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Journal Articles

Id3 keeps the PD-1 checkpoint in check in GVHD

Chiara Bernardi, Federico Simonetta

Blood (2024) 143 (2): 103–104.

https://doi.org/10.1182/blood.2023022712

Published: 2024

Journal Articles

Hematopoietic Stem Cells Expressing Engineered CD45 Enable a Near Universal Targeted Therapy for Hematologic Diseases

Romina Marone, Simon Garaudé, Rosalba Lepore, Anna Devaux, Astrid Beerlage, Federico Simonetta, Anna Camus, Izabela Durzynska, Ian Kirby, Patrick Van Berkel, Christian Kunz, Stefanie Urlinger, Lukas T Jeker

Blood (2023) 142 (Supplement 1): 3418.

https://doi.org/10.1182/blood-2023-173706

Published: 2023

Journal Articles

A National Platform and Scoring System Allocates CAR-T Treatment Slots for Multiple Myeloma to Patients with High Likelihood of Complete Remission

Christoph Driessen, Katharina Baur, Dominik Heim, Sabine Gerull, Christoph Renner, Anne Cairoli, Thomas Pabst, Joerg Halter, Michael Gregor, Nicole Graf, Nino Fejzibegovic, Nathan Wolfensberger, Federico Simonetta, Martin Fehr, Esteban Ciliberti, Rouven Müller, Barbara Jeker

Blood (2023) 142 (Supplement 1): 4701.

https://doi.org/10.1182/blood-2023-182628

Published: 2023

Journal Articles

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Henrike Salié, Dimitrios Athanassopoulos, Lukas Braun, Dominik Schmidt, Viktor Fetsch, Rebeka N. Javorniczky, Jenny N.H.G Ho, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R Blazar, Eva-Maria Wagner Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp Tobias Meyer, Joachim Brumberg, Andreas Mackensen, Michael von Bergwelt-Baildon, Roland Coras, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Natalie Koehler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser

Blood (2023) 142 (Supplement 1): 100.

https://doi.org/10.1182/blood-2023-184867

Published: 2023

Journal Articles

Analysis of the T-cell repertoire and transcriptome identifies mechanisms of regulatory T-cell suppression of GVHD

Juliane K. Lohmeyer, Toshihito Hirai, Mustafa Turkoz, Stephane Buhler, Teresa Lopes Ramos, Natalie Köhler, Jeanette Baker, Astrid Melotti, Ingrid Wagner, Amandine Pradier, Sisi Wang, Xuhuai Ji, Simone Becattini, Jean Villard, Doron Merkler, Yves Chalandon, Robert S. Negrin, Federico Simonetta

Blood (2023) 141 (14): 1755–1767.

https://doi.org/10.1182/blood.2022017982

Published: 2023

Includes: Supplemental data

Journal Articles

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

Blood (2023) 141 (11): 1337–1352.

https://doi.org/10.1182/blood.2022018440

Published: 2023

Includes: Supplemental data

Journal Articles

PI3K and BTK Inhibition Induces the Upregulation of CD19 and Increases Sensitivity to CAR T Cells in a Model of Marginal Zone Lymphoma (MZL)

Sisi Wang, Alberto J Arribas, Chiara Tarantelli, Amandine Pradier, Lodovico Terzi Di Bergamo, Emanuele Zucca, Davide Rossi, Federico Simonetta, Francesco Bertoni

Blood (2022) 140 (Supplement 1): 4554–4555.

https://doi.org/10.1182/blood-2022-168625

Published: 2022

Journal Articles

T Cell Receptor Repertoire Profiling Reveals Breadth of Cellular Responses Against Sars-Cov-2 after Natural Infection and Vaccination in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Anne-Claire Mamez, Amandine Pradier, Caroline Stephan, Federica Giannotti, Stavroula Masouridi-Levrat, Sarah Morin, Dionysios Neofytos, Diem-Lan Vu, Astrid Melotti, Isabelle Arm-Vernez, Christiane S. Eberhardt, Jerome Tamburini, Laurent Kaiser, Yves Chalandon, Federico Simonetta

Blood (2022) 140 (Supplement 1): 10509–10511.

https://doi.org/10.1182/blood-2022-156983

Published: 2022

Journal Articles

Dual cytokine blockade in acute GVHD

Federico Simonetta

Blood (2021) 138 (24): 2453–2454.

