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Journal Articles

Decoding DDX41: Clinical impact of germline and somatic mutations in 77 high-risk myeloid neoplasm patients

Talha Badar, Mahesh Kumar, Yael Kusne, Terra Lasho, James Foran, Hemant Murthy, Mohamed Kharfan-Dabaja, Timothy Chlon, Naseema Gangat, Hassan Alkhateeb, Abhishek Mangaonkar, Rong He, David Viswanatha, Jennifer Jiang, Yao-Shan Fan, Alejandro Ferrer, Mark Litzow, Aref Al-Kali, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 1442.

https://doi.org/10.1182/blood-2025-1442

Published: 2025

Journal Articles

Molecular association with elevated LDH levels in patients with AML

Oudai Alkabbani, Yazan Jabban, Rong He, David Viswanatha, Kurt Bessonen, Patricia Greipp, Dragan Jevremovic, Antoine Saliba, Mehrdad Hefazi Torghabeh, Aasiya Matin, William Hogan, Abhishek Mangaonkar, Hassan Alkhateeb, Mrinal Patnaik, Mithun Shah, Kebede Begna, Aref Al-Kali

Blood (2025) 146 (Supplement 1): 7039.

https://doi.org/10.1182/blood-2025-7039

Published: 2025

Journal Articles

Interplay between mutant DNMT3A and UBA1 worsens survival through altered inflammatory and metabolic pathways

Blood (2025) 146 (Supplement 1): 3191.

https://doi.org/10.1182/blood-2025-3191

Published: 2025

Journal Articles

Insights into clonal and CBC changes at disease evolution among ccus patients

Yazan Jabban, Rong He, Kurt Bessonen, Patricia Greipp, Dragan Jevremovic, David Viswanatha, James Foran, Talha Badar, Cecilia Arana Yi, Yael Kusne, Antoine Saliba, Mehrdad Hefazi Torghabeh, Aasiya Matin, William Hogan, Abhishek Mangaonkar, Mithun Shah, Hassan Alkhateeb, Mrinal Patnaik, Aref Al-Kali

Blood (2025) 146 (Supplement 1): 5621.

https://doi.org/10.1182/blood-2025-5621

Published: 2025

Journal Articles

Clinicopathologic features of myeloid neoplasms and pre-neoplasms with isolated ZRSR2 mutations

Alma Oskarsdottir, Rong He, Jennifer Jiang, Mahmoud Yacout, Patricia Greipp, Mithun Shah, Hassan Alkhateeb, David Viswanatha, Fiona Craig, Katalin Kelemen, Aref Al-Kali, Dragan Jevremovic

Blood (2025) 146 (Supplement 1): 7394.

https://doi.org/10.1182/blood-2025-7394

Published: 2025

Journal Articles

Prevalence, clinical correlates and clonal inferences of concurrent splicing factor mutations in patients with myeloid neoplasms

Nickolas Steinauer, Vihan Singh, Terra Lasho, Christy Finke, Alejandro Ferrer, Pankaj Pradeep, Jenna Fernandez, Clifford Csizmar, Aref Al-Kali, David Viswanatha, Rong He, Abhishek Mangaonkar, Xi Zhang, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 5650.

https://doi.org/10.1182/blood-2025-5650

Published: 2025

Journal Articles

Disease stage-specific mutational landscape in essential thrombocythemia and prognostic correlates: A Mayo Clinic study of 500 NGS-informative cases

Merry Nakhleh, Rong He, Priyansh Faldu, David Viswanatha, Kaaren Reichard, Cinthya Mendoza, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 3799.

https://doi.org/10.1182/blood-2025-3799

Published: 2025

Journal Articles

Clinical NGS detection of TP53 mutations in chronic phase primary myelofibrosis: Comparative analyses of genotype and prognosis

Blood (2025) 146 (Supplement 1): 3798.

