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Melanie Boerries
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Journal Articles

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Henrike Salié, Dimitrios Athanassopoulos, Lukas Braun, Dominik Schmidt, Viktor Fetsch, Rebeka N. Javorniczky, Jenny N.H.G Ho, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R Blazar, Eva-Maria Wagner Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp Tobias Meyer, Joachim Brumberg, Andreas Mackensen, Michael von Bergwelt-Baildon, Roland Coras, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Natalie Koehler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser
Journal: Blood
Blood (2023) 142 (Supplement 1): 100.
https://doi.org/10.1182/blood-2023-184867
Published: 2023
Journal Articles

CD49d Shapes B Cell Receptor Responsiveness and Tissue Distribution in an Aggressive Chronic Lymphocytic Leukemia Murine Model

Laura Polcik, Danielle-Justine Danner, Riccardo Bomben, Tamara Bittolo, Lixia Li, Driti Ashok, Sandra Kissel, Natalie Koehler, Andrea Härzschel, Geoffroy Andrieux, Melanie Boerries, Sophia Engel, Theresa Haslauer, Jan Hoepner, Nadja Zaborsky, Richard Greil, Cornelius Miething, Khalid Shoumariyeh, Jesus Duque Afonso, Justus Duyster, Antonella Zucchetto, Valter Gattei, Tanja Nicole Hartmann
Journal: Blood
Blood (2023) 142 (Supplement 1): 81.
https://doi.org/10.1182/blood-2023-179726
Published: 2023
Journal Articles

Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms

Amelie Jaeger, Sudheer Madan Mohan Gambheer, Xiaoyang Sun, Dmitry Chernyakov, Oleksandra Skorobohatko, Thomas Mack, Sandra Kissel, Dietmar Pfeifer, Robert Zeiser, Paul Fisch, Geoffroy Andrieux, Daniela Bräuer-Hartmann, Marcus Bauer, Susann Schulze, Marie Follo, Melanie Boerries, Nikolas von Bubnoff, Cornelius Miething, Jose Villacorta Hidalgo, Claudius Klein, Thomas Weber, Claudia Wickenhauser, Mascha Binder, Christine Dierks
Journal: Blood
Blood (2023) 141 (23): 2824–2840.
https://doi.org/10.1182/blood.2022015653
Published: 2023
Includes: Supplemental data
Journal Articles

Genetic and Epigenetic Changes at Secondary Resistance after Continued Treatment in the Randomized Phase II Study of All- Trans Retinoic Acid (ATRA) and/or Valproic Acid (VPA) Added to Decitabine (DAC) in Newly Diagnosed Elderly AML Patients (DECIDER Trial)

Inga Hund, Maria Hess, Julia Stomper, Gabriele Greve, Jan Mitschke, Christoph Niemöller, Tobias Ma, David Uhl, Felicitas R. Thol, Michael Heuser, Gesine Bug, Martina Crysandt, Lutz Peter Mueller, Andreas Neubauer, Justus Duyster, Hartmut Dohner, Melanie Boerries, Heiko Becker, Michael Luebbert
Journal: Blood
Blood (2022) 140 (Supplement 1): 3383–3384.
https://doi.org/10.1182/blood-2022-163220
Published: 2022
Journal Articles

Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation

Jenny N. H. G. Ho, Dominik Schmidt, Theresa Lowinus, Jeongmin Ryoo, Elaine-Pashupati Dopfer, Nicolás Gonzalo Núñez, Sara Costa-Pereira, Cristina Toffalori, Marco Punta, Viktor Fetsch, Tobias Wertheimer, Marie-Claire Rittmann, Lukas M. Braun, Marie Follo, Christelle Briere, Janaki Manoja Vinnakota, Marlene Langenbach, Felicitas Koppers, Khalid Shoumariyeh, Helena Engel, Tamina Rückert, Melanie Märklin, Samuel Holzmayer, Anna L. Illert, Federica Magon, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Julian Staniek, Marta Rizzi, Cornelius Miething, Natalie Köhler, Justus Duyster, Hans D. Menssen, Melanie Boerries, Joerg M. Buescher, Nina Cabezas-Wallscheid, Bruce R. Blazar, Petya Apostolova, Luca Vago, Erika L. Pearce, Burkhard Becher, Robert Zeiser
Journal: Blood
Blood (2022) 140 (10): 1167–1181.
https://doi.org/10.1182/blood.2022016082
Published: 2022
Includes: Supplemental data
Journal Articles

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue

Clinical Trials & Observations
Richa Sharma, Sushree S. Sahoo, Masayoshi Honda, Sophie L. Granger, Charnise Goodings, Louis Sanchez, Axel Künstner, Hauke Busch, Fabian Beier, Shondra M. Pruett-Miller, Marcus B. Valentine, Alfonso G. Fernandez, Ti-Cheng Chang, Vincent Géli, Dmitri Churikov, Sandrine Hirschi, Victor B. Pastor, Melanie Boerries, Melchior Lauten, Charikleia Kelaidi, Megan A. Cooper, Sarah Nicholas, Jill A. Rosenfeld, Sophia Polychronopoulou, Caroline Kannengiesser, Carole Saintomé, Charlotte M. Niemeyer, Patrick Revy, Marc S. Wold, Maria Spies, Miriam Erlacher, Stéphane Coulon, Marcin W. Wlodarski
Journal: Blood
Blood (2022) 139 (7): 1039–1051.
https://doi.org/10.1182/blood.2021011980
Published: 2022
Includes: Supplemental data
Journal Articles

