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Stephanie M. Dobson
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Journal Articles

Mir-125b Regulates the Self-Renewal of Acute Myeloid Leukemia Stem Cells through PTPN18 and GSK3

Qiang Liu, PhD BSc, Olga I. Gan, PhD, Gabriela Krivdova, BSc, Aaron Trotman-Grant, Stephanie M. Dobson, PhD, Karin G. Hermans, Mark D. Minden, Shai Izraeli, MD, John E. Dick, PhD FRS, Jean C.Y. Wang, MD PhD, Eric R. Lechman,, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-141733
Published: 2020
Journal Articles

Genetic Analysis of B-Cell Acute Lymphoblastic Leukemia Dissemination to the Central Nervous System Identifies Clonal Selection and Therapeutic Vulnerability

Robert Vanner, MD PhD, Stephanie M. Dobson, PhD, Ildiko Grandal, MSc, Olga I. Gan, PhD, Jessica McLeod, BSc, James Kennedy, MD PhD, Veronique Voisin, PhD, Cynthia Guidos, PhD, Jayne S. Danska, PhD, Esme Waanders, PhD, Mark D. Minden, MD PhD, Charles G. Mullighan, MBBS, MD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1542.
https://doi.org/10.1182/blood-2018-99-115191
Published: 2018
Journal Articles

Relapse-Initiating Clones Preexisting at Diagnosis in B- Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse

Laura Garcia Prat, Stephanie M. Dobson, PhD, Michelle Chan-Seng-Yue, Robert Vanner, MD PhD, Alex Murison, Jeffery Wintersinger, Esme Waanders, PhD, Olga I. Gan, PhD, Jessica McLeod, BSc, Debbie Payne-Turner, Michael Edmonson, Zhaohui Gu, PhD, Xiaotu Ma, Yiping Fan, Pankaj Gupta, Michael Rusch, BS, Ying Shao, John Easton, PhD, Jinghui Zhang, Mark D. Minden, MD PhD, Quaid Morris, Mathieu Lupien, Charles G. Mullighan, MBBS, MD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 915.
https://doi.org/10.1182/blood-2018-99-118998
Published: 2018
Journal Articles

Isolation of CD34 − and CD34 + Leukemia Stem Cells from Acute Myeloid Leukemia Blasts Using CD200

Jenny M. Ho, MD, Stephanie M. Dobson, PhD, Jessica McLeod, BSc, Veronique Voisin, PhD, Alex Murison, James Kennedy, MD PhD, Sasan Zandi, MD PhD, Kolja Eppert, MSc, PhD, Mark D. Minden, MD PhD, Mathieu Lupien, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2790.
https://doi.org/10.1182/blood-2018-99-119318
Published: 2018
Journal Articles

Inactivation of Stage-Specific B-Cell Commitment Genes Generates Distinct Molecular Subtypes of BCR-ABL1 Lymphoblastic Leukemia

Jaeseung C. Kim, MSc, Michelle Chan-Seng-Yue, Gavin W. Wilson, PhD, Andrea Arruda, Karen Ng, Olga I. Gan, PhD, Stephanie M. Dobson, PhD, Paul M. Krzyzanowski, PhD, Johann K. Hitzler, MD, Anne Tierens, MD PhD, John E. Dick, PhD, Mark D. Minden, MD PhD, John D. McPherson, PhD, Faiyaz Notta, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 569.
https://doi.org/10.1182/blood-2018-99-116981
Published: 2018
Journal Articles

Distinct patterns of clonal evolution in patients with concurrent myelo- and lymphoproliferative neoplasms

James A. Kennedy, Jessie J. F. Medeiros, Stephanie M. Dobson, Andrea Arruda, Mahadeo A. Sukhai, Tracy Stockley, Anne Tierens, Mark D. Minden, Suzanne Kamel-Reid, John E. Dick, Vikas Gupta
Journal: Blood
Blood (2018) 132 (20): 2201–2205.
https://doi.org/10.1182/blood-2018-04-845065
Published: 2018
Includes: Supplemental data
Journal Articles

Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse

Stephanie M. Dobson, Esme Waanders, PhD, Robert Vanner, PhD, Olga I Gan, PhD, Jessica McLeod, Ildiko Grandal, MSc, Debbie Payne-Turner, BA, Michael Edmonson, PhD, Zhaohui Gu, PhD, Xiaotu Ma, PhD, Yiping Fan, Sagi Abelson, PhD, Pankaj Gupta, Michael Rusch, Ying Shao, Lei Shi, PhD, Stanley Pounds, PhD, Scott Olsen, Geoffrey A. Neale, PhD, John Easton, PhD, Cynthia J. Guidos, PhD, Jayne S. Danska, PhD, Jinghui Zhang, PhD, Mark D. Minden, MD PhD, Charles G. Mullighan, MBBS(Hons), MSc, MD, John E. Dick, PhD
Journal: Blood
Blood (2016) 128 (22): 605.
https://doi.org/10.1182/blood.V128.22.605.605
Published: 2016
Journal Articles

