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Journal Articles

Enhancing Myeloid Cancer Genomic Profiling through Comprehensive Whole Genome Sequencing Using the Isabl Gxt Heme Analytical Platform

Aditya S Deshpande, Max F. Levine, Kevin Hadi, Gunes Gundem, Minal Patel, Stan Skrzypczak, Andrew L. Kung, Juan S Medina-Martínez, Elli Papaemmanuil

Blood (2023) 142 (Supplement 1): 3653.

https://doi.org/10.1182/blood-2023-182017

Published: 2023

Journal Articles

A D e Novo Supernumerary Ring Chromosome 1 Causes B-Cell Acute Lymphoblastic Leukemia in Monozygotic Twins Due to Independent and Partially Convergent Evolutionary Trajectories

Jesús Gutiérrez-Abril, Gunes Gundem, Elise Fiala, Konstantinos Liosis, Noushin Farnoud, Daniel Leongamornlert, Anu Amallraja, Juan E. Arango Ossa, Dylan Domenico, Max F. Levine, Juan Santiago Medina Martinez, Michael F. Walsh, Sylwia Jasinski, Andrew L. Kung, Neerav N. Shukla, William L. Carroll, Elli Papaemmanuil

Blood (2023) 142 (Supplement 1): 4352.

https://doi.org/10.1182/blood-2023-181194

Published: 2023

Journal Articles

Effects of LSD1 Inhibition with Img-7289 on the Leukemia Initiating Cell Population with Induction of Differentiation and Cell Death in Pediatric Relapsed/Refractory AML

Jaclyn Rosenzweig, Diego Ferreira Coutinho, Matthew Long, Katie Souto, Glorymar Ibanez Sanchez, Raina Fishkin, Kristina Guillan, Armaan Siddiquee, Paul Calder, Daoqi You, Andrew L. Kung, Filemon Dela Cruz

Blood (2022) 140 (Supplement 1): 5944–5945.

https://doi.org/10.1182/blood-2022-165408

Published: 2022

Journal Articles

Unmatched Whole-Genome Sequencing As a Clinical Tool for Hematological Neoplasms with Significant Utility in Cases with Tumor-in-Normal Contamination

Jesús Gutiérrez-Abril, Daniel Leongamornlert, Neerav N Shukla, Maria Luisa Sulis, Yangyu Zhou, Max F. Levine, Emilio Barretta, SooWah Lee, Juan E. Arango-Ossa, Gunes Gundem, Juan S. Medina-Martínez, Bela Patel Wrench, Anthony V. Moorman, Adele K. Fielding, Andrew L. Kung, Elli Papaemmanuil

Blood (2022) 140 (Supplement 1): 1197–1199.

https://doi.org/10.1182/blood-2022-160322

Published: 2022

Journal Articles

Rabbit Anti-Thymocyte Globulin Exposure (rATG) in CD34+ Selected Hematopoietic Cell Transplantation and Its Impact on Immune Reconstitution and Outcomes in Children and Adults

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-136341

Published: 2020

Journal Articles

Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL

Blood (2019) 134 (26): 2361–2368.

https://doi.org/10.1182/blood.2019001641

Published: 2019

Includes: Supplemental data

Journal Articles

Exploiting an Asp-Glu "Switch" in Glycogen Synthase Kinase 3 to Design Paralog Selective Inhibitors for Acute Myeloid Leukemia Treatment

Blood (2017) 130 (Supplement 1): 2075.

https://doi.org/10.1182/blood.V130.Suppl_1.2075.2075

Published: 2017

Journal Articles

Brentuximab Vedotin Plus Bendamustine Is an Effective Salvage Regimen for Pediatric Patients with Relapsed Hodgkin Lymphoma

