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Journal Articles

High-dose IV ascorbic acid therapy in CCUS patients with TET2 mutations

Zhuoer Xie, Jenna Fernandez, Terra L Lasho, Christy M. Finke, Michelle Amundson, Kristen McCullough, Betsy LaPlant, Abhishek A Mangaonkar, Naseema Gangat, Kaaren K Reichard, Michelle Ann Elliott, Thomas E. Witzig, Mrinal M. Patnaik

Blood blood.2024024962.

https://doi.org/10.1182/blood.2024024962

Published: 2024

Includes: Supplemental data

Journal Articles

Phase II Study Assessing Safety and Preliminary Efficacy of High Dose Intravenous Ascorbic Acid in Patients with TET2 Mutant Clonal Cytopenias

Zhuoer Xie, Kristen McCullough, Terra L Lasho, Jenna A. Fernandez, Christy M Finke, Michelle Renee Amundson, Betsy LaPlant, Abhishek Mangaokar, Naseema Gangat, Kaaren K. Reichard, Michelle Ann Elliott, Thomas E. Witzig, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4611.

https://doi.org/10.1182/blood-2023-186595

Published: 2023

Journal Articles

Prognostic Relevance of Truncating ASXL1 Mutations and ASXL1 -Integrated Molecular Models in Proliferative CMML

Clifford M Csizmar, Mark Gurney, Terra L Lasho, Rashmi Kanagal-Shamanna, Kelly S. Chien, Danielle E. Hammond, Christy M Finke, Abhishek A Mangaonkar, Aref Al-Kali, Naseema Gangat, Ayalew Tefferi, Hassan Alkhateeb, Guillermo Garcia-Manero, Guillermo Montalban-Bravo, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 3241.

https://doi.org/10.1182/blood-2023-186881

Published: 2023

Journal Articles

Venetoclax (VEN) Improves Response Rates but Not Survival in Patients with Chronic Myelomonocytic Leukemia (CMML) Treated with Hypomethylating Agents (HMA): A Multicenter, Propensity Score Analysis

Blood (2023) 142 (Supplement 1): 321.

https://doi.org/10.1182/blood-2023-181795

Published: 2023

Journal Articles

Distribution of Chromosome-Arm Specific Telomere Length in Patients with Telomere Biology Disorders

Alejandro Ferrer, Zachary D Stephens, Susan M. Geyer, Rachel A Simon, Terra L Lasho, Christy M Finke, Brittany Burnap, Lindsay A Mulvihill, Tammy M McAllister, Carolyn R. Rohrer Vitek, Konstantinos N Lazaridis, Angita Jain, Eric W Klee, Jean-Pierre A Kocher, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4103.

https://doi.org/10.1182/blood-2023-187486

Published: 2023

Journal Articles

Targeting Oncogenic Enhancers in ASXL1 -Mutant Chronic Myelomonocytic Leukemia

Terra L Lasho, Christy M Finke, Jenna A. Fernandez, Christopher T. Schmitz, Karl J. Clark, Claes Wahlestedt, Judy Chiao, Abhishek A Mangaonkar, Mrinal M. Patnaik, Moritz Binder

Blood (2023) 142 (Supplement 1): 1413.

https://doi.org/10.1182/blood-2023-178083

Published: 2023

Journal Articles

ASXL1 / TET2 Genotype-Based Risk Stratification Outperforms ASXL1 Mutational Impact and Is Independent of Mutant Variant Allele Fractions (VAF) in CMML

Clifford M Csizmar, Mark Gurney, Rashmi Kanagal-Shamanna, Kelly S. Chien, Danielle E. Hammond, Terra L Lasho, Christy M Finke, Christopher Dean, Abhishek A Mangaonkar, Naseema Gangat, Ayalew Tefferi, Hassan Alkhateeb, Guillermo Garcia-Manero, Guillermo Montalban-Bravo, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4615.

https://doi.org/10.1182/blood-2023-187235

Published: 2023

Journal Articles

Clinical and Molecular Spectrum of Somatic Mosaic States in DDX41 mutant Germline Predisposition Syndromes

Talha Badar, Terra L Lasho, Yael Kusne, Ludovica Marando, Abhishek A Mangaonkar, Christy M Finke, James M. Foran, Aref Al-Kali, Hassan Alkhateeb, Naseema Gangat, Rong He, David Viswanatha, Mark R. Litzow, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4618.

https://doi.org/10.1182/blood-2023-187310

Published: 2023

Journal Articles

Functional Testing of Variants of Uncertain Significance in TERC, TERT ,and RTEL1 from Adult Patients with Telomere Biology Disorders

Rachel A Simon, Christy M Finke, Terra L Lasho, Christopher T. Schmitz, Jenna A Fernandez, Eva M Carmona-Porquera, Mark E Wylam, Thomas E. Witzig, Tammy M McAllister, Carolyn R. Rohrer Vitek, Konstantinos N Lazaridis, Abhishek A Mangaonkar, Mrinal M. Patnaik, Alejandro Ferrer

