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Journal Articles

Megakaryocytes Have Immune Characteristics in Murine Immune Bone Marrow Failure

Ashvind Prabahran, Ash Lee Manley, Zhijie Wu, Shouguo Gao, Hiroki Mizumaki, Christian Combs, Jichun Chen, Xingmin Feng, Neal S. Young

Blood (2023) 142 (Supplement 1): 1349.

https://doi.org/10.1182/blood-2023-174597

Published: 2023

Journal Articles

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Hiroki Mizumaki, Shouguo Gao, Zhijie Wu, Emma M. Groarke, Lemlem Alemu, Diego Quinones Raffo, Olga Rios, Sachiko Kajigaya, Bhavisha A. Patel, Neal S. Young

Blood (2023) 142 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2023-181078

Published: 2023

Journal Articles

Single-cell genomics in acquired bone marrow failure syndromes

Zhijie Wu, Neal S. Young

Blood (2023) 142 (14): 1193–1207.

https://doi.org/10.1182/blood.2022018581

Published: 2023

Journal Articles

Efficacy of JAK1/2 inhibition in murine immune bone marrow failure

Emma M. Groarke, Xingmin Feng, Nidhi Aggarwal, Ash Lee Manley, Zhijie Wu, Shouguo Gao, Bhavisha A. Patel, Jichun Chen, Neal S. Young

Blood (2023) 141 (1): 72–89.

https://doi.org/10.1182/blood.2022015898

Published: 2023

Includes: Supplemental data

Journal Articles

Oligoclonal T-cell expansion in a patient with bone marrow failure after CD19 CAR-T therapy for Richter-transformed DLBCL

Kai Rejeski, Zhijie Wu, Viktoria Blumenberg, Wolfgang G. Kunz, Susanna Müller, Sachiko Kajigaya, Shouguo Gao, Veit L. Bücklein, Lisa Frölich, Christian Schmidt, Michael von Bergwelt-Baildon, Xingmin Feng, Neal S. Young, Marion Subklewe

Blood (2022) 140 (20): 2175–2179.

https://doi.org/10.1182/blood.2022017015

Published: 2022

Includes: Supplemental data

Journal Articles

JAK 1/2 Inhibition Preserves Hematopoietic Progenitor and Stem Cells, Prevents Aplasia, Inhibits Pro-Inflammatory Cytokines, and Prolongs Survival in Murine Immune Bone Marrow Failure

Emma M. Groarke, Xingmin Feng, Nidhi Aggarwal, Ash Lee Manley, Zhijie Wu, Shouguo Gao, Bhavisha A. Patel, Jichun Chen, Neal S. Young

Blood (2022) 140 (Supplement 1): 471–472.

https://doi.org/10.1182/blood-2022-159733

Published: 2022

Journal Articles

Granulocytic Myeloid-Derived Suppressor Cells in Murine Models of Immune-Mediated Bone Marrow Failure

Xingmin Feng, Jisoo Kim, Gladys Gonzalez Matias, Zhijie Wu, Sabrina Solorzano, Sai Batchu, Shouguo Gao, Jichun Chen, Neal S. Young

Blood (2021) 138 (Supplement 1): 2176.

https://doi.org/10.1182/blood-2021-148467

Published: 2021

Journal Articles

Somatic Mutations in a Single Residue of UBA1 Cause Vexas, a Severe Adult-Onset Rheumatic Disease Associated with Myeloid Dysplasia

David B. Beck, MDPhD, Zhijie Wu, MD, Bhavisha A Patel, MD, Marcela A Ferrada, MD, Keith A Sikora, MD, Amanda Ombrello, MD, Alina E. Dulau Florea, MD, Weixin Wang, PhD, Emma M. Groarke, MD, Shawn M. Burgess, PhD, Ivona A Aksentijevich, MD, Achim A Werner, PhD, Neal S. Young, MD, Katherine R. Calvo, MD PhD, Daniel L Kastner, MDPhD, Peter C Grayson, MD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-141949

Published: 2020

Journal Articles

Myelodysplasia and Bone Marrow Manifestations of Somatic UBA1 Mutated Autoinflammatory Disease

Ifeyinwa Emmanuela Obiorah, MBBS,PhD, David B. Beck, MDPhD, Weixin Wang, PhD, Amanda Ombrello, MD, Marcela A Ferrada, MD, Zhijie Wu, MD, Keith A Sikora, MD, Megan A Trick, Alina Dulau-Florea, MD, Bhavisha A Patel, MD, Emma Groarke, MD, Shawn M. Burgess, PhD, Achim A Werner, PhD, Ivona A Aksentijevich, MD, Neal S. Young, MD, Daniel L Kastner, MDPhD, Peter C Grayson, MD, Katherine R. Calvo, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-140480

Published: 2020

Journal Articles

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Xin Zhao, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Qingguo Liu, MD PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Fengkui Zhang, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 4997.

https://doi.org/10.1182/blood-2019-123249

Published: 2019

Journal Articles

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Shouguo Gao, PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3706.

https://doi.org/10.1182/blood-2019-123204

Published: 2019

Journal Articles

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Zhijie Wu, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Jinguo Chen, PhD, Rongye Shi, BS, Carrie Diamond, MD, Cindy Palmer, BSN, Amy P. Hsu, Katherine R. Calvo, MD PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3735.

