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Journal Articles

Pre-Clinical Efficacy of the Novel Kinase Inhibitor Nintedanib on PAX5 Fusion Genes in Pediatric Ph-like B-Cell Precursor Acute Lymphoblastic Leukemia

Grazia Fazio, Silvia Bresolin, Claudia Saitta, Daniela Silvestri, Elena Vendramini, Chiara Palmi, Silvia Rigamonti, Marta Galbiati, Manuel Quadri, Stefano Mecca, Angela Maria Savino, Michela Bardini, Andrea Grioni, Maria Grazia Valsecchi, PhD, Geertruy te Kronnie, Andrea Biondi, MD, Giovanni Cazzaniga, PhD

Blood (2019) 134 (Supplement_1): 745.

https://doi.org/10.1182/blood-2019-128509

Published: 2019

Journal Articles

Bone Marrow Mesenchymal Stromal Cells and Inflammation Contribute to ETV6-RUNX1 + Preleukemic Cells Persistence and DNA Damaging

Linda Beneforti, Erica Dander, PhD, Silvia Bresolin, PhD, Clara Bueno, Geertruy te Kronnie, Anthony Ford, Pablo Menendez, Giovanna D'Amico, BSc, PhD MSc, Andrea Biondi, Chiara Palmi, Giovanni Cazzaniga, PhD

Blood (2018) 132 (Supplement 1): 3918.

https://doi.org/10.1182/blood-2018-99-114791

Published: 2018

Journal Articles

Activin A, a Potential Key Factor of the Malignant Bone Marrow Niche, Enhances B-Cell Precursor-Acute Lymphoblastic Leukemic Cell Migratory and Invasive Properties

Erica Dander, PhD, Federica Portale, PhD, Daniela Silvestri, Giulia Cricrì, Silvia Bresolin, PhD, Stefania Gaspari, Barbara Russo, Monica Lupi, Paolo Ubezio, Geertruy te Kronnie, Maria Grazia Valsecchi, PhD, Franco Locatelli, Carmelo Rizzari, MD, Andrea Biondi, MD, Giovanna D'Amico, BSc, PhD MSc

Blood (2018) 132 (Supplement 1): 1296.

https://doi.org/10.1182/blood-2018-99-116668

Published: 2018

Journal Articles

Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor

Vera Münch, Luca Trentin, Julia Herzig, Salih Demir, Felix Seyfried, Johann M. Kraus, Hans A. Kestler, Rolf Köhler, Thomas F. E. Barth, Geertruy te Kronnie, Klaus-Michael Debatin, Lüder H. Meyer

Blood (2017) 130 (5): 643–654.

https://doi.org/10.1182/blood-2017-03-769315

Published: 2017

Includes: Supplemental data

Journal Articles

TET1 Promotes Leukemic Growth in T-ALL Via Maintenance of 5-Hydroxymethylation Marks and Can be Antagonized By the PARP Inhibitor Olaparib

Deniz Sahin, M.Sc, Shiva Bamezai, PhD, Fabio Ciccarone, PhD, Elena Fischbein, MSc, Fabian Mohr, PhD, Medhanie A. Mulaw, Jun.-Prof. Dr., Alex Pulikkottil Jose, M.Sc, Paola Caiafa, MD, Lüder-Hinrich Meyer, MD, Klaus-Michael Debatin, Prof. Dr., Geertruy te Kronnie, PhD, Konstanze Döhner, Hartmut Döhner, Prof. Dr., Michaela Feuring-Buske, PD Dr., Christian Buske, Vijay P.S. Rawat, PhD

Blood (2016) 128 (22): 737.

https://doi.org/10.1182/blood.V128.22.737.737

Published: 2016

Journal Articles

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Blood (2016) 127 (9): 1163–1172.

https://doi.org/10.1182/blood-2015-09-667808

Published: 2016

Includes: Supplemental data

Journal Articles

Targeting Mutant p53 in Pediatric Acute Lymphoblastic Leukemia

Salih Demir, MSc, Galina Selivanova, PhD, Eugen Tausch, MD, Lisa Wiesmüller, PhD, Stephan Stilgenbauer, MDPhD, Geertruy Te Kronnie, PhD, Klaus-Michael Debatin, MDPhD, Lüder Hinrich Meyer, MD

Blood (2015) 126 (23): 903.

