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Journal Articles

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Chen Wang, MD, Weinan Wang, BS, Lei Huang, PhD, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-140769

Published: 2020

Journal Articles

Myelodysplastic Syndromes-Associated Gene Mutations Lead to Pseudohypoxia Condition and Epigenome Hyper-Methylation in Mouse Genetic Models

Asumi Yokota, PhD, Lulu Zhang, PhD, Jianhua Feng, Xiaomin Feng, MD PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD

Blood (2019) 134 (Supplement_1): 1696.

https://doi.org/10.1182/blood-2019-126799

Published: 2019

Journal Articles

This Is a Title in Title Case: Prediction of CML Evolution By Telomere Length Analysis at the Single-Chromosome Level

Jingyuan Lu, Yingxing Zhou, Xiaomei Yan, Quanyi Lu

Blood (2019) 134 (Supplement_1): 2937.

https://doi.org/10.1182/blood-2019-126895

Published: 2019

Journal Articles

Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL

Chen Wang, PhDcandidate, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD

Blood (2018) 132 (Supplement 1): 1325.

https://doi.org/10.1182/blood-2018-99-116919

Published: 2018

Journal Articles

Myc Regulates the Development and Anti-Tumor Immunity of Natural Killer Cells

Yuting Tang, MD PhD, Xiaomei Yan, MD PhD, Di Zhan, PhD, Lijun Wen, MS, Rui Huang, MD PhD, Yue Zhang, MD PhD, Yoshihiro Hayashi, MD PhD, Qianfei Wang, PhD, Jianfeng Zhou, MD PhD, Gang Huang, PhD

Blood (2018) 132 (Supplement 1): 1113.

https://doi.org/10.1182/blood-2018-99-114180

Published: 2018

Journal Articles

Mll -Partial Tandem Duplication ( Mll -PTD) Causes Pseudohypoxia and Hypermethylation of the Epigenome through Suppression of Mitochondrial Complex II

Asumi Yokota, PhD, Lulu Zhang, PhD, Xiaomei Yan, MD PhD, Xiaomin Feng, MD PhD, Lijun Wen, MS, George Freudiger, Maria Rife, Ally Woeste, Yoshihiro Hayashi, MD PhD, Gang Huang, PhD

Blood (2018) 132 (Supplement 1): 1311.

https://doi.org/10.1182/blood-2018-99-112529

Published: 2018

Journal Articles

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Blood (2017) 130 (Supplement 1): 3565.

https://doi.org/10.1182/blood.V130.Suppl_1.3565.3565

Published: 2017

Journal Articles

Essential Role of c-MYC for Natural Killer Cell Development, Proliferation and Anti-Tumor Activity

Yuting Tang, MD, Xiaomei Yan, Rui Huang, MD PhD, Yoshihiro Hayashi, MD PhD, Yue Zhang, Wang Qianfei, PhD, Jianfeng Zhou, MD PhD, Gang Huang, PhD

Blood (2017) 130 (Supplement 1): 786.

https://doi.org/10.1182/blood.V130.Suppl_1.786.786

Published: 2017

Journal Articles

Monotcytes/Macrophages Are Involved in Erythrocytosis Caused By Both EPO-Dependent and -Independent Activation of EPOR

Asumi Yokota, PhD, Yoshihiro Hayashi, MD PhD, Jieyu Wang, MD PhD, Rui Huang, MD PhD, Xiaomei Yan, Yue Zhang, MD PhD, Gang Huang, PhD

Blood (2017) 130 (Supplement 1): 449.

https://doi.org/10.1182/blood.V130.Suppl_1.449.449

Published: 2017

Journal Articles

Global Crosstalk between Two Histone Modifications That Control Transcriptional Elongation in MLL Leukemia

Jiachen Bu, Aili Chen, PhD, Xiaomei Yan, Fuhong He, PhD, Yunzhu Dong, Yile Zhou, Jianlin He, Yoshihiro Hayashi, Di Zhan, Yanling Sun, Yue Zhang, Zhijian Xiao, Lee Grimes, Qianfei Wang, PhD, Gang Huang, PhD

Blood (2017) 130 (Supplement 1): 2495.

https://doi.org/10.1182/blood.V130.Suppl_1.2495.2495

Published: 2017

Journal Articles

The High NRF2 Expression Confers Chemotherapy Resistance through Upregulated DUSP1 in Myelodysplastic Syndromes

Peipei Lin, Yanling Ren, Xinping Zhou, Chen Mei, Chao Hu, Yingwan Luo, Yile Zhou, Xiaomei Yan, Gang Huang, PhD, Hongyan Tong, PhD

Blood (2017) 130 (Supplement 1): 2956.

https://doi.org/10.1182/blood.V130.Suppl_1.2956.2956

Published: 2017

Journal Articles

Downregulation of SETD2-H3K36me3 Tumor Suppression Axis Promotes MLL Leukemia through Activation of DOT1L-H3K79me2 Axis

Jiachen Bu, Aili Chen, PhD, Yunzhu Dong, PhD, Fuhong He, PhD, Xiaomei Yan, MD PhD, Yile Zhou, Di Zhan, Yoshihiro Hayashi, MD PhD, Qianfei Wang, PhD, Gang Huang, PhD

Blood (2016) 128 (22): 435.

https://doi.org/10.1182/blood.V128.22.435.435

Published: 2016

Journal Articles

SETD2, a H3K36 Lysine Methyltransferase, Is Essential for Adult Normal Hematopoiesis and Leukemia Stem Cells

