Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 21

Sort by

Sort Order Select

Journal Articles

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A - and NPM1 -altered leukemias

Blood (2024) 144 (11): 1206–1220.

https://doi.org/10.1182/blood.2023022480

Published: 2024

Includes: Supplemental data

Journal Articles

CD33-Deleted Hematopoietic Cells (Trem-Cel) Are Protected from CD33xCD3 Bispecific Antibody Treatment and Produce Significantly Reduced Levels of Inflammatory Cytokines in Preclinical Studies

Blood (2023) 142 (Supplement 1): 3425.

https://doi.org/10.1182/blood-2023-180216

Published: 2023

Journal Articles

UBE2N Regulates Oncoprotein Networks in Myeloid Malignancies

Chiharu Ishikawa, Laura Barreyro, Avery Sampson, Kathleen Hueneman, Kwangmin Choi, Lyndsey C. Bolanos, Andrew Volk, Stephanie S Watowich, Kenneth Greis, Daniel T. Starczynowski

Blood (2023) 142 (Supplement 1): 2762.

https://doi.org/10.1182/blood-2023-187438

Published: 2023

Journal Articles

UBE2N Is a Druggable Target and an Essential Ubiquitin-Conjugating Enzyme in Myeloid Malignancies

Chiharu Ishikawa, Laura Barreyro, Avery Sampson, Kathleen Hueneman, Kwangmin Choi, Lyndsey C Bolanos, Andrew Volk, Kenneth D Greis, Daniel T. Starczynowski

Blood (2022) 140 (Supplement 1): 5830.

https://doi.org/10.1182/blood-2022-167336

Published: 2022

Journal Articles

Cell-Intrinsic Inflammation Drives Progression from Myelodysplastic Syndromes to Leukemia

Laura Barreyro, PhD, Avery Sampson, BSc, Kathleen Hueneman, Kwangmin Choi, PhD, Susanne Christie, BSc, Dehua Wang, MD, Gang Huang, PhD, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 2983.

https://doi.org/10.1182/blood-2019-127307

Published: 2019

Journal Articles

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

Tomoya Muto, MD PhD, Maria Guillamot, PhD, Jing Fang, MD PhD, Luna Zea Redondo, MS, Kwangmin Choi, PhD, Yixiao Gong, MSc, Callum S Walker, MSc, Kathleen Hueneman, Lyndsey C Bolanos, BSc, Laura Barreyro, PhD, Lynn Lee, MD, Kenneth D Greis, PhD, Alireza Khodadadi-Jamayran, M.Sc., Amaia Lujambio, PhD, Scott W. Lowe, PhD, Iannis Aifantis, PhD, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 727.

https://doi.org/10.1182/blood-2019-121423

Published: 2019

Journal Articles

Therapeutic Targeting of the Ubiquitin Conjugating Enzyme UBE2N in Myeloid Malignancies

Blood (2018) 132 (Supplement 1): 4050.

https://doi.org/10.1182/blood-2018-99-115359

Published: 2018

Journal Articles

Chronic immune response dysregulation in MDS pathogenesis

Laura Barreyro, Timothy M. Chlon, Daniel T. Starczynowski

Blood (2018) 132 (15): 1553–1560.

https://doi.org/10.1182/blood-2018-03-784116

Published: 2018

Journal Articles

Inhibition of UBE2N As a Therapeutic Approach in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Laura Barreyro, PhD, Avery M Sampson, BS, Lyndsey Bolanos, BSc, Madeline Niederkorn, BS, Mario Pujato, PhD, Molly A Smith, BS, Muto Tomoya, MD PhD, Wendy D Haffey, PhD, Susanne Christie, Xiaona Liu, MD MS, Matthew Weirauch, PhD, Ken Greis, PhD, William L Seibel, PhD, Daniel T Starczynowski, PhD

Blood (2016) 128 (22): 579.

