1-20 of 24
Sebastien Malinge
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Disruption of cotranscriptional splicing suggests that RBM39 is a therapeutic target in acute lymphoblastic leukemia

Qi Jin, Ethan Harris, Jacquelyn A Myers, Rashid Mehmood, Anitria Cotton, Hazheen K Shirnekhi, David W Baggett, Jeremy Qiang Wen, Andrew B Schild, Rahul S Bhansali, Jonathon Klein, Shilpa Narina, Tim Pieters, Akihide. Yoshimi, Shondra M Pruett-Miller, Richard Kriwacki, Omar Abdel-Wahab, Sebastien Malinge, Panagiotis Ntziachristos, Esther A Obeng, John D. Crispino
Journal: Blood
Blood blood.2024024281.
https://doi.org/10.1182/blood.2024024281
Published: 2024
Includes: Supplemental data
Journal Articles

Targeting Bone Marrow Microenvironment for Treatment of High-Risk B-Cell Acute Lymphoblastic Leukemia

Laurence C Cheung, Sarah Trinder, Anastasia Hughes, Benjamin Mullin, Sarah Rashid, Jinbo Yuan, Jiake Xu, Owen Duncan, Richard B. Lock, Sebastien Malinge, Vincent Kuek, Rishi Sury Kotecha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2709.
https://doi.org/10.1182/blood-2023-173503
Published: 2023
Journal Articles

It is more “unbalanced” than you think

Sébastien Malinge
Journal: Blood
Blood (2023) 141 (10): 1095–1096.
https://doi.org/10.1182/blood.2022019194
Published: 2023
Journal Articles

Modeling Acute Megakaryoblastic Leukemia of Down Syndrome Using Induced Pluripotent Stem Cells

Brahim Arkoun, Virginie Dufour, Aurélie Siret, Stefania Mazzi, Yasmine Mammasse, Mathieu Vieira, Fabien Boudia, Elie Robert, Zakia Aid, Marie Cambot, Rachel Petermann, Sylvie Souquere, Philippe Rameau, Cyril Catelain, Romain Diot, Gérard Tachdjian, Najet Debili, Isabelle Plo, Hana Raslova, Sebastien Malinge, Eric Soler, Thomas Mercher, William Vainchenker
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-140986
Published: 2020
Journal Articles

SNAIL trail in myeloid malignancies

Sébastien Malinge
Journal: Blood
Blood (2020) 136 (8): 920–921.
https://doi.org/10.1182/blood.2020006613
Published: 2020
Journal Articles

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Alexandre Fagnan, Frederik Otzen Bagger, Maria-Riera Piqué-Borràs, Cathy Ignacimouttou, Alexis Caulier, Cécile K. Lopez, Elie Robert, Benjamin Uzan, Véronique Gelsi-Boyer, Zakia Aid, Cécile Thirant, Ute Moll, Samantha Tauchmann, Amina Kurtovic-Kozaric, Jaroslaw Maciejewski, Christine Dierks, Orietta Spinelli, Silvia Salmoiraghi, Thomas Pabst, Kazuya Shimoda, Virginie Deleuze, Hélène Lapillonne, Connor Sweeney, Véronique De Mas, Betty Leite, Zahra Kadri, Sébastien Malinge, Stéphane de Botton, Jean-Baptiste Micol, Benjamin Kile, Catherine L. Carmichael, Ilaria Iacobucci, Charles G. Mullighan, Martin Carroll, Peter Valent, Olivier A. Bernard, Eric Delabesse, Paresh Vyas, Daniel Birnbaum, Eduardo Anguita, Loïc Garçon, Eric Soler, Juerg Schwaller, Thomas Mercher
Journal: Blood
Blood (2020) 136 (6): 698–714.
https://doi.org/10.1182/blood.2019003062
Published: 2020
Includes: Supplemental data
Journal Articles

STAT3 Is Activated By DYRK1A and Is a Potential Therapeutic Target in B-ALL

Malini Rammohan, MS, Rahul S. Bhansali, Yi-Chien Tsai, Alexander Dong, Sebastien Malinge, PhD, Jean-Pierre Bourquin, MD PhD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 3898.
https://doi.org/10.1182/blood-2018-99-115429
Published: 2018
Journal Articles

