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Gunes Gundem
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Journal Articles

Diagnostic Utility of Comprehensive RNA-Seq Analysis in Adult B-ALL

Noushin Farnoud, Konstantinos Liosis, Daniel Leongamornlert, Jesús Gutiérrez-Abril, Juan E. Arango Ossa, Gunes Gundem, Anu Amallraja, Dylan Domenico, Joseph McCarter, Amy A Kirkwood, Laura Clifton-Hadley, Bela Patel Wrench, Anthony Moorman, Adele Kay Fielding, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 1601.
https://doi.org/10.1182/blood-2023-190519
Published: 2023
Journal Articles

A D e Novo Supernumerary Ring Chromosome 1 Causes B-Cell Acute Lymphoblastic Leukemia in Monozygotic Twins Due to Independent and Partially Convergent Evolutionary Trajectories

Jesús Gutiérrez-Abril, Gunes Gundem, Elise Fiala, Konstantinos Liosis, Noushin Farnoud, Daniel Leongamornlert, Anu Amallraja, Juan E. Arango Ossa, Dylan Domenico, Max F. Levine, Juan Santiago Medina Martinez, Michael F. Walsh, Sylwia Jasinski, Andrew L. Kung, Neerav N. Shukla, William L. Carroll, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 4352.
https://doi.org/10.1182/blood-2023-181194
Published: 2023
Journal Articles

Enhancing Myeloid Cancer Genomic Profiling through Comprehensive Whole Genome Sequencing Using the Isabl Gxt Heme Analytical Platform

Aditya S Deshpande, Max F. Levine, Kevin Hadi, Gunes Gundem, Minal Patel, Stan Skrzypczak, Andrew L. Kung, Juan S Medina-Martínez, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 3653.
https://doi.org/10.1182/blood-2023-182017
Published: 2023
Journal Articles

Unmatched Whole-Genome Sequencing As a Clinical Tool for Hematological Neoplasms with Significant Utility in Cases with Tumor-in-Normal Contamination

Jesús Gutiérrez-Abril, Daniel Leongamornlert, Neerav N Shukla, Maria Luisa Sulis, Yangyu Zhou, Max F. Levine, Emilio Barretta, SooWah Lee, Juan E. Arango-Ossa, Gunes Gundem, Juan S. Medina-Martínez, Bela Patel Wrench, Anthony V. Moorman, Adele K. Fielding, Andrew L. Kung, Elli Papaemmanuil
Journal: Blood
Blood (2022) 140 (Supplement 1): 1197–1199.
https://doi.org/10.1182/blood-2022-160322
Published: 2022
Journal Articles

Revealing the Impact of Recurrent and Rare Structural Variations in Multiple Myeloma

Even H Rustad, MD, Venkata Yellapantula, PhD, Dominik Glodzik, PhD, Gunes Gundem, PhD, Daniel A. Leongamornlert, PhD, Peter J Campbell, Elli Papaemmanuil, PhD, Ola Landgren, MD PhD, Francesco Maura, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 576.
https://doi.org/10.1182/blood-2019-126392
Published: 2019
Journal Articles

Whole Genome Sequencing of Extramedullary Myeloma Autopsy Tumors Reveals a Genomic Portrait at Culmination of Clonal Convergence

Venkata D Yellapantula, Even H Rustad, Dominik Glozdik, PhD, Gunes Gundem, PhD, Jun Fan, Juan Medina, MS, Akshar Patel, BA, Minal Patel, BA, Malin Hultcrantz, MD PhD, Jonathan U. Peled, MD, Nikoletta Lendvai, MD PhD, Ola Landgren, MD PhD, Sergio Giralt, MD, Christine Iacobuzio-Donahue, Elli Papaemmanuil, PhD, Heather J. Landau, MD, Alexander M. Lesokhin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3169.
https://doi.org/10.1182/blood-2018-99-118740
Published: 2018
Journal Articles

Early Detection and Molecular Characterization of Therapy-Related Leukemia in Children Reveals Patterns of Disease Transformation and Guides Future Surveillance Protocols

