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Journal Articles

Venous Thromboembolism in Adolescents and Young Adults with Acute Lymphoblastic Leukemia Treated on a Pediatric-Inspired Regimen

Hari S. Raman, Shai Shimony, Yannis K. Valtis, Yael Flamand, Andrew E. Place, Lewis B. Silverman, Stephen E. Sallan, Lynda M. Vrooman, Andrew M. Brunner, Donna S. Neuberg, Ilene Galinsky, Jacqueline S. Garcia, Eric S. Winer, Martha Wadleigh, Richard M Stone, Jean M. Connors, Daniel J. DeAngelo, Marlise R. Luskin

Blood (2023) 142 (Supplement 1): 1456.

https://doi.org/10.1182/blood-2023-178353

Published: 2023

Journal Articles

Updated Results on a Multicenter Phase II Study of a Dose Intensified Pediatric Regimen in Adults with Acute Lymphoblastic Leukemia: The 06-254 DFCI ALL Consortium Trial

Yannis K. Valtis, Yael Flamand, Shai Shimony, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Martha Wadleigh, Jacqueline S. Garcia, Eric S. Winer, Ilene Galinsky, Julie Bergeron, Julie Asch, Matthew D. Seftel, Richard M Stone, Marlise R. Luskin, Daniel J. DeAngelo

Blood (2023) 142 (Supplement 1): 4238.

https://doi.org/10.1182/blood-2023-181014

Published: 2023

Journal Articles

Body Mass Index Effect on Survival and Toxicities Differs between Age Groups Among Adolescents and Young Adults Treated on DFCI Consortium ALL Trials

Shai Shimony, Yael Flamand, Yannis K. Valtis, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Richard M. Stone, Martha Wadleigh, Donna S. Neuberg, Daniel J DeAngelo, Marlise R. Luskin

Blood (2022) 140 (Supplement 1): 3164–3165.

https://doi.org/10.1182/blood-2022-158348

Published: 2022

Journal Articles

Adolescent and Young Adults with ALL Who Complete Therapy on DFCI Consortium ALL Trials Have Excellent Long-Term Overall Survival

Yannis K. Valtis, Yael Flamand, Shai Shimony, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Martha Wadleigh, Richard M. Stone, Daniel J DeAngelo, Marlise R. Luskin

Blood (2022) 140 (Supplement 1): 8901–8903.

https://doi.org/10.1182/blood-2022-159286

Published: 2022

Journal Articles

Nelarabine Combination Therapy for Relapsed or Refractory T-Cell Acute Lymphoblastic Lymphoma/Leukemia

Shai Shimony, Yiwen Liu, Yannis K. Valtis, Jonathan D. Paolino, Andrew E. Place, Andrew M. Brunner, Lachelle D. Weeks, Lewis B. Silverman, Lynda M. Vrooman, Donna S. Neuberg, Richard M. Stone, Daniel J. DeAngelo, Marlise R. Luskin

Blood (2022) 140 (Supplement 1): 8989–8990.

https://doi.org/10.1182/blood-2022-157545

Published: 2022

Journal Articles

A Meta-Analysis of Hypersensitivity to Pegylated Escherichia coli Asparaginase Used As First-Line Treatment in Contemporary Pediatric Acute Lymphoblastic Leukemia Protocols

Leiah Brigitha, Marta Fiocco, Rob Pieters, Birgitte Klug Albertsen, Gabriele Escherich, Elixabet Lopez-Lopez, Veerle Mondelaers, Ajay Vora, Lynda M. Vrooman, Kjeld Schmiegelow, Inge M. Van Der Sluis

Blood (2021) 138 (Supplement 1): 2308.

https://doi.org/10.1182/blood-2021-144674

Published: 2021

Journal Articles

Impact of Age, Body Surface Area, and Body Mass Index on Pegaspargase Toxicity and Pharmacokinetics: A Report from the DFCI ALL Consortium

Blood (2021) 138 (Supplement 1): 3396.

