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Journal Articles

The role of the MDM2/p53 axis in antitumor immune responses

Tilman Brummer, Robert Zeiser
Journal: Blood
Blood (2024) 143 (26): 2701–2709.
https://doi.org/10.1182/blood.2023020731
Published: 2024
Journal Articles

Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans

Johana Norona, Petya Apostolova, Dominik Schmidt, Rebekka Ihlemann, Nadine Reischmann, Gregory Taylor, Natalie Köhler, Jocelyn de Heer, Steffen Heeg, Geoffroy Andrieux, Benjamin A. Siranosian, Annette Schmitt-Graeff, Dietmar Pfeifer, Antonella Catalano, Ian J. Frew, Michele Proietti, Bodo Grimbacher, Alla Bulashevska, Ami S. Bhatt, Tilman Brummer, Till Clauditz, Tatjana Zabelina, Nicolaus Kroeger, Bruce R. Blazar, Melanie Boerries, Francis Ayuk, Robert Zeiser
Journal: Blood
Blood (2020) 136 (12): 1442–1455.
https://doi.org/10.1182/blood.2020005957
Published: 2020
Includes: Supplemental data
Journal Articles

Oncogenic KRAS G12D in the Hematopoietic System Causes NLRP3 Inflammasome Activation Leading to Myeloproliferative Syndrome

Shaima'A Hamarsheh, MSc, BSc, Miriam Erlacher, MD PhD, Lena Osswald, Oliver Gorka, PhD, Justus Duyster, Prof., Olaf Groß, PhD, Claudia Lengerke, MD, Melanie Börries, PhD, Tilman Brummer, PhD, Robert Zeiser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2618.
https://doi.org/10.1182/blood-2018-99-114161
Published: 2018
Journal Articles

Implementation of a Molecular Tumor Board in Clinical Decision Making at the Medical Center University of Freiburg

Rainer Claus, MD, Lisa Lutz, MD, Hauke Busch, PhD, Leman Mehmed, Agnes Csanadi, MD, Britta Weddeling, PhD, Ralph Fritsch, MD, Tilman Brummer, PhD, Julius Wehrle, MD, Cornelius Miething, MD, Thalia Erbes, MD, Simone Hettmer, MD, Volker Brass, MD, Oliver Oehlke, MD PhD, Philipp Demmer, MD, Frank Meiss, MD, Christoph Peters, MD, Martin Werner, MD, Melanie Börries, MD PhD, Silke Lassmann, PhD, Justus Duyster, MD, Nikolas von Bubnoff, MD
Journal: Blood
Blood (2016) 128 (22): 3579.
https://doi.org/10.1182/blood.V128.22.3579.3579
Published: 2016
Journal Articles

BRAF inhibition in hairy cell leukemia with low-dose vemurafenib

Clinical Trials & Observations
Sascha Dietrich, Andreas Pircher, Volker Endris, Frédéric Peyrade, Clemens-Martin Wendtner, George A. Follows, Jennifer Hüllein, Alexander Jethwa, Elena Ellert, Tatjana Walther, Xiyang Liu, Martin J. S. Dyer, Thomas Elter, Tilman Brummer, Robert Zeiser, Michael Hermann, Michael Herold, Wilko Weichert, Claire Dearden, Torsten Haferlach, Martina Seiffert, Michael Hallek, Christof von Kalle, Anthony D. Ho, Anita Gaehler, Mindaugas Andrulis, Michael Steurer, Thorsten Zenz
Journal: Blood
Blood (2016) 127 (23): 2847–2855.
https://doi.org/10.1182/blood-2015-11-680074
Published: 2016
Includes: Supplemental data
Journal Articles

Combined Inhibition of BCR and IGF1R Signaling Leads to Synergistic Apoptosis Induction in Primary CLL Cells in Vitro

Charlotte Schmidt-Salzmann, MD, Niuscha Yaktapour, PhD, Tilman Brummer, PhD, Katja Zirlik, MD, Rainer Claus, MD
Journal: Blood
Blood (2015) 126 (23): 4168.
https://doi.org/10.1182/blood.V126.23.4168.4168
Published: 2015
Journal Articles

Recipient Dendritic Cells Are Regulated By MiR-146a during Acute GvHD

Natalie Stickel, MSc, Kathrin Hanke, MSc, Martin Köhler, MSc, Gabriele Prinz, Dietmar Pfeifer, Annette Schmitt-Graeff, MD, Tilman Brummer, PhD, Juergen Finke, MD, Justus Duyster, MD PhD, Ulrich Salzer, MD, Robert Zeiser, MD
Journal: Blood
Blood (2015) 126 (23): 146.
https://doi.org/10.1182/blood.V126.23.146.146
Published: 2015
Journal Articles

Cooperative Activity of BRAF F595L and Mutant HRAS in Histiocytic Sarcoma Provides New Insights into Oncogenic BRAF Signaling

Maximilian Kordes, Michael Röring, Christoph Heining, Sandra Braun, Barbara Hutter, Daniela Richter, Christina Geörg, Claudia Scholl, Wilfried Roth, Andreas Rosenwald, MD, Eva Geissinger, Christof von Kalle, Dirk Jäger, Benedikt Brors, Wilko Weichert, Carsten Grüllich, Hanno Glimm, Tilman Brummer, PhD, Stefan Fröhling
Journal: Blood
Blood (2015) 126 (23): 1631.
https://doi.org/10.1182/blood.V126.23.1631.1631
Published: 2015
Journal Articles

Myelodysplastic Syndrome Caused By Activating Kras Mutation in the Non-Hematopoietic Bone Marrow Microenvironment

Lena Osswald, Cornelius Miething, MD, Justus Duyster, MD PhD, Tilman Brummer, PhD, Robert Zeiser, MD
Journal: Blood
Blood (2015) 126 (23): 359.
https://doi.org/10.1182/blood.V126.23.359.359
Published: 2015
Journal Articles

Combination Of Kinase Inhibitors Overcomes B-Raf Inhibitor-Induced Paradoxical ERK Activation In CLL Cells In Vitro – Potential Implications For CLL Treatment

Niuscha Yaktapour, Christine Dierks, Dietmar Pfeifer, Hassan Jumaa, Hendrik Veelken, MD PhD, Tilman Brummer, Katja Zirlik
Journal: Blood
Blood (2013) 122 (21): 4121.
https://doi.org/10.1182/blood.V122.21.4121.4121
Published: 2013
Journal Articles

Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia

Niuscha Yaktapour, Rudolf Übelhart, Julia Schüler, Konrad Aumann, Christine Dierks, Meike Burger, Dietmar Pfeifer, Hassan Jumaa, Hendrik Veelken, Tilman Brummer, Katja Zirlik
Journal: Blood
Blood (2013) 122 (9): 1621–1633.
https://doi.org/10.1182/blood-2013-02-484386
Published: 2013
Includes: Supplemental data
Journal Articles

IGF1R Inhibition Induces Apoptosis in Chronic Lymphocytic Leukemia

Niuscha Yaktapour, Rudolf Uebelhart, Christine Dierks, Meike Burger, Dietmar Pfeifer, Hassan Jumaa, Hendrik Veelken, MD PhD, Tilman Brummer, Katja Zirlik
Journal: Blood
Blood (2012) 120 (21): 3864.
https://doi.org/10.1182/blood.V120.21.3864.3864
Published: 2012