Barbara Spitzer, MD, Gunes Gundem, PhD, Noushin Farnoud, PhD, Nathan Millard, MD, Erin McGovern, BA, Minal Patel, BA, Max Levine, MS, Juan Medina, MS, Yangyu Zhou, BS, Juan E. Arango Ossa, BS, Michael Francis Walsh, MD, Ross L. Levine, MD, Irene Y. Cheung, ScD, Scott A. Armstrong, MD PhD, Nai-Kong V. Cheung, MD PhD, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 291.
https://doi.org/10.1182/blood-2018-99-120005
Published: 2018
Journal Articles

Oncologic Therapy for Solid Tumors Alters the Risk of Clonal Hematopoiesis

Kelly Bolton, MD PhD, Ryan Ptashkin, MS, Lior Braunstein, MD, Daniel Kelly, Sean M Devlin, PhD, Catherine C. Coombs, MD, Matahi Moarii, PhD, Minal Patel, BA, Elsa Bernard, PhD, Antonin Berthon, Dominik Glodzik, PhD, Michael Francis Walsh, MD, Diana Mandelker, MD PhD, Akshar Patel, BA, Jessica Schulman, Gunes Gundem, PhD, Choonsik Lee, PhD, Montserrat García-Closas, MD Dr.P.H, Stuart Gardos, Jose Baselga, MD, David M. Hyman, MD, Martin S. Tallman, MD, Howard Scher, MD, Dean Bajorin, MD, Mariko Yabe, MD PhD, Virginia M. Klimek, MD, Luis Alberto Diaz, MD, Nilanjan Chatterjee, PhD, Michael F. Berger, PhD, Lindsay M. Morton, PhD, Ross L. Levine, MD, Ahmet Zehir, PhD, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 747.
https://doi.org/10.1182/blood-2018-99-119530
Published: 2018
Journal Articles

A Knowledge-Based Approach for Clinical Annotation of Oncogenic Variants to Support Patient-Tailored Diagnosis in Myeloid Disease

Elsa Bernard, PhD, Kenichi Yoshida, MD PhD, Gunes Gundem, PhD, Jacob Grinfeld, MBChB, BSc, MRCP, FRCPath, Jyoti Nangalia, MBBChir, MA, MRCP, FRCPath, PhD, Daniel Leongamornlert, PhD, Noushin Farnoud, PhD, Juan Medina, Matahi Moarii, PhD, Charlie Massie, PhD, Yasunobu Nagata, MD PhD, Yusuke Okuno, MD PhD, Torsten Haferlach, MD, Seishi Ogawa, MD PhD, Amanda Gilkes, Oliver G. Ottmann, MD, Robert K. Hills, DPhil, Nigel H. Russell, Brian J.P Huntly, Anthony R Green, PhD FRCP, FRCPath, FMedSci, Alan K. Burnett, MD, Peter Campbell, PhD, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1414.
https://doi.org/10.1182/blood.V130.Suppl_1.1414.1414
Published: 2017
Journal Articles

Personalized Prognostic Predictions for Patients with Myeloproliferative Neoplasms through Integration of Comprehensive Genomic and Clinical Information

Jacob Grinfeld, MBChB, BSc, MRCP, FRCPath, Jyoti Nangalia, MBBChir, MA, MRCP, FRCPath, PhD, E Joanna Baxter, PhD, Anna L. Godfrey, BMBCh, PhD MRCP, FRCPath, Paola Guglielmelli, MD PhD, Rob Cantrill, PhD, David Wedge, PhD, Nicos Angelopoulos, PhD, Gunes Gundem, PhD, Charlie Massie, PhD, Elli Papaemmanuil, PhD, Cathy MacLean, BSc, MSc, MBA, Julia Cook, BSc, Francesca Lauren Nice, PhD MSc, Christen Lykkegaard Andersen, PhD, Hans Carl Hasselbalch, MD Professor, DMSc, Mary Frances McMullin, MB,Bch BAO, MD FRCPath, Alessandro M. Vannucchi, Claire N. Harrison, BMBCh, DM, FRCP, FRCPath, Moritz Gerstung, PhD, Peter J Campbell, MD PhD, Anthony R Green, PhD FRCP, FRCPath, FMedSci
Journal: Blood
Blood (2017) 130 (Supplement 1): 491.
https://doi.org/10.1182/blood.V130.Suppl_1.491.491
Published: 2017
Journal Articles

Clinical and biological implications of driver mutations in myelodysplastic syndromes