https://doi.org/10.1182/blood.V126.23.903.903

Published: 2015

Journal Articles

Migration of Acute Lymphoblastic Leukemia Cells into the Central Nervous System Is Regulated By VEGF

Vera Muench, Luca Trentin, PhD, Julia Herzig, Johann Krauss, Hans A Kestler, Geertruy te Kronnie, Klaus-Michael Debatin, MDPhD, Lueder Hinrich Meyer, MD

Blood (2015) 126 (23): 2634.

https://doi.org/10.1182/blood.V126.23.2634.2634

Published: 2015

Journal Articles

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Angela Maria Savino, Jolanda Sarno, Luca Trentin, Margherita Vieri, Grazia Fazio, PhD, Michela Bardini, Cristina Bugarin, Gianluca Fossati, Kara L. Davis, DO, Giuseppe Gaipa, PhD, Lueder Hinrich Meyer, MD, Garry P. Nolan, Prof, PhD, Andrea Biondi, Prof, MD, Geertruy Te Kronnie, PhD, Chiara Palmi, PhD, Giovanni Cazzaniga

Blood (2015) 126 (23): 2534.

https://doi.org/10.1182/blood.V126.23.2534.2534

Published: 2015

Journal Articles

Effective in Vivo Targeting of BCP-ALL in a NOD/SCID/huALL Mouse Model By CD70 Directed Immunotherapy

Qian Sun, PhD, Chiara Borga, PhD, Geertruy te Kronnie, PhD, Klaus-Michael Debatin, MDPhD, Lüder Hinrich Meyer, MD

Blood (2014) 124 (21): 970.

https://doi.org/10.1182/blood.V124.21.970.970

Published: 2014

Journal Articles

CRLF2 over-Expression Is a Poor Prognostic Marker in Children with High Risk T-Cell Acute Lymphoblastic Leukemia

Blood (2014) 124 (21): 1071.

https://doi.org/10.1182/blood.V124.21.1071.1071

Published: 2014

Journal Articles

The Strong Prognostic Effect of Concurrent Deletions of IKZF1 and PAX5 , CDKN2A , CDKN2B or PAR1 in the Absence of ERG Deletions (IKZF1 plus ) in Pediatric Acute Lymphoblastic Leukemia Strongly Depends on Minimal Residual Disease Burden after Induction Treatment

Blood (2014) 124 (21): 131.

https://doi.org/10.1182/blood.V124.21.131.131

Published: 2014

Journal Articles

Secondary Mutations of JAK3 and SETBP1 in Juvenile Myelomonocytic Leukemia and Their Propagating Capacity; A Report from the AIEOP Study Group

Silvia Bresolin, PhD, Paola De Filippi, Francesca Vendemini, Riccardo Masetti, MD, Franco Locatelli, Geertruy te Kronnie

Blood (2014) 124 (21): 4625.

https://doi.org/10.1182/blood.V124.21.4625.4625

Published: 2014

Journal Articles

Subunit a of Coagulation Factor XIII As a New Biomarker in Childhood Acute Lymphoblastic Leukemia?

Csongor Kiss, MD PhD DSc, Katalin Gyurina, László Csáthy, MD, Silvia Bresolin, PhD, Geertruy te Kronnie, PhD, Zsuzsa Hevessy, MD PhD, István Szegedi, MD PhD, Beáta Scholtz, PhD, János Kappelmayer, MD PhD DSc, Giuseppe Basso, MD

Blood (2014) 124 (21): 5346.

https://doi.org/10.1182/blood.V124.21.5346.5346

Published: 2014

Journal Articles

Refinement of IKZF1 Genomic Status in Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia

Tobia Lana, Paola de Lorenzo, Silvia Bresolin, PhD, Ilaria Bronzini, Monique L. Den Boer, MSc, PhD, Helene Cave, PhD, Eva Fronkova, MD, PhD, Martin Stanulla, MD, Marketa Zaliova, Christine J. Harrison, Hester de Groot-Kruseman, Claire Schwab, Maria Grazia Valsecchi, Andrea Biondi, Giuseppe Basso, MD, Giovanni Cazzaniga, PhD, Geertruy te Kronnie

Blood (2014) 124 (21): 3785.

