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Journal Articles

Infusion of Umbilical Cord Blood-Derived Natural Killer Cells in Immune-Deficient Mice for the Treatment of Resistant Acute Myeloid Leukaemia

Nadine Khalifé-Saleh, MD, Meriem Hasmim, MD PhD, Yanyan Zhang, PhD, Khalil Saleh, MD, Jean-Henri Bourhis, MD PhD, Fawzia Louache, PhD, Salem Chouaib, PhD

Blood (2016) 128 (22): 5727.

https://doi.org/10.1182/blood.V128.22.5727.5727

Published: 2016

Journal Articles

Targeting Acute Myeloid Leukemia with a New CXCR4 Antagonist IgG1 Antibody (PF-06747143)in NOD/SCID Mice

Yanyan Zhang, PhD, Erika Saavedra, MD, Ruoping Tang, Shu-Hui Liu, Tod Smeal, Valeria Fantin, PhD, Stephane De Botton, MD PhD, Ollivier Legrand, MD PhD, William Vainchenker, MD PhD, Flavia Pernasetti, Fawzia Louache, PhD

Blood (2015) 126 (23): 1362.

https://doi.org/10.1182/blood.V126.23.1362.1362

Published: 2015

Journal Articles

Activation of Oxidative Stress and Down-Regulation of Nuclear Factor Erythroid 2-Related Factor May Be Responsible for Disulfiram/Copper Complex Induced Apoptosis in Lymphoid Malignancy Cell Lines

Feili Chen, M.D., Jie Zha, M.D., Yanyan Zhang, M.D., Pengcheng Shi, M.D., Xutao Guo, M.D., Shiyun Wang, M.D., Weiguang Wang, M.D. PhD, Bing Xu, M.D. PhD

Blood (2012) 120 (21): 4869.

https://doi.org/10.1182/blood.V120.21.4869.4869

Published: 2012

Journal Articles

CXCR4 Inhibitors Selectively Eliminate CXCR4 Expressing Human Acute Myeloid Leukemia Cells in NOG Mouse Model

Yanyan Zhang, PhD, Satyananda Patel, Monika Wittner, Stephane De Botton, Eric Solary, William Vainchenker, MD, PhD, Paul Coppo, Fawzia Louache, PhD

Blood (2012) 120 (21): 1881.

https://doi.org/10.1182/blood.V120.21.1881.1881

Published: 2012

Journal Articles

Disulfiram, an Clinically Used Anti-Alcoholism Drug Has the Potential to Target Leukemia Stem and Progenitor Cells in a Copper-Dependent Manner

Bing Xu, M.D. PhD, Shiyun Wang, M.D., Feili Chen, M.D., Pengcheng Shi, M.D., Jie Zha, M.D., Yanyan Zhang, M.D., Xutao Guo, M.D., Weiguang Wang, M.D. PhD

Blood (2012) 120 (21): 4088.

https://doi.org/10.1182/blood.V120.21.4088.4088

Published: 2012

Journal Articles

CXCR4 Invalidation Limits the MLL-ENL Induced Leucemogenesis in Vivo

Yanyan Zhang, Hadjer Abdelouahab, Aline Betems, Monika Wittner, William Vainchenker, MD, PhD, Fawzia Louache, PhD

Blood (2012) 120 (21): 4089.

https://doi.org/10.1182/blood.V120.21.4089.4089

Published: 2012

Journal Articles

Myeloid-Derived Suppressive Cells Belonging to the Leukemic Clone Account for Immunosuppression In CMML

Nathalie Droin, Raphael Itzykson, Philippe Rameau, Margot Morabito, Thorsten Braun, Fawzia Louache, Yanyan Zhang, Stephane De Botton, Catherine Cordonnier, Bruno Quesnel, Pierre Fenaux, MD, PhD, William Vainchenker, Eric Solary

Blood (2010) 116 (21): 3997.

https://doi.org/10.1182/blood.V116.21.3997.3997

Published: 2010

Journal Articles

Stromal Microenvironment Regulates Progenitor Survival through Nitric Oxide Production.

Dima Jouni, Yanyan Zhang, Hakim Bouamar, Monika Wittner, William Vainchenker, MD, PhD, Fawzia Louache

Blood (2009) 114 (22): 1440.

https://doi.org/10.1182/blood.V114.22.1440.1440

Published: 2009

Journal Articles

CXCR7 Expression Restricts CXCR4/SDF-1 Mediated Hematopoietic-Supporting Activity of Stromal Cells by Decreasing Extracellular SDF-1 Availability.

Hakim Bouamar, Yanyan Zhang, Dima Jouni, Monika Wittner, Morad Bensidhoum, Peggy Jarrier, Hervé Petite, William Vainchenker, MD, PhD, Olivier Albagli, Fawzia Louache

Blood (2009) 114 (22): 1452.

https://doi.org/10.1182/blood.V114.22.1452.1452

Published: 2009

Journal Articles

CXCR4 Blockade as a New Targeted Therapy for Acute Myeloide Leukemia Characterised by High Cell Surface Density of CXCR4.