https://doi.org/10.1182/blood.2021013772

Published: 2021

Journal Articles

Expansion of Phenotypically Senescent CD57+ CD8 T Cells Is Associated with Impaired Immunocompetence after Allogeneic Hematopoietic Stem Cell Transplantation

Sarah Morin, Amandine Pradier, Federica Giannotti, Anne-Claire Mamez, Diem-Lan Vu-Cantero, Marta Fabra-Urdiola, Caroline Stephan, Chiara Bernardi, Astrid Melotti, Stavroula Masouridi-Levrat, Eddy Roosnek, Laurent Kaiser, Yves Chalandon, Federico Simonetta

Blood (2021) 138 (Supplement 1): 1807.

https://doi.org/10.1182/blood-2021-153133

Published: 2021

Journal Articles

Invariant natural killer T-cell subsets have diverse graft-versus-host-disease–preventing and antitumor effects

Kristina Maas-Bauer, Juliane K. Lohmeyer, Toshihito Hirai, Teresa Lopes Ramos, Furqan M. Fazal, Ulrike M. Litzenburger, Kathryn E. Yost, Jessica V. Ribado, Neeraja Kambham, Arielle S. Wenokur, Po-Yu Lin, Maite Alvarez, Melissa Mavers, Jeanette Baker, Ami S. Bhatt, Howard Y. Chang, Federico Simonetta, Robert S. Negrin

Blood (2021) 138 (10): 858–870.

https://doi.org/10.1182/blood.2021010887

Published: 2021

Includes: Supplemental data

Journal Articles

RNA and TCR Sequencing Shed Light on Mechanisms of Treg Suppression in a Murine Model of Acute GvHD

Juliane K. Lohmeyer, MD, Toshihito Hirai, MD PhD, Mustafa Turkoz, PhD, Natalie Koehler, PhD, Jeanette Baker, Stephane Buhler, PhD, Jean Villard, MD PhD, Xuhuai Ji, MD PhD, Federico Simonetta, MD PhD, Robert S. Negrin, MD

Blood (2020) 136 (Supplement 1): 30.

https://doi.org/10.1182/blood-2020-137220

Published: 2020

Journal Articles

Real-Life Experience of Sorafenib Maintenance after Allogeneic Hematopoietic Stem Cell Transplantation for FLT3-ITD AML Reveals High Rates of Toxicity-Related Treatment Interruption

Sarah Morin, MD PhD, Federica Giannotti, MD, Anne-Claire Mamez, MD, Stavroula Masouridi-Levrat, MD, Federico Simonetta, MDPhD, Yves Chalandon, MD

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-138663

Published: 2020

Journal Articles

Impact of Different T Cell Depletion Protocols on Immune Reconstitution Following Allogeneic Hematopoietic Stem Cell Transplantation

Blood (2020) 136 (Supplement 1): 43–44.

https://doi.org/10.1182/blood-2020-139208

Published: 2020

Journal Articles

The AML EBMT Cytogenetic Risk Score for Acute Myeloid Leukaemia (AML) Is Prognostic for Outcomes of Allogeneic Stem Cell (HSCT)

Yan Beauverd, MD, Sarah Morin, MD PhD, Mitja Nabergoj, Caroline Stephan, Carmen De Ramon Ortiz, MD, Anne-Claire Mamez, MD, Elif Mahne, MD, Anna Petropoulou, MD, Federica Giannotti, MD, Federico Simonetta, MDPhD, Christian Ayer, MD, Benjamin Bruno, MD, Laura Bounaix, MD, Maria Anastasiou, MD, Maria Mappoura, MD, Thien-An Tran, MD, Stavroula Masouridi-Levrat, MD, Yves Chalandon, MD

Blood (2020) 136 (Supplement 1): 19–20.

https://doi.org/10.1182/blood-2020-140010

Published: 2020

Journal Articles

Molecular Imaging of Chimeric Antigen Receptor T Cells By ICOS-Immunopet

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-136331

Published: 2020

Journal Articles

Allogeneic Chimeric Antigen Receptor-Invariant Natural Killer T Cells Exert Both Direct and Indirect Antitumor Effects through Host CD8 T Cell Cross-Priming

Federico Simonetta, MD PhD, Toshihito Hirai, MD PhD, Juliane K. Lohmeyer, MD, Kristina Maas-Bauer, MD, Maite Alvarez, PhD, Arielle S. Wenokur, Jeanette Baker, Amin Aalipour, PhD, Samuel Haile, PhD, Crystal L. Mackall, MD, Robert S. Negrin, MD