https://doi.org/10.1182/blood-2025-3798

Published: 2025

Journal Articles

Causes of death in DDX41-mutated myeloid neoplasms: A retrospective study

Blood (2025) 146 (Supplement 1): 7370.

https://doi.org/10.1182/blood-2025-7370

Published: 2025

Journal Articles

Classic hairy cell leukemia and concomitant smoldering myeloma

Husam Jum’ah, David Viswanatha

Blood (2025) 145 (21): 2533.

https://doi.org/10.1182/blood.2025028465

Published: 2025

Journal Articles

The Mutational Landscape of Polycythemia Vera and Its Phenotypic and Prognostic Correlates

Masooma S Rana, Moazah Iftikhar, Yamna Jadoon, Maymona Abdelmagid, David Viswanatha, Rong He, Kaaren K. Reichard, Animesh D. Pardanani, Naseema Gangat, Ayalew Tefferi

Blood (2024) 144 (Supplement 1): 1797.

https://doi.org/10.1182/blood-2024-193119

Published: 2024

Journal Articles

PPM1D Somatic Mutations in Myeloid Neoplasms: Clinical Profile, Clonal Characteristics and Impact of Concurrent Somatic TP53 Mutations

Blood (2024) 144 (Supplement 1): 3218.

https://doi.org/10.1182/blood-2024-202688

Published: 2024

Journal Articles

Clinical Characteristics of Myeloproliferative Neoplasms in Patients with DDX41 MT Germline Predisposition Syndrome

Yael Kusne, Talha Badar, Terra L. Lasho, Ludovica Marando, Abhishek A. Mangaonkar, Christy Finke, James M. Foran, Aref Al-Kali, Hassan B Alkhateeb, Naseema Gangat, Jeanne Palmer, David Viswanatha, Mark R. Litzow, Animesh D. Pardanani, Ayalew Tefferi, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 3183.

https://doi.org/10.1182/blood-2024-202406

Published: 2024

Journal Articles

Prevalence and Clinical Features of Non-Myeloid Neoplasms in Patients with DDX41 Mutant Germline Predisposition Syndrome

Blood (2024) 144 (Supplement 1): 440.

https://doi.org/10.1182/blood-2024-203879

Published: 2024

Journal Articles

Clinical Outcome and Molecular Profile in Patients with DDX41 Mutation Hotspots: A Retrospective Study of 82 Patients

Nadia Toumeh, Yazan Jabban, Ahmad Nanaa, Rong He, David Viswanatha, Dragan Jevremovic, James M. Foran, Cecilia Y. Arana Yi, Antoine N. Saliba, Mehrdad Hefazi, William J. Hogan, Mithun V Shah, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Hassan B Alkhateeb, Aref Al-Kali

Blood (2024) 144 (Supplement 1): 2869.

https://doi.org/10.1182/blood-2024-209413

Published: 2024

Journal Articles

DNMT3A Mutant Clonal Hematopoiesis in Vexas Syndrome Epigenetically Potentiates IL-13 and IL-15 Inflammatory Pathways and Is Associated with Increased Mortality

Blood (2024) 144 (Supplement 1): 2686.

https://doi.org/10.1182/blood-2024-204334

Published: 2024

Journal Articles

STAG2 and PHF6 : Comparison of 2 X-Linked Gene Mutations in Myeloid Neoplasms

Bahga Katamesh, Amrutha Mittapalli, Rong He, David Viswanatha, Dragan Jevremovic, Mehrdad Hefazi, Antoine Saliba, Abhishek A Mangaonkar, Kebede Begna, William J. Hogan, Naseema Gangat, Mrinal M. Patnaik, Mithun V Shah, Ayalew Tefferi, Mark R. Litzow, Hassan Alkhateeb, Aref Al-Kali

Blood (2023) 142 (Supplement 1): 4304.

https://doi.org/10.1182/blood-2023-178244

Published: 2023

Journal Articles

Clinical and Molecular Spectrum of Somatic Mosaic States in DDX41 mutant Germline Predisposition Syndromes

