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Journal Articles

RNA-Binding Protein RBM5 Plays an Essential Role in Acute Myeloid Leukemia By Activating the Oncogenic Protein HOXA9

Mengli Zhang, Shaela Wright, Xiaowen Chen, Ye Xin, Yingcai Jin, Jianxiang Zhang, Xue Yang, Xinfeng Chen, Judith Hyle, Wojciech Rosikiewicz, Beisi Xu, Liusheng He, Feiqiu Wen, Chunliang Li, Peng Xu

Blood (2023) 142 (Supplement 1): 4130.

https://doi.org/10.1182/blood-2023-182595

Published: 2023

Journal Articles

Non-Canonical Transcription Activator Activity of RNA-Binding Protein MBNL1 Uniquely Controls FLT3 expression in MLL-Rearranged Leukemias

Siqi Yi, Shaela Wright, Meixia Che, Judith Hyle, Shelby Mryncza, Beisi Xu, Yong Cheng, Yajun Jiang, Chunliang Li

Blood (2023) 142 (Supplement 1): 2760.

https://doi.org/10.1182/blood-2023-185123

Published: 2023

Journal Articles

Activating a Non-Genetic MYC-Regulating Pathway Sensitizes Acute Myeloid Leukemia to Bromodomain Inhibition

Xinyue Zhou, Steven Moreira, Hong Wang, Pengcheng Zhang, Yang Zhou, Ravi Bhatia, Chunliang Li, Kristin Hope, Rui Lu

Blood (2022) 140 (Supplement 1): 8735.

https://doi.org/10.1182/blood-2022-167049

Published: 2022

Journal Articles

Genetic and Epigenetic Cis -Regulatory Disruptions Impacting the Canonical Wnt Signaling Repressor TLE1 Gene Promote Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia

Brennan P. Bergeron, Jonathan D. Diedrich, Yang Zhang, Kelly R. Barnett, Qian Dong, Daniel Ferguson, Robert J Autry, Wenjian Yang, Baranda S Hansen, Colton A Smith, Kristine R. Crews, Yiping Fan, Ching-Hon Pui, Shondra Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic

Blood (2022) 140 (Supplement 1): 8838–8839.

https://doi.org/10.1182/blood-2022-166973

Published: 2022

Journal Articles

ETV6 Represses TNF during Stress Hematopoiesis and Regulates HSC Self Renewal

Mackenzie Bloom, Rebekah Baskin-Doerfler, Ninad Oak, Ruopeng Feng, Xujie Zhao, Chunliang Li, Patrick Ozark, Katherine Verbist, Alexa Stroh, Sabrin Albeituni, JaQuel Maise, Mitchell J. Weiss, Shannon McKinney-Freeman, Jun J.J. Yang, Kim E. Nichols

Blood (2022) 140 (Supplement 1): 2849–2850.

https://doi.org/10.1182/blood-2022-168076

Published: 2022

Journal Articles

Systematically Interrogating Downstream Regulation Mechanisms of HOXA9 in MLL-r Leukemia Via Functional Noncoding CRISPR Screens

Chunliang Li, Shaela Wright, Xuijie Zhao, Shelby Mryncza, Beisi Xu

Blood (2022) 140 (Supplement 1): 1269–1270.

https://doi.org/10.1182/blood-2022-159186

Published: 2022

Journal Articles

Interrogating Novel Bromodomain Inhibition Resistance Mechanism in Mllr Leukemia

Chunliang Li, Shaela Wright, Jianzhong Hu, Yang Zhang, Judith Hyle, Rui Lu

Blood (2021) 138 (Supplement 1): 26.

https://doi.org/10.1182/blood-2021-147003

Published: 2021

Journal Articles

Mapping the Glucocorticoid Gene Regulatory Network and Alterations That Contribute to Steroid Resistance in Childhood Acute Lymphoblastic Leukemia

Brennan P. Bergeron, Jonathan Diedrich, Yang Zhang, Qian Dong, Daniel Ferguson, Robert J Autry, Wenjian Yang, Baranda S Hansen, Kristine R. Crews, Ching-Hon Pui, Yiping Fan, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic

