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Journal Articles

Hypersensitivity Reactions to Native E. coli L-Asparaginase in Children with Acute Lymphoblastic Leukemia May Vary By Treatment Schedule and Type of Glucocorticoid in Induction: Results of Trial ALL-BFM 2000

Blood (2022) 140 (Supplement 1): 11676–11678.

https://doi.org/10.1182/blood-2022-163142

Published: 2022

Journal Articles

Multi-Omics Profiling of JMML HSPCs Reveals Onco-Fetal Reprogramming and Identifies Novel Prognostic Biomarkers and Therapeutic Targets in High-Risk JMML

Blood (2022) 140 (Supplement 1): 8729–8730.

https://doi.org/10.1182/blood-2022-162224

Published: 2022

Journal Articles

Superior Overall Survival with Blinatumomab Versus Chemotherapy As Pre-Transplant Consolidation Treatment in Children with High-Risk First-Relapse B-Cell Precursor Acute Lymphoblastic Leukemia (B-ALL): Longer Follow-up (FU) of a Phase 3 Randomized Controlled Trial (RCT)

Blood (2021) 138 (Supplement 1): 1231.

https://doi.org/10.1182/blood-2021-145476

Published: 2021

Journal Articles

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-136294

Published: 2020

Journal Articles

DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation

Julia Meyer, PhD, Maximillian Schönung, Christian Flotho, MD PhD, Adam B. Olshen, PhD, Mark Hartmann, PhD, Christoph Plass, PhD, Yusuke Okuno, MD PhD, Yoshiyuki Takahashi, MD PhD, Norihiro Murakami, MD PhD, Manabu Wakamatsu, MD, Mignon L. Loh, MD, Charlotte M. Niemeyer, MD, Hideki Muramatsu, MD PhD, Daniel B. Lipka, MD, Elliot Stieglitz, MD

Blood (2019) 134 (Supplement_1): 1693.

https://doi.org/10.1182/blood-2019-131279

Published: 2019

Journal Articles

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

Mattias Hofmans, MD, Barbara Depreter, PhD PharmD, Tim Lammens, PhD, Helene Cave, PharmD, PhD, Christian Flotho, MD PhD, Henrik Hasle, Valerie de Haas, MD PhD, Charlotte M. Niemeyer, MD, Jan Stary, Prof., MD PhD, Pieter Van Vlierberghe, PhD, Jan Philippé, MD PhD, Barbara De Moerloose, MD PhD

Blood (2019) 134 (Supplement_1): 1701.

https://doi.org/10.1182/blood-2019-123715

Published: 2019

Journal Articles

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Pier Paolo Leoncini, PhD, Alessandro Domenico Silvestris, PhD, Patrizia Vitullo, PhD, Marco Zecca, MD, Christian Flotho, MD PhD, Charlotte M. Niemeyer, MD, Angela Gallo, PhD, Alice Bertaina, MD PhD, Franco Locatelli, MD PhD, Pietro Merli, MD

Blood (2019) 134 (Supplement_1): 4229.

https://doi.org/10.1182/blood-2019-129965

Published: 2019

Journal Articles

Juvenile myelomonocytic leukemia: who’s the driver at the wheel?

Charlotte M. Niemeyer, Christian Flotho

Blood (2019) 133 (10): 1060–1070.

https://doi.org/10.1182/blood-2018-11-844688

Published: 2019

Journal Articles

5-Azacytidine Is Effective for Targeting Leukemia-Initiating Cells in Juvenile Myelomonocytic Leukemia

Christopher Felix Krombholz, PhD, Lorena Gallego Villar, PhD, Pritam Kumar Panda, MSc, MS, BSc, Sushree Sangita Sahoo, MSc, Marcin W. Wlodarski, MD PhD, Daniel B. Lipka, Christoph Plass, Charlotte Niemeyer, MD, Miriam Erlacher, MD PhD, Christian Flotho

Blood (2018) 132 (Supplement 1): 4342.

https://doi.org/10.1182/blood-2018-99-116594

Published: 2018

Journal Articles

SAMD9 and SAMD9L Germline Disorders in Patients Enrolled in Studies of the European Working Group of MDS in Childhood (EWOG-MDS): Prevalence, Outcome, Phenotype and Functional Characterisation

Blood (2018) 132 (Supplement 1): 643.

https://doi.org/10.1182/blood-2018-99-118389

Published: 2018

Journal Articles

DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia: An International Collaborative Analysis and Development of a Common Diagnostic Platform

Maximilian Schoenung, Elliot Stieglitz, Hideki Muramatsu, MD PhD, Norihiro Murakami, MD, Mark Hartmann, Manuel Wiesenfarth, Yusuke Okuno, MD PhD, Adam B. Olshen, PhD, Christoph Plass, Mignon L. Loh, MD, Charlotte Niemeyer, MD, Christian Flotho, Daniel B. Lipka

Blood (2018) 132 (Supplement 1): 3093.

https://doi.org/10.1182/blood-2018-99-114918

Published: 2018

Journal Articles

Monosomy 7 As the Initial Hit Followed By Sequential Acquisition of SETBP1 and ASXL1 Driver Mutations in Childhood Myelodysplastic Syndromes

Victor Pastor Loyola, MSc, Pritam Kumar Panda, MSc, MS, BSc, Sushree Sangita Sahoo, MSc, Enikoe Amina Szvetnik, Emilia J. Kozyra, MSc, Rebecca K Voss, MD, Dirk Lebrecht, PhD, Julius Wehrle, MD, Miriam Erlacher, MD PhD, Jan Stary, MD PhD, Christian Flotho, Gudrun Göhring, MD, Brigitte Schlegelberger, MD PhD, Brigitte Strahm, PD Dr., Charlotte Niemeyer, MD, Marcin W. Wlodarski, MD PhD

