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Journal Articles

Integrative Analysis of the Genomic and Transcriptomic Landscape of Relapsed/Refractory Multiple Myeloma Patients Treated With Venetoclax in Combination With Bortezomib and Dexamethasone: Biomarker Analyses From the Phase 3 BELLINI Study

Michael E. O'Dwyer, MD, Andrew Spencer, MBBS, FRACP, FRCPA, DM, Shaji K. Kumar, MD, Rakesh Popat, Philippe Moreau, MD, Monique Dail, PhD, Muhammad Jalaluddin, PhD, Xiaoqing Yang, PhD, Xin Lu, Zheng Zha, Fengjiao Dunbar, PhD, Deeksha Vishwamitra, PhD, Christine Mantis, PhD, Amal Melhem-Bertrandt, MD, Jeremy A. Ross, Simon J Harrison, MBBS MRCP (UK) PhDFRCPath (UK) FRACP
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-134710
Published: 2020
Journal Articles

Ex Vivo Drug Sensitivity and Functional Genomics Platform Identifies Novel Combinations Targeting Intrinsic and Extrinsic Apoptotic Signaling Pathways in Multiple Myeloma

Ariosto Siqueira Silva, PhD, Rafael Renatino-Canevarolo, PhD, Mark B. Meads, PhD, Maria D Coelho Siqueira Silva, MSc, Praneeth Reddy Sudalagunta, PhD, Christopher Cubitt, Gabriel De Avila, BS, Raghunandan Reddy Alugubelli, Amit Kulkarni, PhD, Melissa Mitchell, Hongyue Dai, Qi Zhang, PhD, Oliver Hampton, Xin Lu, Dimple A. Modi, PhD, Monica Motwani, PhD, Jason Harb, PhD, Jeremy A. Ross, Kenneth H. Shain, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 49–50.
https://doi.org/10.1182/blood-2020-134924
Published: 2020
Journal Articles

Selective Targeting BET Family Bdii Bromodomain with Abbv-744 and BCL-2 with Venetoclax (ABT-199) Is Synergistic in Primary Acute Myeloid Leukemia Models

Tianyu Cai, PhD, Vinitha Mary Kuruvilla, MSc, Xiaoyu Lin, Tamar Uziel, PhD, Xin Lu, Lu Zhang, Xiaoli Huang, Qi Zhang, PhD, Antonio Cavazos, Lina Han, PhD, Yu Shen, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1369.
https://doi.org/10.1182/blood-2019-128618
Published: 2019
Journal Articles

Targeting the Second Bromodomain (BDII) of BET Family with Abbv-744 Results in Robust Anti-Leukemia Activity in AML Models with Excellent In Vivo Tolerability

Tianyu Cai, PhD, Vinitha Mary Kuruvilla, Tamar Uziel, PhD, Qi Zhang, PhD, Lina Han, PhD, Antonio Cavazos, MSc, Yu Shen, Marina Y. Konopleva, MD PhD, Xiaoyu Lin, Xin Lu, Lu Zhang
Journal: Blood
Blood (2018) 132 (Supplement 1): 1439.
https://doi.org/10.1182/blood-2018-99-116912
Published: 2018
Journal Articles

Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres

Brief Report
Jianwei Wang, Xin Lu, Vadim Sakk, Christoph A. Klein, Karl Lenhard Rudolph
Journal: Blood
Blood (2014) 124 (22): 3237–3240.
https://doi.org/10.1182/blood-2014-04-568055
Published: 2014
Includes: Supplemental data
Journal Articles

Whole-Genome Sequencing of a Monozygotic Twin Pair Reveals Functional Cooperative Mutations of SETD2 in Acute Leukemia

Xiaofan Zhu, Fuhong He, Huimin Zeng, Shaoping Ling, Xiaomei Yan, Yaqin Wang, Aili Chen, Wei Wei, Yue Zhang, Hui Cheng, Jun Wu, Xia Li, Lingtong Hao, Lihua Cao, Lili Dong, Wei Zou, Xuejing Yang, Xin Lu, Si Zheng, Jin Yan, Jing Zhou, Lixia Zhang, Shuangli Mi, Xiaojuan Wang, Li Zhang, Yao Zou, Yumei Chen, Zhe Geng, Jianfeng Zhou, Jianmin Wang, Xin Liu, Jianxiang Wang, Gang Huang, Weiping Yuan, Tao Cheng, Qian-fei Wang
Journal: Blood
Blood (2012) 120 (21): 781.
https://doi.org/10.1182/blood.V120.21.781.781
Published: 2012
Journal Articles

Shear Stress Directly Regulates Platelet αIIbβ3 Signaling.

Shuju Feng, PhD, Xin Lu, BS, Julio C. Resendiz, Michael H. Kroll, MD
Journal: Blood
Blood (2005) 106 (11): 3570.
https://doi.org/10.1182/blood.V106.11.3570.3570
Published: 2005
Journal Articles

Filamin Binding to Glycoprotein Ibα Signals Talin-Directed α IIbβ 3 Activation.

Shuju Feng, PhD, Xin Lu, BS, Michael H. Kroll, MD
Journal: Blood
Blood (2005) 106 (11): 383.
https://doi.org/10.1182/blood.V106.11.383.383
Published: 2005
Journal Articles

A Novel Method of Isolation of Mesenchymal Stem Cells from Human Umbilical Cord Tisssues.

Lulu Lu, MD, Yong-jun Liu, MD, Zhen-shu Xu, MD, Cun-gang Fan, MD, Han Wang, MD, Wei Gong, MD, Zhi-bo Han, MD, Yong-xin Lu, MD, Delong Liu, MD, PhD, Zhi-zhe Chen, MD, Zhong-chao Han, MD
Journal: Blood
Blood (2005) 106 (11): 4306.
https://doi.org/10.1182/blood.V106.11.4306.4306
Published: 2005
Journal Articles

Posttranslational modifications of p27 kip1 determine its binding specificity to different cyclins and cyclin-dependent kinases in vivo

Wenqing Zhang, Daniele Bergamaschi, Boquan Jin, Xin Lu
Journal: Blood
Blood (2005) 105 (9): 3691–3698.
https://doi.org/10.1182/blood-2003-07-2558
Published: 2005
Journal Articles

Filamin A Binding Stabilizes Nascent Glycoprotein Ibα Trafficking and Thereby Enhances Its Surface Expression.

Shuju Feng, PhD, Xin Lu, BS, Michael H. Kroll, MD
Journal: Blood
Blood (2004) 104 (11): 3656.
https://doi.org/10.1182/blood.V104.11.3656.3656
Published: 2004
Journal Articles

A Contractile Cytoskeletal Tether Modulates Signaling between Glycoprotein Ibα and αIIbβ3.

Shuju Feng, PhD, Xin Lu, BS, Michael H. Kroll, MD
Journal: Blood
Blood (2004) 104 (11): 1554.
https://doi.org/10.1182/blood.V104.11.1554.1554
Published: 2004
Journal Articles

Filamin A binding to the cytoplasmic tail of glycoprotein Ibα regulates von Willebrand factor–induced platelet activation

Shuju Feng, Julio C. Reséndiz, Xin Lu, Michael H. Kroll
Journal: Blood
Blood (2003) 102 (6): 2122–2129.
https://doi.org/10.1182/blood-2002-12-3805
Published: 2003