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Journal Articles

Next-Generation Sequencing (NGS) for Residual Disease (MRD) Monitoring in T-Lymphoblastic Leukemia (T-ALL)

Ntasha Roy, Zhengwei (Jenny) Mao, Chang Xu, David T. Teachey, Zhiguo (Bruce) Chen, Meenakshi Devidas, Xueyan Chen, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Brent L. Wood
Journal: Blood
Blood (2023) 142 (Supplement 1): 2976.
https://doi.org/10.1182/blood-2023-190624
Published: 2023
Journal Articles

Treatment Outcomes for Adults with Mixed Phenotypic Acute Leukemia: A Large Single-Center Retrospective Study

Jennifer J. Huang, Jacob S. Appelbaum, Kathryn Russell, Carole Shaw, Ashley M. Eckel, Xueyan Chen, Rutu D. Vyas, Paul C. Hendrie, Anna B. Halpern, Raya Mawad, Ryan D Cassaday, Roland B. Walter, Mary-Elizabeth M. Percival, Cristina Maria Ghiuzeli
Journal: Blood
Blood (2023) 142 (Supplement 1): 2838.
https://doi.org/10.1182/blood-2023-188461
Published: 2023
Journal Articles

Single-Cell Multiomics for Residual Disease Detection in Acute Myelogenous Leukemia after Allogeneic Hematopoietic Cell Transplantation

Melinda Ann Biernacki, Olivia Waltner, Sami B Kanaan, Rula Green Gladden, Shruti Bhise, Todd M. Cooper, Monica Thakar, Soheil Meshinchi, Marie Bleakley, Xueyan Chen, Scott N Furlan
Journal: Blood
Blood (2022) 140 (Supplement 1): 10215–10216.
https://doi.org/10.1182/blood-2022-171164
Published: 2022
Journal Articles

Myeloid/Lymphoid Neoplasm with Eosinophilia and a Novel RUFY1-Pdgfrb Rearrangement

Karly Williams Silva, Carrie L. Cummings, Nahid Rashid, Olga Sala-Torra, Xueyan Chen, Yajuan J. Liu, Vivian G. Oehler
Journal: Blood
Blood (2021) 138 (Supplement 1): 4639.
https://doi.org/10.1182/blood-2021-151703
Published: 2021
Journal Articles

Myelodysplastic Syndrome with Excess Blasts and Secondary Acute Myeloid Leukemia: Same Disease with Different Blast Count

Xueyan Chen, MD, Megan Othus, PhD, Brent L Wood, MD PhD, Roland B. Walter, MD PhD MS, Pamela S. Becker, MD PhD, Mary-Elizabeth M. Percival, MD, Janis L. Abkowitz, MD, Frederick R. Appelbaum, MD, Elihu H. Estey, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2692.
https://doi.org/10.1182/blood-2019-124977
Published: 2019
Journal Articles

Comprehensive Evaluation and Validation of a Next-Generation Sequencing Assay for Minimal Residual Disease Detection in T-Lymphoblastic Leukemia/Lymphoma

Chang Xu, Ally Studer, Xueyan Chen, MD, Eric Hoyle, David Wu, MD PhD, Zhengwei Mao, Brent L Wood, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1475.
https://doi.org/10.1182/blood-2019-131360
Published: 2019
Journal Articles

The response to lymphodepletion impacts PFS in patients with aggressive non-Hodgkin lymphoma treated with CD19 CAR T cells

Clinical Trials & Observations
Alexandre V. Hirayama, Jordan Gauthier, Kevin A. Hay, Jenna M. Voutsinas, Qian Wu, Ted Gooley, Daniel Li, Sindhu Cherian, Xueyan Chen, Barbara S. Pender, Reed M. Hawkins, Aesha Vakil, Rachel N. Steinmetz, Utkarsh H. Acharya, Ryan D. Cassaday, Aude G. Chapuis, Tejaswini M. Dhawale, Paul C. Hendrie, Hans-Peter Kiem, Ryan C. Lynch, Jorge Ramos, Mazyar Shadman, Brian G. Till, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle
Journal: Blood
Blood (2019) 133 (17): 1876–1887.
https://doi.org/10.1182/blood-2018-11-887067
Published: 2019
Includes: Supplemental data
Journal Articles

