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Paul L. Shaffer
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Journal Articles

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A - and NPM1 -altered leukemias

Min Chul Kwon, Jan Willem Thuring, Olivier Querolle, Xuedong Dai, Tinne Verhulst, Vineet Pande, Ann Marien, Dries Goffin, Daniela V. Wenge, Hong Yue, Jevon A. Cutler, Cyrus Jin, Florian Perner, Shanna M. Hogeling, Paul L. Shaffer, Frank Jacobs, Petra Vinken, Wei Cai, Vikki Keersmaekers, Filmon Eyassu, Balpreet Bhogal, Karin Verstraeten, Sara El Ashkar, Jennifer A. Perry, Prathiba Jayaguru, Laura Barreyro, Anna Kuchnio, Nicolas Darville, Daniel Krosky, Gregor Urbanietz, Bie Verbist, James P. Edwards, Glenn S. Cowley, Robert Kirkpatrick, Ruth Steele, Lucille Ferrante, Christina Guttke, Nikki Daskalakis, E. Christine Pietsch, David M. Wilson, Ricardo Attar, Yusri Elsayed, Eric S. Fischer, Jan Jacob Schuringa, Scott A. Armstrong, Kathryn Packman, Ulrike Philippar
Journal: Blood
Blood (2024) 144 (11): 1206–1220.
https://doi.org/10.1182/blood.2023022480
Published: 2024
Includes: Supplemental data
Journal Articles

Discovery of a Novel, First-in-Class Bfl-1 BH3 Mimetic with Pro-Apoptotic Activity

Maarten Derks, Marian C. Bryan, Cindy Rockx, Tamara Schults, Tinne Verhulst, Beth Pietrak, Tatsuya Maehigashi, James C. Robertson, Andrew H. DeMaria, Kimberly Holt, Shaofei Ji, Victoria Wong, Ruud Bueters, Seong Joo Koo, Stefan Masure, Balpreet Bhogal, Christopher B. Kelly, Kaushik Mitra, Leopoldo Luistro, Paul L. Shaffer, Lawrence Szewczuk, Yusri Elsayed, Ulrike Philippar
Journal: Blood
Blood (2023) 142 (Supplement 1): 2824.
https://doi.org/10.1182/blood-2023-188516
Published: 2023