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Emilia Kooienga
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Journal Articles

Sf3b1+/K700E hematopoietic stem cells create their own expansion niche

Free
Elodie Henriet, LaShanale Wallace, John Harper, Cyrielle Holuka, Jeffrey Steinberg, Jacquelyn Myers, David Cullins, Emilia Kooienga, Mark Engelken, Guillem Castro-Bono, Brittnie-lee Duffus, Marta Derecka, Esther Obeng
Journal: Blood
Blood (2025) 146 (Supplement 1): 861.
https://doi.org/10.1182/blood-2025-861
Published: 2025
Journal Articles

GPRASP2 maintains hematopoietic stem cell quiescence and self-renewal by receptor-mediated endocytosis

Free
Alanna Van Huizen, Mattieu Zhai, Zakiya Kelley, Emilia Kooienga, Preeti Dabas, Lance Palmer, Kate Tisdale, Dirk Loeffler, Dewmi Rathnayake, Madeleine Rodgers, Ishani Sharma, Antonio Morales-Hernandez, Shannon McKinney-Freeman
Journal: Blood
Blood (2025) 146 (Supplement 1): 1374.
https://doi.org/10.1182/blood-2025-1374
Published: 2025
Journal Articles

Single-cell analysis reveals distinct γ-globin expression profiles in sickle cell disease with pancellular fetal hemoglobin

Free
Phillip Doerfler, Yichao Li, Yu Yao, Ruopeng Feng, Thiyagaraj Mayuranathan, Jingjing Zhang, Emilia Kooienga, David Cullins, Rohith Jesudas, Dillon Williams, David Wood, Jane Hankins, Yong Cheng, Mitchell Weiss
Journal: Blood
Blood (2025) 146 (Supplement 1): 1149.
https://doi.org/10.1182/blood-2025-1149
Published: 2025
Journal Articles

Hematopoietic Stem Cells from Mice and Individuals with Sickle Cell Disease Display Premature Senescence and Loss of Function That Is Targetable By Senolytic Therapy

Free
Aditya Barve, Mahmoud Dabbah, Emilia Kooienga, Esther A. Obeng, Jacquelyn Myers, Akshay Sharma, Shannon McKinney-Freeman
Journal: Blood
Blood (2023) 142 (Supplement 1): 33.
https://doi.org/10.1182/blood-2023-190264
Published: 2023
Journal Articles

Sickle Cell Disease Compromises the Hematopoietic Stem Cells Bone Marrow Niche with Age

Free
Mahmoud Dabbah, Aditya Barve, Emilia Kooienga, Zakiya Kelley, Jason M Butler, Marta Derecka, Shannon McKinney-Freeman
Journal: Blood
Blood (2022) 140 (Supplement 1): 8622.
https://doi.org/10.1182/blood-2022-164738
Published: 2022