Factors associated with durable EFS in adult B-cell ALL patients achieving MRD-negative CR after CD19 CAR T-cell therapy

Clinical Trials & Observations
Kevin A. Hay, Jordan Gauthier, Alexandre V. Hirayama, Jenna M. Voutsinas, Qian Wu, Daniel Li, Ted A. Gooley, Sindhu Cherian, Xueyan Chen, Barbara S. Pender, Reed M. Hawkins, Aesha Vakil, Rachel N. Steinmetz, Gary Schoch, Aude G. Chapuis, Brian G. Till, Hans-Peter Kiem, Jorge D. Ramos, Mazyar Shadman, Ryan D. Cassaday, Utkarsh H. Acharya, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle
Journal: Blood
Blood (2019) 133 (15): 1652–1663.
https://doi.org/10.1182/blood-2018-11-883710
Published: 2019
Includes: Supplemental data
Journal Articles

Multivariable Modeling of Disease and Treatment Characteristics of Adults with B-ALL in MRD-Negative CR after CD19 CAR-T Cells Identifies Factors Impacting Disease-Free Survival

Kevin A. Hay, MDFRCPC,MSc, Jordan Gauthier, MD, Alexandre V. Hirayama, MD, Jenna M. Voutsinas, MSc, Qian V. Wu, PhD, Daniel Li, PhD, Ted Gooley, PhD, Alyssa Sheih, PhD, Janaki Purushe, PhD, Sindhu Cherian, MD, Xueyan Chen, MD, Barbara S. Pender, MSc, Reed M. Hawkins, BS, Aesha Vakil, MSc, Rachel N. Steinmetz, BS, Tinh-Doan Phi, BS, Aude G. Chapuis, MD, Brian G. Till, MD, Hans-Peter Kiem, MD PhD, Jorge Ramos, DO, Mazyar Shadman, MD MPH, Ryan D. Cassaday, MD, Utkarsh H. Acharya, DO, Stanley R. Riddell, MD, David G. Maloney, MD PhD, Cameron J. Turtle, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 281.
https://doi.org/10.1182/blood-2018-99-110561
Published: 2018
Journal Articles

Efficacy and Toxicity of JCAR014 in Combination with Durvalumab for the Treatment of Patients with Relapsed/Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

Alexandre V. Hirayama, MD, Jordan Gauthier, MD, Kevin A. Hay, MDFRCPC,MSc, Alyssa Sheih, PhD, Sindhu Cherian, MD, Xueyan Chen, MD, Barbara S. Pender, MSc, Reed M. Hawkins, BS, Aesha Vakil, MSc, Rachel N. Steinmetz, BS, Tinh-Doan Phi, BS, Aude G. Chapuis, MD, Brian G. Till, MD, Hans-Peter Kiem, MD PhD, Mazyar Shadman, MD MPH, Ryan D. Cassaday, MD, Utkarsh H. Acharya, DO, Stanley R. Riddell, MD, David G. Maloney, MD PhD, Cameron J. Turtle, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1680.
https://doi.org/10.1182/blood-2018-99-116745
Published: 2018
Journal Articles

Factors Impacting Progression-Free Survival after CD19-Specific CAR-T Cell Therapy for Relapsed/Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

Alexandre V. Hirayama, MD, Jordan Gauthier, MD, Kevin A. Hay, MDFRCPC,MSc, Jenna M. Voutsinas, MSc, Qian V. Wu, PhD, Ted Gooley, PhD, Daniel Li, PhD, Alyssa Sheih, PhD, Janaki Purushe, PhD, Sindhu Cherian, MD, Xueyan Chen, MD, Barbara S. Pender, MSc, Reed M. Hawkins, BS, Aesha Vakil, MSc, Rachel N. Steinmetz, BS, Tinh-Doan Phi, BS, Ryan C. Lynch, MD, Aude G. Chapuis, MD, Brian G. Till, MD, Hans-Peter Kiem, MD PhD, Jorge Ramos, DO, Mazyar Shadman, MD MPH, Ryan D. Cassaday, MD, Utkarsh H. Acharya, DO, Stanley R. Riddell, MD, David G. Maloney, MD PhD, Cameron J. Turtle, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1681.
https://doi.org/10.1182/blood-2018-99-115126
Published: 2018
Journal Articles