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

Senthilkumar Ramamoorthy, PhD, Dirk Lebrecht, PhD, Denny Schanze, PhD, Ina Schanze, MD, Ilse Wieland, PhD, Michael H. Albert, MD, Arndt Borkhardt, MD, Dorine Bresters, MD PhD, Jochen Büchner, MDPhD, Albert Catala, MD PhD, Valerie De Haas, MD PhD, Michael Dworzak, MD PhD, Miriam Erlacher, MD PhD, Henrik Hasle, PhD, Kirsi Jahnukainen, MD PhD, Franco Locatelli, MD PhD, Riccardo Masetti, MDPhD, Jan Stary, MD PhD, Dominik Turkiewicz, MD, Luca Vinci, MD, Marcin W. Wlodarski, MD PhD, Ayami Yoshimi, MD PhD, Maria Hess, Melanie Boerries, MD PhD, Charlotte M. Niemeyer, MD, Martin Zenker, MD, Christian Flotho, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-136294
Published: 2020
Journal Articles

The Integrin Adaptor Kindlin-3 Is Important for Development and Retention of Marginal Zone B Cells

Andrea Härzschel, Peter William Krenn, Elisabeth Bayer, Simone Tangermann, Geoffroy Andrieux, Elif Karabatak, Eva Szenes, Danielle-Justine Danner, Ursula Denk, Raphael Ruppert, Alexander Egle, MD, Richard Greil, MD, Lukas Kenner, MD, Melanie Boerries, MD PhD, Tanja Nicole Hartmann, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–47.
https://doi.org/10.1182/blood-2020-136905
Published: 2020
Journal Articles

Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans

Johana Norona, Petya Apostolova, Dominik Schmidt, Rebekka Ihlemann, Nadine Reischmann, Gregory Taylor, Natalie Köhler, Jocelyn de Heer, Steffen Heeg, Geoffroy Andrieux, Benjamin A. Siranosian, Annette Schmitt-Graeff, Dietmar Pfeifer, Antonella Catalano, Ian J. Frew, Michele Proietti, Bodo Grimbacher, Alla Bulashevska, Ami S. Bhatt, Tilman Brummer, Till Clauditz, Tatjana Zabelina, Nicolaus Kroeger, Bruce R. Blazar, Melanie Boerries, Francis Ayuk, Robert Zeiser
Journal: Blood
Blood (2020) 136 (12): 1442–1455.
https://doi.org/10.1182/blood.2020005957
Published: 2020
Includes: Supplemental data
Journal Articles

The Fanconi Anemia-Associated Protein NIPA Is Essential for the Nuclear Abundance of FANCD2

Stefanie Kreutmair, Miriam Erlacher, Geoffroy Andrieux, Rouzanna Istvanffy, Alina Rudorf, Melissa Zwick, Tamina Rückert, Milena Pantic, Teresa Poggio, Khalid Shoumariyeh, MD, Tony Andreas Müller, Hiroyuki Kawaguchi, Marie Follo, Cathrin Klingeberg, Marcin Wlodarski, Irith Baumann, Dietmar Pfeifer, Michal Kulinski, Martina Rudelius, Simone Lemeer, Bernhard Kuster, Christine Dierks, Christian Peschel, Nina Cabezas-Wallscheid, Jesus Duque-Afonso, Robert Zeiser, MD, Michael Cleary, Detlev Schindler, Annette Schmitt-Graeff, Melanie Boerries, Charlotte M. Niemeyer, MD, Robert A.J. Oostendorp, Justus Duyster, MD, Anna Lena Illert
Journal: Blood
Blood (2019) 134 (Supplement_1): 3741.
https://doi.org/10.1182/blood-2019-125973
Published: 2019
Journal Articles

Examining the Role of CD30 in an Anaplastic Large Cell Lymphoma Mouse Model

Teresa Poggio, Linda Graessel, Stefanie Kreutmair, Cornelius Miething, Dietmar Pfeifer, Geoffroy Andrieux, Melanie Boerries, Marie Follo, Suzanne Turner, Robert Zeiser, MD, Justus Duyster, MD, Anna Lena Illert
Journal: Blood
Blood (2019) 134 (Supplement_1): 2542.
https://doi.org/10.1182/blood-2019-125589
Published: 2019
Journal Articles

In Vivo Kinetics of Early, Hypomethylating Agent-Induced Methylome and Transcriptome Changes in Primary AML Blasts: Random or Specific?

Gabriele Greve, Geoffroy Andrieux, Pascal Schlosser, Nadja Blagitko-Dorfs, Hans-Walter Lindemann, MD, Michael Heuser, MD, Andreas Neubauer, Jürgen Krauter, MD, Helmut R. Salih, MD, Gerhard Heil, Carsten Schwänen, Carsten Müller-Tidow, Arnold Ganser, MD, Hartmut Döhner, MD, Dietmar Pfeifer, Björn Hackanson, Olga Grishina, Melanie Boerries, Michael Lübbert
Journal: Blood
Blood (2018) 132 (Supplement 1): 3892.
https://doi.org/10.1182/blood-2018-99-118762
Published: 2018