https://doi.org/10.1182/blood-2021-151313

Published: 2021

Journal Articles

Pegaspargase Re-Challenge after Grade 2 Hypersensitivity Reaction in Childhood Acute Lymphoblastic Leukemia: Results from DFCI 16-001

Lynda M. Vrooman, MD, Yael Flamand, MS, Victoria Koch, BS, Melissa A. Burns, MD, Sarah M. Cronholm, BA, Sarah K. Hunt, BS, MPH, Peter D. Cole, MD, Lisa M. Gennarini, MD, Justine M. Kahn, MDMSc, Kara M. Kelly, MD, Bruno Michon, MD FRCPC, Donna S. Neuberg, ScD, Andrew E. Place, MDPhD, Thai Hoa Tran, MD, Jennifer J.G. Welch, MD, Kristen E. Stevenson, MS, Stephen E. Sallan, MD, Lewis B. Silverman, MD

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-138840

Published: 2020

Journal Articles

Orthopedic Toxicity Among Adolescents and Young Adults Treated on DFCI ALL Consortium Trials

Yannis K. Valtis, MD, Kristen E. Stevenson, MS, Andrew E. Place, MDPhD, Lewis B. Silverman, MD, Lynda M. Vrooman, MD, Giacomo Gotti, MD, Andrew M. Brunner, MD, Mary Nauffel, Daniel J. DeAngelo, MD PhD, Marlise R Luskin, MDMS

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-137488

Published: 2020

Journal Articles

Randomized Study of Pegasparagase (SS-PEG) and Calaspargase Pegol (SC-PEG) in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma: Results of DFCI ALL Consortium Protocol 11-001

Blood (2016) 128 (22): 175.

https://doi.org/10.1182/blood.V128.22.175.175

Published: 2016

Journal Articles

Asparaginase-Associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Report on Clinical Presentation and Outcome

Blood (2016) 128 (22): 585.

https://doi.org/10.1182/blood.V128.22.585.585

Published: 2016

Journal Articles

Effect of Dexrazoxane on Heart Function Among Long-Term Survivors of Childhood Leukemia and Lymphoma: A Report from the Children's Oncology Group (COG)

Eric J Chow, MD MPH, David R. Doody, MS, Saro H. Armenian, DO, MPH, Sanjeev Aggarwal, MD, K. Scott Baker, MD MS, Smita Bhatia, MD MPH, Nancy A. Blythe, BA, Louis S. Constine, MD, David R. Freyer, DO, MS, Lisa M. Kopp, DO, Wendy M. Leisenring, ScD, Nao Sasaki, MD, Lynda M. Vrooman, MD MSc, Barbara L. Asselin, MD, Cindy L. Schwartz, MD MPH, Steven E. Lipshultz, MD FAAP, FAHA

Blood (2016) 128 (22): 696.

https://doi.org/10.1182/blood.V128.22.696.696

Published: 2016

Journal Articles

Homozygosity for the 2R Tandem Repeat Polymorphism in the Thymidylate Synthase (TS) Promoter Is Associated with Increased Risk for Bony Morbidity Among Children Treated for Acute Lymphoblastic Leukemia on DFCI Protocol 05-001

Peter D. Cole, MD, Traci M. Blonquist, MS, Veena Vijayanathan, PhD, Donna S. Neuberg, Sc.D., Lynda M. Vrooman, MD, Stephen E. Sallan, MD, Lewis B. Silverman, MD, Yaron Finkelstein, MD

Blood (2015) 126 (23): 251.

https://doi.org/10.1182/blood.V126.23.251.251

Published: 2015

Journal Articles

Preliminary Results Of a Pharmacokinetic Study Of Intravenous Asparaginase Erwinia Chrysanthemi Following Allergy To E Coli -Derived Asparaginase In Children, Adolescents, and Young Adults With Acute Lymphoblastic Leukemia Or Lymphoblastic Lymphoma