Talha Badar, Terra L Lasho, Yael Kusne, Ludovica Marando, Abhishek A Mangaonkar, Christy M Finke, James M. Foran, Aref Al-Kali, Hassan Alkhateeb, Naseema Gangat, Rong He, David Viswanatha, Mark R. Litzow, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4618.

https://doi.org/10.1182/blood-2023-187310

Published: 2023

Journal Articles

Spectrum of clonal hematopoiesis in VEXAS syndrome

Blood (2023) 142 (3): 244–259.

https://doi.org/10.1182/blood.2022018774

Published: 2023

Includes: Supplemental data

Journal Articles

PD-1 Expression in Chronic Lymphocytic Leukemia and Large B-Cell Richter Transformation (DLBCL-RT): A Distinguishing Feature for DLBCL-RT and Promising Surrogate Marker for Clonal Relatedness

Rong He, MD, Wei Ding, MD PhD, David Viswanatha, MD, Dong Chen, MD PhD, Min Shi, MD PhD, Daniel L. Van Dyke, PhD, Linda N Dao, MD, Sameer A. Parikh, MD, Tait D Shanafelt, MD, Timothy G. Call, MD, Stephen M Ansell, MD PhD, Jose F. Leis, MD PhD, Ming Mai, MS, Curtis A. Hanson, MD, Karen L Rech, MD

Blood (2017) 130 (Supplement 1): 4286.

https://doi.org/10.1182/blood.V130.Suppl_1.4286.4286

Published: 2017

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Decoding DDX41: Clinical impact of germline and somatic mutations in 77 high-risk myeloid neoplasm patients

Molecular association with elevated LDH levels in patients with AML

Interplay between mutant DNMT3A and UBA1 worsens survival through altered inflammatory and metabolic pathways

Insights into clonal and CBC changes at disease evolution among ccus patients

Clinicopathologic features of myeloid neoplasms and pre-neoplasms with isolated ZRSR2 mutations

Prevalence, clinical correlates and clonal inferences of concurrent splicing factor mutations in patients with myeloid neoplasms

Disease stage-specific mutational landscape in essential thrombocythemia and prognostic correlates: A Mayo Clinic study of 500 NGS-informative cases

Clinical NGS detection of TP53 mutations in chronic phase primary myelofibrosis: Comparative analyses of genotype and prognosis

Causes of death in DDX41-mutated myeloid neoplasms: A retrospective study

Classic hairy cell leukemia and concomitant smoldering myeloma

The Mutational Landscape of Polycythemia Vera and Its Phenotypic and Prognostic Correlates

PPM1D Somatic Mutations in Myeloid Neoplasms: Clinical Profile, Clonal Characteristics and Impact of Concurrent Somatic TP53 Mutations

Clinical Characteristics of Myeloproliferative Neoplasms in Patients with DDX41 MT Germline Predisposition Syndrome

Prevalence and Clinical Features of Non-Myeloid Neoplasms in Patients with DDX41 Mutant Germline Predisposition Syndrome

Clinical Outcome and Molecular Profile in Patients with DDX41 Mutation Hotspots: A Retrospective Study of 82 Patients

DNMT3A Mutant Clonal Hematopoiesis in Vexas Syndrome Epigenetically Potentiates IL-13 and IL-15 Inflammatory Pathways and Is Associated with Increased Mortality

STAG2 and PHF6 : Comparison of 2 X-Linked Gene Mutations in Myeloid Neoplasms

Clinical and Molecular Spectrum of Somatic Mosaic States in DDX41 mutant Germline Predisposition Syndromes

Spectrum of clonal hematopoiesis in VEXAS syndrome

PD-1 Expression in Chronic Lymphocytic Leukemia and Large B-Cell Richter Transformation (DLBCL-RT): A Distinguishing Feature for DLBCL-RT and Promising Surrogate Marker for Clonal Relatedness

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