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Journal Articles

Functional Diversification and Dynamics of CAR-T Cells in B-ALL Patients

Zongcheng Li, Lei Zhao, Yuanyuan Zhang, Li Zhu, Wei Mu, Tong Ge, Jin Jin, Jiaqi Tan, Jiali Cheng, Jue Wang, Na Wang, Xiaoxi Zhou, Liting Chen, Zhilin Chang, Chen Liu, Bian Zhilei, Bing Liu, Lilin Ye, Yu Lan, Liang Huang, Jianfeng Zhou
Journal: Blood
Blood (2023) 142 (Supplement 1): 4851.
https://doi.org/10.1182/blood-2023-178624
Published: 2023
Journal Articles

Radiation Prior to Chimeric Antigen Receptor T-Cell Therapy Is an Optimizing Bridging Strategy in Relapse/Refractory Aggressive B-Cell Lymphoma

Qiuxia Yu, Xiaoying Zhang, Na Wang, Liang Huang, Chunrui Li, Yicheng Zhang, Jianfeng Zhou, Gaoxiang Wang, Yang Cao
Journal: Blood
Blood (2022) 140 (Supplement 1): 10311–10312.
https://doi.org/10.1182/blood-2022-165174
Published: 2022
Journal Articles

Chidamide Plus Prednisone, Cyclophosphamide, and Thalidomide (CPCT) for Relapsed or Refractory Peripheral T-Cell Lymphoma: A Multicenter Phase II Trial

Wei Xu, Jin-Hua Liang, Li Wang, Xiao-Dong Wang, Guohui Cui, Jianfeng Zhou, Jingyan Xu, Luqun Wang, Rong Liang, Bi-yun Chen, Jian Cheng, Jian-Yong Li
Journal: Blood
Blood (2022) 140 (Supplement 1): 9484–9486.
https://doi.org/10.1182/blood-2022-157014
Published: 2022
Journal Articles

The Safety and Efficacy of p CAR-19B, a Scfv Humanlized CD19-Directed CAR-T for Patients with Relapsed/Refactory (R/R) CD19+ B-ALL

Zhenya Hong, Zhi Yang, Xiaoxi Zhou, Gaoxiang Wang, Mi Zhou, Yingzi Zhang, Peiling Zhang, Jinjin Huang, Li Meng, Haitao Ruan, Min Xiao, Yunyan Li, Linling Wang, Meiling Wang, Wei Zhu, Qianzhen Zhang, Junjie Shen, Jianfeng Zhou, Cheng Qian, Liang Huang
Journal: Blood
Blood (2022) 140 (Supplement 1): 4625–4626.
https://doi.org/10.1182/blood-2022-162134
Published: 2022
Journal Articles

Efficacy and safety of CD19-specific CAR T cell–based therapy in B-cell acute lymphoblastic leukemia patients with CNSL

Clinical Trials & Observations
Yuekun Qi, Mingfeng Zhao, Yongxian Hu, Ying Wang, Ping Li, Jiang Cao, Ming Shi, Jiaqi Tan, Meng Zhang, Xia Xiao, Jieyun Xia, Sha Ma, Jianlin Qiao, Zhiling Yan, Hujun Li, Bin Pan, Wei Sang, Depeng Li, Zhenyu Li, Jianfeng Zhou, He Huang, Aibin Liang, Junnian Zheng, Kailin Xu
Journal: Blood
Blood (2022) 139 (23): 3376–3386.
https://doi.org/10.1182/blood.2021013733
Published: 2022
Includes: Supplemental data
Journal Articles

Zanubrutinib in relapsed/refractory mantle cell lymphoma: long-term efficacy and safety results from a phase 2 study

Clinical Trials & Observations
Yuqin Song, Keshu Zhou, Dehui Zou, Jianfeng Zhou, Jianda Hu, Haiyan Yang, Huilai Zhang, Jie Ji, Wei Xu, Jie Jin, Fangfang Lv, Ru Feng, Sujun Gao, Haiyi Guo, Lei Zhou, Jane Huang, William Novotny, Pil Kim, Yiling Yu, Binghao Wu, Jun Zhu
Journal: Blood
Blood (2022) 139 (21): 3148–3158.
https://doi.org/10.1182/blood.2021014162
Published: 2022
Includes: Supplemental data
Journal Articles

Outcomes of Relapsed/Refractory Aggressive B-Cell Non-Hodgkin Lymphoma (r/r B-NHL) Patients with TP53 Gene Disruption Treated with CD19/22 Cocktail CAR T-Cell Therapy Alone or Incorporated with Autologous Stem Cell Transplantation (ASCT)

JIA Wei, Min Xiao, Zekai Mao, Yang Cao, Yi Xiao, Fankai Meng, Yicheng Zhang, Jianfeng Zhou, Liang Huang
Journal: Blood
Blood (2021) 138 (Supplement 1): 94.
https://doi.org/10.1182/blood-2021-147278
Published: 2021
Journal Articles

