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Journal Articles

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Henrike Salié, Dimitrios Athanassopoulos, Lukas Braun, Dominik Schmidt, Viktor Fetsch, Rebeka N. Javorniczky, Jenny N.H.G Ho, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R Blazar, Eva-Maria Wagner Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp Tobias Meyer, Joachim Brumberg, Andreas Mackensen, Michael von Bergwelt-Baildon, Roland Coras, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Natalie Koehler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser

Blood (2023) 142 (Supplement 1): 100.

https://doi.org/10.1182/blood-2023-184867

Published: 2023

Journal Articles

Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms

Blood (2023) 141 (23): 2824–2840.

https://doi.org/10.1182/blood.2022015653

Published: 2023

Includes: Supplemental data

Journal Articles

Effective and Safe Immune Checkpoint Blockade Induces Complete Responses in Murine PTCL Model of ALCL

Linda Gräßel, Teresa Poggio, Geoffroy Andrieux, Irene Gonzalez-Menendez, Stefanie Kreutmair, Cornelius Miething, Federico Bonofiglio, Ivonne Aidee Montes Mojarro, Marie Follo, Dietmar Pfeifer, Falko Fend, Leticia Quintanilla-Martinez, Robert Zeiser, Suzanne Turner, Melanie Börries, Justus Duyster, Anna Lena Illert

Blood (2022) 140 (Supplement 1): 6466–6467.

https://doi.org/10.1182/blood-2022-168777

Published: 2022

Journal Articles

Autonomous BCR Signaling and Genetic Aberrations in CLL-Phenotype Monoclonal B Lymphocytosis in Siblings of CLL Patients

Julieta H. Sepulveda Yanez, Edwin Quinten, Marvyn T. Koning, Janneke A. Eken, Dietmar Pfeifer, Ruben A.L. De Groen, Diego Alvarez Saravia, Andreas Agathangelidis, Cornelis A.M. van Bergen, Kostas Stamatopoulos, Joost S.P. Vermaat, Katja Zirlik, Marcelo Navarrete, Hassan Jumaa, Hendrik Veelken

Blood (2022) 140 (Supplement 1): 1526–1527.

https://doi.org/10.1182/blood-2022-169429

Published: 2022

Journal Articles

Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation

Blood (2022) 140 (10): 1167–1181.

https://doi.org/10.1182/blood.2022016082

Published: 2022

Includes: Supplemental data

Journal Articles

Randomized Phase II Study of All- Trans Retinoic Acid and Valproic Acid Added to Decitabine in Newly Diagnosed Elderly AML Patients (DECIDER trial): Predictive Impact of TP53 Status

Blood (2021) 138 (Supplement 1): 2380.

https://doi.org/10.1182/blood-2021-146468

Published: 2021

Journal Articles

First-in-Human Study of WT1 Recombinant Protein Vaccination in Elderly Patients with AML in Remission: A Single-Center Experience

Stefanie Kreutmair, Dietmar Pfeifer, Miguel Waterhouse, Konstanze Döhner, Anna Frey, Justus Duyster, Anna Lena Illert, Michael Schmitt, Michael Lübbert

Blood (2021) 138 (Supplement 1): 1278.

https://doi.org/10.1182/blood-2021-150082

Published: 2021

Journal Articles

Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans

Blood (2020) 136 (12): 1442–1455.

https://doi.org/10.1182/blood.2020005957

Published: 2020

Includes: Supplemental data

Journal Articles

Integrative Study of EZH2 Mutational Status, Copy Number, Protein Expression and H3K27 Trimethylation in AML/MDS Patients

Julia Stomper, Ruth Meier, Tobias Ma, Dietmar Pfeifer, Annette Schmitt-Graeff, Michael Lübbert

Blood (2019) 134 (Supplement_1): 1422.

