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Sarah Whelan
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Journal Articles

Molecular and structural basis of pan-resistance to BTK targeting therapies via BTK A428D mutation

Free
Quinlan Sievers, Hao Lu, Allison Cool, Stefan Gajewski, Tim Kong, Mark Noviski, Emel Ficici, Ratul Mukerji, James Iuliano, Jordan Ye, Mateo Sanchez Garcia de los Rios, Hugo Bousquet, Sarah Whelan, May Tan, Chris Phelps, Xiaoli Mi, Jahan Rahman, Samantha Sekeres, Erica Lamkin, Eduardo Bravo, Mark Ewalt, Anthony Mato, Lindsey Roeker, Justin Taylor, Meghan Thompson, Gwenn Hansen, Omar Abdel-Wahab
Journal: Blood
Blood (2025) 146 (Supplement 1): 2102.
https://doi.org/10.1182/blood-2025-2102
Published: 2025
Journal Articles

Nx-2127 and Nx-5948, Two Clinical Stage Cereblon-Recruiting BTK Degraders, Facilitate T Cell Functionality in Chronic Lymphocytic Leukemia

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Tiana Huynh, Sonia Rodriguez-Rodriguez, Carly Roleder, Sarah Whelan, May Tan, Ernestine Lee, Paul Munson, Alexey V. Danilov
Journal: Blood
Blood (2024) 144 (Supplement 1): 77.
https://doi.org/10.1182/blood-2024-204184
Published: 2024
Journal Articles

A First-in-Human Phase 1 Trial of NX-1607, a First-in-Class Oral CBL-B Inhibitor, in Patients with Advanced Malignancies Including DLBCL

Free
Graham P. Collins, William Townsend, Ahmed Abdulgawad, Swathi Namburi, Anja Williams, Ana Filipa Palma DosReis, Matthew G. Krebs, Jeff Evans, Sarah P. Blagden, Ruth Plummer, Daniel Hochhauser, Adam Sharp, George Cole, Seema Rogers, Daniel Chan, Sarah Whelan, Dima El-Sharkawi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3093.
https://doi.org/10.1182/blood-2023-172875
Published: 2023