Blood (2019) 134 (Supplement_1): 867.

https://doi.org/10.1182/blood-2019-122515

Published: 2019

Journal Articles

iNKT Cell Stimulation with Liposomal Alpha/Gal/Cer Amplifies Proliferation of Adoptively Transferred Regulatory T Cells In Vivo and Reduces GvHD

Toshihito Hirai, MD PhD, Federico Simonetta, MD PhD, Kristina Maas-Bauer, MD, Melissa Mavers, MD PhD, Jeanette Baker, Robert S. Negrin, MD

Blood (2018) 132 (Supplement 1): 4519.

https://doi.org/10.1182/blood-2018-99-109836

Published: 2018

Journal Articles

Tracking T Cell Activation By OX40 Immuno-PET: A Novel Strategy for Imaging of Graft Versus Host Disease

Federico Simonetta, MD PhD, Israt S. Alam, PhD, Aaron T. Mayer, Surya Murty, Ophir Vermesh, MD PhD, Toshihito Hirai, MD PhD, Tomomi Nobashi, MD, Kenneth Lau, Sanjiv S. Gambhir, MD PhD, Robert S. Negrin, MD

Blood (2018) 132 (Supplement 1): 4527.

https://doi.org/10.1182/blood-2018-99-116483

Published: 2018

Journal Articles

Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential

Kristina Maas-Bauer, MD, Federico Simonetta, MD PhD, Toshihito Hirai, MD PhD, Arielle Wenokur, Furqan Fazal, PhD, Neeraja Kambham, MD, Jessica Ribado, Melissa Mavers, MD PhD, Jeanette Baker, Ami S. Bhatt, MD PhD, Howard Y. Chang, MD PhD, Robert S. Negrin, MD

Blood (2018) 132 (Supplement 1): 475.

https://doi.org/10.1182/blood-2018-99-113673

Published: 2018

NARROW

Id3 keeps the PD-1 checkpoint in check in GVHD

Hematopoietic Stem Cells Expressing Engineered CD45 Enable a Near Universal Targeted Therapy for Hematologic Diseases

A National Platform and Scoring System Allocates CAR-T Treatment Slots for Multiple Myeloma to Patients with High Likelihood of Complete Remission

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Analysis of the T-cell repertoire and transcriptome identifies mechanisms of regulatory T-cell suppression of GVHD

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

PI3K and BTK Inhibition Induces the Upregulation of CD19 and Increases Sensitivity to CAR T Cells in a Model of Marginal Zone Lymphoma (MZL)

T Cell Receptor Repertoire Profiling Reveals Breadth of Cellular Responses Against Sars-Cov-2 after Natural Infection and Vaccination in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Dual cytokine blockade in acute GVHD

Expansion of Phenotypically Senescent CD57+ CD8 T Cells Is Associated with Impaired Immunocompetence after Allogeneic Hematopoietic Stem Cell Transplantation

Invariant natural killer T-cell subsets have diverse graft-versus-host-disease–preventing and antitumor effects

RNA and TCR Sequencing Shed Light on Mechanisms of Treg Suppression in a Murine Model of Acute GvHD

Real-Life Experience of Sorafenib Maintenance after Allogeneic Hematopoietic Stem Cell Transplantation for FLT3-ITD AML Reveals High Rates of Toxicity-Related Treatment Interruption

Impact of Different T Cell Depletion Protocols on Immune Reconstitution Following Allogeneic Hematopoietic Stem Cell Transplantation

The AML EBMT Cytogenetic Risk Score for Acute Myeloid Leukaemia (AML) Is Prognostic for Outcomes of Allogeneic Stem Cell (HSCT)

Molecular Imaging of Chimeric Antigen Receptor T Cells By ICOS-Immunopet

Allogeneic Chimeric Antigen Receptor-Invariant Natural Killer T Cells Exert Both Direct and Indirect Antitumor Effects through Host CD8 T Cell Cross-Priming

iNKT Cell Stimulation with Liposomal Alpha/Gal/Cer Amplifies Proliferation of Adoptively Transferred Regulatory T Cells In Vivo and Reduces GvHD

Tracking T Cell Activation By OX40 Immuno-PET: A Novel Strategy for Imaging of Graft Versus Host Disease

Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential

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American Society of Hematology

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ASH Publications

American Society of Hematology

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