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Beatriz Moiraghi
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Journal Articles

Long-Term Results from the Optic Trial: A Dose-Optimization Study of 3 Starting Doses of Ponatinib

Jorge Cortes, Michael Deininger, Elza Lomaia, Beatriz Moiraghi, Soledad Undurraga, Carolina Pavlovsky, Charles Chuah, Tomasz Sacha, Jeffrey H. Lipton, James McCloskey, Andreas Hochhaus, Philippe Rousselot, Gianantonio Rosti, Hugues de Lavallade, Anna Turkina, Lori Maness, Moshe Talpaz, Michael Mauro, Vickie Lu, Alexander Vorog, Jane F Apperley
Journal: Blood
Blood (2023) 142 (Supplement 1): 3164.
https://doi.org/10.1182/blood-2023-178790
Published: 2023
Journal Articles

Final Report: Somatic Mutations and HMGCLL1 Haplotype Are Not Associated with Molecular Relapse-Free Survival in Patients with Chronic Myeloid Leukemia Who Attempt Treatment-Free Remission

Maria Agustina Perusini, Katia Pagnano, Carolina Pavlovsky, Beatriz Moiraghi, Ana Varela, Michele Bianchini, Carmen Fava, Jiří Mayer, Daniela Žáčková, Anežka Kvetková, Tomáš Jurček, Ivana Ježíšková, Ana Beatriz Pascoal Lopes, Gislaine Borba Oliveira, Carmino De Souza, Amirthagowri Ambalavanan, Anthea Travas, Jaeyoon John Kim, Danielle Pyne, Jessie Medeiros, Sagi Abelson, Dennis Dong Hwan Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 4543.
https://doi.org/10.1182/blood-2023-189797
Published: 2023
Journal Articles

Long-Term Follow-up of the AST Trial of Treatment-Free Remission in Chronic Myeloid Leukemia Patients

Ricardo K Tannuri, Beatriz Moiraghi, Ana Varela, Michele Bianchini, Miguel Arturo Pavlovsky, Georgina Bendek Del Prete, Maria Rosario Custidiano, Maria Josefina Freitas, Veronica Ventriglia, Eduardo Bullorsky, Pedro Negri Aranguren, Isolda Isabel Fernandez, Federico Sackmann Massa, Ana Garcia Labanca, Romina Mariano, Maria Fernanda Tosin, Juan Carlos Dupont, Francisca Rojas, Carina Gumpel, Etelvina Macchiavelo, Mariano Paoletti, Isabel Giere, Mariana Juni, Bianca Vasconcelos, Maria Belen Sanchez, Julio Cesar Sanchez Avalos, María Jose Mela Osorio, Carolina Pavlovsky
Journal: Blood
Blood (2023) 142 (Supplement 1): 6365.
https://doi.org/10.1182/blood-2023-189393
Published: 2023
Journal Articles

Economic Impact Analysis of Treatment-Free Remission in Chronic Myeloid Leukemia Patients with Sustained Deep Molecular Response in the AST-2018 Trial

Ricardo Khalil Khalil Tannuri, Beatriz Moiraghi, Miguel Arturo Pavlovsky, Ana Ines Varela, Michele Bianchini, Isabel Giere, Isolda I. Fernandez, Georgina Bendek, Romina Mariano, Josefina Freitas, Veronica Ventriglia, Maria Del Rosario Custidiano, Ana Garcia de Labanca, Julio Cesar Sanchez Avalos, Maria J. Mela Osorio, Bianca Vasconcelos Cordoba, Maria Belen Sanchez, Mariana Juni, Marcos Bianco, Carolina Pavlovsky
Journal: Blood
Blood (2022) 140 (Supplement 1): 5088–5089.
https://doi.org/10.1182/blood-2022-162407
Published: 2022
Journal Articles

A Risk Model for CML Patients with COVID-19: Importance of Molecular Response in the Context of Age, Comorbidities and Country Income

Jerald P. Radich, Chung Hoow Kok, Ekaterina Yu. Chelysheva, Jorge E. Cortes, Qian Jiang, Michael Mauro, Dragana Milojkovic, Beatriz Moiraghi, Franck E. Nicolini, Matilda Ongondi, Katia B Pagnano, Daniela Žácková, Delphine Rea, Nicola Evans, Timothy Hughes
Journal: Blood
Blood (2022) 140 (Supplement 1): 9617–9619.
https://doi.org/10.1182/blood-2022-165855
Published: 2022
Journal Articles

The Prognostic Impact of HMGCLL1 Gene Variant on Treatment Outcomes in Chronic Myeloid Leukemia (CML) Patients: Adverse Impact on the Response, Failure, and Progression with Imatinib Which Can be Abrogated By the Use of 2 nd Generation Tyrosine Kinase Inhibitor (TKI) Upfront Therapy

