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Journal Articles

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V. Grinev, Anetta Ptasinska, Paulynn S. Chin, Claus Meyer, Sirintra Nakjang, Jayne Y. Hehir-Kwa, Daniel Williamson, Pierre Cauchy, Peter Keane, Salam A. Assi, Minoo Ashtiani, Sophie G. Kellaway, Maria R. Imperato, Fotini Vogiatzi, Elizabeth K. Schweighart, Shan Lin, Mark Wunderlich, Janine Stutterheim, Alexander Komkov, Elena Zerkalenkova, Paul Evans, Hesta McNeill, Alex Elder, Natalia Martinez-Soria, Sarah E. Fordham, Yuzhe Shi, Lisa J. Russell, Deepali Pal, Alex Smith, Zoya Kingsbury, Jennifer Becq, Cornelia Eckert, Oskar A. Haas, Peter Carey, Simon Bailey, Roderick Skinner, Natalia Miakova, Matthew Collin, Venetia Bigley, Muzlifah Haniffa, Rolf Marschalek, Christine J. Harrison, Catherine A. Cargo, Denis Schewe, Yulia Olshanskaya, Michael J. Thirman, Peter N. Cockerill, James C. Mulloy, Helen J. Blair, Josef Vormoor, James M. Allan, Constanze Bonifer, Olaf Heidenreich, Simon Bomken

Blood (2022) 140 (17): 1875–1890.

https://doi.org/10.1182/blood.2021015036

Published: 2022

Includes: Supplemental data

Journal Articles

Meta-Analysis of Genome-Wide Association Studies of Acute Myeloid Leukemia (AML) Patients Identifies Variants Associated with Risk of 11q23/ KMT2A -Translocated and Core-Binding Factor (CBF) AML and Suggests a Role for Transcription Elongation in Leukemogenesis

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-141653

Published: 2020

Journal Articles

Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia

Blood (2019) 134 (Supplement_1): 650.

https://doi.org/10.1182/blood-2019-125791

Published: 2019

Journal Articles

Multicentre Genome Wide Association Study Identifies Risk Alleles for Progressive Chronic Lymphocytic Leukaemia

Blood (2019) 134 (Supplement_1): 1740.

https://doi.org/10.1182/blood-2019-122037

Published: 2019

Journal Articles

Mutant TET2 Allele Dosage Affects Response to 5-Azacitidine in Acute Myeloid Leukemia

Blood (2019) 134 (Supplement_1): 113.

https://doi.org/10.1182/blood-2019-123047

Published: 2019

Journal Articles

Genetic susceptibility to breast cancer in lymphoma survivors

James M. Allan

Blood (2019) 133 (10): 1004–1006.

https://doi.org/10.1182/blood-2019-01-894279

Published: 2019

Journal Articles

Genome Wide Association Analyses Identify Pleiotropic Variants Associated with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Susceptibility

Blood (2018) 132 (Supplement 1): 1500.

https://doi.org/10.1182/blood-2018-99-110372

Published: 2018

Journal Articles

Inhibition of ATR in Combination with Nucleoside Analogues Eradicates Acute Myeloid Leukaemia in an Orthotopic Murine Xenograft Model

Sarah E Fordham, PhD, Helen J Blair, PhD, Claire J Elstob, PhD, Deepali Pal, PhD, Nicola Curtin, PhD, Paul Milne, PhD, Matthew Collin, MD PhD, Graham H Jackson, MD MBBS, Helen J Marr, MD PhD, Olaf Heidenreich, PhD, Ruth Plummer, John Pollard, PhD, Tobias F. Menne, MD PhD FRCPath, Gail L Jones, MD BMBS, James M Allan, DPhil

Blood (2016) 128 (22): 4031.

https://doi.org/10.1182/blood.V128.22.4031.4031

Published: 2016

Journal Articles

Targeting Ikkα in CLL: Inhibition of Non-Canonical NF-κb Signaling Decreases Survival and Proliferation of CD40L-Stimulated Primary CLL Cells

Elaine Willmore, PhD, Aaron Gardner, PhD, Susan J Tudhope, PhD, Andrew Herridge, BSc, Jill Hunter, Jonathan P Wallis, MD, Helen J Marr, MD PhD, Giacomo Berretta, PhD, David Breen, PhD, Andrew Paul, PhD, Darren Edwards, PhD, Louise C Young, PhD, Colin J Suckling, PhD, Robin Plevin, PhD, Marie Boyd, PhD, James M Allan, DPhil, Simon Mackay, PhD, Neil D Perkins, PhD

Blood (2016) 128 (22): 3959.

https://doi.org/10.1182/blood.V128.22.3959.3959

Published: 2016

Journal Articles

Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype

Blood (2013) 122 (19): 3298–3307.

https://doi.org/10.1182/blood-2013-03-491316

Published: 2013

Includes: Supplemental data

Journal Articles

A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia

Nicola J. Sunter, Kathryn Scott, Robert Hills, David Grimwade, Sheila Taylor, Lisa J. Worrillow, Sarah E. Fordham, Victoria J. Forster, Graham Jackson, Simon Bomken, Gail Jones, James M. Allan

Blood (2012) 119 (1): 196–205.

https://doi.org/10.1182/blood-2011-04-349803

Published: 2012

Includes: Supplemental data

Journal Articles

The Angiogenic Factor Angiopoietin-1 Is Regulated by the Acute Myeloid Leukemia Fusion Protein AML1/ETO

Victoria J Forster, Patricia Garrido Castro, Dipl.-Biochem., Amy K Bradburn, James M Allan, DPhil, Olaf Heidenreich, PhD

Blood (2011) 118 (21): 2426.

