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Journal Articles

T-ALL and T-LBL: a notch apart

Rachael Pocock, Marc R. Mansour

Blood (2024) 144 (13): 1356–1357.

https://doi.org/10.1182/blood.2024026122

Published: 2024

Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Blood blood.2024024300.

https://doi.org/10.1182/blood.2024024300

Published: 2024

Includes: Supplemental data

Journal Articles

Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL

David O’Connor, Jose Espejo Valle-Inclán, Lucia Conde, Gianna Bloye, Sunniyat Rahman, Joana R. Costa, Jack Bartram, Stuart Adams, Gary Wright, Hillary Elrick, Kerry Wall, Sara Dyer, Christopher Howell, Galina Jigoulina, Javier Herrero, Isidro Cortes-Ciriano, Anthony V. Moorman, Marc R. Mansour

Blood (2024) 143 (10): 933–937.

https://doi.org/10.1182/blood.2023021906

Published: 2024

Includes: Supplemental data

Journal Articles

Identification, Monitoring and Reversibility of PARP Inhibitor Associated Clonal Haematopoiesis and Myelodysplastic Syndrome: A Case Series

Ellen Nuttall Musson, Michelle Lockley, Marc R. Mansour, Rowan E Miller, Jonathan Lederman, Elspeth Payne

Blood (2023) 142 (Supplement 1): 5607.

https://doi.org/10.1182/blood-2023-179828

Published: 2023

Journal Articles

Pharmacological Modulation of CD21 Antigen Density Enhances Chimeric Antigen Receptor (CAR-T) Cell Function

Nicola C Maciocia, Amy Burley, Malika Hoekx, Thaneswari Karpanasamy, Lydia Lee, David O'Connor, Marc R. Mansour, Asim Khwaja, Paul M Maciocia, Martin Pule

Blood (2022) 140 (Supplement 1): 4529–4530.

https://doi.org/10.1182/blood-2022-158973

Published: 2022

Journal Articles

The Clinico-Genomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

David O'Connor, Jonas Demeulemeester, Lucia Conde, Amy A. Kirkwood, Kent Fung, Foteini Papaleonidopoulou, Gianna Bloye, Nadine Farah, Sunniyat Rahman, Jeremy Hancock, Caroline Bateman, Sarah Inglott, Jon Mee, Javier Herrero, Peter Van Loo, Anthony V. Moorman, Ajay Vora, Marc R. Mansour

Blood (2022) 140 (Supplement 1): 1720–1721.

https://doi.org/10.1182/blood-2022-165308

Published: 2022

Journal Articles

The Hematopoietic Transcription Factor GATA3 Is the Main Activator of Enhancer-Mediated Activation of Oncogenic TAL1 in T-ALL

Joana R Costa, David O'Connor, Nurkaiyisah Anuar, Sunniyat Rahman, Nivedita Singh, Zhaodong China, Tanya Rapoz-D'Silva, Yang Li, Kent Fung, Sara Hyseni, Stephen Henderson, George Morrow, Yanping Guo, Javier Herrero, Richard Jenner, Dennis Keppei, A. Thomas Look, Marc R. Mansour

Blood (2022) 140 (Supplement 1): 3046–3047.

https://doi.org/10.1182/blood-2022-166396

Published: 2022

Journal Articles

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Blood (2022) 140 (Supplement 1): 1009–1010.

https://doi.org/10.1182/blood-2022-162930

Published: 2022

Journal Articles

Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia

Blood (2022) 140 (1): 25–37.

https://doi.org/10.1182/blood.2021013648

Published: 2022

Includes: Supplemental data

Journal Articles

First Analysis of the UKALL14 Randomized Trial to Determine Whether the Addition of Nelarabine to Standard Chemotherapy Improves Event Free Survival in Adults with T-Cell Acute Lymphoblastic Leukaemia (CRUK/09/006)

Clare J Rowntree, Amy A Kirkwood, Laura Clifton-Hadley, Nadine Farah, Marc R. Mansour, Jiaull Hussain, David I. Marks, Andrew K. McMillan, Tobias F. Menne, Anthony V. Moorman, Pip Patrick, Bela Wrench, Adele K. Fielding

Blood (2021) 138 (Supplement 1): 366.

https://doi.org/10.1182/blood-2021-152355

Published: 2021

Journal Articles

Anti-CCR9 CAR-T Cells for T Acute Lymphoblastic Leukemia

Paul M Maciocia, Patrycja Wawrzyniecka, Nicola C Maciocia, Amy Burley, David O'Connor, Theresa E. Leon, Tanya Rapoz-D'Silva, Thaneswari Karpanasamy, Martin Pule, Marc R. Mansour

Blood (2021) 138 (Supplement 1): 903.

https://doi.org/10.1182/blood-2021-146565

Published: 2021

Journal Articles

Metabolic Changes in Venetoclax Resistance Are Determined By Differentiation State in T-Cell Acute Lymphoblastic Leukemia

Alessandra Di Grande, Andrew Roe, Thomas Lefeivre, Theresa E. Leon, Marc R. Mansour, Jonathan Bond, Pieter Van Vlierberghe, Triona Ni Chonghaile

Blood (2021) 138 (Supplement 1): 3401.

https://doi.org/10.1182/blood-2021-152489

Published: 2021

Journal Articles

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-138501

Published: 2020

Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Blood (2020) 135 (19): 1685–1695.