Blood (2021) 138 (Supplement 1): 674.

https://doi.org/10.1182/blood-2021-153002

Published: 2021

Journal Articles

Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System

Ruopeng Feng, Thiyagaraj Mayuranathan, Peng Huang, Phillip A Doerfler, Yichao Li, Yu Yao, Jingjing Zhang, Lance E. Palmer, Peng Xu, Kalin Mayberry, Shaela Wright, Chunliang Li, Yong Cheng, Gerd A. Blobel, M. Celeste Simon, Mitchell J. Weiss

Blood (2021) 138 (Supplement 1): 574.

https://doi.org/10.1182/blood-2021-149901

Published: 2021

Journal Articles

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis

Blood (2021) 137 (2): 155–167.

https://doi.org/10.1182/blood.2020007809

Published: 2021

Includes: Supplemental data

Journal Articles

Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia

Blood (2019) 134 (Supplement_1): 650.

https://doi.org/10.1182/blood-2019-125791

Published: 2019

Journal Articles

The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation

Ruopeng Feng, PhD, Phillip A Doerfler, PhD, Yu Yao, MD, Xing Tang, PhD, Yong-Dong Wang, PhD, Chunliang Li, PhD, David E. Root, PhD, Yong Cheng, PhD, Mitchell J. Weiss, MD PhD

Blood (2018) 132 (Supplement 1): 410.

https://doi.org/10.1182/blood-2018-99-115589

Published: 2018

Journal Articles

FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1

Peng Xu, PhD, Daniel C. Scott, PhD, Xing Tang, PhD, Yu Yao, MD, Yong-Dong Wang, PhD, Wenjian Bi, PhD, Lance E. Palmer, PhD, Ruopeng Feng, PhD, Arno F. Alpi, PhD, Chunliang Li, PhD, Yong Cheng, PhD, Brenda A. Schulman, PhD, Mitchell J. Weiss, MD PhD

Blood (2018) 132 (Supplement 1): 529.

https://doi.org/10.1182/blood-2018-99-117362

Published: 2018

Journal Articles

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Blood (2017) 129 (24): 3264–3268.

https://doi.org/10.1182/blood-2017-03-771162

Published: 2017

Includes: Supplemental data

Journal Articles

Genome Editing Recreates Hereditary Persistence of Fetal Hemoglobin in Primary Human Erythroblasts

Elizabeth Traxler, Yu Yao, MD, Chunliang Li, Jeremy Grevet, Peng Huang, PhD, Shaela Wright, Gerd A. Blobel, MD PhD, Mitchell J. Weiss, MD PhD

Blood (2015) 126 (23): 640.

https://doi.org/10.1182/blood.V126.23.640.640

Published: 2015

NARROW

RNA-Binding Protein RBM5 Plays an Essential Role in Acute Myeloid Leukemia By Activating the Oncogenic Protein HOXA9

Non-Canonical Transcription Activator Activity of RNA-Binding Protein MBNL1 Uniquely Controls FLT3 expression in MLL-Rearranged Leukemias

Activating a Non-Genetic MYC-Regulating Pathway Sensitizes Acute Myeloid Leukemia to Bromodomain Inhibition

Genetic and Epigenetic Cis -Regulatory Disruptions Impacting the Canonical Wnt Signaling Repressor TLE1 Gene Promote Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia

ETV6 Represses TNF during Stress Hematopoiesis and Regulates HSC Self Renewal

Systematically Interrogating Downstream Regulation Mechanisms of HOXA9 in MLL-r Leukemia Via Functional Noncoding CRISPR Screens

Interrogating Novel Bromodomain Inhibition Resistance Mechanism in Mllr Leukemia

Mapping the Glucocorticoid Gene Regulatory Network and Alterations That Contribute to Steroid Resistance in Childhood Acute Lymphoblastic Leukemia

Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis

Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia

The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation

FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Genome Editing Recreates Hereditary Persistence of Fetal Hemoglobin in Primary Human Erythroblasts

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American Society of Hematology

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ASH Publications

American Society of Hematology

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