Yile Zhou, Yunzhu Dong, Jiachen Bu, Xiaomei Yan, MD PhD, Yoshihiro Hayashi, MD PhD, Qianfei Wang, PhD, Jie Jin, MD PhD, Gang Huang, PhD

Blood (2016) 128 (22): 1055.

https://doi.org/10.1182/blood.V128.22.1055.1055

Published: 2016

Journal Articles

EPO Signaling Triggers Erythrocytosis By Expanding Erythrocytes and Also Subsets of Macrophages

Yoshihiro Hayashi, MD PhD, Jieyu Wang, MD, Zefeng Xu, MD, Xiaomei Yan, MD PhD, Yue Zhang, MD, Theodosia A Kalfa, MD PhD, Zhijian Xiao, MD, Gang Huang, PhD

Blood (2016) 128 (22): 542.

https://doi.org/10.1182/blood.V128.22.542.542

Published: 2016

Journal Articles

Activation of HIF Signaling in Mononuclear Phagocyte System Causes Hemophagocytic Lymphohistiocytosis in C57/BL6 Mice

Rui Huang, PhD , MD, Yoshihiro Hayashi, PhD, MD, Xiaomei Yan, PhD, MD, Michael Jordan, MD, Gang Huang, PhD

Blood (2016) 128 (22): 3675.

https://doi.org/10.1182/blood.V128.22.3675.3675

Published: 2016

Journal Articles

Two Novel Knock-in and Knock-out of Setd2 Alleles Cooperate with Mll-Af9 Knock-in Allele to Accelerate Leukemia Development

Yunzhu Dong, Yoshihiro Hayashi, MD PhD, Xiaomei Yan, MD PhD, Feng Xue, PhD, Wei Chen, PhD, Gang Huang, PhD

Blood (2015) 126 (23): 555.

https://doi.org/10.1182/blood.V126.23.555.555

Published: 2015

Journal Articles

Activation of HIF-2a-EPO Axis in Kidney or Liver Is Sufficient to Drive Erythrocytosis in a Novel Inducible HIF-2a Transgenic Mouse Model

Jieyu Wang, MD, Yoshihiro Hayashi, MD PhD, Zefeng Xu, MD, Lingyun Wu, MD PhD, Xiaomei Yan, MD PhD, Theodosia A. Kalfa, MD PhD, Zhijian Xiao, MD, Gang Huang, PhD

Blood (2015) 126 (23): 931.

https://doi.org/10.1182/blood.V126.23.931.931

Published: 2015

Journal Articles

HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development

Blood (2015) 126 (23): 303.

https://doi.org/10.1182/blood.V126.23.303.303

Published: 2015

Journal Articles

RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development

Blood (2014) 124 (21): 2187.

https://doi.org/10.1182/blood.V124.21.2187.2187

Published: 2014

Journal Articles

Novel Myelodysplastic Syndromes-like Mouse Models By Cooperating Genetic/Epigenetic Mutations Reveal the Critical Role of HIF-1α for Disease Development

Yoshihiro Hayashi, MD PhD, Yue Zhang, MD, Xiaomei Yan, MD PhD, Goro Sashida, MD PhD, Zefeng Xu, MD, Yunzhu Dong, Hironori Harada, MD PhD, Zhijian Xiao, MD, Gang Huang, PhD

Blood (2014) 124 (21): 362.

https://doi.org/10.1182/blood.V124.21.362.362

Published: 2014

NARROW

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Myelodysplastic Syndromes-Associated Gene Mutations Lead to Pseudohypoxia Condition and Epigenome Hyper-Methylation in Mouse Genetic Models

This Is a Title in Title Case: Prediction of CML Evolution By Telomere Length Analysis at the Single-Chromosome Level

Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL

Myc Regulates the Development and Anti-Tumor Immunity of Natural Killer Cells

Mll -Partial Tandem Duplication ( Mll -PTD) Causes Pseudohypoxia and Hypermethylation of the Epigenome through Suppression of Mitochondrial Complex II

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Essential Role of c-MYC for Natural Killer Cell Development, Proliferation and Anti-Tumor Activity

Monotcytes/Macrophages Are Involved in Erythrocytosis Caused By Both EPO-Dependent and -Independent Activation of EPOR

Global Crosstalk between Two Histone Modifications That Control Transcriptional Elongation in MLL Leukemia

The High NRF2 Expression Confers Chemotherapy Resistance through Upregulated DUSP1 in Myelodysplastic Syndromes

Downregulation of SETD2-H3K36me3 Tumor Suppression Axis Promotes MLL Leukemia through Activation of DOT1L-H3K79me2 Axis

SETD2, a H3K36 Lysine Methyltransferase, Is Essential for Adult Normal Hematopoiesis and Leukemia Stem Cells

EPO Signaling Triggers Erythrocytosis By Expanding Erythrocytes and Also Subsets of Macrophages

Activation of HIF Signaling in Mononuclear Phagocyte System Causes Hemophagocytic Lymphohistiocytosis in C57/BL6 Mice

Two Novel Knock-in and Knock-out of Setd2 Alleles Cooperate with Mll-Af9 Knock-in Allele to Accelerate Leukemia Development

Activation of HIF-2a-EPO Axis in Kidney or Liver Is Sufficient to Drive Erythrocytosis in a Novel Inducible HIF-2a Transgenic Mouse Model

HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development

RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development

Novel Myelodysplastic Syndromes-like Mouse Models By Cooperating Genetic/Epigenetic Mutations Reveal the Critical Role of HIF-1α for Disease Development

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American Society of Hematology

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ASH Publications

American Society of Hematology

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