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Yehudit Birger
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Journal Articles

Loss of function of ENT3 drives histiocytosis and inflammation through TLR-MAPK signaling

Ruth Shiloh, Ruth Lubin, Odeya David, Ifat Geron, Elimelech Okon, Idit Hazan, Marketa Zaliova, Gil Amarilyo, Yehudit Birger, Yael Borovitz, Dafna Brik, Arnon Broides, Sarit Cohen-Kedar, Liora Harel, Eyal Kristal, Daria Kozlova, Galina Ling, Mika Shapira Rootman, Noa Shefer Averbuch, Shiri Spielman, Jan Trka, Shai Izraeli, Simon Yona, Sarah Elitzur
Journal: Blood
Blood (2023) 142 (20): 1740–1751.
https://doi.org/10.1182/blood.2023020714
Published: 2023
Includes: Supplemental data
Journal Articles

Deep Proteomic Analysis Reveals Shared Terminal Mechanisms for Familial Hemophagocytic Lymphohistiocytosis and Lymphoma-Associated Hyperinflammation

Adi Zoref-Lorenz, Uri Abadi, Ronit Gurion, Alexander Osnis, Joanne Yacobovich, Yehudit Birger, Galit Berger Pinto, Pia Raanani, Arnon Nagler, Shai Dulberg, Asaf Madi, Gilad Itchaki, Martin H. Ellis, Shai Izraeli, Michael B. Jordan
Journal: Blood
Blood (2023) 142 (Supplement 1): 677.
https://doi.org/10.1182/blood-2023-189849
Published: 2023
Journal Articles

Deep Multi-Omic Analysis of Familial Hemophagocytic Lymphohistiocytosis Reveals Distinctive Immune Features of the Disease

Michael B Jordan, Adi Zoref-Lorenz, Pearce Charles Kieser, Galit Berger, Yehudit Birger, Shai Izraeli, Joanne Yacobovich
Journal: Blood
Blood (2022) 140 (Supplement 1): 2601–2602.
https://doi.org/10.1182/blood-2022-170799
Published: 2022
Journal Articles

ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells

Hila Fishman, Shreyas Madiwale, Ifat Geron, Vase Bari, Wouter Van Loocke, Yael Kirschenbaum, Itamar Ganmore, Eitan Kugler, Avigail Rein-Gil, Gilgi Friedlander, Ginette Schiby, Yehudit Birger, Sabine Strehl, Jean Soulier, Birgit Knoechel, Adolfo Ferrando, Sharon Noy-Lotan, Arnon Nagler, James C. Mulloy, Pieter Van Vlierberghe, Shai Izraeli
Journal: Blood
Blood (2022) 139 (3): 399–412.
https://doi.org/10.1182/blood.2020010405
Published: 2022
Includes: Supplemental data
Journal Articles

Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis

Te Ling, Yehudit Birger, Monika J. Stankiewicz, Nissim Ben-Haim, Tomer Kalisky, Avigail Rein, Eitan Kugler, Wei Chen, Chunling Fu, Kevin Zhang, Hiral Patel, Jacek W. Sikora, Young Ah Goo, Neil Kelleher, Lihua Zou, Shai Izraeli, John D. Crispino
Journal: Blood
Blood (2019) 134 (19): 1619–1631.
https://doi.org/10.1182/blood.2019001234
Published: 2019
Includes: Supplemental data
Journal Articles

Global Chromatin Occupancy and Epigenetic Signature Analysis Reveal New Insights into the Function of GATA1 N-Terminus in Erythropoiesis

Te Ling, PhD, Yehudit Birger, PhD, Monika Stankiewicz, PhD, Nissim Ben-Haim, Itamar Kanter, Tomer Kalisky, Avigail Rein Gil, MD, Neil L Kelleher, PhD, Lihua Zou, PhD, Shai Izraeli, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 533.
https://doi.org/10.1182/blood-2018-99-115338
Published: 2018
Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 566.
https://doi.org/10.1182/blood-2018-99-115913
Published: 2018
Journal Articles

MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome

Lital Shaham, Elena Vendramini, Yubin Ge, Yaron Goren, Yehudit Birger, Marloes R. Tijssen, Maureen McNulty, Ifat Geron, Omer Schwartzman, Liat Goldberg, Stella T. Chou, Holly Pitman, Mitchell J. Weiss, Shulamit Michaeli, Benjamin Sredni, Berthold Göttgens, John D. Crispino, Jeffrey W. Taub, Shai Izraeli
Journal: Blood
Blood (2015) 125 (8): 1292–1301.
https://doi.org/10.1182/blood-2014-06-581892
Published: 2015
Includes: Supplemental data
Journal Articles

Novel activating mutations lacking cysteine in type I cytokine receptors in acute lymphoblastic leukemia

Brief Report
Chen Shochat, Noa Tal, Vitalina Gryshkova, Yehudit Birger, Obul R. Bandapalli, Giovanni Cazzaniga, Nava Gershman, Andreas E. Kulozik, Andrea Biondi, Marc R. Mansour, Jean-Claude Twizere, Martina U. Muckenthaler, Nir Ben-Tal, Stefan N. Constantinescu, Dani Bercovich, Shai Izraeli
Journal: Blood
Blood (2014) 124 (1): 106–110.
https://doi.org/10.1182/blood-2013-10-529685
Published: 2014
Includes: Supplemental data
Journal Articles

Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia

Liat Goldberg, Marloes R. Tijssen, Yehudit Birger, Rebecca L. Hannah, Sarah J. Kinston, Judith Schütte, Dominik Beck, Kathy Knezevic, Ginette Schiby, Jasmine Jacob-Hirsch, Anat Biran, Yoel Kloog, Guido Marcucci, Clara D. Bloomfield, Peter D. Aplan, John E. Pimanda, Berthold Göttgens, Shai Izraeli
Journal: Blood
Blood (2013) 122 (15): 2694–2703.
https://doi.org/10.1182/blood-2013-01-477133
Published: 2013
Includes: Supplemental data
Journal Articles

Perturbation of fetal hematopoiesis in a mouse model of Down syndrome’s transient myeloproliferative disorder

Yehudit Birger, Liat Goldberg, Timothy M. Chlon, Benjamin Goldenson, Inna Muler, Ginette Schiby, Jasmin Jacob-Hirsch, Gideon Rechavi, John D. Crispino, Shai Izraeli
Journal: Blood
Blood (2013) 122 (6): 988–998.
https://doi.org/10.1182/blood-2012-10-460998
Published: 2013
Includes: Supplemental data
Journal Articles

ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer

Julie A. I. Thoms, Yehudit Birger, Sam Foster, Kathy Knezevic, Yael Kirschenbaum, Vashe Chandrakanthan, Georg Jonquieres, Dominik Spensberger, Jason W. Wong, S. Helen Oram, Sarah J. Kinston, Yoram Groner, Richard Lock, Karen L. MacKenzie, Berthold Göttgens, Shai Izraeli, John E. Pimanda
Journal: Blood
Blood (2011) 117 (26): 7079–7089.
https://doi.org/10.1182/blood-2010-12-317990
Published: 2011
Includes: Supplemental data
Journal Articles

MODELING and Targeting ERG -INDUCED Acute MYELOID LEUKEMIA (AML).

Gil Smooha, Yehudit Birger, PhD, Liat Goldberg, PhD, Jasmine Jacob-Hirsch, MSc, Ninette Amariglio, PhD, Gideon Rechavi, MD, PhD, Ditsa Levanon, PhD, Yoram Groner, PhD, Anat Taragan, Yoel Kloog, PhD, Jeremy Q Wen, PhD, MD, John Crispino, PhD, Michael D. Radmacher, Guido Marcucci, MD, Clara D. Bloomfield, MD, Shai Izraeli, MD
Journal: Blood
Blood (2009) 114 (22): 475.
https://doi.org/10.1182/blood.V114.22.475.475
Published: 2009