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Journal Articles

Base Editing Repairs the HbE Mutation Restoring the Production of Normal Globin Chains in Severe HbE/β-Thalassemia Patient Hematopoietic Stem Cells and Erythroid Cells

Mohsin Badat, Peng Hua, Sachith Mettananda, Christopher Fisher, Noemi Roy, Siobhan Rice, Anindita Roy, Douglas R. Higgs, James Davies
Journal: Blood
Blood (2021) 138 (Supplement 1): 2935.
https://doi.org/10.1182/blood-2021-153283
Published: 2021
Journal Articles

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes

Brief Report
Peng Hua, Joanna Hester, George Adigbli, Rong Li, Bethan Psaila, Anindita Roy, Carole J. R. Bataille, Graham M. Wynne, Thomas Jackson, Thomas A. Milne, Angela J. Russell, James Davies, Irene Roberts, Fadi Issa, Suzanne M. Watt
Journal: Blood
Blood (2020) 136 (21): 2410–2415.
https://doi.org/10.1182/blood.2020005357
Published: 2020
Includes: Supplemental data
Journal Articles

Single-cell analysis of bone marrow–derived CD34 + cells from children with sickle cell disease and thalassemia

Peng Hua, Noemi Roy, Josu de la Fuente, Guanlin Wang, Supat Thongjuea, Kevin Clark, Anindita Roy, Bethan Psaila, Neil Ashley, Yvonne Harrington, Claus Nerlov, Suzanne M. Watt, Irene Roberts, James O. J. Davies
Journal: Blood
Blood (2019) 134 (23): 2111–2115.
https://doi.org/10.1182/blood.2019002301
Published: 2019
Includes: Supplemental data
Journal Articles

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Sorcha O’Byrne, Natalina Elliott, Siobhan Rice, Gemma Buck, Nicholas Fordham, Catherine Garnett, Laura Godfrey, Nicholas T. Crump, Gary Wright, Sarah Inglott, Peng Hua, Bethan Psaila, Benjamin Povinelli, David J. H. F. Knapp, Antonio Agraz-Doblas, Clara Bueno, Ignacio Varela, Phillip Bennett, Hashem Koohy, Suzanne M. Watt, Anastasios Karadimitris, Adam J. Mead, Phillip Ancliff, Paresh Vyas, Pablo Menendez, Thomas A. Milne, Irene Roberts, Anindita Roy
Journal: Blood
Blood (2019) 134 (13): 1059–1071.
https://doi.org/10.1182/blood.2019001289
Published: 2019
Includes: Supplemental data
Journal Articles

Does Osteogenic Potential of Clonal Human Bone Marrow Mesenchymal Stem/Stromal Cells Correlate with Their Vascular Supportive Ability?

Suzanne M Watt, PhDFRCPath, Alison Merryweather-Clarke, PhD, David Cook, PhD, Barbara Joo Lara, BSc, MRes, Emmanouela Repapi, PhD, Neil Ashley, PhD, Peng Hua, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4948.
https://doi.org/10.1182/blood.V130.Suppl_1.4948.4948
Published: 2017
Journal Articles

Molecular Insights at the Single Cell Level into the Reprogramming of Human Hematopoietic Stem Cells during Epigenetically Modified Ex Vivo Expansion

Peng Hua, PhD, Barbara Kronsteiner, PhD, Neil Ashley, PhD, Mark van der Garde, PhD, Diana Hernandez, PhD, Marina Tarunina, PhD, Lilian Hook, PhD, Yen Choo, PhD, Irene Roberts, MD, Adam J Mead, MD PhD, Suzanne M Watt, PhDFRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 2425.
https://doi.org/10.1182/blood.V130.Suppl_1.2425.2425
Published: 2017