https://doi.org/10.1182/blood.V128.22.579.579

Published: 2016

Journal Articles

New Allosteric Inhibitors of Mutant IDH1 in Acute Myeloid Leukemia

Blood (2015) 126 (23): 787.

https://doi.org/10.1182/blood.V126.23.787.787

Published: 2015

Journal Articles

Minimal Reduction of PU.1 Is Sufficient to Induce a Preleukemic State and Promote Development of Acute Myeloid Leukemia

Britta Will, PhD, Thomas O. Vogler, Swathi-rao Narayanagari, Boris Bartholdy, Tihomira I. Todorova, MSc, Jiahao Chen, Yiting Yu, Jillian Mayer, Mariana da Silva Ferreira, Laura Barreyro, PhD, Luis Carvajal, Michael Roth, MD, Johanna van Oers, Sonja Schaetzlein, Christine McMahon, MD, Winifried Edelmann, Amit Verma, MD, Ulrich Steidl, MDPhD

Blood (2015) 126 (23): 305.

https://doi.org/10.1182/blood.V126.23.305.305

Published: 2015

Journal Articles

IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells

Carolina Schinke, Orsolya Giricz, Weijuan Li, Aditi Shastri, Shanisha Gordon, Laura Barreyro, Tushar Bhagat, Sanchari Bhattacharyya, Nandini Ramachandra, Matthias Bartenstein, Andrea Pellagatti, Jacqueline Boultwood, Amittha Wickrema, Yiting Yu, Britta Will, Sheng Wei, Ulrich Steidl, Amit Verma

Blood (2015) 125 (20): 3144–3152.

https://doi.org/10.1182/blood-2015-01-621631

Published: 2015

Includes: Supplemental data

Journal Articles

Targeting of MDS and AML Stem Cells Via Inhibition of STAT3 By Pyrimethamine

Aditi Shastri, MD, Carolina Schinke, MD, Asya Varshavsky Yanovsky, MD PhD, Tushar D. Bhagat, PhD, Orsolya Giricz, Laura Barreyro, M.Sc., Jacqueline Boultwood, PhD, Andrea Pellagati, Yiting Yu, PhD, Jennifer R. Brown, MD PhD, David A. Frank, MD PhD, Bhaskar Das, PhD, Suman Kambhampati, MD, Britta Will, PhD, Ulrich Steidl, MDPhD, Amit Verma, MD

Blood (2014) 124 (21): 3602.

https://doi.org/10.1182/blood.V124.21.3602.3602

Published: 2014

Journal Articles

Molecular and Functional Characterization Of The Novel Protein-Coding Gene Tihl (Translocated in Hodgkin’s Lymphoma) in Hematopoiesis

Ujunwa Cynthia Okoye-Okafor, M.Sc., Laura Barreyro, M.Sc., Heng Rui Wang, M.Sc., Boris Bartholdy, Ph.D., Britta Will, PhD, Tihomira I Todorova, B.A., Swathi-Rao Narayanagari, M.Sc., Mario Pujato, M.Sc., Masahiro Kawahara, MD, PhD, Bruce W. Woolcock, MSc, Randy D. Gascoyne, MD, Christian Steidl, MD, Ulrich Steidl, MD PhD

Blood (2013) 122 (21): 3680.

https://doi.org/10.1182/blood.V122.21.3680.3680

Published: 2013

Journal Articles

Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML

Alan H. Shih, MD PhD, Yanwen Jiang, PhD, Kaitlyn Shank, Suveg Pandey, Agnes Viale, PhD, Yongming Sun, PhD, Nicholas Socci, PhD, Alexander Robertson, PhD, Elisa de Stanchina, PhD, Todd Hricik, Franck Rapaport, PhD, Brittany Woods, Luisa Cimmino, PhD, Laura Barreyro, M.Sc., Ulrich Steidl, MD PhD, Iannis Aifantis, PhD, Ari Melnick, MD, Ross L. Levine, MD

