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Journal Articles

Molecular determinants of outcome in CLL patients treated on zanubrutinib registration trials

Inhye Ahn, Zunqiu Wang, Svitlana Tyekucheva, Kiyomi Mashima, Stacey Fernandes, Vanitha Ramakrishnan, Jessica Li, Linlin Xu, Rameen Beroukhim, Ignaty Leshchiner, Jennifer Brown

Blood (2025) 146 (Supplement 1): 2113.

https://doi.org/10.1182/blood-2025-2113

Published: 2025

Journal Articles

Multi-proteomic analyses provide evidence for origin of a co-existing serum monoclonal gammopathy in CLL/MBL

Blood (2025) 146 (Supplement 1): 7408.

https://doi.org/10.1182/blood-2025-7408

Published: 2025

Journal Articles

SF3B1 mutations are associated with shorter time to first treatment in chronic lymphocytic leukemia

Fernanda Santos Azevedo, Kiyomi Mashima, Ava Bidgoli, Paulina Predko, Mariia Mikhaleva, Stephen Martindale, Stacey Fernandes, Svitlana Tyekucheva, Inhye Ahn, Matthew S Davids, Jennifer Brown

Blood (2025) 146 (Supplement 1): 3906.

https://doi.org/10.1182/blood-2025-3906

Published: 2025

Journal Articles

Characterization of IGHV subgroups and their prognostic relevance in CLL

Daniel Sungchul Choi, Uday Aditya Sarkar, Yue Ren, Yinglu Zhou, Roberta S. Azevedo, James Yoon, Kiyomi Mashima, Fernanda Santos Azevedo, Gordon Saksena, Stacey Fernandes, Paulina Predko, Matthew S Davids, Svitlana Tyekucheva, Jennifer Brown, Inhye Ahn

Blood (2025) 146 (Supplement 1): 3899.

https://doi.org/10.1182/blood-2025-3899

Published: 2025

Journal Articles

Clonal Evolution during Dual B Cell Receptor Pathway Inhibitor Therapy with Acalabrutinib and Umbralisib in CLL Patients

Saurabh Yadav, Sumbul Jawed Khan, Binu Kandathilparambil Sasi, Elizabeth F. Cohen, Kiyomi Mashima, Hannah Cormier, Stacey M. Fernandes, Samantha J. Shupe, Roberta Santos Azevedo, Mariia Mikhaleva, Philippe Armand, David C. Fisher, Matthew S. Davids, Inhye E. Ahn, Michael Y. Tolstorukov, Mark A. Murakami, Jennifer R. Brown

Blood (2024) 144 (Supplement 1): 4611.

https://doi.org/10.1182/blood-2024-207527

Published: 2024

Journal Articles

Low Variant Allele Frequency (VAF) TP53 Mutation (mut) Is Not a Poor Prognostic Marker in CLL Patients Treated with Targeted Therapy

Daniel Sungchul Choi, Yue Ren, Svitlana Tyekucheva, Stacey M. Fernandes, Mariia Mikhaleva, Kiyomi Mashima, Rayan Fardoun, Samantha J. Shupe, Stephen Martindale, Matthew S. Davids, Jennifer R. Brown, Inhye E. Ahn

Blood (2024) 144 (Supplement 1): 587.

https://doi.org/10.1182/blood-2024-208951

Published: 2024

Journal Articles

Complex Karyotype, but Not Isolated TP53 mutation, Predicts Overall Survival in Chronic Lymphocytic Leukemia Patients in the Era of Targeted Therapy

Roberta Santos Azevedo, Mariia Mikhaleva, Kiyomi Mashima, Stephen Martindale, Stacey M. Fernandes, Svitlana Tyekucheva, Inhye E. Ahn, Matthew S. Davids, Jennifer R. Brown

Blood (2024) 144 (Supplement 1): 583.

https://doi.org/10.1182/blood-2024-206576

Published: 2024

Journal Articles

Higher Mutational Burden Is an Independent Predictor of Shorter Time to First Treatment in Untreated Chronic Lymphocytic Leukemia Patients

Mariia Mikhaleva, Svitlana Tyekucheva, Kiyomi Mashima, Stacey M Fernandes, Matthew S Davids, Jennifer R. Brown

Blood (2023) 142 (Supplement 1): 3270.

https://doi.org/10.1182/blood-2023-173738

Published: 2023

Journal Articles

Investigating the Influence of Germline ATM Variants on Susceptibility to Chronic Lymphocytic Leukemia and Other Malignancies