Blood (2023) 142 (Supplement 1): 1365.

https://doi.org/10.1182/blood-2023-190153

Published: 2023

Journal Articles

Genetic Complementation Studies Reveal That Many Disease-Associated DDX41 Variants Do Not Cause Loss of Protein Function

Timothy Chlon, Emily Stepanchick, Christy M Finke, Terra L Lasho, Talha Badar, Alejandro Ferrer, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4104.

https://doi.org/10.1182/blood-2023-181881

Published: 2023

Journal Articles

Cellular Interactions within Clonal Dendritic Cell Aggregates Drive Immune Tolerance in Chronic Myelomonocytic Leukemia Bone Marrow Microenvironment

Abhishek A Mangaonkar, Terra L Lasho, Justin Boysen, Christy M Finke, Jenna A. Fernandez, Jose. C. Villasboas, Christopher Dean, Alejandro Ferrer, Moritz Binder, Liguo Wang, Jeong-Heon Lee, Kaaren K. Reichard, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4077.

https://doi.org/10.1182/blood-2023-186856

Published: 2023

Journal Articles

Myeloproliferative Neoplasms in Young Patients: The Mayo Clinic Experience with 361 Cases Age 40 Years or Younger

Natasha Szuber, MD, Mythri Mudireddy, MBBS, Maura Nicolosi, MD, Domenico Penna, MD, Rangit Reddy Vallapureddy, MBBS, Terra L. Lasho, PhD, Christy Finke, BS, Curtis A. Hanson, MD, Rhett P. Ketterling, Animesh Pardanani, MBBS, PhD, Naseema Gangat, MBBS, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3033.

https://doi.org/10.1182/blood-2018-99-117540

Published: 2018

Journal Articles

Serum Erythropoietin Levels in Essential Thrombocythemia: Phenotypic and Prognostic Correlates

Natasha Szuber, MD, Sravanthi Lavu, MBBS, Mythri Mudireddy, MBBS, Maura Nicolosi, MD, Domenico Penna, MD, Rangit Vallapureddy, MBBS, Terra L. Lasho, PhD, Christy Finke, BS, Curtis A. Hanson, MD, Rhett P. Ketterling, Animesh Pardanani, MBBS, PhD, Naseema Gangat, MBBS, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3034.

https://doi.org/10.1182/blood-2018-99-109721

Published: 2018

Journal Articles

3,023 Mayo Clinic Patients with Myeloproliferative Neoplasms: Risk-Stratified Comparison of Survival and Outcomes Data Among Disease Subgroups

Natasha Szuber, MD, Mythri Mudireddy, MBBS, Maura Nicolosi, MD, Domenico Penna, MD, Rangit Vallapureddy, MBBS, Terra L. Lasho, PhD, Christy Finke, BS, Kebede H. Begna, MD, Michelle A. Elliott, MD, C. Christopher Hook, MD, Alexandra Wolanskyj, MD, Mrinal M. Patnaik, MD MBBS, Curtis A. Hanson, MD, Rhett P. Ketterling, Shireen Sirhan, MD, Animesh Pardanani, MBBS, PhD, Naseema Gangat, MBBS, Lambert Busque, MD, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3035.

https://doi.org/10.1182/blood-2018-99-109740

Published: 2018

Journal Articles

MPL -Mutated Essential Thrombocythemia: A Morphologic Reappraisal

Natasha Szuber, MD, Curtis A. Hanson, MD, Terra L. Lasho, PhD, Christy Finke, BS, Rhett P. Ketterling, Animesh Pardanani, MBBS, PhD, Naseema Gangat, MBBS, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3036.

https://doi.org/10.1182/blood-2018-99-115272

Published: 2018

Journal Articles

Cytogenetic Abnormalities in Systemic Mastocytosis: Who Subcategory-Specific Incidence and Prognostic Impact Among 348 Informative Cases

Sahrish Shah, MD, Animesh Pardanani, MBBS, PhD, Yoseph Elala, MD, Terra L. Lasho, PhD, Mrinal M. Patnaik, MD MBBS, Kaaren K. Reichard, MD, Curtis A. Hanson, MD, Rhett P. Ketterling, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3050.

https://doi.org/10.1182/blood-2018-99-112628

Published: 2018

Journal Articles

Mutations and Thrombosis in Essential Thrombocythemia and Polycythemia Vera: Mayo-Careggi Alliance Study

Paola Guglielmelli, MD PhD, Naseema Gangat, MBBS, Giacomo Coltro, MD, Terra L. Lasho, PhD, Giuseppe Gaetano Loscocco, MD, Christy Finke, BS, Benedetta Sordi, MD, Mythri Mudireddy, MBBS, Giada Rotunno, PhD, Natasha Szuber, MD, Annalisa Pacilli, PhD, Rangit Reddy Vallapureddy, MBBS, Maura Nicolosi, MD, Domenico Penna, MD, Curtis A. Hanson, MD, Rhett P. Ketterling, Animesh Pardanani, MBBS, PhD, Alessandro M. Vannucchi, MD, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3040.

