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Megan A. Cooper
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Journal Articles

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue

Clinical Trials & Observations
Richa Sharma, Sushree S. Sahoo, Masayoshi Honda, Sophie L. Granger, Charnise Goodings, Louis Sanchez, Axel Künstner, Hauke Busch, Fabian Beier, Shondra M. Pruett-Miller, Marcus B. Valentine, Alfonso G. Fernandez, Ti-Cheng Chang, Vincent Géli, Dmitri Churikov, Sandrine Hirschi, Victor B. Pastor, Melanie Boerries, Melchior Lauten, Charikleia Kelaidi, Megan A. Cooper, Sarah Nicholas, Jill A. Rosenfeld, Sophia Polychronopoulou, Caroline Kannengiesser, Carole Saintomé, Charlotte M. Niemeyer, Patrick Revy, Marc S. Wold, Maria Spies, Miriam Erlacher, Stéphane Coulon, Marcin W. Wlodarski
Journal: Blood
Blood (2022) 139 (7): 1039–1051.
https://doi.org/10.1182/blood.2021011980
Published: 2022
Includes: Supplemental data
Journal Articles

Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function

Jahnavi Aluri, Alicia Bach, Saara Kaviany, Luana Chiquetto Paracatu, Maleewan Kitcharoensakkul, Magdalena A. Walkiewicz, Christopher D. Putnam, Marwan Shinawi, Nermina Saucier, Elise M. Rizzi, Michael T. Harmon, Molly P. Keppel, Michelle Ritter, Morgan Similuk, Elaine Kulm, Michael Joyce, Adriana A. de Jesus, Raphaela Goldbach-Mansky, Yi-Shan Lee, Marina Cella, Peggy L. Kendall, Mary C. Dinauer, Jeffrey J. Bednarski, Christina Bemrich-Stolz, Scott W. Canna, Shirley M. Abraham, Matthew M. Demczko, Jonathan Powell, Stacie M. Jones, Amy M. Scurlock, Suk See De Ravin, Jack J. Bleesing, James A. Connelly, V. Koneti Rao, Laura G. Schuettpelz, Megan A. Cooper
Journal: Blood
Blood (2021) 137 (18): 2450–2462.
https://doi.org/10.1182/blood.2020009620
Published: 2021
Includes: Supplemental data
Journal Articles

Somatic mutations and clonal hematopoiesis in congenital neutropenia

Jun Xia, Christopher A. Miller, Jack Baty, Amrita Ramesh, Matthew R. M. Jotte, Robert S. Fulton, Tiphanie P. Vogel, Megan A. Cooper, Kelly J. Walkovich, Vahagn Makaryan, Audrey A. Bolyard, Mary C. Dinauer, David B. Wilson, Adrianna Vlachos, Kasiani C. Myers, Robert J. Rothbaum, Alison A. Bertuch, David C. Dale, Akiko Shimamura, Laurence A. Boxer, Daniel C. Link
Journal: Blood
Blood (2018) 131 (4): 408–416.
https://doi.org/10.1182/blood-2017-08-801985
Published: 2018
Includes: Supplemental data
Journal Articles

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Joshua D. Milner, Tiphanie P. Vogel, Lisa Forbes, Chi A. Ma, Asbjørg Stray-Pedersen, Julie E. Niemela, Jonathan J. Lyons, Karin R. Engelhardt, Yu Zhang, Nermina Topcagic, Elisha D. O. Roberson, Helen Matthews, James W. Verbsky, Trivikram Dasu, Alexander Vargas-Hernandez, Nidhy Varghese, Kenneth L. McClain, Lina B. Karam, Karen Nahmod, George Makedonas, Emily M. Mace, Hanne S. Sorte, Gøri Perminow, V. Koneti Rao, Michael P. O’Connell, Susan Price, Helen C. Su, Morgan Butrick, Joshua McElwee, Jason D. Hughes, Joseph Willet, David Swan, Yaobo Xu, Mauro Santibanez-Koref, Voytek Slowik, Darrell L. Dinwiddie, Christina E. Ciaccio, Carol J. Saunders, Seth Septer, Stephen F. Kingsmore, Andrew J. White, Andrew J. Cant, Sophie Hambleton, Megan A. Cooper
Journal: Blood
Blood (2015) 125 (4): 591–599.
https://doi.org/10.1182/blood-2014-09-602763
Published: 2015
Includes: Supplemental data
Journal Articles

Cytokine activation induces human memory-like NK cells

Rizwan Romee, Stephanie E. Schneider, Jeffrey W. Leong, Julie M. Chase, Catherine R. Keppel, Ryan P. Sullivan, Megan A. Cooper, Todd A. Fehniger
Journal: Blood
Blood (2012) 120 (24): 4751–4760.
https://doi.org/10.1182/blood-2012-04-419283
Published: 2012
Includes: Supplemental data
Journal Articles

CD56 bright natural killer cells are present in human lymph nodes and are activated by T cell–derived IL-2: a potential new link between adaptive and innate immunity

Todd A. Fehniger, Megan A. Cooper, Gerard J. Nuovo, Marina Cella, Fabio Facchetti, Marco Colonna, Michael A. Caligiuri
Journal: Blood
Blood (2003) 101 (8): 3052–3057.
https://doi.org/10.1182/blood-2002-09-2876
Published: 2003
Journal Articles

In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells

Megan A. Cooper, Jennifer E. Bush, Todd A. Fehniger, Jeffrey B. VanDeusen, Ross E. Waite, Yang Liu, Hector L. Aguila, Michael A. Caligiuri
Journal: Blood
Blood (2002) 100 (10): 3633–3638.
https://doi.org/10.1182/blood-2001-12-0293
Published: 2002
Journal Articles

Human natural killer cells: a unique innate immunoregulatory role for the CD56 bright subset

Megan A. Cooper, Todd A. Fehniger, Sarah C. Turner, Kenneth S. Chen, Bobak A. Ghaheri, Tariq Ghayur, William E. Carson, Michael A. Caligiuri
Journal: Blood
Blood (2001) 97 (10): 3146–3151.
https://doi.org/10.1182/blood.V97.10.3146
Published: 2001
Journal Articles

Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction

William E. Carson, Julie E. Dierksheide, Saad Jabbour, Mirela Anghelina, Page Bouchard, George Ku, Haixin Yu, Heinz Baumann, Manisha H. Shah, Megan A. Cooper, Joan Durbin, Michael A. Caligiuri
Journal: Blood
Blood (2000) 96 (4): 1465–1473.
https://doi.org/10.1182/blood.V96.4.1465
Published: 2000