https://doi.org/10.1182/blood-2019-124774

Published: 2019

Journal Articles

Macrophage TNF-α licenses donor T cells in murine bone marrow failure and can be implicated in human aplastic anemia

Wanling Sun, Zhijie Wu, Zenghua Lin, Maile Hollinger, Jichun Chen, Xingmin Feng, Neal S. Young

Blood (2018) 132 (26): 2730–2743.

https://doi.org/10.1182/blood-2018-05-844928

Published: 2018

Includes: Supplemental data

Journal Articles

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Shouguo Gao, PhD, Zhijie Wu, MD PhD, Carrie Diamond, MD, Bradley Arnold, BS, Valentina Giudice, MD, Lemlem Alemu, BS, John Barrett, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2404.

https://doi.org/10.1182/blood-2018-99-115166

Published: 2018

Journal Articles

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Xingmin Feng, PhD, Zenghua Lin, MD, Maile K. Hollinger, BA, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Kaylind Batey, BS, Keyvan Keyvanfar, BS, Jichun Chen, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 1310.

https://doi.org/10.1182/blood-2018-99-113488

Published: 2018

Journal Articles

Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS)

Alana Vicente, MD, Fernanda Gutierrez-Rodrigues, PhD, Valentina Giudice, MD, Zhijie Wu, MD PhD, Sachiko Kajigaya, PhD, Maria del Pilar Fernandez Ibanez, Maher Albitar, MD, Barbara Weinstein, RN, Katherine R. Calvo, MD PhD, Danielle M. Townsley, MDMSc, Phillip Scheinberg, MD, Cynthia E. Dunbar, MD, Neal S. Young, MD, Thomas Winkler, MD

Blood (2018) 132 (Supplement 1): 229.

https://doi.org/10.1182/blood-2018-99-119780

Published: 2018

Journal Articles

Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells

Xin Zhao, Shouguo Gao, Zhijie Wu, Sachiko Kajigaya, Xingmin Feng, Qingguo Liu, Danielle M. Townsley, James Cooper, Jinguo Chen, Keyvan Keyvanfar, Maria del Pilar Fernandez Ibanez, Xujing Wang, Neal S. Young

Blood (2017) 130 (25): 2762–2773.

https://doi.org/10.1182/blood-2017-08-803353

Published: 2017

Includes: Supplemental data

Journal Articles

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

Xingmin Feng, PhD, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Zenghua Lin, MD, Maile K Hollinger, BA, Jichun Chen, PhD, Neal S. Young, MD

Blood (2017) 130 (Supplement 1): 778.

https://doi.org/10.1182/blood.V130.Suppl_1.778.778

Published: 2017

Journal Articles

T Cells Trafficking to Bone Marrow Have Different Characteristics from Those to Other Organs in an Immune-Mediated Bone Marrow Failure Mouse Model

Zenghua Lin, MD, Xingmin Feng, PhD, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Maile K Hollinger, BA, Jichun Chen, PhD, Hong Liu, MD PhD, Neal S. Young, MD

Blood (2017) 130 (Supplement 1): 2455.

https://doi.org/10.1182/blood.V130.Suppl_1.2455.2455

Published: 2017

Journal Articles

Crispr/Cas9-Induced DNMT3A Mutations in the K562 Human Leukemic Cell Line As a Model of DNMT3A -Mutated Leukemogenesis

Lauren G. Banaszak, BS, Valentina Giudice, MD, Xin Zhao, MD PhD, Zhijie Wu, MD, Kohei Hosokawa, MD PhD, Keyvan Keyvanfar, BS, Danielle Townsley, MD, Sachiko Kajigaya, PhD, Neal S. Young

Blood (2016) 128 (22): 2704.

https://doi.org/10.1182/blood.V128.22.2704.2704

Published: 2016

NARROW

Megakaryocytes Have Immune Characteristics in Murine Immune Bone Marrow Failure

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Single-cell genomics in acquired bone marrow failure syndromes

Efficacy of JAK1/2 inhibition in murine immune bone marrow failure

Oligoclonal T-cell expansion in a patient with bone marrow failure after CD19 CAR-T therapy for Richter-transformed DLBCL

JAK 1/2 Inhibition Preserves Hematopoietic Progenitor and Stem Cells, Prevents Aplasia, Inhibits Pro-Inflammatory Cytokines, and Prolongs Survival in Murine Immune Bone Marrow Failure

Granulocytic Myeloid-Derived Suppressor Cells in Murine Models of Immune-Mediated Bone Marrow Failure

Somatic Mutations in a Single Residue of UBA1 Cause Vexas, a Severe Adult-Onset Rheumatic Disease Associated with Myeloid Dysplasia

Myelodysplasia and Bone Marrow Manifestations of Somatic UBA1 Mutated Autoinflammatory Disease

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Macrophage TNF-α licenses donor T cells in murine bone marrow failure and can be implicated in human aplastic anemia

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS)

Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

T Cells Trafficking to Bone Marrow Have Different Characteristics from Those to Other Organs in an Immune-Mediated Bone Marrow Failure Mouse Model

Crispr/Cas9-Induced DNMT3A Mutations in the K562 Human Leukemic Cell Line As a Model of DNMT3A -Mutated Leukemogenesis

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American Society of Hematology

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American Society of Hematology

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