Lynda M. Vrooman, MD, Ivan I. Kirov, MD, Zoann E. Dreyer, MD, Michael Kelly, MD, PhD, Nobuko Hijiya, MD, Patrick Brown, MD, Richard A. Drachtman, MD, Yoav H Messinger, MD, A. Kim Ritchey, MD, Gregory A. Hale, MD, Kelly Maloney, MD, Paul V. Plourde, MD, Lewis B. Silverman, MD

Blood (2013) 122 (21): 3904.

https://doi.org/10.1182/blood.V122.21.3904.3904

Published: 2013

Journal Articles

Results Of The DFCI ALL Consortium Protocol 05-001 For Children and Adolescents With Newly Diagnosed ALL

Lewis B. Silverman, MD, Kristen E. Stevenson, MS, Uma H. Athale, M.D., M.Sc., Luis A. Clavell, MD, Peter Cole, MD, Kara A. Kelly, MD, Jean-Marie Leclerc, MD, Bruno Michon, MD, FRCPC, Marshall A. Schorin, MD, Cindy L Schwartz, MD, MPH, Barbara Asselin, MD, Jeffrey G Supko, PhD, Sarah Hunt, MPH, Place Andrew, MD, PhD, Lynda M. Vrooman, MD, Donna S. Neuberg, ScD, Stephen E. Sallan, MD

Blood (2013) 122 (21): 838.

https://doi.org/10.1182/blood.V122.21.838.838

Published: 2013

Journal Articles

Intensified Chemotherapy Regimen for Very High Risk Childhood B-Precursor Acute Lymphoblastic Leukemia (B-ALL): Results From Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocol 05–01

Lynda M. Vrooman, MD, Kristen E. Stevenson, MS, Marian Harris, MD, Donna S. Neuberg, ScD, Stephen E. Sallan, MD, Lewis B. Silverman, MD

Blood (2012) 120 (21): 3563.

https://doi.org/10.1182/blood.V120.21.3563.3563

Published: 2012

Journal Articles

Randomized Comparison of IV PEG and IM E. Coli Asparaginase in Children and Adolescents with Acute Lymphoblastic Leukemia: Results of the DFCI ALL Consortium Protocol 05-01

Lewis B. Silverman, MD, Kristen Stevenson, Lynda M Vrooman, MD, Jeffrey G Supko, PhD, Barbara Asselin, MD, Uma Athale, MD, Luis A. Clavell, MD, Peter Cole, MD, Kara M Kelly, MD, Caroline Laverdiere, MD, Bruno Michon, MD, FRCPC, Marshall A. Schorin, MD, Cindy Schwartz, MD, MPH, Donna Neuberg, ScD, Stephen E. Sallan, MD

Blood (2011) 118 (21): 874.

https://doi.org/10.1182/blood.V118.21.874.874

Published: 2011

Journal Articles

Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia

Lewis B. Silverman, Jeffrey G. Supko, Kristen E. Stevenson, Christina Woodward, Lynda M. Vrooman, Donna S. Neuberg, Barbara L. Asselin, Uma H. Athale, Luis Clavell, Peter D. Cole, Kara M. Kelly, Caroline Laverdière, Bruno Michon, Marshall Schorin, Cindy L. Schwartz, Jane E. O'Brien, Harvey J. Cohen, Stephen E. Sallan

Blood (2010) 115 (7): 1351–1353.

https://doi.org/10.1182/blood-2009-09-245951

Published: 2010

Journal Articles

Dexamethasone and Individualized Asparaginase Dosing Are Each Associated with Superior Event-Free Survival in Childhood Acute Lymphoblastic Leukemia: Results From DFCI-ALL Consortium Protocol 00-01.