https://doi.org/10.1182/blood-2019-128231

Published: 2019

Journal Articles

Examining the Role of CD30 in an Anaplastic Large Cell Lymphoma Mouse Model

Teresa Poggio, Linda Graessel, Stefanie Kreutmair, Cornelius Miething, Dietmar Pfeifer, Geoffroy Andrieux, Melanie Boerries, Marie Follo, Suzanne Turner, Robert Zeiser, MD, Justus Duyster, MD, Anna Lena Illert

Blood (2019) 134 (Supplement_1): 2542.

https://doi.org/10.1182/blood-2019-125589

Published: 2019

Journal Articles

The Fanconi Anemia-Associated Protein NIPA Is Essential for the Nuclear Abundance of FANCD2

Blood (2019) 134 (Supplement_1): 3741.

https://doi.org/10.1182/blood-2019-125973

Published: 2019

Journal Articles

In Vivo Kinetics of Early, Hypomethylating Agent-Induced Methylome and Transcriptome Changes in Primary AML Blasts: Random or Specific?

Gabriele Greve, Geoffroy Andrieux, Pascal Schlosser, Nadja Blagitko-Dorfs, Hans-Walter Lindemann, MD, Michael Heuser, MD, Andreas Neubauer, Jürgen Krauter, MD, Helmut R. Salih, MD, Gerhard Heil, Carsten Schwänen, Carsten Müller-Tidow, Arnold Ganser, MD, Hartmut Döhner, MD, Dietmar Pfeifer, Björn Hackanson, Olga Grishina, Melanie Boerries, Michael Lübbert

Blood (2018) 132 (Supplement 1): 3892.

https://doi.org/10.1182/blood-2018-99-118762

Published: 2018

Journal Articles

Metabolic Reprogramming Overcomes T Cell Inhibition By AML Cells

Franziska Maria Uhl, MSc, Sophia Chen, MD, David O'Sullivan, PhD, Michael Buck, PhD, Jörg Büscher, PhD, Dietmar Pfeifer, Jürgen Finke, MD, Justus Duyster, Prof., Hartmut Bertz, MD, Khalid Shoumariyeh, MD, Melanie Börries, PhD, Gesa Richter, MSc, Tobias Madl, PhD, Erika L. Pearce, PhD, Robert Zeiser, MD

Blood (2018) 132 (Supplement 1): 3328.

https://doi.org/10.1182/blood-2018-99-112897

Published: 2018

Journal Articles

Checkpoint Inhibition in CSF3R Mutated Chronic Neutrophilic Leukemia

Stefanie Kreutmair, MD, Teresa Poggio, Chuanjiang Yu, Sivahari Prasad Gorantla, Khalid Shoumariyeh, Dietmar Pfeifer, Michael Lubbert, MD PhD, Karsten Spiekermann, MD, Robert Zeiser, MD, Justus Duyster, Prof., Anna Lena Illert, MD

Blood (2018) 132 (Supplement 1): 3056.

https://doi.org/10.1182/blood-2018-99-113847

Published: 2018

Journal Articles

Preferential In Vitro and In Vivo Induction of Endogenous Retrovirus Transcription from a Monoallelic Chromosome 7q in Decitabine (DAC) Treated AML Blasts

Gabriele Greve, Dietmar Pfeifer, Sina Bengel, Michael Lübbert

Blood (2017) 130 (Supplement 1): 2612.

https://doi.org/10.1182/blood.V130.Suppl_1.2612.2612

Published: 2017

Journal Articles

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

Benjamin M. Matta, Dawn K. Reichenbach, Xiaoli Zhang, Lisa Mathews, Brent H. Koehn, Gaelen K. Dwyer, Jeremy M. Lott, Franziska M. Uhl, Dietmar Pfeifer, Colby J. Feser, Michelle J. Smith, Quan Liu, Robert Zeiser, Bruce R. Blazar, Hēth R. Turnquist

Blood (2016) 128 (3): 427–439.

https://doi.org/10.1182/blood-2015-12-684142

Published: 2016

Includes: Supplemental data

Journal Articles

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells

Blood (2016) 127 (15): 1930–1939.

