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Philippe Dessen
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Journal Articles

Dual role of EZH2 in megakaryocyte differentiation

Stefania Mazzi, Philippe Dessen, Mathieu Vieira, Virginie Dufour, Marie Cambot, Mira El Khoury, Iléana Antony-Debré, Brahim Arkoun, Francesca Basso-Valentina, Salwa BenAbdoulahab, Valerie Edmond, Philippe Rameau, Rachel Petermann, Monika Wittner, Bruno Cassinat, Isabelle Plo, Najet Debili, Hana Raslova, William Vainchenker
Journal: Blood
Blood (2021) 138 (17): 1603–1614.
https://doi.org/10.1182/blood.2019004638
Published: 2021
Includes: Supplemental data
Journal Articles

Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53

CME
Elise Chapiro, Elodie Pramil, M’boyba Diop, Damien Roos-Weil, Clémentine Dillard, Clémentine Gabillaud, Karim Maloum, Catherine Settegrana, Lucile Baseggio, Jean-François Lesesve, Mélanie Yon, Ludovic Jondreville, Claude Lesty, Frédéric Davi, Magali Le Garff-Tavernier, Nathalie Droin, Philippe Dessen, Caroline Algrin, Véronique Leblond, Jean Gabarre, Simon Bouzy, Virginie Eclache, Baptiste Gaillard, Evelyne Callet-Bauchu, Marc Muller, Christine Lefebvre, Nathalie Nadal, Antoine Ittel, Stéphanie Struski, Marie-Agnès Collonge-Rame, Benoit Quilichini, Sandra Fert-Ferrer, Nathalie Auger, Isabelle Radford-Weiss, Lena Wagner, Sebastian Scheinost, Thorsten Zenz, Santos A. Susin, Olivier A. Bernard, Florence Nguyen-Khac
Journal: Blood
Blood (2019) 134 (21): 1821–1831.
https://doi.org/10.1182/blood.2019001187
Published: 2019
Includes: Supplemental data
Journal Articles

Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum

Alain Sarasin, Samuel Quentin, Nathalie Droin, Mourad Sahbatou, Véronique Saada, Nathalie Auger, Yannick Boursin, Philippe Dessen, Anna Raimbault, Vahid Asnafi, Jean-Luc Schmutz, Alain Taïeb, Carlos F. M. Menck, Filippo Rosselli, Laurianne Drieu La Rochelle, Caroline Robert, Flore Sicre de Fontbrune, Marie Sébert, Thierry Leblanc, Patricia Kannouche, Stéphane De Botton, Eric Solary, Jean Soulier
Journal: Blood
Blood (2019) 133 (25): 2718–2724.
https://doi.org/10.1182/blood-2019-01-895698
Published: 2019
Includes: Supplemental data
Journal Articles

Genetic Characterization of B-Cell Prolymphocytic Leukemia (B-PLL): A Hierarchical Prognostic Model Involving MYC and TP53 Abnormalities. on Behalf of the Groupe Francophone De Cytogenetique Hematologique (GFCH) and the French Innovative Leukemia Organization (FILO) Group

Elise Chapiro, MD PhD, Damien Roos-Weil, MD, Nadia Bougacha, Clementine Gabillaud, Clémentine Dillard, Elodie Pramil, Melanie Yon, Karim Maloum, MD PhD, Catherine Settegrana, Lucile Baseggio, MD, Claude Lesty, Frederic Davi, MD PhD, Magali Le Garff-Tavernier, M'boyba Khadija Diop, Nathalie M Droin, PhD, Philippe Dessen, Veronique Leblond, Caroline Algrin, Simon Bouzy, Virginie Eclache, Baptiste Gaillard, Evelyne Callet-Bauchu, Marc Muller, MD, Christine Lefebvre, MD PhD, Nathalie Nadal, Antoine Ittel, PharmD, Stéphanie Struski, Marie-Agnes Collonge-Rame, Benoit Quilichini, Sandra Fert-Ferrer, Nathalie Auger, Isabelle Radford-Weiss, Lena Wagner, Sebastian Scheinost, Thorsten Zenz, MD, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 943.
https://doi.org/10.1182/blood-2018-99-115085
Published: 2018
Journal Articles

ETO2-GLIS2 Controls Differentiation Arrest and Self-Renewal through Aberrant Enhancers Regulation in Pediatric Leukemia

Cecile Thirant, PhD, Cecile K Lopez, Cathy Ignacimouttou, M'Boyba Diop, Lou Le Mouël, MD, Clarisse Thiollier, MD PhD, Aurelie Siret, Philippe Dessen, Zakia Aid, Julie Riviere, PhD, Philippe Rameau, Celine Lefebvre, Mehdi Khaled, PhD, Guy Leverger, MD, Paola Fabiola Ballerini, MDPhD, Arnaud Petit, MD PhD, Hana Raslova, PhD, Catherine Carmichael, Benjamin T. Kile, PhD, Eric Soler, PhD, John Crispino, PhD, Christian Wichmann, MD, Camille Lobry, PhD, Francoise Pfumio, PhD, Juerg Schwaller, MD, Nathalie M. Droin, PhD, William Vainchenker, MD PhD, Olivier A. Bernard, PhD, Sebastien Malinge, PhD, Thomas Mercher, PhD
Journal: Blood
Blood (2016) 128 (22): 572.
https://doi.org/10.1182/blood.V128.22.572.572
Published: 2016
Journal Articles