Roberta Santos Azevedo, Francesca Morelli, Kiyomi Mashima, Rayan Fardoun, Svitlana Tyekucheva, Stacey M Fernandes, Samantha J. Shupe, Marissa Terra, Anisha Patel, Joseph Yu, Jennifer R. Brown

Blood (2023) 142 (Supplement 1): 3266.

https://doi.org/10.1182/blood-2023-180136

Published: 2023

Journal Articles

Characterizing ATM Aberrations in Chronic Lymphocytic Leukemia (CLL): Prognostic Implications and Sensitivity to PARP Inhibition

Kiyomi Mashima, Mariia Mikhaleva, Stacey M Fernandes, Samantha J. Shupe, Svitlana Tyekucheva, Matthew S. Davids, Jennifer R. Brown

Blood (2023) 142 (Supplement 1): 6507.

https://doi.org/10.1182/blood-2023-187406

Published: 2023

Journal Articles

Characteristics of Rare Germline ATM Variants in Chronic Lymphocytic Leukemia (CLL)

Kiyomi Mashima, Benjamin L. Lampson, Aditi Gupta, Nicholas Moore, Anna Petrackova, Samantha J. Shupe, Stacey M. Fernandes, Amaro Taylor-Weiner, Riaz Gillani, Hoyin Chu, Seunghun Han, Sabrina Camp, Eric Kofman, Gad Getz, Catherine J. Wu, Eliezer Van Allen, Saud H AlDubayan, Jennifer R. Brown

Blood (2022) 140 (Supplement 1): 9853–9854.

https://doi.org/10.1182/blood-2022-167009

Published: 2022

Journal Articles

Dimethyl Fumarate Ameliorates Graft-Versus-Host Disease By Negatively Regulating Aerobic Glycolysis in Alloreactive T-Cells

Kiyomi Mashima, MDPhD, Kazuya Sato, MDPhD, Norihito Takayama, Junko Izawa, Takashi Ikeda, MD, Kento Umino, MD, Hirofumi Nakano, MD, Daisuke Minakata, MD, Kaoru Morita, MD PhD, Chihiro Yamamoto, MD PhD, Masahiro Ashizawa, MD, Kaoru Hatano, MD PhD, Iekuni Oh, MD PhD, Ken Ohmine, MDPhD, Shin-ichiro Fujiwara, MD PhD, Yoshinobu Kanda, MD PhD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-136229

Published: 2020

Journal Articles

Steep Neutrophil Recovery Following Unrelated Bone Marrow Transplantation Is a Major Risk Factor for the Development of Acute Graft-Vs-Host Disease

Takashi Nagayama, MD, Shin-ichiro Fujiwara, MD PhD, Hirotomo Nakashima, MD, Shinichiro Kawaguchi, MD, Shoko Ito, MD, Kiyomi Mashima, MD, Kento Umino, MD, Daisuke Minakata, MD, Hirofumi Nakano, MD, Ryoko Yamasaki, MD, Kaoru Morita, MD PhD, Chihiro Yamamoto, MD PhD, Masahiro Ashizawa, MD, Kaoru Hatano, MD PhD, Kazuya Sato, MD PhD, Iekuni Oh, MD PhD, Ken Ohmine, MD PhD, Kazuo Muroi, MD PhD, Yoshinobu Kanda, MD PhD

Blood (2019) 134 (Supplement_1): 5686.

https://doi.org/10.1182/blood-2019-122537

Published: 2019

Journal Articles

Comprehensive Analysis of Chemokines in Host Organs and Their Corresponding Receptors on Donor T-Cells in Xenogeneic Gvhd Model

Yasufumi Kawasaki, MD PhD, Kazuya Sato, MDPhD, Hirofumi Nakano, MD, Kiyomi Mashima, MD, Daisuke Minakata, MD, Ryoko Yamasaki, MD, Kaoru Morita, MD PhD, Masahiro Ashizawa, MD, Chihiro Yamamoto, MD PhD, Kaoru Hatano, MD PhD, Shin-ichiro Fujiwara, MD PhD, Iekuni Oh, MD PhD, Ken Ohmine, MD PhD, Kazuo Muroi, MD PhD, Yoshinobu Kanda, MD PhD

Blood (2018) 132 (Supplement 1): 5676.

https://doi.org/10.1182/blood-2018-99-111773

Published: 2018

Journal Articles

Alloantigen-Activated Human T-Cells Increase Extracellular Fatty Acid Uptake and Intracellular Lipid Metabolism during Xenogeneic Gvhd

