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Melchior Lauten
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Journal Articles

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue

Clinical Trials & Observations
Richa Sharma, Sushree S. Sahoo, Masayoshi Honda, Sophie L. Granger, Charnise Goodings, Louis Sanchez, Axel Künstner, Hauke Busch, Fabian Beier, Shondra M. Pruett-Miller, Marcus B. Valentine, Alfonso G. Fernandez, Ti-Cheng Chang, Vincent Géli, Dmitri Churikov, Sandrine Hirschi, Victor B. Pastor, Melanie Boerries, Melchior Lauten, Charikleia Kelaidi, Megan A. Cooper, Sarah Nicholas, Jill A. Rosenfeld, Sophia Polychronopoulou, Caroline Kannengiesser, Carole Saintomé, Charlotte M. Niemeyer, Patrick Revy, Marc S. Wold, Maria Spies, Miriam Erlacher, Stéphane Coulon, Marcin W. Wlodarski
Journal: Blood
Blood (2022) 139 (7): 1039–1051.
https://doi.org/10.1182/blood.2021011980
Published: 2022
Includes: Supplemental data
Journal Articles

RPA1 Gain of Function Causes Human Short Telomere Syndrome with Revertant Somatic Mosaicism

Richa Sharma, MD, Sushree Sangita Sahoo, PhD, Masayoshi Honda, Charnise Goodings-Harris, PhD, Victor Pastor, PhD, Hauke Busch, PhD, Melanie Börries, PhD, Fabian Beier, MD, Miriam Erlacher, MD PhD, Melchior Lauten, Marc Wold, PhD, Maria Spies, PhD, Charlotte M. Niemeyer, MD, Marcin Wlodarski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-143006
Published: 2020
Journal Articles

Poor Prognosis in Children with ABL -Class Fusion Positive B-Cell Acute Lymphoblastic Leukemia Treated According to AIEOP-BFM Protocols

Gunnar Cario, MD PhD, Veronica Leoni, Valentino Conter, MD, Andishe Attarbaschi, MD, Marketa Zaliova, MD PhD, Lucie Sramkova, Giovanni Cazzaniga, PhD, Grazia Fazio, Rosemary Sutton, BSc MSc PhD, Sarah Elitzur, MD, Shai Izraeli, MD, Melchior Lauten, Franco Locatelli, MD PhD, Giuseppe Basso, MD PhD, Barbara Buldini, MD PhD, Anke K Bergmann, Jana Lentes, Doris Steinemann, Gudrun Gohring, Brigitte Schlegelberger, MD, Oskar A Haas, Denis Martin Schewe, Swantje Buchmann, Anja Moericke, Deborah L. White, PhD FFSc (RCPA), Tamas Revesz, Martin Stanulla, Georg Mann, MD, Nicole Bodmer, Nira Arad-Cohen, Jan Zuna, Maria Grazia Valsecchi, PhD, Martin Zimmermann, PhD, Martin Schrappe, MD PhD, Andrea Biondi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1351.
https://doi.org/10.1182/blood-2019-126523
Published: 2019
Journal Articles

Proteasome Inhibitor Bortezomib Induces Apoptosis in Prednisone-Resistant Childhood Acute Lymphoblastic Leukemia Cells.

Stefanie Junk, Melchior Lauten, MD, Gunnar Cario, MD, Nicole Wittner, Martin Schrappe, MD, Brigitte Schlegelberger, MD, Nils von Neuhoff, PhD
Journal: Blood
Blood (2009) 114 (22): 991.
https://doi.org/10.1182/blood.V114.22.991.991
Published: 2009
Journal Articles

Can Bortezomib Treatment Overcome Glucocorticoid Resistance of Childhood Acute Lymphoblastic Leukemia Cells?.

Stefanie V. Junk, Melchior Lauten, MD, Gunnar Cario, MD, Nicole Wittner, Martin Schrappe, MD, Brigitte Schlegelberger, MD, Nils von Neuhoff, PhD
Journal: Blood
Blood (2007) 110 (11): 2801.
https://doi.org/10.1182/blood.V110.11.2801.2801
Published: 2007
Journal Articles

Unsupervised Analysis of Human Leukemia Cells Identifies the Valosin-Containing Protein as a Putative Marker for Glucocorticoid Resistance.

Melchior Lauten, MD, Nils v. Neuhoff, PhD, Karl Welte, MD, PhD, Brigitte Schlegelberger, MD, PhD, Martin Schrappe, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 167.
https://doi.org/10.1182/blood.V104.11.167.167
Published: 2004