A Comprehensive Study of the VHL -R200W Chuvash Polycythemia Mutation Reveals a Gradual Dysregulation of the Hypoxia Pathway in Oncogenesis

Betty Gardie, PhD, Sophie Couvé, PhD, Charline Ladroue, PhD, Elodie Laine, PhD, Karène Mahtouk, PhD, Justine Guégan, M.Sc., Sophie Gad, PhD, Hélène Le Jeune, B.Sc., Bernard Lecomte, MD, Jean-Christophe Pagès, MD, PhD, Patrick Benusiglio, MD PhD, Brigitte Bressac-de Paillerets, Pharm.D., PhD, Jean Feunteun, PhD, Philippe Dessen, PhD, Sylvie Hermouet, MD, PhD, Luba Tchertanov, PhD, David R. Mole, PhD, William G. Kaelin, MD, Peter J Ratcliffe, PhD, Stephane Richard, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 4020.
https://doi.org/10.1182/blood.V124.21.4020.4020
Published: 2014
Journal Articles

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

Sébastien Malinge, Clarisse Thiollier, Timothy M. Chlon, Louis C. Doré, Lauren Diebold, Olivier Bluteau, Vinciane Mabialah, William Vainchenker, Philippe Dessen, Susan Winandy, Thomas Mercher, John D. Crispino
Journal: Blood
Blood (2013) 121 (13): 2440–2451.
https://doi.org/10.1182/blood-2012-08-450627
Published: 2013
Includes: Supplemental data
Journal Articles

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Laure Gilles, Dominique Bluteau, Siham Boukour, Yunhua Chang, Yanyan Zhang, Thomas Robert, Philippe Dessen, Najet Debili, Olivier A. Bernard, William Vainchenker, Hana Raslova
Journal: Blood
Blood (2009) 114 (19): 4221–4232.
https://doi.org/10.1182/blood-2009-03-209932
Published: 2009
Includes: Supplemental data
Journal Articles

TET2 Is a Novel Tumor Suppressor Gene Inactivated in Myeloproliferative Neoplasms: Identification of a Pre-JAK2 V617F Event

Francois Delhommeau, Sabrina Dupont, Chloe James, MD, PhD, Aline Masse, Jean Pierre le Couedic, Veronique Della Valle, Antonio Alberdi, Philippe Dessen, Michaela Fontenay, Nicole Casadevall, MD, Jean Soulier, MD, PhD, Olivier Bernard, William Vainchenker
Journal: Blood
Blood (2008) 112 (11): lba-3.
https://doi.org/10.1182/blood.V112.11.lba-3.lba-3
Published: 2008
Journal Articles

FLT3 Mediated MAPK Activation Participates in the Control of Megakaryopoiesis in Primary Myelofibrosis

Christophe Desterke, Hans Hasselbalch, MD, PHD, Dominique Bordessoule, MD, PhD, Heinz Gisslinger, MD, PhD, Alessandro Vannucchi, MD, PhD, Olivier Pierre-Louis, Carole Tonetti, Philippe Dessen, PhD, Vladimir Lazar, MD, PhD, Bernadette Guerton, Denis Clay, William Vainchenker, MD, PhD, Stephane Giraudier, MD, PhD, Marie-Caroline Le Bousse-Kerdiles, PhD
Journal: Blood
Blood (2007) 110 (11): 1532.
https://doi.org/10.1182/blood.V110.11.1532.1532
Published: 2007
Journal Articles

Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach

Hana Raslova, Audrey Kauffmann, Dalila Sekkaï, Hugues Ripoche, Fréderic Larbret, Thomas Robert, Diana Tronik Le Roux, Guido Kroemer, Najet Debili, Philippe Dessen, Vladimir Lazar, William Vainchenker
Journal: Blood
Blood (2006) 109 (8): 3225–3234.
https://doi.org/10.1182/blood-2006-07-037838
Published: 2006
Includes: Supplemental data
Journal Articles

The THAP–zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes

Corinne Cayrol, Chrystelle Lacroix, Catherine Mathe, Vincent Ecochard, Michele Ceribelli, Emilie Loreau, Vladimir Lazar, Philippe Dessen, Roberto Mantovani, Luc Aguilar, Jean-Philippe Girard
Journal: Blood
Blood (2006) 109 (2): 584–594.
https://doi.org/10.1182/blood-2006-03-012013
Published: 2006
Includes: Supplemental data
Journal Articles

Microarray Functional Comparison of CD34 + and Megakaryocytic Cell Transcriptomes in Myeloid Metaplasia with Myelofibrosis.

Marie-Caroline Le Bousse-Kerdiles, PhD, Christophe Desterke, Carole Tonetti, Philippe Dessen, PhD, Hugues Ripoche, Vladimir Lazar, PhD, MD, Bernadette Guerton, Denis Clay, William Vainchenker, PhD, MD, Stephane Giraudier, PhD, MD, Members of the French Inserm GEM European EUMNET Networks
Journal: Blood
Blood (2005) 106 (11): 3505.
https://doi.org/10.1182/blood.V106.11.3505.3505
Published: 2005