The Chromosome 21 Kinase DYRK1A and Its Substrate FOXO1 Constitute a Novel Therapeutic Pathway in B-ALL

Rahul S. Bhansali, Malini Rammohan, MS, Ji Heon Paul Lee, MD PhD, Sebastien Malinge, PhD, Yi-Chien Tsai, Nobuko Hijiya, MD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD, Corinne Fruit, Thierry Besson, PhD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 548.
https://doi.org/10.1182/blood-2018-99-119854
Published: 2018
Journal Articles

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis

Andrew Volk, PhD, Kaiwei Liang, PhD, Jianyun Zhao, Xinyu Li, Marinka Bulic, Stacy Marshall, Jeffrey W. Taub, MD, Yubin Ge, PhD, Sebastien Malinge, PhD, Elizabeth Bartom, PhD, Ali Shilatifard, PhD, John D. Crispino, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 245.
https://doi.org/10.1182/blood.V130.Suppl_1.245.245
Published: 2017
Journal Articles

DYRK1A Is a Therapeutic Target in B-ALL in Children with Down Syndrome

Paul Lee, MD PhD, Rahul Bhansali, BA, Malini Rammohan, BS, MS, Nobuko Hijiya, MD, Shai Izraeli, MD Prof, Jean-Pierre Bourquin, MD PhD, Sebastien Malinge, PhD, John Crispino, PhD MBA
Journal: Blood
Blood (2016) 128 (22): 2721.
https://doi.org/10.1182/blood.V128.22.2721.2721
Published: 2016
Journal Articles

ETO2-GLIS2 Controls Differentiation Arrest and Self-Renewal through Aberrant Enhancers Regulation in Pediatric Leukemia

Cecile Thirant, PhD, Cecile K Lopez, Cathy Ignacimouttou, M'Boyba Diop, Lou Le Mouël, MD, Clarisse Thiollier, MD PhD, Aurelie Siret, Philippe Dessen, Zakia Aid, Julie Riviere, PhD, Philippe Rameau, Celine Lefebvre, Mehdi Khaled, PhD, Guy Leverger, MD, Paola Fabiola Ballerini, MDPhD, Arnaud Petit, MD PhD, Hana Raslova, PhD, Catherine Carmichael, Benjamin T. Kile, PhD, Eric Soler, PhD, John Crispino, PhD, Christian Wichmann, MD, Camille Lobry, PhD, Francoise Pfumio, PhD, Juerg Schwaller, MD, Nathalie M. Droin, PhD, William Vainchenker, MD PhD, Olivier A. Bernard, PhD, Sebastien Malinge, PhD, Thomas Mercher, PhD
Journal: Blood
Blood (2016) 128 (22): 572.
https://doi.org/10.1182/blood.V128.22.572.572
Published: 2016
Journal Articles

Aurora A Kinase Is a Novel Therapeutic Target In The Myeloproliferative Neoplasms

Qiang Jeremy Wen, PhD, MD, Benjamin Goldenson, Sebastien Malinge, PhD, Brady L Stein, MD MHS, Terra L Lasho, MT, (ASCP), Lawrence Breyfogle, Rachael Schultz, Qiong Yang, Laure gilles-Gendre, Priya Koppikar, Omar Abdel-Wahab, MD, Benjamin L. Ebert, MD, PhD, Animesh Pardanani, MBBS, PhD, Sandeep Gurbuxani, MBBS, PhD, Ross L. Levine, MD, Ann Mullally, MD, Ayalew Tefferi, MD, John D Crispino, PhD
Journal: Blood
Blood (2013) 122 (21): 109.
https://doi.org/10.1182/blood.V122.21.109.109
Published: 2013
Journal Articles

The Chromosome 21 Kinase DYRK1A Controls Cell Cycle Exit and Survival During Lymphoid Development and Is a Novel Therapeutic Target In Acute Lymphoblastic Leukemia

