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Clive D'Santos
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Journal Articles

UBTF tandem duplications generate a nuclear export signal motif that drives an XPO1 dependency in leukemia

Free
Juan Barajas, Aaron Phillips, Jina Wang, Melvin Thomas, Lisett Contreras, Masayuki Umeda, Ryan Hiltenbrand, Guangchun Song, Mike Walsh, Lauren Ezzell, Elizabeth Caldwell, Kelly Churion, Tamara Westover, Emily Xiong, Chandra Rolle, Jamila Moore, Josi Lott, Sandi Radko-Juettner, Amit Kumar, Wenjie Qi, Beisi Xu, Evangelia Papachristou, Clive D'Santos, Jing Ma, Burgess Freeman, Laura Janke, Richard Kriwacki, Jeffery Klco
Journal: Blood
Blood (2025) 146 (Supplement 1): 986.
https://doi.org/10.1182/blood-2025-986
Published: 2025
Journal Articles

Posttranscriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1 -mutant AML

Free
Aristi Damaskou, Rachael Wilson, Malgorzata Gozdecka, George Giotopoulos, Ryan Asby, Maria Eleftheriou, Muxin Gu, Christian Récher, Véronique Mansat-De Mas, Francois Vergez, Ambrine Sahal, Binje Vick, Evangelia K. Papachristou, Ashley Sawle, Eliza Yankova, Monika Dudek, Xiaoxuan Liu, James Russell, Justyna Rak, Christine Hilcenko, Clive D’Santos, Irmela Jeremias, Jean-Emmanuel Sarry, Konstantinos Tzelepis, Brian J. P. Huntly, Alan J. Warren, Omid Tavana, George S. Vassiliou
Journal: Blood
Blood (2025) 146 (10): 1239–1252.
https://doi.org/10.1182/blood.2024026113
Published: 2025
Includes: Supplemental data
Journal Articles

ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia

Free
Jingyu Chen, Vijitha Sathiaseelan, Andrew Moore, Shengjiang Tan, Chandra Sekkar Reddy Chilamakuri, Valar Nila Roamio Franklin, Arash Shahsavari, Constanze A. Jakwerth, Sandra B. Hake, Alan J. Warren, Irina Mohorianu, Clive D’Santos, Ingo Ringshausen
Journal: Blood
Blood (2021) 137 (26): 3629–3640.
https://doi.org/10.1182/blood.2020009960
Published: 2021
Includes: Supplemental data