CD200 Is a Marker of LSC Activity in Acute Myeloid Leukemia

Jenny M. Ho, MD, Stephanie M. Dobson, Jessica McLeod, Liqing Jin, MD PhD, Stanley W.K. Ng, MSc, Amanda Mitchell, PhD, Liran I. Shlush, MD PhD, Sasan Zandi, MD PhD, Kolja Eppert, PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1705.
https://doi.org/10.1182/blood.V128.22.1705.1705
Published: 2016
Journal Articles

The Human Blood Hierarchy Is Shaped By Distinct Progenitor Lineages Across Development

Sasan Zandi, MDPhD, Faiyaz Notta, John E. Dick, PhD, Naoya Takayama, Stephanie M Dobson, MSc, Olga I Gan, PhD, Gavin Wilson, Kerstin Kaufmann, Jessica McLeod, Elisa Laurenti, PhD, Cyrille Dunant, Mcpherson John, Lincoln Stein, Yigal Dror, MD FRCP(C)
Journal: Blood
Blood (2015) 126 (23): 2360.
https://doi.org/10.1182/blood.V126.23.2360.2360
Published: 2015
Journal Articles

Mir-125a Confers Multi-Lineage Long-Term Repopulating Stem Cell Activity to Human Hematopoietic Committed Progenitors

Eric R. Lechman, PhD, Karin G. Hermans, PhD, Erwin M. Schoof, PhD, Aaron Trotman-Grant, BS, Stephanie M Dobson, MSc, Gabriela Krivdova, MS, Janneke J. Elzinga, James A. Kennedy, MDPhD, Olga I Gan, PhD, John E Dick, PhD
Journal: Blood
Blood (2015) 126 (23): 900.
https://doi.org/10.1182/blood.V126.23.900.900
Published: 2015
Journal Articles

Genomic Landscape of Relapsed Acute Lymphoblastic Leukemia

Esmé Waanders, PhD, Stephanie M Dobson, MSc, Xiaotu Ma, PhD, Debbie Payne-Turner, BS, Guangchun Song, PhD, Yiping Fan, Zhaohui Gu, PhD, Ying Shao, Michael Rusch, BA, Kelly McCastlain, BS, Ilaria Iacobucci, PhD, Kathryn G. Roberts, Shann-Ching Chen, PhD, Pankaj Gupta, Ji Wen, Gang Wu, PhD, Jing Ma, PhD, Colin Bailey, Matthew Lear, Scott Olsen, Deanna Naeve, Geoffrey A. Neale, PhD, John Easton, PhD, Sima Jeha, MD, Ching-Hon Pui, MD, James R. Downing, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Jun J Yang, PhD, John E. Dick, PhD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MSc, MD
Journal: Blood
Blood (2015) 126 (23): 692.
https://doi.org/10.1182/blood.V126.23.692.692
Published: 2015
Journal Articles

Modeling the Multi-Step Pathogenesis of Acute Myeloid Leukemia of Down Syndrome

Eric R. Lechman, PhD, Karin G. Hermans, PhD, Stephanie M. Dobson, BSc, Olga I. Gan, PhD, James A. Kennedy, MDPhD, John Chen, PhD, Johann K. Hitzler, MD, John E. Dick, PhD
Journal: Blood
Blood (2014) 124 (21): 3579.
https://doi.org/10.1182/blood.V124.21.3579.3579
Published: 2014
Journal Articles

Enforced Expression Of Mir-125b Promotes the in vivo expansion Of Human Lin neg cord Blood Multi-Lymphoid Progenitors and Leukemia Stem Cells

Karin G. Hermans, PhD, Eric R. Lechman, PhD, Stephanie M. Dobson, BSc, Mark D. Minden, MD PhD, John E. Dick, PhD
Journal: Blood
Blood (2013) 122 (21): 1648.
https://doi.org/10.1182/blood.V122.21.1648.1648
Published: 2013
Journal Articles

Defining Functional Heterogeneity In Acute Lymphoblastic Leukemia

Stephanie M. Dobson, BSc, Esmé Waanders, PhD, Jessica McLeod, Ildiko Grandal, Olga I. Gan, PhD, Faiyaz Notta, PhD, Jessica Loo-Young-Kee, Mark D. Minden, MD PhD, Cynthia J. Guidos, PhD, Jayne S. Danska, PhD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, John E. Dick, PhD
Journal: Blood
Blood (2013) 122 (21): 1365.
https://doi.org/10.1182/blood.V122.21.1365.1365
Published: 2013