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James Davies
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Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R Costa, David O'Connor, Rachael Pocock, Tanya Rapoz-D'Silva, Adam Turna, Lingyi Wang, Soo Wah Lee, Adele K Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R Hughes, James Davies, Alejandro Gutierrez, Michelle Kelliher, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood blood.2024024300.
https://doi.org/10.1182/blood.2024024300
Published: 2024
Includes: Supplemental data
Journal Articles

Base Editing Repairs the HbE Mutation Restoring the Production of Normal Globin Chains in Severe HbE/β-Thalassemia Patient Hematopoietic Stem Cells and Erythroid Cells

Mohsin Badat, Peng Hua, Sachith Mettananda, Christopher Fisher, Noemi Roy, Siobhan Rice, Anindita Roy, Douglas R. Higgs, James Davies
Journal: Blood
Blood (2021) 138 (Supplement 1): 2935.
https://doi.org/10.1182/blood-2021-153283
Published: 2021
Journal Articles

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes

Brief Report
Peng Hua, Joanna Hester, George Adigbli, Rong Li, Bethan Psaila, Anindita Roy, Carole J. R. Bataille, Graham M. Wynne, Thomas Jackson, Thomas A. Milne, Angela J. Russell, James Davies, Irene Roberts, Fadi Issa, Suzanne M. Watt
Journal: Blood
Blood (2020) 136 (21): 2410–2415.
https://doi.org/10.1182/blood.2020005357
Published: 2020
Includes: Supplemental data
Journal Articles

Dynamics and Mechanics Of KLF1 Regulation In Erythropoiesis

Kevin R. Gillinder, BSc PhD, Jim R. Hughes, Michael R. Tallack, BSc PhD, Graham Magor, BSc, Melissa Ilsley, BSc, James Davies, MD, Douglas Higgs, Andrew C. Perkins, MB BS PhD
Journal: Blood
Blood (2013) 122 (21): 2176.
https://doi.org/10.1182/blood.V122.21.2176.2176
Published: 2013