Benjamin J. Thompson, MD, PhD, Lauren Diebold, Sebastien Malinge, PhD, Bertrand Leblond, Anne-Sophie Casagrande, Laurent Désiré, Alicia Foucourt, Thierry Besson, Nobuko Hijiya, MD, John D. Crispino, PhD
Journal: Blood
Blood (2013) 122 (21): 814.
https://doi.org/10.1182/blood.V122.21.814.814
Published: 2013
Journal Articles

Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes

e-blood
Sébastien Malinge, Tim Chlon, Louis C. Doré, Rhett P. Ketterling, Martin S. Tallman, Elisabeth Paietta, Alan S. Gamis, Jeffrey W. Taub, Stella T. Chou, Mitchell J. Weiss, John D. Crispino, Maria E. Figueroa
Journal: Blood
Blood (2013) 122 (14): e33–e43.
https://doi.org/10.1182/blood-2013-05-503011
Published: 2013
Includes: Supplemental data
Journal Articles

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

Sébastien Malinge, Clarisse Thiollier, Timothy M. Chlon, Louis C. Doré, Lauren Diebold, Olivier Bluteau, Vinciane Mabialah, William Vainchenker, Philippe Dessen, Susan Winandy, Thomas Mercher, John D. Crispino
Journal: Blood
Blood (2013) 121 (13): 2440–2451.
https://doi.org/10.1182/blood-2012-08-450627
Published: 2013
Includes: Supplemental data
Journal Articles

Induction of Megakaryocyte Polyploidization in Combination with JAK Inhibition As a Novel Therapeutic Strategy for Myeloproliferative Neoplasms

Qiang Jeremy Wen, MD, PhD, Benjamin Goldenson, Sebastien Malinge, PhD, Priya Koppikar, Ross L Levine, MD, Ayalew Tefferi, MD, John Crispino, PhD
Journal: Blood
Blood (2011) 118 (21): 64.
https://doi.org/10.1182/blood.V118.21.64.64
Published: 2011
Journal Articles

Development of Acute Megakaryoblastic Leukemia in Down Syndrome Is Associated with Sequential Epigenetic Changes That Target the Down Syndrome Critical Region on Chromosome 21,

Maria E Figueroa, MD, Sebastien Malinge, PhD, Timothy M Chlon, Yushan Li, Elisabeth Paietta, PhD, Hugo F. Fernandez, MD, Martin S. Tallman, MD, Mitchell J Weiss, MD, Stella T Chou, MD, Ari Melnick, MD, John Crispino, PhD
Journal: Blood
Blood (2011) 118 (21): 3451.
https://doi.org/10.1182/blood.V118.21.3451.3451
Published: 2011
Journal Articles

Notch: of mice and men?

Sebastien Malinge, John Crispino
Journal: Blood
Blood (2010) 116 (25): 5438–5439.
https://doi.org/10.1182/blood-2010-09-308395
Published: 2010
Journal Articles

Ikaros Is a GATA Switch Target Gene That Restrains Megakaryopoiesis In Part by Blocking Notch Signaling.

Sebastien Malinge, PhD, Clarisse Thiollier, Timothy M Chlon, Louis C Dore, Lauren Diebold, Susan Winandy, PhD, Thomas Mercher, PhD, John Crispino, PhD
Journal: Blood
Blood (2010) 116 (21): 1602.
https://doi.org/10.1182/blood.V116.21.1602.1602
Published: 2010
Journal Articles

Development of a Mouse Model of DS Megakaryoblastic Leukemia and Identification of the Hsa21 Gene DYRK1A as a Prominent Contributor to DS-AMKL

Sebastien Malinge, PhD, Gina Kirsammer, PhD, Meghan Bliss-Moreau, Timothy M Chlon, Lauren Diebold, Stella T Chou, MD, Mitchell Weiss, MD, Sandeep Gurbuxani, MBBS, PhD, John Crispino, PhD
Journal: Blood
Blood (2010) 116 (21): 469.
https://doi.org/10.1182/blood.V116.21.469.469
Published: 2010