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Jean Fan
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Journal Articles

Single-cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib

Noelia Purroy, Yuzhou Evelyn Tong, Camilla K. Lemvigh, Nicoletta Cieri, Shuqiang Li, Erin M. Parry, Wandi Zhang, Laura Z. Rassenti, Thomas J. Kipps, Susan L. Slager, Neil E. Kay, Connie Lesnick, Tait D. Shanafelt, Paolo Ghia, Lydia Scarfò, Kenneth J. Livak, Peter V. Kharchenko, Donna S. Neuberg, Lars Rønn Olsen, Jean Fan, Satyen H. Gohil, Catherine J. Wu
Journal: Blood
Blood (2022) 139 (14): 2252–2256.
https://doi.org/10.1182/blood.2021013926
Published: 2022
Includes: Supplemental data
Journal Articles

Single Cell Transcriptomic Characterization of the Immune Microenvironment in Naturally Progressing Chronic Lymphocytic Leukemia (CLL)

Noelia Purroy, MD PhD, Jean Fan, PhD, Shuqiang Li, Laura Z. Rassenti, PhD, James A Lederer, PhD, Donna S Neuberg, ScD, Thomas J. Kipps, MD PhD, Peter Kharchenko, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3112.
https://doi.org/10.1182/blood-2018-99-110931
Published: 2018
Journal Articles

Genetic and Transcriptomic Characterization of Marrow Progenitor Cells in Patients with Chronic Lymphocytic Leukemia

Lili Wang, MD PhD, Jean Fan, BS, Shuqiang Li, PhD, Jing Sun, PhD, Zachary Cartun, BS, Sarah Hegert, Rutendo Gambe, Stacey Fernandes, Rahul Satija, Donna S. Neuberg, ScD, Kenneth Livak, Adrian Wiestner, MD, Jennifer R. Brown, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2987.
https://doi.org/10.1182/blood.V130.Suppl_1.2987.2987
Published: 2017
Journal Articles

Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function

Lili Wang, MD PhD, Rutendo Gambe, BS, Jean Fan, BS, Youzhong Wan, PhD, Angela N Brooks, PhD, Jing Sun, PhD, Esther A. Obeng, MD PhD, Donna S Neuberg, ScD, Matthew Meyerson, MD PhD, Mark D. Fleming, MD DPhil, Benjamin L. Ebert, MD, Ruben D. Carrasco, MD PhD, Catherine J Wu, MD
Journal: Blood
Blood (2015) 126 (23): 366.
https://doi.org/10.1182/blood.V126.23.366.366
Published: 2015
Journal Articles

Comprehensive Bulk and Single Cell Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia

Jean Fan, BS, Lili Wang, MD PhD, Angela N Brooks, PhD, Youzhong Wan, PhD, Donna S Neuberg, ScD, Laura Z. Rassenti, PhD, Emanuela M. Ghia, PhD, Thomas J. Kipps, MD, PhD, Jennifer R. Brown, MD PhD, Shuqiang Li, Kenneth J Livak, Matthew M. Meyerson, PhD, Peter V. Kharchenko, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2015) 126 (23): 2906.
https://doi.org/10.1182/blood.V126.23.2906.2906
Published: 2015
Journal Articles

Integrated Single-Cell Detection of Genotype and Phenotype in SF3B1-Mutated Chronic Lymphocytic Leukemia Cells

Lili Wang, MD PhD, Dylan Kotliar, BA, Jean Fan, Shuqiang Li, PhD, Jonna Grimsby, Dan A. Landau, MD PhD, Jennifer R. Brown, MD PhD, Niall Lennon, Donna Neuberg, ScD, Kenneth J Livak, Catherine J. Wu, MD
Journal: Blood
Blood (2014) 124 (21): 1943.
https://doi.org/10.1182/blood.V124.21.1943.1943
Published: 2014