Nitya Gulati, MBBS, Farid Boulad, MD, Maria I. Cancio, MD, Kevin J. Curran, MD, Carolyn Jackson, Nancy Kernan, MD, Andrew L. Kung, MD PhD, Richard O'Reilly, MD, Susan Prockop, MD, Kavitha Ramaswamy, MD, Andromachi Scaradavou, MD, Barbara Spitzer, Neerav Shukla, MD, Peter G. Steinherz, MD, Christopher Forlenza

Blood (2017) 130 (Supplement 1): 5172.

https://doi.org/10.1182/blood.V130.Suppl_1.5172.5172

Published: 2017

Journal Articles

High Dose Cyclophosphamide and Pre-Treatment Disease Burden Dictate Response and Survival in a Multicenter Clinical Trial Using CD19-Specific CAR T Cells for Relapsed/Refractory B-ALL

Blood (2017) 130 (Supplement 1): 1326.

https://doi.org/10.1182/blood.V130.Suppl_1.1326.1326

Published: 2017

Journal Articles

Molecular Profiling of High-Risk Pediatric Acute Myeloid Leukemia

Lianna J Marks, MD, Jennifer A Oberg, EdD, Julia L Glade-Bender, MD, Susan J Hsiao, MD, Danielle Pendrick, MPH, Anthony N Sireci, MD, Stuart J Andrews, PhD, Mahesh M Mansukhani, MD, Andrew L. Kung, MD PhD, Maria Luisa Sulis, MD

Blood (2016) 128 (22): 5250.

https://doi.org/10.1182/blood.V128.22.5250.5250

Published: 2016

Journal Articles

Leukemia-Specific Delivery of Mutant NOTCH1 Targeted Therapy

Giovanni Roti, MD PhD, Jun Qi, PhD, Samuel Kitara, Anthony C. Varca, Marta Sanchez-Martin, PhD, Andrew L. Kung, MD PhD, Adolfo A. Ferrando, MD PhD, James E. Bradner, MD, Kimberly Stegmaier, MD

Blood (2016) 128 (22): 889.

https://doi.org/10.1182/blood.V128.22.889.889

Published: 2016

Journal Articles

Targeting MTHFD2 in Acute Myeloid Leukemia

Yana Pikman, MD, Alexandre Puissant, PhD, Gabriela Alexe, PhD, Andrew Furman, BA, Stacey Frumm, BA, Linda Ross, PhD, Liying Chen, PhD, Nina Fenouille, PhD, Christopher F. Bassil, BA, Caroline A Lewis, PhD, Richard M. Stone, MD, Daniel J. DeAngelo, MD PhD, Ilene Galinsky, ANP, Andrew L Kung, MD PhD, Matthew Vader Heiden, MD PhD, Michael T. Hemann, PhD, Versha Banerji, MD, Kimberly Stegmaier, MD

Blood (2015) 126 (23): 443.

https://doi.org/10.1182/blood.V126.23.443.443

Published: 2015

Journal Articles

Proxe: A Public Repository of Xenografts to Facilitate Studies of Biology and Expedite Preclinical Drug Development in Leukemia and Lymphoma

Mark A. Murakami, MD MA, Alexandra N. Christodoulou, M.S., Amanda L Christie, B.S., Tiffany DeSouza, B.S., Abner Louissaint, Jr., MD PhD, Una Vojinovic, B.S., Raphael Koch, MD, Loretta S. Li, MD, Scott P. Kallgren, PhD, Prakash Rao, PhD, Johannes Köster, PhD, Raga Vadhi, M.S., Eilene Duberow, B.S., Elizabeth A. Morgan, MD, Hongjun Wang, Samia S. Ahmed, Katharine L. Majewski, Marina Konopleva, MD PhD, Jerome Tamburini, MD, PhD, Alejandro Gutierrez, MD, Michelle Kelliher, PhD, Julia Etchin, PhD, Irmela Jeremias, MD, Andrew P. Weng, MD PhD, Andrew L Kung, MD PhD, Andrew A Lane, MD PhD, Francine Garnache-Ottou, PhD, Shai Izraeli, MD Prof, Eric Jacobsen, MD, Ilene Galinsky, ANP, Richard M. Stone, MD, Marian H. Harris, MD PhD, David M. Dorfman, MD PhD, Jon C Aster, MDPhD, Henry Long, PhD, Lewis B. Silverman, MD, David M Weinstock, MD