A Phase 1/2 Study of a Novel Fully Human B-Cell Maturation Antigen-Specific CAR T Cells (CT103A) in Patients with Relapsed and/or Refractory Multiple Myeloma

Chunrui Li, Di Wang, Yongping Song, Jianyong Li, He Huang, Bing Chen, Jing Liu, Kai Hu, Hanyun Ren, Xi Zhang, Zhenyu Li, Dehui Zou, Qingsong Yin, Lijuan Chen, Yongxian HU, Yong Xu, Qian Cheng, Yuelu Guo, Yujun Dong, Li Gao, Aining Xu, Songbai Cai, Wen Wang, Ming Wu, Jue Wang, Liting Chen, Jianfeng Zhou, Lugui Qiu
Journal: Blood
Blood (2021) 138 (Supplement 1): 547.
https://doi.org/10.1182/blood-2021-152576
Published: 2021
Journal Articles

Orelabrutinib Monotherapy in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Updated Long Term Results of Phase II Study

Wei Xu, Yongping Song, Tingyu Wang, Shenmiao Yang, Lihong Liu, Yu Hu, Wei Zhang, Jianfeng Zhou, Sujun Gao, Kaiyang Ding, Huilai Zhang, Zunmin Zhu, Shunqing Wang, Bing Xu, Jianda Hu, Ting Liu, Chunyan Ji, Zhongjun Xia, Yan Li, Xin Wang, Bin Zhang, Renbin Zhao, Jianyong Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 2638.
https://doi.org/10.1182/blood-2021-146491
Published: 2021
Journal Articles

A phase 1 study of a novel fully human BCMA-targeting CAR (CT103A) in patients with relapsed/refractory multiple myeloma

Clinical Trials & Observations
Di Wang, Jue Wang, Guang Hu, Wen Wang, Yi Xiao, Haodong Cai, Lijun Jiang, Li Meng, Yongkun Yang, Xiaoxi Zhou, Zhenya Hong, Zheng Yao, Min Xiao, Liting Chen, Xia Mao, Li Zhu, Jin Wang, Lugui Qiu, Chunrui Li, Jianfeng Zhou
Journal: Blood
Blood (2021) 137 (21): 2890–2901.
https://doi.org/10.1182/blood.2020008936
Published: 2021
Includes: Supplemental data
Journal Articles

Results from a Phase 1 Dose Escalation Study of HMPL-689, a Selective Oral Phosphoinositide 3-Kinase-Delta Inhibitor, in Chinese Patients with Relapsed/Refractory (R/R) Lymphomas

Junning Cao, Zhiming Li, MD PhD, Jianfeng Zhou, MD PhD, Dongmei Ji, MD PhD, Weina Shen, PhD, Peng Sun, MD, Yu Wang, MD, Dengju Li, MD, Zhenya Hong, MDPhD, Gaoxiang Wang, MDPhD, Xianlin Duan, MD, Chen Yu, MD, Yu Cai, PhD, Weiguo Su, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38.
https://doi.org/10.1182/blood-2020-136013
Published: 2020
Journal Articles

Tumor Microenvironment Associated with Complete Response to Tislelizumab Monotherapy in Relapsed/Refractory Classical Hodgkin Lymphoma Reveals a Potentially Different Mechanism of Action

Yuqin Song, MD PhD, Quanli Gao, MD, Lei Fan, MD PhD, Dehui Zou, MD, Huilai Zhang, MD PhD, Jianfeng Zhou, MD PhD, Wei Li, MD, Haiyan Yang, MD PhD, Ting Liu, MD PhD, Quanshun Wang, MD PhD, Fangfang Lv, MD, Dan Wang, PhD, Pei Zhang, PhD, Tengfei Liu, PhD, Yun Zhang, PhD, Zhirong Shen, PhD, Lei Wang, PhD, Liudi Yang, MD, Haiyi Guo, MD, Jun Zhu, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-136696
Published: 2020
Journal Articles

Anti CD19/22 Cocktail CAR T-Cell Therapy Can Improve the Outcomes of Patients with TP53-Mutated Relapsed/Refractory B-Cell Lymphoma

JIA Wei, MDPhD, Min Xiao, Zekai Mao, Na Wang, MD PhD, Chunrui Li, MDPhD, Yang Cao, Weimin Sun, Yi Xiao, Chaojiang Gu, Shangkun Zhang, PhD, Yicheng Zhang, Tongcun Zhang, PhD, Jianfeng Zhou, MD PhD, Liang Huang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43.
https://doi.org/10.1182/blood-2020-138947
Published: 2020
Journal Articles

Earlier Use of Zanubrutinib Monotherapy in Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Is Associated with Greater Efficacy: A Pooled Analysis from 3 Studies

Wei Xu, Shenmiao Yang, Constantine S. Tam, MBBS, MD, John F. Seymour, Keshu Zhou, MD PhD, Stephen Opat, MBBS (Hons), FRACP, FRCPA, Lugui Qiu, MD, Mingyuan Sun, Tingyu Wang, Judith Trotman, FRACP, Ling Pan, MD PhD, Sujun Gao, Jianfeng Zhou, MD PhD, Daobin Zhou, MD PhD, Jun Zhu, Yuqin Song, MD PhD, Jianda Hu, MDPhD, Ru Feng, Haiwen Huang, Zhiyue Huang, Huafei Lu, Jianyong Li, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-136236
Published: 2020
Journal Articles

