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Journal Articles

ZAP-70 Integrates Tonic B Cell Receptor and Chemokine Signaling in IGHV unmutated Chronic Lymphocytic Leukemia

Chen Jingyu, Vijitha Sathiaseelan, Chandra Chilamakuri, Constanze Jakwerth, Clive S D'Santos, Ingo Ringshausen

Blood (2023) 142 (Supplement 1): 1896.

https://doi.org/10.1182/blood-2023-187344

Published: 2023

Journal Articles

CRISPR-Cas9 Genome Editing of Primary Chronic Lymphocytic Leukemia Cells

Judith Mateos-Jaimez, Maurizio Mangolini, Anna Vidal, Dolors Colomer, Elías Campo, Ingo Ringshausen, José I. Martín-Subero, Alba Maiques-Diaz

Blood (2022) 140 (Supplement 1): 9849–9850.

https://doi.org/10.1182/blood-2022-163443

Published: 2022

Journal Articles

Negative Feedback Regulation of MAPK Signaling Is an Important Driver of CLL Progression

Lisa Brandmeier, Veronika Ecker, Martina Stumpf, Piero Giansanti, Aida Varela Moreira, Lisa Pfeuffer, Marcel Fens, Junyan Lu, Bernhard Küster, Thomas Engleitner, Simon Heidegger, Ingo Ringshausen, Thorsten Zenz, Clemens-Martin Wendtner, Markus Müschen, Jürgen Ruland, Maike Buchner

Blood (2022) 140 (Supplement 1): 9840–9841.

https://doi.org/10.1182/blood-2022-160103

Published: 2022

Journal Articles

ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia

Jingyu Chen, Vijitha Sathiaseelan, Andrew Moore, Shengjiang Tan, Chandra Sekkar Reddy Chilamakuri, Valar Nila Roamio Franklin, Arash Shahsavari, Constanze A. Jakwerth, Sandra B. Hake, Alan J. Warren, Irina Mohorianu, Clive D’Santos, Ingo Ringshausen

Blood (2021) 137 (26): 3629–3640.

https://doi.org/10.1182/blood.2020009960

Published: 2021

Includes: Supplemental data

Journal Articles

IL-9 in CLL: sensing home and settling down!

Ingo Ringshausen

Blood (2021) 137 (16): 2130–2131.

https://doi.org/10.1182/blood.2020009464

Published: 2021

Journal Articles

Overcoming Multidrug Resistance in B Cell Malignancies By Antagonism of Stromal Mediated TGF-β Signalling

Eugene Park, PhD, Jingyu Chen, PhD, Andrew Moore, PhD, Michael Leitges, Seth E. Frietze, PhD, Ingo Ringshausen, MD

Blood (2020) 136 (Supplement 1): 17.

https://doi.org/10.1182/blood-2020-141952

Published: 2020

Journal Articles

Integration of innate into adaptive immune responses in ZAP-70–positive chronic lymphocytic leukemia

Michaela Wagner, Madlen Oelsner, Andrew Moore, Frederik Götte, Peer-Hendrik Kuhn, Torsten Haferlach, Michael Fiegl, Christian Bogner, E. Joanna Baxter, Christian Peschel, George A. Follows, Ingo Ringshausen

Blood (2016) 127 (4): 436–448.

https://doi.org/10.1182/blood-2015-05-646935

Published: 2016

Includes: Supplemental data

Journal Articles

ZAP70 Integrates BCR-Signaling into Innate Signaling Pathways in CLL

Michaela Wagner, Madlen Oelsner, Peer-Hendrik Kuhn, MD, Torsten Haferlach, MD, Michael Fiegl, MD, Christian Bogner, MD, Christian Peschel, MD, Ingo Ringshausen, MD

Blood (2014) 124 (21): 1944.

https://doi.org/10.1182/blood.V124.21.1944.1944

Published: 2014

Journal Articles

Proteinkinase C-β Inhibitors Mitigate Microenvironment-Mediated Survival Of CLL Cells and Sensitise Malignant B Cells To Cytotoxic Drugs

Gloria Lutzny, Zhoulei Li, Madlen Oelsner, Jolanta Slawska, Thomas Kocher, MSc, Alexander Egle, Christian Peschel, Ulrich Keller, Ingo Ringshausen, M.D.

Blood (2013) 122 (21): 669.

https://doi.org/10.1182/blood.V122.21.669.669

Published: 2013

Journal Articles

Protein Kinase C-β Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B-Cells in Vivo

Gloria Lutzny, Thomas Kocher, MSc, Martina Rudelius, Marc Schmidt-Supprian, Ludger Klein-Hitpass, Jan Dürig, Robert A.J. Oostendorp, PhD, Christian Peschel, MD, Alexander Egle, Ingo Ringshausen

Blood (2012) 120 (21): 314.

https://doi.org/10.1182/blood.V120.21.314.314

Published: 2012

Journal Articles

Bryostatin Enhances the Cytotoxic Effects of Anti-CD22 Immunotoxins in CLL by Two Distinct Mechanisms: Implications for a Sequential Therapy.

