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Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescuing and cancer mutations

Blood blood.2024025023.

https://doi.org/10.1182/blood.2024025023

Published: 2024

Includes: Supplemental data

Journal Articles

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Hiroki Mizumaki, Shouguo Gao, Zhijie Wu, Emma M. Groarke, Lemlem Alemu, Diego Quinones Raffo, Olga Rios, Sachiko Kajigaya, Bhavisha A. Patel, Neal S. Young

Blood (2023) 142 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2023-181078

Published: 2023

Journal Articles

Distinct Immune and Molecular Profiles of Hepatitis-Associated Aplastic Anemia

Roma V. Rajput, Dalton Hironaka, Ruba Shalhoub, Lemlem Alemu, Emma M. Groarke, Jennifer Lotter, Olga Rios, Ivana Darden, Colin O. Wu, Fernanda Gutierrez-Rodrigues, Xingmin Feng, Neal S. Young, Bhavisha A. Patel

Blood (2023) 142 (Supplement 1): 1340.

https://doi.org/10.1182/blood-2023-180902

Published: 2023

Journal Articles

Spectrum of clonal hematopoiesis in VEXAS syndrome

Blood (2023) 142 (3): 244–259.

https://doi.org/10.1182/blood.2022018774

Published: 2023

Includes: Supplemental data

Journal Articles

CBFB-MYH11 Is Required for the Maintenance of Inv(16) AML

Sipra Panda, Yiqian Wang, Lisa Richter, Michelle Becker, Lisa J Garrett, Cecilia Rivas, Lemlem Alemu, Ling Zhao, Paul P. Liu, R. Katherine Hyde

Blood (2022) 140 (Supplement 1): 2995–2996.

https://doi.org/10.1182/blood-2022-169475

Published: 2022

Journal Articles

HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia

Yoshitaka Zaimoku, Bhavisha A. Patel, Sharon D. Adams, Ruba Shalhoub, Emma M. Groarke, Audrey Ai Chin Lee, Sachiko Kajigaya, Xingmin Feng, Olga Julia Rios, Holly Eager, Lemlem Alemu, Diego Quinones Raffo, Colin O. Wu, Willy A. Flegel, Neal S. Young

Blood (2021) 138 (26): 2799–2809.

https://doi.org/10.1182/blood.2021012895

Published: 2021

Includes: Supplemental data

Journal Articles

Clonal Hematopoiesis in Telomere Biology Disorders Associates with the Underlying Germline Defect and Somatic Mutations in POT1 , PPM1D, and TERT promoter

Fernanda Gutierrez-Rodrigues, Emma M Groarke, Diego V Clé, Bhavisha A. Patel, Flávia S Donaires, Nina Spitofsky, Lemlem Alemu, Bárbara A Santana, Sachiko Kajigaya, Simona Colla, Michel Michels De Oliveira, Carmem M. S. Bonfim, Rodrigo T. Calado, Neal S. Young

Blood (2021) 138 (Supplement 1): 1111.

https://doi.org/10.1182/blood-2021-151199

Published: 2021

Journal Articles

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development

Tao Zhen, Yaqiang Cao, Gang Ren, Ling Zhao, R. Katherine Hyde, Guadalupe Lopez, Dechun Feng, Lemlem Alemu, Keji Zhao, P. Paul Liu

Blood (2020) 136 (21): 2373–2385.

https://doi.org/10.1182/blood.2020007747

Published: 2020

Includes: Supplemental data

Journal Articles

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Bhavisha A Patel, MD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 1219.

https://doi.org/10.1182/blood-2019-127053

Published: 2019

Journal Articles

Analysis of Deficiency of Adenosine Deaminase 2 Pathogenesis Based on Single Cell RNA Sequencing of Monocytes

Naoki Watanabe, Shouguo Gao, PhD, Sachiko Kajigaya, Carrie Diamond, MD, Lemlem Alemu, BS, Amanda Ombrello, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 2317.

https://doi.org/10.1182/blood-2019-123859

Published: 2019

Journal Articles

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Sharon D. Adams, MT, CHS (ABHI), Bhavisha A Patel, MD, Audrey Ai Chin Lee, MS, CHT (ABHI), Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Olga Rios, RN, Holly DiFebo, RN, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Willy A. Flegel, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3738.

