1182/blood-2023-178728
Published: 2023
Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Who Were Treated with Hypomethylating Agents (HMA)

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Rahul Ramaswamy, Ameera Rose, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3240.
https://doi.org/10.1182/blood-2023-186340
Published: 2023
Journal Articles

A Qualitative Study Comparing the Patient and Provider Experience in an Academic Blood Disorder Center

Hunter Tolison, Cassandra Duarte, Glen Peterson, Grace N Bosma, Diana Abbott, Gemlyn George, Daniel Pollyea, Craig T. Jordan, Maria L Amaya
Journal: Blood
Blood (2023) 142 (Supplement 1): 3688.
https://doi.org/10.1182/blood-2023-179669
Published: 2023
Journal Articles

Results from a Phase (Ph) 1 Clinical Study of the All-Oral Regimen of CC-486 and Venetoclax for Relapsed and Refractory Acute Myeloid Leukemia

Maria L Amaya, Christine M. McMahon, Marc Schwartz, Jonathan A Gutman, Connor Sohalski, Jennifer Tobin, Austin E Gillen, Anagha Inguva Sheth, Brett M Stevens, Clayton Smith, Craig T. Jordan, Daniel A. Pollyea
Journal: Blood
Blood (2023) 142 (Supplement 1): 2914.
https://doi.org/10.1182/blood-2023-182966
Published: 2023
Journal Articles

Clinical Implications of TP53 Mutations/Allelic State in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Treated with Hypomethylating Agents (HMA)- a Multicenter, Retrospective Analysis from the Validate Database

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Hunter Cochran, Rahul Ramaswamy, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, David A Sallman, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1002.
https://doi.org/10.1182/blood-2023-186875
Published: 2023
Journal Articles

Targeting Mitochondrial Calcium Uptake to Eradicate Venetoclax-Resistant Acute Myeloid Leukemia Stem Cells

Anagha Inguva Sheth, Krysta Engel, Hunter Tolison, Mark Jordan Althoff, Anna Krug, Maria L Amaya, Shanshan Pei, Tracy Young, Sweta B Patel, Mohd Minhajuddin, Regan Miller, Ian Shelton, Ana Vujovic, Courtney L Jones, Austin E Gillen, Monica Ransom, Sarah Staggs, Clayton Smith, Daniel A. Pollyea, Brett M Stevens, Craig T. Jordan
Journal: Blood
Blood (2023) 142 (Supplement 1): 588.
https://doi.org/10.1182/blood-2023-188285
Published: 2023
Journal Articles

Age-Adapted Chemotherapy for Adults >40 Years Old with Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia: Single Center Outcomes

Marc Schwartz, Jonathan A Gutman, Christine M. McMahon, Maria L Amaya, Daniel A. Pollyea, Matthew Witkowski, Mohd Minhajuddin, Clayton Smith, Craig T. Jordan
Journal: Blood
Blood (2023) 142 (Supplement 1): 5898.
https://doi.org/10.1182/blood-2023-188298
Published: 2023
Journal Articles

Higher-Dose Venetoclax with Measurable Residual Disease-Guided Azacitidine Discontinuation in Newly Diagnosed Patients with Acute Myeloid Leukemia: Phase 2 Hiddav Study

Jonathan A. Gutman, Amanda C. Winters, Andrew Kent, Maria L. Amaya, Christine M. McMahon, Clayton Smith, Craig T Jordan, Brett M. Stevens, Mohammad Minhajuddin, Shanshan Pei, Jeffrey Schowinsky, Jennifer Tobin, Kelly O'Brien, Angela Falco, Elizabeth Taylor, Constance Brecl, Phuong Ho, Connor Sohalski, Jessica Dell-Martin, Olivia Ondracek, Diana Abbott, Daniel A. Pollyea
Journal: Blood
Blood (2022) 140 (Supplement 1): 3275–3276.
https://doi.org/10.1182/blood-2022-157802
Published: 2022
Journal Articles

Intracellular Calcium Localization Mediates the Activity of Venetoclax in Targeting Acute Myeloid Leukemia Stem Cells

Anagha Inguva, Krysta L. Engel, Hunter Tolison, Mark J Althoff, Shanshan Pei, Maria L. Amaya, Anna Krug, Mohammad Minhajuddin, Courtney L Jones, Austin E. Gillen, Monica Ransom, Sarah Staggs, Daniel A. Pollyea, Clayton Smith, Brett M. Stevens, Craig T. Jordan
Journal: Blood
Blood (2022) 140 (Supplement 1): 5922–5923.
https://doi.org/10.1182/blood-2022-167787
Published: 2022
Journal Articles

Response to Intensive Induction Chemotherapy after Failure of Frontline Azacitidine+Venetoclax in Acute Myeloid Leukemia

Christine M. McMahon, Kellen Gil, Maria L. Amaya, Jonathan A. Gutman, Alexander Hayden, Marc Schwartz, Grace Bosma, Diana Abbott, Brett M. Stevens, Clayton Smith, Craig T Jordan, Daniel A. Pollyea
Journal: Blood
Blood (2022) 140 (Supplement 1): 6185–6186.
https://doi.org/10.1182/blood-2022-170168
Published: 2022
Journal Articles

Clinical and Molecular Features of Highly Durable Response to Azacitidine+Venetoclax in Acute Myeloid Leukemia

Alexander Hayden, Grace Bosma, Jonathan A. Gutman, Maria L. Amaya, Diana Abbott, Clayton Smith, Brett M. Stevens, Craig T. Jordan, Daniel A. Pollyea, Christine M. McMahon
Journal: Blood
Blood (2022) 140 (Supplement 1): 9163–9164.
https://doi.org/10.1182/blood-2022-171064
Published: 2022
Journal Articles

The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation

Maria L. Amaya, Anagha Inguva, Shanshan Pei, Courtney Jones, Anna Krug, Haobin Ye, Mohammad Minhajuddin, Amanda Winters, Steffanie L. Furtek, Fabia Gamboni, Brett Stevens, Angelo D’Alessandro, Daniel A. Pollyea, Philip Reigan, Craig T. Jordan
Journal: Blood
Blood (2022) 139 (4): 584–596.
https://doi.org/10.1182/blood.2021013201
Published: 2022
Includes: Supplemental data
Journal Articles

Targeting MDS Stem Cells with Omacetaxine and Azacitidine for Newly Diagnosed High Grade Patients: Phase 1 Trial Results and Preliminary Mechanistic Studies

Brett M. Stevens, Amanda C. Winters, Mohammad Minhajuddin, Maria L. Amaya, Christine M. McMahon, Jonathan A. Gutman, Clayton Smith, Deng Wang, Connor Adkins, Olivia Ondracek, Craig T. Jordan, Daniel A. Pollyea
Journal: Blood
Blood (2021) 138 (Supplement 1): 2612.
https://doi.org/10.1182/blood-2021-150824
Published: 2021