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Timothy M. Chlon
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Journal Articles

Heterozygous Mutations in DDX41 Cause Erythroid Progenitor Cell Defects

Timothy M Chlon, Emily Stepanchick, Analise Sulentic, Kathleen Hueneman, Daniel Starczynowski
Journal: Blood
Blood (2021) 138 (Supplement 1): 148.
https://doi.org/10.1182/blood-2021-153544
Published: 2021
Journal Articles

The Inherited MDS Gene DDX41 Is Essential for Ribosomal RNA Processing through Regulation of Snorna Biogenesis

Timothy M Chlon, PhD, Emily Stepanchick, Daniel Starczynowski, PhD, Kathleen Hueneman
Journal: Blood
Blood (2020) 136 (Supplement 1): 40.
https://doi.org/10.1182/blood-2020-143222
Published: 2020
Journal Articles

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Timothy M Chlon, PhD, Emily Stepanchick, Kwangmin Choi, PhD, Yi Zheng, PhD, Kathleen Hueneman, Ashley Davis, Daniel T. Starczynowski, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 773.
https://doi.org/10.1182/blood-2019-127471
Published: 2019
Journal Articles

Chronic immune response dysregulation in MDS pathogenesis

Laura Barreyro, Timothy M. Chlon, Daniel T. Starczynowski
Journal: Blood
Blood (2018) 132 (15): 1553–1560.
https://doi.org/10.1182/blood-2018-03-784116
Published: 2018
Journal Articles

Inducible Loss of the Fanconi Anemia Pathway in iPSC Causes Rapid Cell Cycle Arrest and Apoptosis through ATM/ATR and p53 Signaling

Timothy M Chlon, PhD, Elizabeth E Hoskins, Sonya Ruiz-Torres, Christopher N Mayhew, PhD, Kathryn A Wikenheiser-Brokamp, MD PhD, Stella M. Davies, MBBS, PhD, Parinda A. Mehta, Kasiani C. Myers, MD, James M Wells, PhD, Susanne I Wells, PhD
Journal: Blood
Blood (2014) 124 (21): 3528.
https://doi.org/10.1182/blood.V124.21.3528.3528
Published: 2014
Journal Articles

Stage Selective Requirement For The N-Terminus Of GATA1 During Erythropoiesis

Monika J Stankiewicz, PhD, Timothy M Chlon, John D Crispino, PhD
Journal: Blood
Blood (2013) 122 (21): 3670.
https://doi.org/10.1182/blood.V122.21.3670.3670
Published: 2013
Journal Articles

Perturbation of fetal hematopoiesis in a mouse model of Down syndrome’s transient myeloproliferative disorder

Yehudit Birger, Liat Goldberg, Timothy M. Chlon, Benjamin Goldenson, Inna Muler, Ginette Schiby, Jasmin Jacob-Hirsch, Gideon Rechavi, John D. Crispino, Shai Izraeli
Journal: Blood
Blood (2013) 122 (6): 988–998.
https://doi.org/10.1182/blood-2012-10-460998
Published: 2013
Includes: Supplemental data
Journal Articles

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

Sébastien Malinge, Clarisse Thiollier, Timothy M. Chlon, Louis C. Doré, Lauren Diebold, Olivier Bluteau, Vinciane Mabialah, William Vainchenker, Philippe Dessen, Susan Winandy, Thomas Mercher, John D. Crispino
Journal: Blood
Blood (2013) 121 (13): 2440–2451.
https://doi.org/10.1182/blood-2012-08-450627
Published: 2013
Includes: Supplemental data
Journal Articles

Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis

Louis C. Doré, Timothy M. Chlon, Christopher D. Brown, Kevin P. White, John D. Crispino
Journal: Blood
Blood (2012) 119 (16): 3724–3733.
https://doi.org/10.1182/blood-2011-09-380634
Published: 2012
Includes: Supplemental data
Journal Articles

Development of Acute Megakaryoblastic Leukemia in Down Syndrome Is Associated with Sequential Epigenetic Changes That Target the Down Syndrome Critical Region on Chromosome 21,

Maria E Figueroa, MD, Sebastien Malinge, PhD, Timothy M Chlon, Yushan Li, Elisabeth Paietta, PhD, Hugo F. Fernandez, MD, Martin S. Tallman, MD, Mitchell J Weiss, MD, Stella T Chou, MD, Ari Melnick, MD, John Crispino, PhD
Journal: Blood
Blood (2011) 118 (21): 3451.
https://doi.org/10.1182/blood.V118.21.3451.3451
Published: 2011
Journal Articles

The Leukemic Isoform GATA-1s Is Deficient In Chromatin Occupancy: Implications for AMKL.

Timothy M Chlon, Louis C Dore, John Crispino, PhD
Journal: Blood
Blood (2010) 116 (21): 3643.
https://doi.org/10.1182/blood.V116.21.3643.3643
Published: 2010
Journal Articles

Ikaros Is a GATA Switch Target Gene That Restrains Megakaryopoiesis In Part by Blocking Notch Signaling.

Sebastien Malinge, PhD, Clarisse Thiollier, Timothy M Chlon, Louis C Dore, Lauren Diebold, Susan Winandy, PhD, Thomas Mercher, PhD, John Crispino, PhD
Journal: Blood
Blood (2010) 116 (21): 1602.
https://doi.org/10.1182/blood.V116.21.1602.1602
Published: 2010
Journal Articles

Development of a Mouse Model of DS Megakaryoblastic Leukemia and Identification of the Hsa21 Gene DYRK1A as a Prominent Contributor to DS-AMKL

Sebastien Malinge, PhD, Gina Kirsammer, PhD, Meghan Bliss-Moreau, Timothy M Chlon, Lauren Diebold, Stella T Chou, MD, Mitchell Weiss, MD, Sandeep Gurbuxani, MBBS, PhD, John Crispino, PhD
Journal: Blood
Blood (2010) 116 (21): 469.
https://doi.org/10.1182/blood.V116.21.469.469
Published: 2010
Journal Articles

Gabp Transcription Factor Is Required for the Development of Mouse Megakaryocytes.

Zhong-Fa Yang, PhD, Timothy M Chlon, John Crispino, PhD, Alan G. Rosmarin, MD
Journal: Blood
Blood (2010) 116 (21): 2604.
https://doi.org/10.1182/blood.V116.21.2604.2604
Published: 2010
Journal Articles

Identification of a GATA Switch In Megakaryocytic Development.

Louis C Dore, Timothy M Chlon, Zan Huang, PhD, John Crispino, PhD
Journal: Blood
Blood (2010) 116 (21): 2605.
https://doi.org/10.1182/blood.V116.21.2605.2605
Published: 2010
Journal Articles

Hypomorphic Alleles of PU.1 Result in Impaired Myelopoiesis and Target Gene Expression.

Isaac B. Houston, Meghana B. Kamath, Brock L. Schweitzer, Timothy M. Chlon, Jennifer K. Ondr, Ph.D., Rodney P. DeKoter, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 1180.
https://doi.org/10.1182/blood.V108.11.1180.1180
Published: 2006