https://doi.org/10.1182/blood.V118.21.2426.2426

Published: 2011

Journal Articles

AML1/ETO Confers a Mutator Phenotype In Acute Myeloid Leukemia Associated with Downregulation of the Base-Excision-Repair Gene OGG1 ,

Victoria J Forster, Andrea Beyerle, PhD, Olaf Heidenreich, PhD, James M Allan, DPhil

Blood (2011) 118 (21): 3441.

https://doi.org/10.1182/blood.V118.21.3441.3441

Published: 2011

Journal Articles

MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia

Fay J. Hosking, Stephen Leslie, Alexander Dilthey, Loukas Moutsianas, Yufei Wang, Sara E. Dobbins, Elli Papaemmanuil, Eamonn Sheridan, Sally E. Kinsey, Tracy Lightfoot, Eve Roman, Julie A. E. Irving, James M. Allan, Malcolm Taylor, Mel Greaves, Gilean McVean, Richard S. Houlston

Blood (2011) 117 (5): 1633–1640.

https://doi.org/10.1182/blood-2010-08-301598

Published: 2011

Includes: Supplemental data

Journal Articles

A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia

Nicola J Sunter, Kathryn Scott, Robert Hills, David Grimwade, Sheila Taylor, Lisa Worrillow, Graham Jackson, Simon Bomken, Gail Jones, James M. Allan

Blood (2010) 116 (21): 756.

https://doi.org/10.1182/blood.V116.21.756.756

Published: 2010

Journal Articles

The t(8;21) Fusion Protein AML1/ETO Promotes Susceptibility to Mutation In Acute Myeloid Leukemia.

Victoria J Forster, James M. Allan, Olaf Heidenreich

Blood (2010) 116 (21): 3368.

https://doi.org/10.1182/blood.V116.21.3368.3368

Published: 2010

Journal Articles

Cellular Response to Cytarabine Is Modulated by the DNA Mismatch Repair Pathway: Implications for Treatment of Acute Myeloid Leukemia

Sarah E Fordham, Elizabeth C Matheson, Kathryn Scott, Julie Irving, James M Allan

Blood (2010) 116 (21): 1819.

https://doi.org/10.1182/blood.V116.21.1819.1819

Published: 2010

Journal Articles

Mature MicroRNAs Mir-18, -19a, -19b, -17-5p and -92 of the Mir-17-92 Cluster Predict for Treatment Free Survival In Patients with Chronic Lymphocytic Leukaemia

Rachel E. Culpin, BSc, (Hons), Kim Pearce, PhD, James R. Bailey, MD, PhD, Nicola J. Sunter, PhD, Joanna C. Pointon, PhD, Stephen J. Proctor, MD, David J. Allsup, PhD, MRCP, FRCPath, James M. Allan, PhD, Tryfonia Mainou-Fowler, PhD

Blood (2010) 116 (21): 2727.

https://doi.org/10.1182/blood.V116.21.2727.2727

Published: 2010

Journal Articles

Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk

Fay J. Hosking, Elli Papaemmanuil, Eammon Sheridan, Sally E. Kinsey, Tracy Lightfoot, Eve Roman, Julie A. E. Irving, James M. Allan, Malcolm Taylor, Ian P. Tomlinson, Mel Greaves, Richard S. Houlston

Blood (2010) 115 (22): 4472–4477.

https://doi.org/10.1182/blood-2009-09-244483

Published: 2010

Includes: Supplemental data

Journal Articles

Genetic variation in the folate metabolic pathway and risk of childhood leukemia

Tracy J. Lightfoot, W. Thomas Johnston, Dan Painter, Jill Simpson, Eve Roman, Chris F. Skibola, Martyn T. Smith, James M. Allan, G. Malcolm Taylor

Blood (2010) 115 (19): 3923–3929.

https://doi.org/10.1182/blood-2009-10-249722

Published: 2010

NARROW

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Meta-Analysis of Genome-Wide Association Studies of Acute Myeloid Leukemia (AML) Patients Identifies Variants Associated with Risk of 11q23/ KMT2A -Translocated and Core-Binding Factor (CBF) AML and Suggests a Role for Transcription Elongation in Leukemogenesis

Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia

Multicentre Genome Wide Association Study Identifies Risk Alleles for Progressive Chronic Lymphocytic Leukaemia

Mutant TET2 Allele Dosage Affects Response to 5-Azacitidine in Acute Myeloid Leukemia

Genetic susceptibility to breast cancer in lymphoma survivors

Genome Wide Association Analyses Identify Pleiotropic Variants Associated with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Susceptibility

Inhibition of ATR in Combination with Nucleoside Analogues Eradicates Acute Myeloid Leukaemia in an Orthotopic Murine Xenograft Model

Targeting Ikkα in CLL: Inhibition of Non-Canonical NF-κb Signaling Decreases Survival and Proliferation of CD40L-Stimulated Primary CLL Cells

Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype

A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia

The Angiogenic Factor Angiopoietin-1 Is Regulated by the Acute Myeloid Leukemia Fusion Protein AML1/ETO

AML1/ETO Confers a Mutator Phenotype In Acute Myeloid Leukemia Associated with Downregulation of the Base-Excision-Repair Gene OGG1 ,

MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia

A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia

The t(8;21) Fusion Protein AML1/ETO Promotes Susceptibility to Mutation In Acute Myeloid Leukemia.

Cellular Response to Cytarabine Is Modulated by the DNA Mismatch Repair Pathway: Implications for Treatment of Acute Myeloid Leukemia

Mature MicroRNAs Mir-18, -19a, -19b, -17-5p and -92 of the Mir-17-92 Cluster Predict for Treatment Free Survival In Patients with Chronic Lymphocytic Leukaemia

Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk

Genetic variation in the folate metabolic pathway and risk of childhood leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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