https://doi.org/10.1182/blood.2019003880

Published: 2020

Includes: Supplemental data

Journal Articles

Utility of FDG-PET/CT in Lymphoblastic Lymphoma

Thomas A Fox, BSc, MSc, MRCP, Ben Carpenter, PhD, Asim Khwaja, Richard Halsey, MRCP, Victoria Grandage, Marc R. Mansour, MD PhD FRCPath, Adele K. Fielding, MBBS,PhDFRCP,FRCPath, Rachael E Hough, MD

Blood (2019) 134 (Supplement_1): 2890.

https://doi.org/10.1182/blood-2019-127379

Published: 2019

Journal Articles

Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress

Blood (2019) 134 (17): 1415–1429.

https://doi.org/10.1182/blood.2019001398

Published: 2019

Includes: Supplemental data

Journal Articles

Synthetic Lethal Screening Identifies CHK1 Inhibition As an Exploitable Vulnerability in EZH2 Deficient T-ALL

Theresa E. Leon, PhD MSc, BSc, Tanya Rapoz-D'Silva, BSc, MSc, Sunniyat Rahman, MBiochem, DIC, PhD, Michael Magnussen, BSc, MSc, Nadine Farah, MBBChir, MA, MRCP, FRCPath, Jose A. Guerra-Assunção, BSc, PhD, Rajeev Gupta, MB.ChB, PhD FRCP, FRCPath, Elisabeth P. Nacheva, MD PhD, Javier Herrero, PhD, David C. Linch, FRCP, Marc R. Mansour, MD PhD FRCPath

Blood (2017) 130 (Supplement 1): 1325.

https://doi.org/10.1182/blood.V130.Suppl_1.1325.1325

Published: 2017

Journal Articles

Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia

Blood (2017) 129 (24): 3221–3226.

https://doi.org/10.1182/blood-2016-09-742148

Published: 2017

Includes: Supplemental data

Journal Articles

Activation of the LMO2 Oncogene in T-ALL through a Somatically Acquired Neomorphic Promoter

Sunniyat Rahman, PhD DIC, MBiochem, Michael Magnussen, MSc, BSc, Theresa E. León, PhD MSc, BSc, Nadine Farah, FRCPath, MBBChir, MA, MRCP, Brian J. Abraham, PhD BSc, Zhaodong Li, PhD, Krisztina Z. Alapi, PhD MSc, BSc, Rachel J. Mitchell, MSc, Bsc, Tom Naughton, MSc, BSc, Adele K. Fielding, MB BS, PhD FRCP, FRCPath, Arnold Pizzey, Sophia Bustraan, BSc, Christopher Allen, BSc, Rosemary E. Gale, PhD BSc, David C. Linch, MD MRCP, MB BCh, BA, Richard A. Young, PhD BS, A. Thomas Look, MD, Marc R Mansour, MBChB, MRCP, PhD FRCPath

Blood (2016) 128 (22): 733.

https://doi.org/10.1182/blood.V128.22.733.733

Published: 2016

Journal Articles

Selective Inhibitor of Nuclear Export (SINE), Selinexor (KPT-330), Shows Remarkable Activity Against AML Leukemia-Initiating Cells

Julia Etchin, PhD, Bonnie Thi Le, M.S., Alex Kentsis, MD PhD, Marc R Mansour, MDPhD, Alla Berezovskaya, B.S., Richard M. Stone, MD, Ilene Galinsky, RNP, Daniel J. DeAngelo, MDPhD, Dilara McCauley, PhD, Michael Kauffman, MD PhD, Sharon Shacham, PhDMBA, Jean C.Y. Wang, MDPhD, Andrew L Kung, MD PhD, A. Thomas Look, MD

Blood (2014) 124 (21): 995.

https://doi.org/10.1182/blood.V124.21.995.995

Published: 2014

NARROW

T-ALL and T-LBL: a notch apart

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL

Identification, Monitoring and Reversibility of PARP Inhibitor Associated Clonal Haematopoiesis and Myelodysplastic Syndrome: A Case Series

Pharmacological Modulation of CD21 Antigen Density Enhances Chimeric Antigen Receptor (CAR-T) Cell Function

The Clinico-Genomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

The Hematopoietic Transcription Factor GATA3 Is the Main Activator of Enhancer-Mediated Activation of Oncogenic TAL1 in T-ALL

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia

First Analysis of the UKALL14 Randomized Trial to Determine Whether the Addition of Nelarabine to Standard Chemotherapy Improves Event Free Survival in Adults with T-Cell Acute Lymphoblastic Leukaemia (CRUK/09/006)

Anti-CCR9 CAR-T Cells for T Acute Lymphoblastic Leukemia

Metabolic Changes in Venetoclax Resistance Are Determined By Differentiation State in T-Cell Acute Lymphoblastic Leukemia

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Utility of FDG-PET/CT in Lymphoblastic Lymphoma

Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress

Synthetic Lethal Screening Identifies CHK1 Inhibition As an Exploitable Vulnerability in EZH2 Deficient T-ALL

Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia

Activation of the LMO2 Oncogene in T-ALL through a Somatically Acquired Neomorphic Promoter

Selective Inhibitor of Nuclear Export (SINE), Selinexor (KPT-330), Shows Remarkable Activity Against AML Leukemia-Initiating Cells

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American Society of Hematology

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American Society of Hematology

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