https://doi.org/10.1182/blood-2019-127359

Published: 2019

Journal Articles

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Shouguo Gao, PhD, Zhijie Wu, MD PhD, Carrie Diamond, MD, Bradley Arnold, BS, Valentina Giudice, MD, Lemlem Alemu, BS, John Barrett, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2404.

https://doi.org/10.1182/blood-2018-99-115166

Published: 2018

Journal Articles

Title: Runx1 Is Indispensable for Leukemia Development Induced By Cbfb-MYH11

Tao Zhen, PhD, Erika Mijin Kwon, PhD, R. Katherine Hyde, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Lemlem Alemu, BS, Paul P Liu, MD PhD

Blood (2018) 132 (Supplement 1): 1337.

https://doi.org/10.1182/blood-2018-99-116930

Published: 2018

Journal Articles

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

Tao Zhen, Erika M. Kwon, Ling Zhao, Jingmei Hsu, R. Katherine Hyde, Ying Lu, Lemlem Alemu, Nancy A. Speck, P. Paul Liu

Blood (2017) 130 (22): 2431–2442.

https://doi.org/10.1182/blood-2017-04-780106

Published: 2017

Includes: Supplemental data

Journal Articles

RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

Yiqian Wang, Kira Hannon, Lisa Richter, Michelle Becker, Lisa Garett, Cecilia Rivas, Lemlem Alemu, Ling Zhao, MD PhD, Pu Paul Liu, MD PhD, R. Katherine Hyde, PhD

Blood (2016) 128 (22): 2715.

https://doi.org/10.1182/blood.V128.22.2715.2715

Published: 2016

Journal Articles

Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development

Tao Zhen, PhD, Erika Mijin Kwon, PhD, R. Katherine Hyde, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Lemlem Alemu, Pu Paul Liu, MD PhD

Blood (2016) 128 (22): 2722.

https://doi.org/10.1182/blood.V128.22.2722.2722

Published: 2016

Journal Articles

CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis

Tao Zhen, PhD, Ling Zhao, MD PhD, R. Katherine Hyde, PhD, Lemlem Alemu, Pu Paul Liu, MD PhD

Blood (2015) 126 (23): 3662.

https://doi.org/10.1182/blood.V126.23.3662.3662

Published: 2015

Journal Articles

The Multimerization Domain of Cbfß-SMMHC Is Required for Leukemogenesis

Ling Zhao, MD PhD, Lemlem Alemu, Jun Cheng, Tao Zhen, PhD, Alan D. Friedman, MD, Pu Paul Liu, MD PhD

Blood (2015) 126 (23): 3666.

https://doi.org/10.1182/blood.V126.23.3666.3666

Published: 2015

Journal Articles

Functional Dissection of the C Terminus of CBFβ-SMMHC Indicates a Critical Role of the Multimerization Domain during Hematopoiesis and Leukemogenesis

Ling Zhao, MD PhD, Lemlem Alemu, Jun Cheng, Tao Zhen, PhD, Alan D. Friedman, MD, Pu Paul Liu, MD PhD

Blood (2014) 124 (21): 2218.

https://doi.org/10.1182/blood.V124.21.2218.2218

Published: 2014

Journal Articles

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

Yasuhiko Kamikubo, R. Katherine Hyde, Ling Zhao, Lemlem Alemu, Cecilia Rivas, Lisa J. Garrett, P. Paul Liu

Blood (2013) 121 (4): 638–642.

https://doi.org/10.1182/blood-2012-06-434688

Published: 2013

Includes: Supplemental data

NARROW

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescuing and cancer mutations

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Distinct Immune and Molecular Profiles of Hepatitis-Associated Aplastic Anemia

Spectrum of clonal hematopoiesis in VEXAS syndrome

CBFB-MYH11 Is Required for the Maintenance of Inv(16) AML

HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia

Clonal Hematopoiesis in Telomere Biology Disorders Associates with the Underlying Germline Defect and Somatic Mutations in POT1 , PPM1D, and TERT promoter

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Analysis of Deficiency of Adenosine Deaminase 2 Pathogenesis Based on Single Cell RNA Sequencing of Monocytes

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Title: Runx1 Is Indispensable for Leukemia Development Induced By Cbfb-MYH11

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development

CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis

The Multimerization Domain of Cbfß-SMMHC Is Required for Leukemogenesis

Functional Dissection of the C Terminus of CBFβ-SMMHC Indicates a Critical Role of the Multimerization Domain during Hematopoiesis and Leukemogenesis

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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