Blood (2015) 126 (23): 3252.

https://doi.org/10.1182/blood.V126.23.3252.3252

Published: 2015

Journal Articles

Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach

Atsushi Nonami, Martin Sattler, Ellen Weisberg, Qingsong Liu, Jianming Zhang, Matthew P. Patricelli, Amanda L. Christie, Amy M. Saur, Nancy E. Kohl, Andrew L. Kung, Hojong Yoon, Taebo Sim, Nathanael S. Gray, James D. Griffin

Blood (2015) 125 (20): 3133–3143.

https://doi.org/10.1182/blood-2014-12-615906

Published: 2015

Includes: Supplemental data

Journal Articles

Newer-Generation HSP90 Inhibitors Can Overcome Ibrutinib Resistance and Suppress Proliferation in Human Mantle Cell Lymphoma in Vitro and in Vivo

Nadja Kopp, MA, Sebastian Tschuri, Sarah Haebe, Diederik van Bodegom, PhD, Liat Bird, Amanda L. Christie, Amy Saur, Alexandra N. Christodoulou, Trevor Tivey, Andrew L Kung, MD PhD, Oliver Weigert, MD, David Weinstock, MD

Blood (2014) 124 (21): 1686.

https://doi.org/10.1182/blood.V124.21.1686.1686

Published: 2014

Journal Articles

Selective Inhibitor of Nuclear Export (SINE), Selinexor (KPT-330), Shows Remarkable Activity Against AML Leukemia-Initiating Cells

Julia Etchin, PhD, Bonnie Thi Le, M.S., Alex Kentsis, MD PhD, Marc R Mansour, MDPhD, Alla Berezovskaya, B.S., Richard M. Stone, MD, Ilene Galinsky, RNP, Daniel J. DeAngelo, MDPhD, Dilara McCauley, PhD, Michael Kauffman, MD PhD, Sharon Shacham, PhDMBA, Jean C.Y. Wang, MDPhD, Andrew L Kung, MD PhD, A. Thomas Look, MD

Blood (2014) 124 (21): 995.

https://doi.org/10.1182/blood.V124.21.995.995

Published: 2014

Journal Articles

Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma

Yu-Tzu Tai, Patrick A. Mayes, Chirag Acharya, Mike Y. Zhong, Michele Cea, Antonia Cagnetta, Jenny Craigen, John Yates, Louise Gliddon, William Fieles, Bao Hoang, James Tunstead, Amanda L. Christie, Andrew L. Kung, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson

Blood (2014) 123 (20): 3128–3138.

https://doi.org/10.1182/blood-2013-10-535088

Published: 2014

Includes: Supplemental data

Journal Articles

Targeting Oncogenic Interleukein-7 Receptor Signaling With N-Acetylcysteine In T-Cell Acute Lymphoblastic Leukemia

Marc R. Mansour, MD PhD FRCPath, Casie Reed, Amy Eisenberg, Jen-Chieh Tseng, PhD, Akinori Yoda, PhD, Scott J Rodig, MD, PhD, Daniel J. DeAngelo, MD, Ph.D, Stephen E. Sallan, MD, David M. Weinstock, MD, Shai Izraeli, MD, Andrew L Kung, MD, PhD, Alex Kentsis, MD, PhD, Thomas Look, MD

Blood (2013) 122 (21): 2535.

https://doi.org/10.1182/blood.V122.21.2535.2535

Published: 2013

Journal Articles

Novel Inhibitors Of CRM1/XPO1 Nuclear Exporter Exhibit Striking Activity Against AML “primagrafts,” Including AML Leukemia Initiating Cells, While Sparing Normal Hematopoietic Cells