CME
Elli Papaemmanuil, Moritz Gerstung, Luca Malcovati, Sudhir Tauro, Gunes Gundem, Peter Van Loo, Chris J. Yoon, Peter Ellis, David C. Wedge, Andrea Pellagatti, Adam Shlien, Michael John Groves, Simon A. Forbes, Keiran Raine, Jon Hinton, Laura J. Mudie, Stuart McLaren, Claire Hardy, Calli Latimer, Matteo G. Della Porta, Sarah O’Meara, Ilaria Ambaglio, Anna Galli, Adam P. Butler, Gunilla Walldin, Jon W. Teague, Lynn Quek, Alex Sternberg, Carlo Gambacorti-Passerini, Nicholas C. P. Cross, Anthony R. Green, Jacqueline Boultwood, Paresh Vyas, Eva Hellstrom-Lindberg, David Bowen, Mario Cazzola, Michael R. Stratton, Peter J. Campbell
Journal: Blood
Blood (2013) 122 (22): 3616–3627.
https://doi.org/10.1182/blood-2013-08-518886
Published: 2013
Includes: Supplemental data
Journal Articles

The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients

Jyoti Nangalia, MBBChir FRCPath, Charles Massie, PhD, E Joanna Baxter, PhD, Francesca L Nice, MRes, Gunes Gundem, PhD, David Wedge, PhD, Edward Avezov, PhD, Juan Li, PhD, Karoline Kollmann, PhD, David G. Kent, PhD, Athar Aziz, PhD, Anna L Godfrey, BMBCh FRCPath, Jonathan Hinton, MSc, Inigo Martincorena, PhD, Peter Van Loo, PhD, Amy V Jones, PhD, Paola Guglielmelli, PhD MD, Patrick Tarpey, PhD, Heather P Harding, PhD, John D Fitzpatrick, BA, Calum T Goudie, BA, Christina A Ortmann, MD, Stephen J Loughran, PhD, Keiran Raine, MSc, David Jones, MSc, Adam Butler, MSc, Jon W Teague, MSc, Sarah O'Meara, Stuart McLaren, Michele Bianchi, Yvonne Silber, MSc, Danai Dimitropolou, BSc, David Bloxham, MSc FRCPath, Laura J Mudie, BSc, Mark Maddison, BSc, Ben Robinson, BSc, Clodagh Keohane, MD, Cathy MacLean, MSc, Kate Hill, BM BS, Kim H. Orchard, MBBS, PhD, FRCP, FRCPath, Sudhir Tauro, PhD, Ming-Qing Du, MB, PhD, Mel Greaves, PhD, FRS, David Bowen, MD, PhD, Brian Huntly, MBChB FRCPath PhD, Claire N Harrison, DM, FRCP, FRCPath, Nicholas C.P. Cross, PhD, FRCPath, David Ron, MD, Alessandro M Vannucchi, MD, Elli Papaemmanuil, PhD, Peter J. Campbell, PhD, Anthony R Green, FRCPath FMedSci
Journal: Blood
Blood (2013) 122 (21): LBA-2.
https://doi.org/10.1182/blood.V122.21.LBA-2.LBA-2
Published: 2013
Journal Articles

High Throughput Targeted Gene Sequencing in 738 Myelodysplastic Syndromes Patients Reveals Novel Oncogenic Genes, Rare Driver Mutations and Complex Molecular Signatures with Potential Impact for Patient Diagnosis and Prognosis in the Clinic

Elli Papaemmanuil, PhD, Moritz Gerstung, PhD, Luca Malcovati, MD, Sudhir Tauro, PhD, Gunes Gundem, PhD, Peter Van Loo, PhD, Andrea Pellagatti, PhD, Michael J Groves, PhD, Nick C.P. Cross, PhD, Carlo Gambacorti-Passerini, MD, Anthony R Green, MD, Jacqueline Boultwood, PhD, Paresh Vyas, MD, Eva Hellstrom-Lindberg, MD, David Bowen, MD, Mario Cazzola, MD, Michael R Stratton, MD, PhD, Peter Campbell, MD Phd
Journal: Blood
Blood (2012) 120 (21): LBA-5.
https://doi.org/10.1182/blood.V120.21.LBA-5.LBA-5
Published: 2012