Blood (2018) 132 (Supplement 1): 105.

https://doi.org/10.1182/blood-2018-99-118910

Published: 2018

Journal Articles

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Blood (2016) 127 (9): 1163–1172.

https://doi.org/10.1182/blood-2015-09-667808

Published: 2016

Includes: Supplemental data

Journal Articles

Epigenetic Changes Accompany Disordered Hemoglobin Regulation in Juvenile Myelomonocytic Leukemia

Silvia Fluhr, Christopher Felix Krombholz, Angelina Meier, Christoph Plass, Charlotte Niemeyer, Christian Flotho

Blood (2015) 126 (23): 438.

https://doi.org/10.1182/blood.V126.23.438.438

Published: 2015

Journal Articles

Microrna-150 Regulates STAT5b Levels in Juvenile Myelomonocytic Leukemia (JMML)

Pier Paolo Leoncini, PhD, Alice Bertaina, MDPhD, Dimitrios Papaioannou, MD, Christian Flotho, Riccardo Masetti, MD, Silvia Bresolin, PhD, Giuseppe Menna, MD, Nicola Santoro, Marco Zecca, MD, Giuseppe Basso, Prof, MD, Giovanni Nigita, PhD, Sara Pagotto, PhD, Katia D'Ovidio, PhD, Rossella Rota, Carlo M. Croce, MD, Charlotte Marie Niemeyer, Prof, MD, Franco Locatelli, MD PhD, Ramiro Garzon, MD

Blood (2015) 126 (23): 2851.

https://doi.org/10.1182/blood.V126.23.2851.2851

Published: 2015

Journal Articles

5-Azacytidine Reduces Leukemic Burden in a Xenograft Model of Juvenile Myelomonocytic Leukemia

Christopher Felix Krombholz, Angelina Meier, Konrad Aumann, Silvia Fluhr, Matthias Kollek, Daniel B Lipka, Christoph Plass, Tania Witte, Charlotte Niemeyer, Miriam Erlacher, Christian Flotho

Blood (2015) 126 (23): 1655.

https://doi.org/10.1182/blood.V126.23.1655.1655

Published: 2015

Journal Articles

Bridging to transplant with azacitidine in juvenile myelomonocytic leukemia: a retrospective analysis of the EWOG-MDS study group

Annamaria Cseh, Charlotte M. Niemeyer, Ayami Yoshimi, Michael Dworzak, Henrik Hasle, Marry M. van den Heuvel-Eibrink, Franco Locatelli, Riccardo Masetti, Markus Schmugge, Ute Groß-Wieltsch, Andrea Candás, Andreas E. Kulozik, Lale Olcay, Meinolf Suttorp, Ingrid Furlan, Brigitte Strahm, Christian Flotho

Blood (2015) 125 (14): 2311–2313.

https://doi.org/10.1182/blood-2015-01-619734

Published: 2015

Journal Articles

Tracing the development of acute myeloid leukemia in CBL syndrome

Blood (2014) 123 (12): 1883–1886.

https://doi.org/10.1182/blood-2013-10-533844

Published: 2014

Includes: Supplemental data

Journal Articles

JMML Revisited: Role Und Outcome of Hematopoietic Stem Cell Transplantation in Subtypes of Juvenile Myelomonocytic Leukemia (JMML)

Blood (2012) 120 (21): 955.

https://doi.org/10.1182/blood.V120.21.955.955

Published: 2012

Journal Articles

Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML

Blood (2012) 119 (11): e96–e99.

https://doi.org/10.1182/blood-2011-12-395087

Published: 2012

NARROW

Hypersensitivity Reactions to Native E. coli L-Asparaginase in Children with Acute Lymphoblastic Leukemia May Vary By Treatment Schedule and Type of Glucocorticoid in Induction: Results of Trial ALL-BFM 2000

Multi-Omics Profiling of JMML HSPCs Reveals Onco-Fetal Reprogramming and Identifies Novel Prognostic Biomarkers and Therapeutic Targets in High-Risk JMML

Superior Overall Survival with Blinatumomab Versus Chemotherapy As Pre-Transplant Consolidation Treatment in Children with High-Risk First-Relapse B-Cell Precursor Acute Lymphoblastic Leukemia (B-ALL): Longer Follow-up (FU) of a Phase 3 Randomized Controlled Trial (RCT)

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Juvenile myelomonocytic leukemia: who’s the driver at the wheel?

5-Azacytidine Is Effective for Targeting Leukemia-Initiating Cells in Juvenile Myelomonocytic Leukemia

SAMD9 and SAMD9L Germline Disorders in Patients Enrolled in Studies of the European Working Group of MDS in Childhood (EWOG-MDS): Prevalence, Outcome, Phenotype and Functional Characterisation

DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia: An International Collaborative Analysis and Development of a Common Diagnostic Platform

Monosomy 7 As the Initial Hit Followed By Sequential Acquisition of SETBP1 and ASXL1 Driver Mutations in Childhood Myelodysplastic Syndromes

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Epigenetic Changes Accompany Disordered Hemoglobin Regulation in Juvenile Myelomonocytic Leukemia

Microrna-150 Regulates STAT5b Levels in Juvenile Myelomonocytic Leukemia (JMML)

5-Azacytidine Reduces Leukemic Burden in a Xenograft Model of Juvenile Myelomonocytic Leukemia

Bridging to transplant with azacitidine in juvenile myelomonocytic leukemia: a retrospective analysis of the EWOG-MDS study group

Tracing the development of acute myeloid leukemia in CBL syndrome

JMML Revisited: Role Und Outcome of Hematopoietic Stem Cell Transplantation in Subtypes of Juvenile Myelomonocytic Leukemia (JMML)

Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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