Maria Agustina Perusini, Taehyung Simon Kim, Daniela Žácková, Katia B Pagnano, Jiří Mayer, Carolina Pavlovsky, Ivana Ježíšková, Anežka Kvetková, Tomáš Jurček, Beatriz Moiraghi, Ana Ines Varela, Michele Bianchini, Ana Beatriz Pascoal Lopes, Gislaine B O Duarte, Young Seok Yoo, Carmino Antonio Souza, Jessie Medeiros, Hye Won Lee, Kyoung Ha Kim, Seong Yoon Yi, Myung Hee Chang, Sagi Abelson, Dennis Dong Hwan Kim
Journal: Blood
Blood (2022) 140 (Supplement 1): 6774–6775.
https://doi.org/10.1182/blood-2022-168228
Published: 2022
Journal Articles

Molecular Response of ≤10% BCR::ABL1 IS Is Predictive of Positive Outcomes in Treatment-Resistant Patients with Chronic Phase Chronic Myeloid Leukemia (CP-CML) Treated with Ponatinib from the Phase 2 Optic Trial

Jane F. Apperley, Jorge E. Cortes, Elias Jabbour, Andreas Hochhaus, Timothy Hughes, Charles Chuah, Hugues de Lavallade, Michael W. Deininger, Jeffrey H. Lipton, Elza Lomaia, Lori Maness, Michael Mauro, James McCloskey, Beatriz Moiraghi, Carolina Pavlovsky, Christine Rojas, Philippe Rousselot, Tomasz Sacha, Moshe Talpaz, Anna Turkina, Maria Undurraga Sutton, Xiaowei Ren, Alexander Vorog, Gianantonio Rosti
Journal: Blood
Blood (2022) 140 (Supplement 1): 6760–6762.
https://doi.org/10.1182/blood-2022-157956
Published: 2022
Journal Articles

Three-Year Update from the Optic Trial: A Dose-Optimization Study of 3 Starting Doses of Ponatinib

Jorge E. Cortes, Michael W. Deininger, Elza Lomaia, Beatriz Moiraghi, Maria Undurraga Sutton, Carolina Pavlovsky, Charles Chuah, Tomasz Sacha, Jeffrey H. Lipton, James McCloskey, Andreas Hochhaus, Philippe Rousselot, Gianantonio Rosti, Hugues de Lavallade, Christine Rojas, Anna Turkina, Lori Maness, Moshe Talpaz, Michael Mauro, Vickie Lu, Alexander Vorog, Jane F. Apperley
Journal: Blood
Blood (2022) 140 (Supplement 1): 1495–1497.
https://doi.org/10.1182/blood-2022-157822
Published: 2022
Journal Articles

Somatic Mutations Are Frequently Detected in CML Patients before Treatment-Free Remission (TFR) Attempt with Tyrosine Kinase Inhibitor (TKI) Discontinuation but with Uncertain Predictive Value for Tfr Failure

Maria Agustina Perusini, Katia B Pagnano, Carolina Pavlovsky, Beatriz Moiraghi, Ana Ines Varela, Michele Bianchini, Jiří Mayer, Daniela Žácková, Anežka Kvetková, Tomáš Jurček, Ivana Ježíšková, Ana Beatriz Pascoal Lopes, Gislaine B O Duarte, Carmino Antonio Souza, Jessie J.F. Medeiros, Taehyung Simon Kim, Young Seok Yoo, Kyoung Ha Kim, Hye Won Lee, Myung Hee Chang, Seong Yoon Yi, Sagi Abelson, Dennis Kim
Journal: Blood
Blood (2022) 140 (Supplement 1): 6782–6783.
https://doi.org/10.1182/blood-2022-167927
Published: 2022
Journal Articles

Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial

Clinical Trials & Observations
Jorge Cortes, Jane Apperley, Elza Lomaia, Beatriz Moiraghi, Maria Undurraga Sutton, Carolina Pavlovsky, Charles Chuah, Tomasz Sacha, Jeffrey H. Lipton, Charles A. Schiffer, James McCloskey, Andreas Hochhaus, Philippe Rousselot, Gianantonio Rosti, Hugues de Lavallade, Anna Turkina, Christine Rojas, Christopher Kevin Arthur, Lori Maness, Moshe Talpaz, Michael Mauro, Tracey Hall, Vickie Lu, Shouryadeep Srivastava, Michael Deininger
Journal: Blood
Blood (2021) 138 (21): 2042–2050.
https://doi.org/10.1182/blood.2021012082
Published: 2021
Includes: Supplemental data
Journal Articles

Post Hoc Analysis of Responses to Ponatinib in Patients with Chronic-Phase Chronic Myeloid Leukemia (CP-CML) By Baseline BCR-ABL1 Level and Baseline Mutation Status in the Optic Trial