Yanyan Zhang, Dima Jouni, Monika Wittner, Hakim Bouamar, Herve Dombret, MD, PhD, FRCP, Paul Coppo, Paule Opolon, Nobutaka Fujii, Mamoru Ito, William Vainchenker, MD, PhD, Stephane de Botton, Fawzia Louache

Blood (2009) 114 (22): 4570.

https://doi.org/10.1182/blood.V114.22.4570.4570

Published: 2009

Journal Articles

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Laure Gilles, Dominique Bluteau, Siham Boukour, Yunhua Chang, Yanyan Zhang, Thomas Robert, Philippe Dessen, Najet Debili, Olivier A. Bernard, William Vainchenker, Hana Raslova

Blood (2009) 114 (19): 4221–4232.

https://doi.org/10.1182/blood-2009-03-209932

Published: 2009

Includes: Supplemental data

Journal Articles

Proplatelet formation is regulated by the Rho/ROCK pathway

Yunhua Chang, Frédéric Auradé, Frédéric Larbret, Yanyan Zhang, Jean-Pierre Le Couedic, Laurence Momeux, Jerôme Larghero, Jacques Bertoglio, Fawzia Louache, Elisabeth Cramer, William Vainchenker, Najet Debili

Blood (2007) 109 (10): 4229–4236.

https://doi.org/10.1182/blood-2006-04-020024

Published: 2007

Journal Articles

Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4 –/– chimeric mice

Adlen Foudi, Peggy Jarrier, Yanyan Zhang, Monika Wittner, Jean-Francois Geay, Yann Lecluse, Takashi Nagasawa, William Vainchenker, Fawzia Louache

Blood (2006) 107 (6): 2243–2251.

https://doi.org/10.1182/blood-2005-02-0581

Published: 2006

Journal Articles

RGS16 is a negative regulator of SDF-1–CXCR4 signaling in megakaryocytes

Magali Berthebaud, Christel Rivière, Peggy Jarrier, Adlen Foudi, Yanyan Zhang, Daniel Compagno, Anne Galy, William Vainchenker, Fawzia Louache

Blood (2005) 106 (9): 2962–2968.

https://doi.org/10.1182/blood-2005-02-0526

Published: 2005

Journal Articles

The Hematopoietic Reconstitution Defect of Mice Lacking CXCR4 Is Related to an Altered Retention of Hematopoietic Cells in the Bone Marrow.

Adlen Foudi, Yanyan Zhang, Jean-Francois Geay, Magali Berthebaud, Dorothee Buet, Peggy Jarrier, Takashi Nagasawa, William Vainchenker, Fawzia Louache

Blood (2004) 104 (11): 120.

https://doi.org/10.1182/blood.V104.11.120.120

Published: 2004

Journal Articles

Implication of HIF-1α but Not HIF-2α in the Hypoxic Response of Human Hematopoietic Progenitors.

Yanyan Zhang, Adlen Foudi, Magali Berthebaud, Dorothee Buet, Peggy Jarrier, William Vainchenker, Fawzia Louache

Blood (2004) 104 (11): 4154.

https://doi.org/10.1182/blood.V104.11.4154.4154

Published: 2004

NARROW

Infusion of Umbilical Cord Blood-Derived Natural Killer Cells in Immune-Deficient Mice for the Treatment of Resistant Acute Myeloid Leukaemia

Targeting Acute Myeloid Leukemia with a New CXCR4 Antagonist IgG1 Antibody (PF-06747143)in NOD/SCID Mice

Activation of Oxidative Stress and Down-Regulation of Nuclear Factor Erythroid 2-Related Factor May Be Responsible for Disulfiram/Copper Complex Induced Apoptosis in Lymphoid Malignancy Cell Lines

CXCR4 Inhibitors Selectively Eliminate CXCR4 Expressing Human Acute Myeloid Leukemia Cells in NOG Mouse Model

Disulfiram, an Clinically Used Anti-Alcoholism Drug Has the Potential to Target Leukemia Stem and Progenitor Cells in a Copper-Dependent Manner

CXCR4 Invalidation Limits the MLL-ENL Induced Leucemogenesis in Vivo

Myeloid-Derived Suppressive Cells Belonging to the Leukemic Clone Account for Immunosuppression In CMML

Stromal Microenvironment Regulates Progenitor Survival through Nitric Oxide Production.

CXCR7 Expression Restricts CXCR4/SDF-1 Mediated Hematopoietic-Supporting Activity of Stromal Cells by Decreasing Extracellular SDF-1 Availability.

CXCR4 Blockade as a New Targeted Therapy for Acute Myeloide Leukemia Characterised by High Cell Surface Density of CXCR4.

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Proplatelet formation is regulated by the Rho/ROCK pathway

Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4 –/– chimeric mice

RGS16 is a negative regulator of SDF-1–CXCR4 signaling in megakaryocytes

The Hematopoietic Reconstitution Defect of Mice Lacking CXCR4 Is Related to an Altered Retention of Hematopoietic Cells in the Bone Marrow.

Implication of HIF-1α but Not HIF-2α in the Hypoxic Response of Human Hematopoietic Progenitors.

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American Society of Hematology

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American Society of Hematology

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