Safety and Efficacy of the Bruton Tyrosine Kinase Inhibitor Zanubrutinib (BGB-3111) in Patients with WaldenstrC6m Macroglobulinemia from a Phase 2 Trial

Gang An, MD PhD, Daobin Zhou, MD PhD, Weili Zhao, MD PhD, Keshu Zhou, MD PhD, Jianyong Li, MD PhD, Jianfeng Zhou, MD PhD, Liping Xie, MD PhD, Jie Jin, MD PhD, Liye Zhong, MD PhD, Lingzhi Yan, MD PhD, Haiyi Guo, MD, Chenmu Du, MD, Jane Huang, MD, William Novotny, MD, Jinhua Zhong, PhD, Lugui Qiu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-136783
Published: 2020
Journal Articles

CD19/CD22 CAR-T Cell Cocktail Therapy Following Autologous Transplantation in Patients with Relapsed/Refractory B-Cell Lymphomas

Yang Cao, Yi Xiao, Na Wang, MD PhD, Gaoxiang Wang, MDPhD, Xiaoxi Zhou, MDPhD, Liang Huang, MD, Liting Chen, PhD, Min Xiao, MD PhD, Tongcun Zhang, PhD, Yicheng Zhang, Jianfeng Zhou, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11.
https://doi.org/10.1182/blood-2020-140308
Published: 2020
Journal Articles

Updated Results from the Phase II Study of Orelabrutinib Monotherapy in Chinese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Cell Leukemia

Wei Xu, MD PhD, Yongping Song, MD, Tingyu Wang, Shenmiao Yang, Lihong Liu, MD, Yu Hu, MD, Wei Zhang, Jianfeng Zhou, MD PhD, Sujun Gao, Kaiyang Ding, Huilai Zhang, MD PhD, Zunmin Zhu, MD, Shun-Qing Wang, Bing Xu, MD PhD, Jianda Hu, Ting Liu, MD PhD, Chunyan Ji, MD, Zhongjun Xia, MDPhD, Yan Li, PhDMD, Xin Wang, MDPhD, Huaqiang Zhu, MD, Renbin Zhao, PhD, Bin Zhang, PhD, Zhixin Xu, MD PhD, Jianyong Li, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-134531
Published: 2020
Journal Articles

Comparison of Subcutaneous Injection Versus Intravenous Infusion of Cytarabine for Induction Therapy in Young Adult Acute Myeloid Leukemia: Results of a Prospective, Multicenter, Noninferiority, Randomized Trial

Huafeng Wang, MD, LU LIU, MD, Jianfeng Zhou, MD PhD, Jianyong Li, MD PhD, Ying Lu, MD, Jianping Shen, MD, Chunyan Ji, MD, Tong Chen, MD PhD, Kang Yu, MD, Hanyun Ren, MD, Yan Li, MD, Dengju Li, MD, Ying Chen, MD, Shaolei Zang, MD, Bin Liang, MD, Sijing Kang, MD, Jinghan Wang, MDPhD, Wei Cheng, PhD, Haitao Meng, MD PhD, Wen-Juan Yu, Yanhong Tong, Honghu Zhu, MD, Jie Jin, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4.
https://doi.org/10.1182/blood-2020-143426
Published: 2020
Journal Articles

Entecavir prophylaxis for hepatitis B virus reactivation in patients with CAR T-cell therapy

Clinical Trials & Observations
Wenyue Cao, Jia Wei, Na Wang, Hao Xu, Min Xiao, Lifang Huang, Yang Cao, Chunrui Li, Yi Xiao, Chaojiang Gu, Shangkun Zhang, Dengju Li, Yichen Zhang, Tongcun Zhang, Jianfeng Zhou, Liang Huang
Journal: Blood
Blood (2020) 136 (4): 516–519.
https://doi.org/10.1182/blood.2020004907
Published: 2020
Includes: Supplemental data
Journal Articles

Efficacy and safety of CAR19/22 T-cell cocktail therapy in patients with refractory/relapsed B-cell malignancies

Clinical Trials & Observations
Na Wang, Xuelian Hu, Wenyue Cao, Chunrui Li, Yi Xiao, Yang Cao, Chaojiang Gu, Shangkun Zhang, Liting Chen, Jiali Cheng, Gaoxiang Wang, Xiaoxi Zhou, Miao Zheng, Xia Mao, Lijun Jiang, Di Wang, Qiuxiang Wang, Yaoyao Lou, Haodong Cai, Dandan Yan, Yicheng Zhang, Tongcun Zhang, Jianfeng Zhou, Liang Huang
Journal: Blood
Blood (2020) 135 (1): 17–27.
https://doi.org/10.1182/blood.2019000017
Published: 2020
Includes: Supplemental data