https://doi.org/10.1182/blood-2018-99-110045

Published: 2018

Journal Articles

Risk Factors for Leukemic Transformation Among 1,306 Patients with Primary Myelofibrosis: Mutations Predict Early Events

Rangit Reddy Vallapureddy, MBBS, Mythri Mudireddy, MBBS, Natasha Szuber, MD, Domenico Penna, MD, Maura Nicolosi, MD, Terra L. Lasho, PhD, Christy Finke, BS, Curtis A. Hanson, MD, Rhett P. Ketterling, Kebede H. Begna, MD, Naseema Gangat, MBBS, Animesh Pardanani, MBBS, PhD, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3044.

https://doi.org/10.1182/blood-2018-99-109895

Published: 2018

Journal Articles

The Germline JAK2 GGCC (46/1) Haplotype and Survival Among 414 Molecularly-Annotated Patients with Primary Myelofibrosis

Ayalew Tefferi, MD, Terra L. Lasho, PhD, Christy Finke, BS, Mythri Mudireddy, MBBS, Natasha Szuber, MD, Rangit Reddy Vallapureddy, MBBS, Domenico Penna, MD, Curtis A. Hanson, MD, Rhett P. Ketterling, Naseema Gangat, MBBS, Animesh Pardanani, MBBS, PhD

Blood (2018) 132 (Supplement 1): 1761.

https://doi.org/10.1182/blood-2018-99-110046

Published: 2018

Journal Articles

Cytogenetic Clonal Evolution in Myeloproliferative Neoplasms: Contexts and Prognostic Impact Among 650 Patients with Serial Bone Marrow Biopsies

Maura Nicolosi, MD, Domenico Penna, MD, Mythri Mudireddy, MBBS, Natasha Szuber, MD, Rangit Vallapureddy, MBBS, Terra L. Lasho, PhD, Christy Finke, BS, Curtis A. Hanson, MD, Animesh Pardanani, MBBS, PhD, Naseema Gangat, MBBS, Rhett P. Ketterling, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 4291.

https://doi.org/10.1182/blood-2018-99-109714

Published: 2018

NARROW

High-dose IV ascorbic acid therapy in CCUS patients with TET2 mutations

Phase II Study Assessing Safety and Preliminary Efficacy of High Dose Intravenous Ascorbic Acid in Patients with TET2 Mutant Clonal Cytopenias

Prognostic Relevance of Truncating ASXL1 Mutations and ASXL1 -Integrated Molecular Models in Proliferative CMML

Venetoclax (VEN) Improves Response Rates but Not Survival in Patients with Chronic Myelomonocytic Leukemia (CMML) Treated with Hypomethylating Agents (HMA): A Multicenter, Propensity Score Analysis

Distribution of Chromosome-Arm Specific Telomere Length in Patients with Telomere Biology Disorders

Targeting Oncogenic Enhancers in ASXL1 -Mutant Chronic Myelomonocytic Leukemia

ASXL1 / TET2 Genotype-Based Risk Stratification Outperforms ASXL1 Mutational Impact and Is Independent of Mutant Variant Allele Fractions (VAF) in CMML

Clinical and Molecular Spectrum of Somatic Mosaic States in DDX41 mutant Germline Predisposition Syndromes

Functional Testing of Variants of Uncertain Significance in TERC, TERT ,and RTEL1 from Adult Patients with Telomere Biology Disorders

Genetic Complementation Studies Reveal That Many Disease-Associated DDX41 Variants Do Not Cause Loss of Protein Function

Cellular Interactions within Clonal Dendritic Cell Aggregates Drive Immune Tolerance in Chronic Myelomonocytic Leukemia Bone Marrow Microenvironment

Myeloproliferative Neoplasms in Young Patients: The Mayo Clinic Experience with 361 Cases Age 40 Years or Younger

Serum Erythropoietin Levels in Essential Thrombocythemia: Phenotypic and Prognostic Correlates

3,023 Mayo Clinic Patients with Myeloproliferative Neoplasms: Risk-Stratified Comparison of Survival and Outcomes Data Among Disease Subgroups

MPL -Mutated Essential Thrombocythemia: A Morphologic Reappraisal

Cytogenetic Abnormalities in Systemic Mastocytosis: Who Subcategory-Specific Incidence and Prognostic Impact Among 348 Informative Cases

Mutations and Thrombosis in Essential Thrombocythemia and Polycythemia Vera: Mayo-Careggi Alliance Study

Risk Factors for Leukemic Transformation Among 1,306 Patients with Primary Myelofibrosis: Mutations Predict Early Events

The Germline JAK2 GGCC (46/1) Haplotype and Survival Among 414 Molecularly-Annotated Patients with Primary Myelofibrosis

Cytogenetic Clonal Evolution in Myeloproliferative Neoplasms: Contexts and Prognostic Impact Among 650 Patients with Serial Bone Marrow Biopsies

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American Society of Hematology

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