Michael W. Deininger, Jane F Apperley, Christopher Kevin Arthur, Charles Chuah, Andreas Hochhaus, Hugues De Lavallade, Jeffrey H. Lipton, Elza Lomaia, James K McCloskey, Lori J. Maness, Michael J. Mauro, Beatriz Moiraghi, Carolina Pavlovsky, Gianantonio Rosti, Philippe Rousselot, Soledad S. Undurraga, Vickie Lu, Alexander Vorog, Jorge E. Cortes
Journal: Blood
Blood (2021) 138 (Supplement 1): 307.
https://doi.org/10.1182/blood-2021-145995
Published: 2021
Journal Articles

COVID-19 in Patients with Chronic Myeloid Leukemia: Poor Outcomes for Patients with Comorbidities, Older Age, Advanced Phase Disease, and Those from Low-Income Countries: An Update of the Candid Study

Katia B Pagnano, Chung Hoow Kok, Michael J. Mauro, Jorge E. Cortes, Nicola Evans, Qian Jiang, Dragana Milojkovic, Beatriz Moiraghi, Franck E. Nicolini, Matilda Ongondi, Daniela Zackova, Delphine Rea, Timothy P. Hughes
Journal: Blood
Blood (2021) 138 (Supplement 1): 634.
https://doi.org/10.1182/blood-2021-150026
Published: 2021
Journal Articles

High Level of Successful TKI Discontinuation in Chronic Myeloid Leukemia (CML) Patients: Preliminary Results of AST-Argentina Stop Trial

Carolina Pavlovsky, Ana Ines Varela, MD, Isolda I. Fernandez, MD, Maria Belen Sanchez, Maria Del Rosario Custidiano, MD, Josefina Freitas, MD, Veronica Ventriglia, MD, Ana Garcia de Labanca, MD, Georgina Bendek, MD, Romina Mariano, MD, Estrella Levy, PhD, Masiel Vera, Isabel Giere, PhD, Bianca Vasconcelos Cordoba, María Jose Mela Osorio, MD, Miguel A. Pavlovsky, MD, Julio Cesar Sanchez Avalos, MD, Cecilia Foncouberta, MD, Mariana Juni, Ms, Maximiliano Riddick, Michele Bianchini, PhD, Beatriz Moiraghi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–5.
https://doi.org/10.1182/blood-2020-142416
Published: 2020
Journal Articles

Real World Efficacy Evaluation of Branded and Copy Imatinib in Chronic Myeloid Leukemia: A Retrospective Multicentric Study from Argentina

Ana Ines Varela, MD, Georgina Bendek, MD, Carolina Pavlovsky, Maria Josefina Freitas, MD, Veronica Ventriglia, MD, Alicia Enrico, MD, Maria Elisa Riva, MD, Mariel Ana Perez, MD, Romina Mariano, MD, Luis Beligoy, MD, Maria Pagani, Ricardo Khalil Tannuri, Irene Larripa, MD, Raquel Bengio, MD, Francisca Rojas, Dardo Riveros, MD, Mariana Raquel Debus, MD, Erica Franceschi, MD, Maria Victoria Osycka, Miguel A. Pavlovsky, MD, Beatriz Moiraghi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-137792
Published: 2020
Journal Articles

In Pursuit of Surrogate Markers for Treatment-Free Remission in Patients with Chronic Myeloid Leukemia from Argentina Stop Trial

Maria Belen Sanchez, Beatriz Moiraghi, MD, Ana Ines Varela, MD, Estrella Levy, PhD, Masiel Vera, Bianca Vasconcelos Cordoba, Isabel Giere, PhD, Josefina Freitas, MD, Veronica Ventriglia, MD, Maria Del Rosario Custidiano, MD, Ana Garcia de Labanca, MD, Georgina Bendek, MD, Romina Mariano, MD, María Jose Mela Osorio, MD, Mariana Juni, Ms, Maximiliano Riddick, Miguel A. Pavlovsky, MD, Maria Cecilia Foncuberta, MD, Jose Mordoh, MD, Isolda I. Fernandez, MD, Julio Cesar Sanchez Avalos, MD, Carolina Pavlovsky, Michele Bianchini, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24.
https://doi.org/10.1182/blood-2020-141067
Published: 2020
Journal Articles

ENESTop 5-Year Update: Durability of Treatment-Free Remission Following Second-Line Nilotinib and Exploratory Analysis of Molecular Response Regain after Nilotinib Re-Initiation in Patients with Chronic Myeloid Leukemia

Francois-Xavier Mahon, MD PhD, Nelma D Clementino, MD, Mikhail Fominykh, MD, Jeffrey H. Lipton, MD PhD, Anna G. Turkina, Prof., MD, Beatriz Moiraghi, MD, Franck E Nicolini, MDPhD, Naoto Takahashi, MD PhD, Tomasz Sacha, MDPhD, Dong-Wook Kim, MD, Rafik Fellague-Chebra, MD, Ranjan Tiwari, MSc, Catherine Bouard, Timothy P. Hughes, MDMBBS,FRACP,FRCPA
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-136250
Published: 2020
Journal Articles