Infectious complications of CD19-targeted chimeric antigen receptor–modified T-cell immunotherapy

Clinical Trials & Observations
Joshua A. Hill, Daniel Li, Kevin A. Hay, Margaret L. Green, Sindhu Cherian, Xueyan Chen, Stanley R. Riddell, David G. Maloney, Michael Boeckh, Cameron J. Turtle
Journal: Blood
Blood (2018) 131 (1): 121–130.
https://doi.org/10.1182/blood-2017-07-793760
Published: 2018
Includes: Supplemental data
Journal Articles

Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy

Clinical Trials & Observations
Kevin A. Hay, Laïla-Aïcha Hanafi, Daniel Li, Juliane Gust, W. Conrad Liles, Mark M. Wurfel, José A. López, Junmei Chen, Dominic Chung, Susanna Harju-Baker, Sindhu Cherian, Xueyan Chen, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle
Journal: Blood
Blood (2017) 130 (21): 2295–2306.
https://doi.org/10.1182/blood-2017-06-793141
Published: 2017
Includes: Supplemental data
Journal Articles

Addition of Fludarabine to Cyclophosphamide Lymphodepletion Improves In Vivo Expansion of CD19 Chimeric Antigen Receptor-Modified T Cells and Clinical Outcome in Adults with B Cell Acute Lymphoblastic Leukemia

Cameron J Turtle, MBBS, PhD, Laila-Aicha Hanafi, PhD, Carolina Berger, MD, Daniel Sommermeyer, PhD, Barbara Pender, MS, Emily M Robinson, BS, Katherine Melville, Tanya M Budiarto, BSc, Natalia N Steevens, Colette Chaney, RN, Sindhu Cherian, MD, Brent L Wood, MD PhD, Lorinda Soma, MD, Xueyan Chen, MD PhD, Shelly Heimfeld, PhD, Michael C Jensen, MD, Stanley R. Riddell, MD, David G Maloney, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3773.
https://doi.org/10.1182/blood.V126.23.3773.3773
Published: 2015
Journal Articles

Anti-CD19 Chimeric Antigen Receptor-Modified T Cell Therapy for B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia: Fludarabine and Cyclophosphamide Lymphodepletion Improves In Vivo Expansion and Persistence of CAR-T Cells and Clinical Outcomes

Cameron J Turtle, MBBS, PhD, Carolina Berger, MD, Daniel Sommermeyer, PhD, Laila-Aicha Hanafi, PhD, Barbara Pender, MS, Emily M Robinson, BS, Katherine Melville, Tanya M Budiarto, BSc, Natalia N Steevens, Colette Chaney, RN, Sindhu Cherian, MD, Brent L Wood, MD PhD, Lorinda Soma, MD, Xueyan Chen, MD PhD, Shelly Heimfeld, PhD, Michael C Jensen, MD, Stanley R. Riddell, MD, David G Maloney, MD PhD
Journal: Blood
Blood (2015) 126 (23): 184.
https://doi.org/10.1182/blood.V126.23.184.184
Published: 2015
Journal Articles

Immunophenotypic Features of Myeloid Stem Cell Neoplasms Associated with Monosomy 7

Xueyan Chen, MD PhD, Sindhu Cherian, MD
Journal: Blood
Blood (2014) 124 (21): 1051.
https://doi.org/10.1182/blood.V124.21.1051.1051
Published: 2014
Journal Articles

The Relation of Clinical Response and Minimal Residual Disease and Their Prognostic Impact On Outcome in Acute Myeloid Leukemia

Xueyan Chen, MD, PhD, Hu Xie, Carl Bohm, Brent L. Wood, MD, PhD, John M. Pagel, MD, PhD, Pamela S. Becker, MD, PhD, Roland B. Walter, MD, PhD, Ravinder K Sandhu, MD, Janis L Abkowitz, MD, Frederick R. Appelbaum, MD, Elihu H. Estey, MD
Journal: Blood
Blood (2012) 120 (21): 1418.
https://doi.org/10.1182/blood.V120.21.1418.1418
Published: 2012