Ingo Ringshausen, Thomas Decker, Viola Biberacher, Christian Meyer zum Buschenfelde, Madlen Oelsner, Michaela Wagner, Christian Bogner, Christian Peschel, MD

Blood (2009) 114 (22): 3429.

https://doi.org/10.1182/blood.V114.22.3429.3429

Published: 2009

Journal Articles

Antifungal Therapy with Itraconazole Impairs Rituximab′s Anti-Lymphoma Effect by Inhibiting CD20 Recruitment to Lipid Rafts.

Christian Meyer zum Bueschenfelde, Yvonne Feuerstacke, Philipp Krainz, Ken Herrmann, Andreas Buck, Christian Peschel, MD, Ingo Ringshausen

Blood (2009) 114 (22): 2735.

https://doi.org/10.1182/blood.V114.22.2735.2735

Published: 2009

Journal Articles

Recruitment of PKC-Beta to Lipid Rafts Mediates Apoptosis-Resistance in Chronic Lymphocytic Leukemia Expressing Zap-70.

Ingo Ringshausen, Michaela Wagner, Gloria Lutzny, Madlen Oelsner, Yvonne Feuerstacke, Thomas Decker, Christian Bogner, Christian Peschel, MD, Christian Meyer zum Buschenfelde

Blood (2009) 114 (22): 2354.

https://doi.org/10.1182/blood.V114.22.2354.2354

Published: 2009

Journal Articles

Unraveling STAT Signaling in NPM/ALK-Induced Lymphoma: STAT3 but Not STAT5 Is Required for Lymphomagenesis in a Bone Marrow Transplantation Model Using Conditional Knockout Mice.

Tobias Dechow, Elisa Amon, Cornelius Miething, Rebekka Grundler, Nicole Schatz, Marcus Kremer, Wolfgang Reindl, Ingo Ringshausen, Christian Peschel, Justus Duyster

Blood (2009) 114 (22): 1969.

https://doi.org/10.1182/blood.V114.22.1969.1969

Published: 2009

Journal Articles

Inhibition of Protein Kinase C (PKC) delta with Rottlerin Induces Apoptosis in B-CLL Cells, Augments Chemotherapeutic Cytotoxicity and Inhibits Antiapoptotic Survival Signals.

Ingo Ringshausen, MD, Kathrin Weick, Madlene Oelsner, Christian Peschel, MD, Thomas Decker, MD

Blood (2004) 104 (11): 2800.

https://doi.org/10.1182/blood.V104.11.2800.2800

Published: 2004

Journal Articles

Rapamycin-induced G 1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin

Thomas Decker, Susanne Hipp, Ingo Ringshausen, Christian Bogner, Madlene Oelsner, Folker Schneller, Christian Peschel

Blood (2003) 101 (1): 278–285.

https://doi.org/10.1182/blood-2002-01-0189

Published: 2003

Journal Articles

Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cδ

Ingo Ringshausen, Folker Schneller, Christian Bogner, Susanne Hipp, Justus Duyster, Christian Peschel, Thomas Decker

Blood (2002) 100 (10): 3741–3748.

https://doi.org/10.1182/blood-2002-02-0539

Published: 2002

NARROW

ZAP-70 Integrates Tonic B Cell Receptor and Chemokine Signaling in IGHV unmutated Chronic Lymphocytic Leukemia

CRISPR-Cas9 Genome Editing of Primary Chronic Lymphocytic Leukemia Cells

Negative Feedback Regulation of MAPK Signaling Is an Important Driver of CLL Progression

ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia

IL-9 in CLL: sensing home and settling down!

Overcoming Multidrug Resistance in B Cell Malignancies By Antagonism of Stromal Mediated TGF-β Signalling

Integration of innate into adaptive immune responses in ZAP-70–positive chronic lymphocytic leukemia

ZAP70 Integrates BCR-Signaling into Innate Signaling Pathways in CLL

Proteinkinase C-β Inhibitors Mitigate Microenvironment-Mediated Survival Of CLL Cells and Sensitise Malignant B Cells To Cytotoxic Drugs

Protein Kinase C-β Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B-Cells in Vivo

Bryostatin Enhances the Cytotoxic Effects of Anti-CD22 Immunotoxins in CLL by Two Distinct Mechanisms: Implications for a Sequential Therapy.

Antifungal Therapy with Itraconazole Impairs Rituximab′s Anti-Lymphoma Effect by Inhibiting CD20 Recruitment to Lipid Rafts.

Recruitment of PKC-Beta to Lipid Rafts Mediates Apoptosis-Resistance in Chronic Lymphocytic Leukemia Expressing Zap-70.

Unraveling STAT Signaling in NPM/ALK-Induced Lymphoma: STAT3 but Not STAT5 Is Required for Lymphomagenesis in a Bone Marrow Transplantation Model Using Conditional Knockout Mice.

Inhibition of Protein Kinase C (PKC) delta with Rottlerin Induces Apoptosis in B-CLL Cells, Augments Chemotherapeutic Cytotoxicity and Inhibits Antiapoptotic Survival Signals.

Rapamycin-induced G 1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin

Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cδ

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American Society of Hematology

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American Society of Hematology

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