Lynda M. Vrooman, MD, Donna S. Neuberg, ScD, Kristen E. Stevenson, MS, Jeffrey G. Supko, PhD, Stephen E. Sallan, MD, Lewis B. Silverman, MD

Blood (2009) 114 (22): 321.

https://doi.org/10.1182/blood.V114.22.321.321

Published: 2009

Journal Articles

Increased Risk of Skeletal Toxicity and Infection in Children 10 Years or Older Treated for Acute Lymphoblastic Leukemia (ALL) with Dexamethasone: Results from the DFCI ALL Consortium.

Lynda M. Vrooman, Donna Neuberg, Jane O’Brien, Stephen E. Sallan, Lewis B. Silverman

Blood (2007) 110 (11): 849.

https://doi.org/10.1182/blood.V110.11.849.849

Published: 2007

NARROW

Venous Thromboembolism in Adolescents and Young Adults with Acute Lymphoblastic Leukemia Treated on a Pediatric-Inspired Regimen

Updated Results on a Multicenter Phase II Study of a Dose Intensified Pediatric Regimen in Adults with Acute Lymphoblastic Leukemia: The 06-254 DFCI ALL Consortium Trial

Body Mass Index Effect on Survival and Toxicities Differs between Age Groups Among Adolescents and Young Adults Treated on DFCI Consortium ALL Trials

Adolescent and Young Adults with ALL Who Complete Therapy on DFCI Consortium ALL Trials Have Excellent Long-Term Overall Survival

Nelarabine Combination Therapy for Relapsed or Refractory T-Cell Acute Lymphoblastic Lymphoma/Leukemia

A Meta-Analysis of Hypersensitivity to Pegylated Escherichia coli Asparaginase Used As First-Line Treatment in Contemporary Pediatric Acute Lymphoblastic Leukemia Protocols

Impact of Age, Body Surface Area, and Body Mass Index on Pegaspargase Toxicity and Pharmacokinetics: A Report from the DFCI ALL Consortium

Pegaspargase Re-Challenge after Grade 2 Hypersensitivity Reaction in Childhood Acute Lymphoblastic Leukemia: Results from DFCI 16-001

Orthopedic Toxicity Among Adolescents and Young Adults Treated on DFCI ALL Consortium Trials

Randomized Study of Pegasparagase (SS-PEG) and Calaspargase Pegol (SC-PEG) in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma: Results of DFCI ALL Consortium Protocol 11-001

Asparaginase-Associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Report on Clinical Presentation and Outcome

Effect of Dexrazoxane on Heart Function Among Long-Term Survivors of Childhood Leukemia and Lymphoma: A Report from the Children's Oncology Group (COG)

Homozygosity for the 2R Tandem Repeat Polymorphism in the Thymidylate Synthase (TS) Promoter Is Associated with Increased Risk for Bony Morbidity Among Children Treated for Acute Lymphoblastic Leukemia on DFCI Protocol 05-001

Preliminary Results Of a Pharmacokinetic Study Of Intravenous Asparaginase Erwinia Chrysanthemi Following Allergy To E Coli -Derived Asparaginase In Children, Adolescents, and Young Adults With Acute Lymphoblastic Leukemia Or Lymphoblastic Lymphoma

Results Of The DFCI ALL Consortium Protocol 05-001 For Children and Adolescents With Newly Diagnosed ALL

Intensified Chemotherapy Regimen for Very High Risk Childhood B-Precursor Acute Lymphoblastic Leukemia (B-ALL): Results From Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocol 05–01

Randomized Comparison of IV PEG and IM E. Coli Asparaginase in Children and Adolescents with Acute Lymphoblastic Leukemia: Results of the DFCI ALL Consortium Protocol 05-01

Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia

Dexamethasone and Individualized Asparaginase Dosing Are Each Associated with Superior Event-Free Survival in Childhood Acute Lymphoblastic Leukemia: Results From DFCI-ALL Consortium Protocol 00-01.

Increased Risk of Skeletal Toxicity and Infection in Children 10 Years or Older Treated for Acute Lymphoblastic Leukemia (ALL) with Dexamethasone: Results from the DFCI ALL Consortium.

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American Society of Hematology

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