Julia Etchin, PhD, Bonnie Thi Le, M.S., Alex Kentsis, MD, PhD, Richard M. Stone, MD, Dilara McCauley, PhD, Michael Kauffman, MD, PhD, Sharon Shacham, PhD, MBA, Jean C.Y. Wang, MD PhD, Andrew L Kung, MD, PhD, A. Thomas Look, MD

Blood (2013) 122 (21): 3932.

https://doi.org/10.1182/blood.V122.21.3932.3932

Published: 2013

Journal Articles

Disruption Of Super Enhancer-Driven Cancer Dependencies In Diffuse Large B-Cell Lymphoma

Bjoern Chapuy, MD, PhD, McKeown Michael, Charles Y. Lin, PhD, Stefano Monti, PhD, Margaretha GM Roemer, Jun Qi, Peter B. Rahl, PhD, Heather Sun, Kelly T. Yeda, Andrew L. Kung, MD, PhD, Scott J. Rodig, MD, PhD, Richard A. Young, PhD, Margaret A. Shipp, MD, James E. Bradner, MD

Blood (2013) 122 (21): 3021.

https://doi.org/10.1182/blood.V122.21.3021.3021

Published: 2013

NARROW

Enhancing Myeloid Cancer Genomic Profiling through Comprehensive Whole Genome Sequencing Using the Isabl Gxt Heme Analytical Platform

A D e Novo Supernumerary Ring Chromosome 1 Causes B-Cell Acute Lymphoblastic Leukemia in Monozygotic Twins Due to Independent and Partially Convergent Evolutionary Trajectories

Effects of LSD1 Inhibition with Img-7289 on the Leukemia Initiating Cell Population with Induction of Differentiation and Cell Death in Pediatric Relapsed/Refractory AML

Unmatched Whole-Genome Sequencing As a Clinical Tool for Hematological Neoplasms with Significant Utility in Cases with Tumor-in-Normal Contamination

Rabbit Anti-Thymocyte Globulin Exposure (rATG) in CD34+ Selected Hematopoietic Cell Transplantation and Its Impact on Immune Reconstitution and Outcomes in Children and Adults

Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL

Exploiting an Asp-Glu "Switch" in Glycogen Synthase Kinase 3 to Design Paralog Selective Inhibitors for Acute Myeloid Leukemia Treatment

Brentuximab Vedotin Plus Bendamustine Is an Effective Salvage Regimen for Pediatric Patients with Relapsed Hodgkin Lymphoma

High Dose Cyclophosphamide and Pre-Treatment Disease Burden Dictate Response and Survival in a Multicenter Clinical Trial Using CD19-Specific CAR T Cells for Relapsed/Refractory B-ALL

Molecular Profiling of High-Risk Pediatric Acute Myeloid Leukemia

Leukemia-Specific Delivery of Mutant NOTCH1 Targeted Therapy

Targeting MTHFD2 in Acute Myeloid Leukemia

Proxe: A Public Repository of Xenografts to Facilitate Studies of Biology and Expedite Preclinical Drug Development in Leukemia and Lymphoma

Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach

Newer-Generation HSP90 Inhibitors Can Overcome Ibrutinib Resistance and Suppress Proliferation in Human Mantle Cell Lymphoma in Vitro and in Vivo

Selective Inhibitor of Nuclear Export (SINE), Selinexor (KPT-330), Shows Remarkable Activity Against AML Leukemia-Initiating Cells

Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma

Targeting Oncogenic Interleukein-7 Receptor Signaling With N-Acetylcysteine In T-Cell Acute Lymphoblastic Leukemia

Novel Inhibitors Of CRM1/XPO1 Nuclear Exporter Exhibit Striking Activity Against AML “primagrafts,” Including AML Leukemia Initiating Cells, While Sparing Normal Hematopoietic Cells

Disruption Of Super Enhancer-Driven Cancer Dependencies In Diffuse Large B-Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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