Blood (2013) 122 (21): 476.

https://doi.org/10.1182/blood.V122.21.476.476

Published: 2013

Journal Articles

Inhibition Of CXCR2 As a Therapeutic Strategy In AML and MDS

Carolina Schinke, Orsolya Giricz, Shanisha A. K. Gordon, Laura Barreyro, M.Sc., Tushar D. Bhagat, Andrea Pellagatti, Jacqueline Boultwood, Yiting Yu, Ulrich Steidl, MD PhD, Amit Verma

Blood (2013) 122 (21): 484.

https://doi.org/10.1182/blood.V122.21.484.484

Published: 2013

Journal Articles

Parallel Transcriptional Analysis of Multiple Stem and Progenitor Populations Identifies Novel Commonly Dysregulated and Functionally Relevant Targets in AML

Blood (2012) 120 (21): 1875.

https://doi.org/10.1182/blood.V120.21.1875.1875

Published: 2012

Journal Articles

H2.0-Like Homeobox (HLX) Induces Unlimited Clonogenicity, Blocks Differentiation, and Cooperates with FLT3-ITD in the Induction of Acute Myeloid Leukemia

Ashley Pandolfi, M.Sc., Boris Bartholdy, Ph.D., Masahiro Kawahara, MD, Laura Barreyro, Britta Will, PhD, Robert Stanley, Roth Michael, MD, Ujunwa Cynthia Okoye-Okafor, M.Sc., Tihomira I Todorova, B.A., Maria E. Figueroa, MD, Ari Melnick, MD, Constantine S. Mitsiades, MD, PhD, Ulrich Steidl, MD, PhD

Blood (2012) 120 (21): 651.

https://doi.org/10.1182/blood.V120.21.651.651

Published: 2012

Journal Articles

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

Blood (2012) 120 (10): 2076–2086.

https://doi.org/10.1182/blood-2011-12-399683

Published: 2012

Includes: Supplemental data

Journal Articles

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS

Blood (2012) 120 (6): 1290–1298.

https://doi.org/10.1182/blood-2012-01-404699

Published: 2012

Includes: Supplemental data

NARROW

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A - and NPM1 -altered leukemias

CD33-Deleted Hematopoietic Cells (Trem-Cel) Are Protected from CD33xCD3 Bispecific Antibody Treatment and Produce Significantly Reduced Levels of Inflammatory Cytokines in Preclinical Studies

UBE2N Regulates Oncoprotein Networks in Myeloid Malignancies

UBE2N Is a Druggable Target and an Essential Ubiquitin-Conjugating Enzyme in Myeloid Malignancies

Cell-Intrinsic Inflammation Drives Progression from Myelodysplastic Syndromes to Leukemia

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

Therapeutic Targeting of the Ubiquitin Conjugating Enzyme UBE2N in Myeloid Malignancies

Chronic immune response dysregulation in MDS pathogenesis

Inhibition of UBE2N As a Therapeutic Approach in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

New Allosteric Inhibitors of Mutant IDH1 in Acute Myeloid Leukemia

Minimal Reduction of PU.1 Is Sufficient to Induce a Preleukemic State and Promote Development of Acute Myeloid Leukemia

IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells

Targeting of MDS and AML Stem Cells Via Inhibition of STAT3 By Pyrimethamine

Molecular and Functional Characterization Of The Novel Protein-Coding Gene Tihl (Translocated in Hodgkin’s Lymphoma) in Hematopoiesis

Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML

Inhibition Of CXCR2 As a Therapeutic Strategy In AML and MDS

Parallel Transcriptional Analysis of Multiple Stem and Progenitor Populations Identifies Novel Commonly Dysregulated and Functionally Relevant Targets in AML

H2.0-Like Homeobox (HLX) Induces Unlimited Clonogenicity, Blocks Differentiation, and Cooperates with FLT3-ITD in the Induction of Acute Myeloid Leukemia

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only