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Dorothee Winterberg
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Journal Articles

The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis

Lennart Lenk, Irène Baccelli, Anna Laqua, Julia Heymann, Claas Reimer, Anna Dietterle, Dorothee Winterberg, Caroline Mary, Frédérique Corallo, Julien Taurelle, Emma Narbeburu, Stéphanie Neyton, Mylène Déramé, Sabrina Pengam, Fotini Vogiatzi, Beat Bornhauser, Jean-Pierre Bourquin, Simon Raffel, Vladyslava Dovhan, Thomas Schüler, Gabriele Escherich, Monique L. den Boer, Judith M. Boer, Wiebke Wessels, Matthias Peipp, Julia Alten, Željko Antić, Anke K. Bergmann, Martin Schrappe, Gunnar Cario, Monika Brüggemann, Nicolas Poirier, Denis M. Schewe
Journal: Blood
Blood (2024) 143 (26): 2735–2748.
https://doi.org/10.1182/blood.2023021088
Published: 2024
Includes: Supplemental data
Journal Articles

A Novel Fc-Optimized Antibody Drug Conjugate Targeting CD7 As a Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia

Carina Lynn Gehlert, Denis Martin Schewe, Katja Klausz, Steffen Krohn, Dorothee Winterberg, Fotini Vogiatzi, Ammelie Svea Boje, Anja Lux, Falk Nimmerjahn, Regina Scherließ, Andreas Humpe, Martin Schrappe, Gunnar Cario, Thomas Valerius, Lars Fransecky, Monika Brüggemann, Claudia D Baldus, Martin Gramatzki, Lennart Lenk, Christian Kellner, Matthias Peipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 4190.
https://doi.org/10.1182/blood-2023-185875
Published: 2023
Journal Articles

The IL7R-Antagonist OSE-127 Blocks Acute Lymphoblastic Leukemia Development Via a Dual Mode of Action

Lennart Lenk, Irène Baccelli, Dorothee Winterberg, Anna Dietterle, Frédérique Corallo, Julien Taurelle, Emma Narbeburu, Anna Laqua, Beat Bornhauser, Jean-Pierre Bourquin, Fotini Vogiatzi, Martin Schrappe, Gunnar Cario, Monika Brüggemann, Nicolas Poirier, Denis Martin Schewe
Journal: Blood
Blood (2022) 140 (Supplement 1): 1045–1047.
https://doi.org/10.1182/blood-2022-162261
Published: 2022
Journal Articles

Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL

Kristina Müller, Fotini Vogiatzi, Dorothee Winterberg, Thies Rösner, Lennart Lenk, Lorenz Bastian, Carina L. Gehlert, Marie-Pauline Autenrieb, Monika Brüggemann, Gunnar Cario, Martin Schrappe, Andreas E. Kulozik, Cornelia Eckert, Anke K. Bergmann, Beat Bornhauser, Jean-Pierre Bourquin, Thomas Valerius, Matthias Peipp, Christian Kellner, Denis M. Schewe
Journal: Blood
Blood (2022) 140 (1): 45–57.
https://doi.org/10.1182/blood.2021014485
Published: 2022
Includes: Supplemental data
Journal Articles

IL7R Targeting Using OSE-127 Shows Robust Anti-Leukemic Activity in B-Cell Precursor Acute Lymphoblastic Leukemia Xenografts

Lennart Lenk, Irène Baccelli, Dorothee Winterberg, Frédérique Corallo, Fotini Vogiatzi, Lea Spory, Martin Schrappe, Gunnar Cario, Anna Laqua, Monika Brüggemann, Nicolas Poirier, Denis Martin Schewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1313.
https://doi.org/10.1182/blood-2021-150323
Published: 2021
Journal Articles

Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B Cell Precursor Acute Lymphoblastic Leukemia

Lennart Lenk, Dorothee Winterberg, Fotini Vogiatzi, Anna Laqua, Lea Spory, Ahmad Mayar, Christian Vokuhl, Julia Richter, Michela Carlet, Irmela Jeremias, Thomas Valerius, Martin Schrappe, Gunnar Cario, Hassan Jumaa, Elias Hobeika, Monika Brüggemann, Ameera Alsadeq, Denis Martin Schewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 2388.
https://doi.org/10.1182/blood-2021-148429
Published: 2021
Journal Articles

Co-Targeting of CD38 and CD47 in T Cell Acute Lymphoblastic Leukemia

Fotini Vogiatzi, PhD, Kristina Müller, Dorothee Winterberg, Thies Rösner, PhD, Lennart Lenk, PhD, Gunnar Cario, MD PhD, Martin Schrappe, MDPhD, Andreas E. Kulozik, MD PhD, Beat Bornhauser, Jean-Pierre Bourquin, MD PhD, Thomas Valerius, MD, Matthias Peipp, PhD, Christian Kellner, PhD, Denis Martin Schewe, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-140270
Published: 2020
Journal Articles

Daratumumab eradicates minimal residual disease in a preclinical model of pediatric T-cell acute lymphoblastic leukemia

Fotini Vogiatzi, Dorothee Winterberg, Lennart Lenk, Swantje Buchmann, Gunnar Cario, Martin Schrappe, Matthias Peipp, Paulina Richter-Pechanska, Andreas E. Kulozik, Jana Lentes, Anke K. Bergmann, Thomas Valerius, Fabian-Simon Frielitz, Christian Kellner, Denis M. Schewe
Journal: Blood
Blood (2019) 134 (8): 713–716.
https://doi.org/10.1182/blood.2019000904
Published: 2019
Includes: Supplemental data