1-11 of 11
Roger Mulet-Lazaro
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Targeting Super-Enhancers Driving EVI1 Expression in Leukemia By Inhibition of p300/CBP

Dorien Pastoors, Claudia Erpelinck, Stanley Van Herk, Roger Mulet-Lazaro, Marije Havermans, Eric Bindels, Sophie Ottema, Ruud Delwel
Journal: Blood
Blood (2023) 142 (Supplement 1): 710.
https://doi.org/10.1182/blood-2023-181741
Published: 2023
Journal Articles

Cohesin-STAG2 Mutations Alter Chromatin Structure and Gene Regulation in Human Acute Myeloid Leukemia

Alexander Fischer, Roger Mulet-Lazaro, Margit Nützel, Stanley van Herk, Hanna Stanewsky, Ute Ackermann, Edith Reuschel, Nicholas Strieder, Inmaculada Hernandez-Lopez, Wolfgang Herr, Peter J.M. Valk, Michael Rehli, Ruud Delwel, Claudia Gebhard
Journal: Blood
Blood (2022) 140 (Supplement 1): 3379–3380.
https://doi.org/10.1182/blood-2022-162219
Published: 2022
Journal Articles

Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable EVI1-CtBP1/2 Interaction and By Repressing Myeloid Regulator CEBPA

Dorien Pastoors, Marije Havermans, Remco Hoogenboezem, Roger Mulet-Lazaro, Duncan Brian, Leonie Smeenk, Claudia Erpelinck-Verschueren, Stanley van Herk, Bas Wouters, Jeroen A.A. Demmers, Johannes Zuber, Tariq Enver, Richard WJ Groen, Eric Bindels, Ruud Delwel
Journal: Blood
Blood (2022) 140 (Supplement 1): 83–84.
https://doi.org/10.1182/blood-2022-156994
Published: 2022
Journal Articles

Aberrant EVI1 splicing contributes to EVI1 -rearranged leukemia

Atsushi Tanaka, Taizo A. Nakano, Masaki Nomura, Hiromi Yamazaki, Jan P. Bewersdorf, Roger Mulet-Lazaro, Simon Hogg, Bo Liu, Alex Penson, Akihiko Yokoyama, Weijia Zang, Marije Havermans, Miho Koizumi, Yasutaka Hayashi, Hana Cho, Akinori Kanai, Stanley C. Lee, Muran Xiao, Yui Koike, Yifan Zhang, Miki Fukumoto, Yumi Aoyama, Tsuyoshi Konuma, Hiroyoshi Kunimoto, Toshiya Inaba, Hideaki Nakajima, Hiroaki Honda, Hiroshi Kawamoto, Ruud Delwel, Omar Abdel-Wahab, Daichi Inoue
Journal: Blood
Blood (2022) 140 (8): 875–888.
https://doi.org/10.1182/blood.2021015325
Published: 2022
Includes: Supplemental data
Journal Articles

CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome

Clinical Trials & Observations
Franziska Taube, Julia Annabell Georgi, Michael Kramer, Sebastian Stasik, Jan Moritz Middeke, Christoph Röllig, Utz Krug, Alwin Krämer, Sebastian Scholl, Andreas Hochhaus, Tim H. Brümmendorf, Ralph Naumann, Andreas Petzold, Roger Mulet-Lazaro, Peter J. M. Valk, Björn Steffen, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan W. Krause, Mathias Hänel, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Sylvia Herold, Friedrich Stölzel, Katja Sockel, Malte von Bonin, Carsten Müller-Tidow, Uwe Platzbecker, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Christian Thiede, for the Study Alliance Leukemia (SAL)
Journal: Blood
Blood (2022) 139 (1): 87–103.
https://doi.org/10.1182/blood.2020009680
Published: 2022
Includes: Supplemental data
Journal Articles

The CBFβ-SMMHC/NRP1 Axis Regulates FLT3 and TGF-Beta Pathways in Inv(16) Acute Myeloid Leukemia

Mahesh Hegde, Mohd Hafiz Ahmad, Rui Li, Anneliese Carrascoso, Roger Mulet-Lazaro, Ruud Delwel, John H. Bushweller, Monica L. Guzman, Scot A. Wolfe, Julie Zhu, Lucio H. Castilla
Journal: Blood
Blood (2021) 138 (Supplement 1): 3314.
https://doi.org/10.1182/blood-2021-153275
Published: 2021
Journal Articles

Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML

Roger Mulet-Lazaro, Stanley van Herk, Claudia Erpelinck, Eric Bindels, Mathijs A. Sanders, Carlo Vermeulen, Ivo Renkens, Peter Valk, Ari M. Melnick, Jeroen de Ridder, Michael Rehli, Claudia Gebhard, Ruud Delwel, Bas J. Wouters
Journal: Blood
Blood (2021) 138 (2): 160–177.
https://doi.org/10.1182/blood.2020009244
Published: 2021
Includes: Supplemental data
Journal Articles

Atypical 3q26/ MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia

Sophie Ottema, Roger Mulet-Lazaro, H. Berna Beverloo, Claudia Erpelinck, Stanley van Herk, Robert van der Helm, Marije Havermans, Tim Grob, Peter J. M. Valk, Eric Bindels, Torsten Haferlach, Claudia Haferlach, Leonie Smeenk, Ruud Delwel
Journal: Blood
Blood (2020) 136 (2): 224–234.
https://doi.org/10.1182/blood.2019003701
Published: 2020
Includes: Supplemental data
Journal Articles

Allele-Specific Expression of GATA2 in AML with CEBPA Biallelic Mutations

Roger Mulet-Lazaro, MSc, Stanley van Herk, B.Sc., Claudia Erpelinck-Verschueren, B.Sc., Mathijs A. Sanders, PhD MSc, Eric Bindels, PhD, Peter Valk, PhD, Michael Rehli, PhD, Claudia Gebhard, PhD, Ruud Delwel, PhD, B.J. Wouters
Journal: Blood
Blood (2019) 134 (Supplement_1): 1235.
https://doi.org/10.1182/blood-2019-129766
Published: 2019
Journal Articles

Integrated Analysis of Global DNA Methylation and Transcription Reveals a Leukemia Subtype with Extreme Hypermethylation Associated with Silencing of Regulators of Differentiation

Claudia Gebhard, PhD, Roger Mulet-Lazaro, B.Sc., Lucia Schwarzfischer, Dagmar Glatz, Margit Nuetzel, Daniel Heudobler, MD, Sandra Pohl, Wolfgang Herr, MD, Gerhard Ehninger, MD, Claudia Erpelinck-Verschueren, B.Sc., Stanley van Herk, B.Sc., B.J. Wouters, Christian Thiede, MD, Ruud Delwel, PhD, Michael Rehli, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2608.
https://doi.org/10.1182/blood-2018-99-118521
Published: 2018
Journal Articles

Complex 3q26/EVI1 Rearrangements Genocopy Inv(3)/t(3;3) Acute Myeloid Leukemias By Enhancer Hijacking, EVI1 Overexpression, Absent MDS1-EVI1 and Low GATA2 Expression

Sophie Ottema, MSc, Roger Mulet-Lazaro, B.Sc., Berna Beverloo, PhD, Marije Havermans, Ir, Claudia Erpelinck-Verschueren, B.Sc., Tim Grob, MD, Peter Valk, PhD, Eric Bindels, PhD, Torsten Haferlach, MD, Claudia Haferlach, MD, Leonie Smeenk, PhD, Ruud Delwel, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2018-99-113339
Published: 2018