https://doi.org/10.1182/blood-2015-09-672428

Published: 2016

Includes: Supplemental data

Journal Articles

Recipient Dendritic Cells Are Regulated By MiR-146a during Acute GvHD

Natalie Stickel, MSc, Kathrin Hanke, MSc, Martin Köhler, MSc, Gabriele Prinz, Dietmar Pfeifer, Annette Schmitt-Graeff, MD, Tilman Brummer, PhD, Juergen Finke, MD, Justus Duyster, MD PhD, Ulrich Salzer, MD, Robert Zeiser, MD

Blood (2015) 126 (23): 146.

https://doi.org/10.1182/blood.V126.23.146.146

Published: 2015

Journal Articles

Combination Treatment of AML Cells with Dnmt and HDAC Inhibitors: Synergistic Target Gene Downregulation Associated with Gene Body Demethylation

Nadja Blagitko-Dorfs, Pascal Schlosser, Dietmar Pfeifer, Michael Lübbert

Blood (2015) 126 (23): 2432.

https://doi.org/10.1182/blood.V126.23.2432.2432

Published: 2015

Journal Articles

Single Cell Genotyping of Inv(16) AML in CBL Mutated Clonal Hematopoiesis Characterizes Clonal Architecture and Evolution of Exome Sequencing-Identified Mutations in the Protein Tyrosine Phosphatase Ptprt and Other Genes

Christoph Niemöller, Sabine Bleul, Nadja Blagitko-Dorfs, PhD, Christine Greil, MD, Kenichi Yoshida, MD PhD, Rainer Claus, MD, Dietmar Pfeifer, PhD, Seishi Ogawa, MD PhD, Michael Lübbert, MD, Heiko Becker, MD

Blood (2015) 126 (23): 3834.

https://doi.org/10.1182/blood.V126.23.3834.3834

Published: 2015

NARROW

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms

Effective and Safe Immune Checkpoint Blockade Induces Complete Responses in Murine PTCL Model of ALCL

Autonomous BCR Signaling and Genetic Aberrations in CLL-Phenotype Monoclonal B Lymphocytosis in Siblings of CLL Patients

Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation

Randomized Phase II Study of All- Trans Retinoic Acid and Valproic Acid Added to Decitabine in Newly Diagnosed Elderly AML Patients (DECIDER trial): Predictive Impact of TP53 Status

First-in-Human Study of WT1 Recombinant Protein Vaccination in Elderly Patients with AML in Remission: A Single-Center Experience

Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans

Integrative Study of EZH2 Mutational Status, Copy Number, Protein Expression and H3K27 Trimethylation in AML/MDS Patients

Examining the Role of CD30 in an Anaplastic Large Cell Lymphoma Mouse Model

The Fanconi Anemia-Associated Protein NIPA Is Essential for the Nuclear Abundance of FANCD2

In Vivo Kinetics of Early, Hypomethylating Agent-Induced Methylome and Transcriptome Changes in Primary AML Blasts: Random or Specific?

Metabolic Reprogramming Overcomes T Cell Inhibition By AML Cells

Checkpoint Inhibition in CSF3R Mutated Chronic Neutrophilic Leukemia

Preferential In Vitro and In Vivo Induction of Endogenous Retrovirus Transcription from a Monoallelic Chromosome 7q in Decitabine (DAC) Treated AML Blasts

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells

Recipient Dendritic Cells Are Regulated By MiR-146a during Acute GvHD

Combination Treatment of AML Cells with Dnmt and HDAC Inhibitors: Synergistic Target Gene Downregulation Associated with Gene Body Demethylation

Single Cell Genotyping of Inv(16) AML in CBL Mutated Clonal Hematopoiesis Characterizes Clonal Architecture and Evolution of Exome Sequencing-Identified Mutations in the Protein Tyrosine Phosphatase Ptprt and Other Genes

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American Society of Hematology

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ASH Publications

American Society of Hematology

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