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Guanlin Wang
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Journal Articles

Cooperation between SF3B1 and JAK2 V617F Mutations Accelerates Fibrotic Progression in Myeloproliferative Neoplasms By Enhancing STAT1 Signaling

Jennifer O Sullivan, Sean Wen, Affaf Aliouat, Alba Rodriguez-Meira, Sally-Ann Clark, Neil Ashley, Amy Wood, Ramy Slama, Guanlin Wang, Angela Hamblin, Lauren Murphy, Christina Simoglou Karali, Charlotte K Brierley, Adam P Cribbs, Aimee Paterson, Claire N Harrison, Bethan Psaila, Adam J Mead
Journal: Blood
Blood (2023) 142 (Supplement 1): 861.
https://doi.org/10.1182/blood-2023-185118
Published: 2023
Journal Articles

Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms

Rong Li, Michela Colombo, Guanlin Wang, Sally-Ann Clark, Antonio Rodriguez-Romera, Yiran Meng, Abdullah Khan, Wei Xiong Wen, Nikolaos Sousos, Lauren Murphy, Christina Simoglou Karali, Korsuk Sirinukunwattana, Jennifer O'Sullivan, Ruggiero Norfo, Qian Cheng, Charlotte Brierley, Joana Carrelha, Zemin Ren, Gabriel A. Rabinovich, Vijay A Rathinam, Supat Thongjuea, Daniel Royston, Adam J Mead, Bethan Psaila
Journal: Blood
Blood (2022) 140 (Supplement 1): 1091–1092.
https://doi.org/10.1182/blood-2022-165493
Published: 2022
Journal Articles

Human Bone Marrow Organoids Enable the Study of Hematopoietic Cell-Stromal Interactions and Support the Survival of Malignant Cells from Patients

Abdullah Khan, Antonio Rodriguez-Romera, Michela Colombo, Jasmeet S Reyat, Guanlin Wang, Wei Xiong Wen, Lauren C Murphy, Rebecca Ling, Natalina Elliott, Nikolaos Sousos, Samuel Kemble, Beata Grygielska, Christopher Mahoney, Andrew P. Stone, Adam P Croft, David Bassett, Gowsihan Poologasundarampillai, Adele K. Fielding, Emily A. Cutler, Anindita Roy, Sarah Gooding, Julie Rayes, Kellie Machlus, Bethan Psaila
Journal: Blood
Blood (2022) 140 (Supplement 1): 1679–1681.
https://doi.org/10.1182/blood-2022-164881
Published: 2022
Journal Articles

CD34 + CD19 − CD22 + B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

Brief Report
Clara Bueno, Susana Barrera, Alex Bataller, Valentín Ortiz-Maldonado, Natalina Elliot, Sorcha O’Byrne, Guanlin Wang, Montse Rovira, Francisco Gutierrez-Agüera, Juan L. Trincado, María González-González, Mireia Morgades, Marc Sorigué, Paloma Bárcena, Samanta Romina Zanetti, Montse Torrebadell, Nerea Vega-Garcia, Susana Rives, Mar Mallo, Francesc Sole, Adam J. Mead, Irene Roberts, Supat Thongjuea, Bethan Psaila, Manel Juan, Julio Delgado, Alvaro Urbano-Ispizúa, Josep María Ribera, Alberto Orfao, Anindita Roy, Pablo Menendez
Journal: Blood
Blood (2022) 140 (1): 38–44.
https://doi.org/10.1182/blood.2021014840
Published: 2022
Includes: Supplemental data
Journal Articles

Single-Cell Multi-Omics Reveals the Genetic, Cellular and Molecular Landscape of TP53 Mutated Leukemic Transformation in MPN

Alba Rodriguez-Meira, Haseeb Rahman, Ruggiero Norfo, Wei Wen, Agathe Chédeville, Jennifer O'Sullivan, Guanlin Wang, Aimee Paterson, Eleni Louka, Charlotte K Brierley, Warren W Kretzschmar, Francois Girodon, Zemin Ren, Matthew Bashton, Amir Enshaei, Mark W. Drummond, Florence Pasquier, Christophe Marzac, Claire N. Harrison, Isabelle Plo, Sten Eirik W Jacobsen, Supat Thongjuea, Bethan Psaila, Ileana Antony-Debre, Adam J. Mead
Journal: Blood
Blood (2021) 138 (Supplement 1): 3.
https://doi.org/10.1182/blood-2021-150191
Published: 2021
Journal Articles

Single-Cell Transcriptional Landscapes of Human Bone Marrow Reveal Distinct Erythroid Phenotypes Underpinned By Genotype in Diamond-Blackfan Anemia

Deena Iskander, MD, Guanlin Wang, PhD, Elisabeth F Heuston, PhD, Chrysi Christodoulidou, Bethan Psaila, MD PhD, Mark E Robinson, PhD, Aristeidis Chaidos, MD PhD, Pritesh Trivedi, MSc, Nikolaos Trasanidis, PhD, Alexia Katsarou, MD, Richard Szydlo, PhD, NISC Comparative SequencingProgram, Qais Al-Oqaily, MD PhD, Valentina S Caputo, PhD, Kanagaraju Ponnusamy, PhD, Anindita Roy, MD PhD, Leena Karnik, FRCPath, MRCP, Kikkeri Naresh, MD, Adam J. Mead, MD PhD, Supat Thongjuea, PhD, Marjorie Brand, PhD, Josu de la Fuente, David M. Bodine, PhD, Irene Roberts, MD PhD, Anastasios Karadimitris, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-141535
Published: 2020
Journal Articles

Single-cell analysis of bone marrow–derived CD34 + cells from children with sickle cell disease and thalassemia

Peng Hua, Noemi Roy, Josu de la Fuente, Guanlin Wang, Supat Thongjuea, Kevin Clark, Anindita Roy, Bethan Psaila, Neil Ashley, Yvonne Harrington, Claus Nerlov, Suzanne M. Watt, Irene Roberts, James O. J. Davies
Journal: Blood
Blood (2019) 134 (23): 2111–2115.
https://doi.org/10.1182/blood.2019002301
Published: 2019
Includes: Supplemental data