https://doi.org/10.1182/blood.V124.21.3785.3785

Published: 2014

Journal Articles

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations

Roberta La Starza, Chiara Borga, Gianluca Barba, Valentina Pierini, Claire Schwab, Caterina Matteucci, Anair G. Lema Fernandez, Anna Leszl, Gianni Cazzaniga, Sabina Chiaretti, Giuseppe Basso, Christine J. Harrison, Geertruy te Kronnie, Cristina Mecucci

Blood (2014) 124 (24): 3577–3582.

https://doi.org/10.1182/blood-2014-06-578856

Published: 2014

Includes: Supplemental data

Journal Articles

PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression

Valeria Cazzaniga, Marco Giordan, Cristina Bugarin, Chiara Palmi, Angela Savino, Geertruy te Kronnie, Giuseppe Gaipa, Andrea Biondi, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD

Blood (2013) 122 (21): 3738.

https://doi.org/10.1182/blood.V122.21.3738.3738

Published: 2013

Journal Articles

Copy Number Variations and IKZF1 Mutations In Pediatric CML

Manuela Krumbholz, PhD, Josephine Tauer, Geertruy te Kronnie, Arif Ekici, Meinolf Suttorp, Markus Metzler, MD

Blood (2013) 122 (21): 1473.

https://doi.org/10.1182/blood.V122.21.1473.1473

Published: 2013

Journal Articles

Philadelphia-Like Signature In Childhood Acute Lymphoblastic Leukemia: The AIEOP Experience

Geertruy te Kronnie, Daniela Silvestri, Elena Vendramini, Grazia Fazio, PhD, Franco Locatelli, MD, Valentino Conter, Chiara Borga, Maria Grazia Valsecchi, Andrea Biondi, MD, Giuseppe Basso, Giovanni Cazzaniga, PhD

Blood (2013) 122 (21): 353.

https://doi.org/10.1182/blood.V122.21.353.353

Published: 2013

Journal Articles

New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia

Lucia Brandimarte, Valentina Pierini, Danika Di Giacomo, Chiara Borga, Filomena Nozza, Paolo Gorello, Marco Giordan, Giovanni Cazzaniga, Geertruy te Kronnie, Roberta La Starza, Cristina Mecucci

Blood (2013) 121 (25): 5064–5067.

https://doi.org/10.1182/blood-2013-02-487256

Published: 2013

Includes: Supplemental data

NARROW

Pre-Clinical Efficacy of the Novel Kinase Inhibitor Nintedanib on PAX5 Fusion Genes in Pediatric Ph-like B-Cell Precursor Acute Lymphoblastic Leukemia

Bone Marrow Mesenchymal Stromal Cells and Inflammation Contribute to ETV6-RUNX1 + Preleukemic Cells Persistence and DNA Damaging

Activin A, a Potential Key Factor of the Malignant Bone Marrow Niche, Enhances B-Cell Precursor-Acute Lymphoblastic Leukemic Cell Migratory and Invasive Properties

Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor

TET1 Promotes Leukemic Growth in T-ALL Via Maintenance of 5-Hydroxymethylation Marks and Can be Antagonized By the PARP Inhibitor Olaparib

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Targeting Mutant p53 in Pediatric Acute Lymphoblastic Leukemia

Migration of Acute Lymphoblastic Leukemia Cells into the Central Nervous System Is Regulated By VEGF

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Effective in Vivo Targeting of BCP-ALL in a NOD/SCID/huALL Mouse Model By CD70 Directed Immunotherapy

CRLF2 over-Expression Is a Poor Prognostic Marker in Children with High Risk T-Cell Acute Lymphoblastic Leukemia

The Strong Prognostic Effect of Concurrent Deletions of IKZF1 and PAX5 , CDKN2A , CDKN2B or PAR1 in the Absence of ERG Deletions (IKZF1 plus ) in Pediatric Acute Lymphoblastic Leukemia Strongly Depends on Minimal Residual Disease Burden after Induction Treatment

Secondary Mutations of JAK3 and SETBP1 in Juvenile Myelomonocytic Leukemia and Their Propagating Capacity; A Report from the AIEOP Study Group

Subunit a of Coagulation Factor XIII As a New Biomarker in Childhood Acute Lymphoblastic Leukemia?

Refinement of IKZF1 Genomic Status in Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations

PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression

Copy Number Variations and IKZF1 Mutations In Pediatric CML

Philadelphia-Like Signature In Childhood Acute Lymphoblastic Leukemia: The AIEOP Experience

New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia

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American Society of Hematology

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