Hirofumi Nakano, MD, Kazuya Sato, MD PhD, Hiroko Hayakawa, PhD, Kiyomi Mashima, MD, Daisuke Minakata, MD, Kaoru Morita, MD PhD, Ryoko Yamasaki, MD, Masahiro Ashizawa, MD, Chihiro Yamamoto, MD PhD, Kaoru Hatano, MD PhD, Shin-ichiro Fujiwara, MD PhD, Iekuni Oh, MD PhD, Ken Ohmine, MD PhD, Kazuo Muroi, MD PhD, Yoshinobu Kanda, MD PhD

Blood (2018) 132 (Supplement 1): 3320.

https://doi.org/10.1182/blood-2018-99-110011

Published: 2018

Journal Articles

Recipient Hematopoietic, but Not Non-Hematopoietic, Antigen-Presenting Cells Are Indispensable for CD4+ T-Cell-Mediated Xenogeneic Graft-Versus-Host Disease

Yasufumi Kawasaki, Kazuya Sato, MDPhD, Hiroko Hayakawa, PhD, Norihito Takayama, PhD, Hirofumi Nakano, MD, Kiyomi Mashima, MD, Daisuke Minakata, MD, Ryoko Yamasaki, MD, Kaoru Morita, MD PhD, Masahiro Ashizawa, MD, Chihiro Yamamoto, MD PhD, Kaoru Hatano, MD PhD, Shin-ichiro Fujiwara, MD PhD, Iekuni Oh, MD PhD, Ken Ohmine, MD PhD, Kazuo Muroi, MDPhD, Yoshinobu Kanda, MD PhD

Blood (2017) 130 (Supplement 1): 4441.

https://doi.org/10.1182/blood.V130.Suppl_1.4441.4441

Published: 2017

Journal Articles

Comprehensive Analysis of Activation and Proliferation Kinetics and Effector Functions of Human Lymphocyte Subsets in Xenogeneic GvHD Model

Blood (2016) 128 (22): 3350.

https://doi.org/10.1182/blood.V128.22.3350.3350

Published: 2016

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Molecular determinants of outcome in CLL patients treated on zanubrutinib registration trials

Multi-proteomic analyses provide evidence for origin of a co-existing serum monoclonal gammopathy in CLL/MBL

SF3B1 mutations are associated with shorter time to first treatment in chronic lymphocytic leukemia

Characterization of IGHV subgroups and their prognostic relevance in CLL

Clonal Evolution during Dual B Cell Receptor Pathway Inhibitor Therapy with Acalabrutinib and Umbralisib in CLL Patients

Low Variant Allele Frequency (VAF) TP53 Mutation (mut) Is Not a Poor Prognostic Marker in CLL Patients Treated with Targeted Therapy

Complex Karyotype, but Not Isolated TP53 mutation, Predicts Overall Survival in Chronic Lymphocytic Leukemia Patients in the Era of Targeted Therapy

Higher Mutational Burden Is an Independent Predictor of Shorter Time to First Treatment in Untreated Chronic Lymphocytic Leukemia Patients

Investigating the Influence of Germline ATM Variants on Susceptibility to Chronic Lymphocytic Leukemia and Other Malignancies

Characterizing ATM Aberrations in Chronic Lymphocytic Leukemia (CLL): Prognostic Implications and Sensitivity to PARP Inhibition

Characteristics of Rare Germline ATM Variants in Chronic Lymphocytic Leukemia (CLL)

Dimethyl Fumarate Ameliorates Graft-Versus-Host Disease By Negatively Regulating Aerobic Glycolysis in Alloreactive T-Cells

Steep Neutrophil Recovery Following Unrelated Bone Marrow Transplantation Is a Major Risk Factor for the Development of Acute Graft-Vs-Host Disease

Comprehensive Analysis of Chemokines in Host Organs and Their Corresponding Receptors on Donor T-Cells in Xenogeneic Gvhd Model

Alloantigen-Activated Human T-Cells Increase Extracellular Fatty Acid Uptake and Intracellular Lipid Metabolism during Xenogeneic Gvhd

Recipient Hematopoietic, but Not Non-Hematopoietic, Antigen-Presenting Cells Are Indispensable for CD4+ T-Cell-Mediated Xenogeneic Graft-Versus-Host Disease

Comprehensive Analysis of Activation and Proliferation Kinetics and Effector Functions of Human Lymphocyte Subsets in Xenogeneic GvHD Model

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