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Journal Articles

Single-Center Experience of Decitabine/Venetoclax in Newly Diagnosed Older AML Patients with Non-Favorable Genetics: Bridging to Allo-HCT or Treatment Continuation

David Alber, Christoph Rummelt, Tim Strüßmann, Andrés Rettig, Valeria Shlyakhto, Paul La Rosée, Martin Henkes, Elizaveta Bubnova, Tobias Ma, Johanna Thomas, Gabriele Ihorst, Claudia Wehr, Reinhard Marks, Heiko Becker, Justus Duyster, Ralph Wäsch, Jürgen Finke, Michael Lübbert
Journal: Blood
Blood (2023) 142 (Supplement 1): 7091.
https://doi.org/10.1182/blood-2023-187581
Published: 2023
Journal Articles

Genetic and Epigenetic Changes at Secondary Resistance after Continued Treatment in the Randomized Phase II Study of All- Trans Retinoic Acid (ATRA) and/or Valproic Acid (VPA) Added to Decitabine (DAC) in Newly Diagnosed Elderly AML Patients (DECIDER Trial)

Inga Hund, Maria Hess, Julia Stomper, Gabriele Greve, Jan Mitschke, Christoph Niemöller, Tobias Ma, David Uhl, Felicitas R. Thol, Michael Heuser, Gesine Bug, Martina Crysandt, Lutz Peter Mueller, Andreas Neubauer, Justus Duyster, Hartmut Dohner, Melanie Boerries, Heiko Becker, Michael Luebbert
Journal: Blood
Blood (2022) 140 (Supplement 1): 3383–3384.
https://doi.org/10.1182/blood-2022-163220
Published: 2022
Journal Articles

Phase I Study of the LSD1 Inhibitor Tranylcypromine (TCP) in Combination with All- Trans Retinoic Acid (ATRA) and Low-Dose Cytarabine (LDAC) in Elderly, Medically Non-Fit Patients with AML or High-Risk MDS (TRANSATRA trial)

Michael Lübbert, Claudia Schmoor, Tobias Berg, Michael Kruszewski, Marcus Matthias Schittenhelm, Katharina Götze, Caroline Pabst, Andrea Kündgen, Tobias Ma, Anna Frey, Kevin Moschallski, Usama-Ur Rehman, Johannes Jung, Justus Duyster, Manfred Jung, Roland Schüle, Ralph Wäsch, Olga Grishina
Journal: Blood
Blood (2022) 140 (Supplement 1): 9087–9088.
https://doi.org/10.1182/blood-2022-159471
Published: 2022
Journal Articles

Genetic and Pharmacological Inhibition of BTK Increases Dasatinib Sensitivity in Vitro and In Vivo Including CNS-Infiltrating E2A-PBX1 + /Pre-BCR + ALL Cells

Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncarenko, Stefan Tholen, Kyuho Han, David Morgens, Marco Prinz, Michael Luebbert, Peter Bronsert, Michael Bassik, Michael Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque Afonso
Journal: Blood
Blood (2022) 140 (Supplement 1): 503–504.
https://doi.org/10.1182/blood-2022-162699
Published: 2022
Journal Articles

All- Trans retinoic Acid Enhances the Antileukemic Activity of Decitabine and Venetoclax in Non-M3 AML Cells

Helena Bresser, Usama-Ur Rehman, Julia Schüler, Anne Rubarth, Tobias Ma, Gabriele Greve, Heiko Becker, Michael Lübbert
Journal: Blood
Blood (2022) 140 (Supplement 1): 11537–11539.
https://doi.org/10.1182/blood-2022-167743
Published: 2022
Journal Articles

Integrative Study of EZH2 Mutational Status, Copy Number, Protein Expression and H3K27 Trimethylation in AML/MDS Patients

Julia Stomper, Ruth Meier, Tobias Ma, Dietmar Pfeifer, Annette Schmitt-Graeff, Michael Lübbert
Journal: Blood
Blood (2019) 134 (Supplement_1): 1422.
https://doi.org/10.1182/blood-2019-128231
Published: 2019
Journal Articles

Cooperative Effects of a Dnmt Inhibitor and All- Trans Retinoic Acid in an AML Cell Line Model Lacking PML-Rara

Ruth Meier, Gabriele Greve, Christoph Niemöller, Heiko Becker, Tobias Ma, Ralitsa Langova, Björn Grüning, Lars Feuerbach, Daniel B. Lipka, Justus Duyster, Prof., Benedikt Brors, Christoph Plass, Michael Lübbert
Journal: Blood
Blood (2018) 132 (Supplement 1): 1359.
https://doi.org/10.1182/blood-2018-99-113450
Published: 2018
Journal Articles

Identification of a Novel Chromosomal Translocation t(11;16)(q23;q22) Fusing MLL to Enhancer of mRNA Decapping (EDC)-4 in Smoldering Acute Myeloid Leukemia

Heiko Becker, MD, Keisuke Kataoka, MD PhD, Gabriele Greve, Jesús Duque Afonso, MD, Tobias Ma, Sabine Bleul, Milena Pantic, PhD, Julia Schüler, DVM, PhD, Justus Duyster, MD, Michael L Cleary, MD, Seishi Ogawa, MD PhD, Michael Lübbert, MD
Journal: Blood
Blood (2016) 128 (22): 1696.
https://doi.org/10.1182/blood.V128.22.1696.1696
Published: 2016
Journal Articles

In Vivo Methylome Changes in Purified Peripheral Blood Blasts and T Cells of AML Patients Treated with Decitabine: Statistical Modelling of a Hypomethylation Response

Nadja Blagitko-Dorfs, PhD, Pascal Schlosser, MSc, Rainer Claus, MD, Tobias Ma, M.Sc., Katharina Götze, Michael Heuser, MD, Gerhard Heil, MD, Sven Wessendorf, MD, Andreas Neubauer, MD, Jürgen Krauter, MD, Irmgard Dresel, MD, Konstanze Döhner, MD, Gesine Bug, Hans Walter Lindemann, MD, Helmut R. Salih, MD, Sebastian Scholl, MD, Carsten Mueller-Tidow, MD, Wolfram Brugger, MD, Olga Grishina, MD, Björn Hackanson, MD, Martin Schumacher, PhD, Michael Lübbert
Journal: Blood
Blood (2014) 124 (21): 870.
https://doi.org/10.1182/blood.V124.21.870.870
Published: 2014