Real World Data on Obstetric (OC) and Maternal Complications (MC) Occurring in a Cohort of Patients with Ph Negative Myeloproliferative Neoplasms (MPN): Argentinian Multicentric Study

Angeles Vicente, MD, Paula G. Heller, MD, Georgina Bendek, MD, Federico Sackmann, MD, Ana Ines Varela, MD, Miguel Castro Rios, MD, Ludmila Elhelou, MD, Verónica Vallejo, MD, Beatriz Moiraghi, MD, Marina Narbaitz, MD, Anahí Vijnovich Baron, MD, Eriberto Roveri, MD, Claudia Casali, MD, Carlos Ponzinibio, MD, Marcelo Iastrebner, MD, María Susana Gomez, MD, Celeste Garcia, MD, Federico Sebastian Peretz, PhD, Paula Cardenas, MD, Alicia Enrico, MD, Guillermina Remaggi, MD, Santiago Boughen, MD, Irene Larripa, MD, Emiliano Carricondo, MD, Vanesa Caruso, MD, Mariel Perez, MD, Laura Kornblihtt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1669.
https://doi.org/10.1182/blood-2019-131778
Published: 2019
Journal Articles

Long-Term Efficacy and Safety (5 Years) in RESPONSE, a Phase 3 Study Comparing Ruxolitinib (rux) with Best Available Therapy (BAT) in Hydroxyurea (HU)-Resistant/Intolerant Patients (pts) with Polycythemia Vera (PV)

Jean-Jacques Kiladjian, MD PhD, Pierre Zachée, Masayuki Hino, MDPhD, Fabrizio Pane, Tamas Masszi, MD Prof., Claire N. Harrison, MD DM, FRCP, PRCPath, Ruben A. Mesa, MD, Carole B. Miller, MD, Francesco Passamonti, MD, Simon Durrant, FRCP,FRCPath,MBBS, Martin Griesshammer, MD PhD, Keita Kirito, MD, Carles Besses, MD PhD, Beatriz Moiraghi, Elisa Rumi, MD, Vittorio Rosti, MD, Igor W. Blau, Nathalie Francillard, Tuochuan Dong, Monika Wroclawska, MD, Alessandro M. Vannucchi, MD, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1753.
https://doi.org/10.1182/blood-2018-99-115129
Published: 2018
Journal Articles

"M3-M6" Molecular Response Evolution As Early Predictor of Outcome Considering Generic Vs Branded TKIs for Chronic Myeloid Leukemia (CML): An Argentine Multicentric Study

Isabel Amanda Giere, PhD M.Sc, María Jose Mela Osorio, MD, Federico Andrés Klosowski, Mariana Debus, Federico Sackmann, MD, Miguel A Pavlovsky, MD, Isolda Fernandez, MD, Elena Beatriz Moiraghi, MD, Ana Inés Varela, MD, Mariel Ana Perez, MD, Julio M. Pose Cabarcos, MD, Georgina Bendek, MD, Romina Mariano, MD, Silvina Palmer, MD, Alicia Enrico, MD, Isabel Cristina Annetta, MD, Andres L. Brodsky, MD PhD, Dante Intile, Statistic MD, Carolina Pavlovsky, MD
Journal: Blood
Blood (2016) 128 (22): 5445.
https://doi.org/10.1182/blood.V128.22.5445.5445
Published: 2016
Journal Articles

Patient-Reported Quality of Life before and after Stopping Treatment in the ENESTop Trial of Treatment-Free Remission for Patients with Chronic Myeloid Leukemia in Chronic Phase

François-Xavier Mahon, MD PhD, Carla Maria Boquimpani, Naoto Takahashi, MD PhD, Noam Benyamini, MD, Nelma Cristina D Clementino, MD, Vasily Shuvaev, MD, Sikander Ailawadhi, MD, Jeffrey H. Lipton, MD PhD, Anna G Turkina, Prof., MD, Elena Beatriz Moiraghi, MD, Franck-Emmanuel Nicolini, MD PhD, Jolanta Dengler, Tomasz Sacha, Dong-Wook Kim, MD PhD, Rafik Fellague-Chebra, MD MSc, Sandip Acharya, MSc, Patricia Brandt, Ari Gnanasakthy, MBA, MSc, Yu Jin, MS, Timothy P. Hughes, MD FRACP, FRCPA, MBBS, FAAHMS
Journal: Blood
Blood (2016) 128 (22): 1891.
https://doi.org/10.1182/blood.V128.22.1891.1891
Published: 2016